𝕏

Task 55702845

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_333-conf_495_0
Workunit 26452232
Created 1 Jul 2024, 16:17:02 UTC
Sent 2 Jul 2024, 13:34:45 UTC
Report deadline 5 Jul 2024, 13:34:45 UTC
Received 3 Jul 2024, 2:48:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241293
Run time 1 hours 47 min 18 sec
CPU time 1 hours 46 min 44 sec
Validate state Valid
Credit 43.23
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.41 MB
Peak swap size 3.69 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_333-conf_495.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_333-conf_495_0_r1578387132_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_333-conf_495_0_r1578387132_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.973604
     * GNaL_b in INaL: 0.005485
     * Gto_b in Ito: 0.084114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031905
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.164903
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.272050
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036047
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8604513, states[0] = -53.258356, states[40]= 0.000096
Saving checkpoint... 
Iteration: 17519693, states[0] = 28.594513, states[40]= 0.001027
Saving checkpoint... 
Iteration: 25753705, states[0] = -30.237965, states[40]= 0.000497
Saving checkpoint... 
Iteration: 33998586, states[0] = 35.022295, states[40]= 1.088326
Saving checkpoint... 
Iteration: 42552775, states[0] = 7.865645, states[40]= 0.000111
Saving checkpoint... 
Iteration: 50909885, states[0] = -21.118602, states[40]= 0.000324
Saving checkpoint... 
Iteration: 59636220, states[0] = -84.711047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68215024, states[0] = 8.853696, states[40]= 0.000069
Saving checkpoint... 
Iteration: 76673838, states[0] = 29.544900, states[40]= 0.011190
Saving checkpoint... 
Iteration: 85152135, states[0] = -84.988636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93539366, states[0] = 13.361152, states[40]= 0.000022
Saving checkpoint... 
Iteration: 101945927, states[0] = -79.532242, states[40]= 0.000002
Saving checkpoint... 
Iteration: 109965401, states[0] = -84.763264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117943105, states[0] = -78.261464, states[40]= 0.000003
Saving checkpoint... 
Iteration: 126065005, states[0] = -16.764770, states[40]= 0.000272
Saving checkpoint... 
Iteration: 134537953, states[0] = 11.400026, states[40]= 0.000034
Saving checkpoint... 
Iteration: 143314527, states[0] = -85.014814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151440544, states[0] = -79.275169, states[40]= 0.000002
Saving checkpoint... 
Iteration: 159992269, states[0] = 28.421279, states[40]= 0.127888
Saving checkpoint... 
Iteration: 168517970, states[0] = 21.900863, states[40]= 0.000010
Saving checkpoint... 
Iteration: 177271742, states[0] = -79.775029, states[40]= 0.000002
Saving checkpoint... 
Iteration: 185426551, states[0] = -63.920481, states[40]= 0.000020
Saving checkpoint... 
Iteration: 193781924, states[0] = -84.460186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 202377989, states[0] = -0.057909, states[40]= 0.000224
Saving checkpoint... 
Iteration: 210585589, states[0] = -56.641522, states[40]= 0.000045
Saving checkpoint... 
Iteration: 219156535, states[0] = 29.257474, states[40]= 0.034683
Saving checkpoint... 
Iteration: 227056052, states[0] = -18.540530, states[40]= 0.000257
Saving checkpoint... 
Iteration: 235904553, states[0] = -40.817941, states[40]= 0.000183
Saving checkpoint... 
Iteration: 244546616, states[0] = -7.432295, states[40]= 0.000325
Saving checkpoint... 
Iteration: 252726761, states[0] = -27.987174, states[40]= 0.000272
Saving checkpoint... 
Iteration: 261296966, states[0] = -84.946414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269875615, states[0] = -5.072757, states[40]= 0.000307
Saving checkpoint... 
Iteration: 278472435, states[0] = -49.849908, states[40]= 0.000003
Saving checkpoint... 
Iteration: 286927638, states[0] = -79.969238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 295447131, states[0] = -84.763481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303839389, states[0] = 20.978913, states[40]= 0.000007
Saving checkpoint... 
Iteration: 312405620, states[0] = -52.400648, states[40]= 0.000069
Saving checkpoint... 
Iteration: 320799615, states[0] = -85.034145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329569107, states[0] = -50.439954, states[40]= 0.000083
Saving checkpoint... 
Iteration: 337792234, states[0] = -84.974342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346240560, states[0] = -59.236662, states[40]= 0.000034
Saving checkpoint... 
Iteration: 354803239, states[0] = 28.451540, states[40]= 0.362253
Saving checkpoint... 
Iteration: 363093796, states[0] = -83.850201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371483641, states[0] = 28.381181, states[40]= 0.001264
Saving checkpoint... 
Iteration: 379813945, states[0] = 28.969530, states[40]= 0.002809
Saving checkpoint... 
Iteration: 387502154, states[0] = 18.335541, states[40]= 0.000006
Saving checkpoint... 
Iteration: 395878861, states[0] = -27.627508, states[40]= 0.000271
Saving checkpoint... 
Iteration: 404145113, states[0] = 28.908608, states[40]= 0.002547
Saving checkpoint... 
Iteration: 412456149, states[0] = -85.018962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421040049, states[0] = -23.442166, states[40]= 0.000256
Saving checkpoint... 
Iteration: 428841538, states[0] = 11.611036, states[40]= 0.000031
Saving checkpoint... 
Iteration: 437912133, states[0] = -79.528452, states[40]= 0.000002
Saving checkpoint... 
Iteration: 446442559, states[0] = -84.904907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455306135, states[0] = 29.027790, states[40]= 0.003088
Saving checkpoint... 
Iteration: 463730554, states[0] = -61.706000, states[40]= 0.000026
Saving checkpoint... 
Iteration: 471938516, states[0] = -84.884987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480625976, states[0] = 28.225389, states[40]= 0.177275
Saving checkpoint... 
Iteration: 488981705, states[0] = 24.169480, states[40]= 0.000038
Saving checkpoint... 
Iteration: 497484158, states[0] = 22.408697, states[40]= 0.000013
Saving checkpoint... 
Iteration: 505830489, states[0] = 13.942361, states[40]= 0.000018
Saving checkpoint... 
Iteration: 514183562, states[0] = -3.886514, states[40]= 0.000295
Saving checkpoint... 
Iteration: 522637829, states[0] = 27.461802, states[40]= 0.000487
Saving checkpoint... 
Iteration: 531090106, states[0] = -84.746480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539504303, states[0] = 6.098634, states[40]= 0.000097
Saving checkpoint... 
Iteration: 547698042, states[0] = -29.053486, states[40]= 0.000273
Saving checkpoint... 
Iteration: 556124630, states[0] = 29.452841, states[40]= 0.017785
Saving checkpoint... 
Iteration: 564667848, states[0] = 6.601228, states[40]= 0.000088
Saving checkpoint... 
Iteration: 572952225, states[0] = 28.758004, states[40]= 0.080365
Saving checkpoint... 
Iteration: 581355164, states[0] = -20.283337, states[40]= 0.000252
Saving checkpoint... 
Iteration: 590071496, states[0] = -83.915939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 598622005, states[0] = 29.451696, states[40]= 0.009746
Saving checkpoint... 
Iteration: 607307963, states[0] = 21.601955, states[40]= 0.000008
Saving checkpoint... 
Iteration: 615694429, states[0] = -33.423629, states[40]= 0.000258
Saving checkpoint... 
Iteration: 624347414, states[0] = -15.217756, states[40]= 0.000279
Saving checkpoint... 
Iteration: 632435049, states[0] = -85.014379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641317140, states[0] = 13.809893, states[40]= 0.000018
Saving checkpoint... 
Iteration: 649706066, states[0] = -53.505130, states[40]= 0.000062
Saving checkpoint... 
Iteration: 658397681, states[0] = -83.844229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666703209, states[0] = -51.956813, states[40]= 0.000072
Saving checkpoint... 
Iteration: 675330189, states[0] = 0.473733, states[40]= 0.000212
Saving checkpoint... 
Iteration: 683919771, states[0] = -84.901885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692460806, states[0] = 24.454595, states[40]= 0.000046
Saving checkpoint... 
Iteration: 701345954, states[0] = -24.282246, states[40]= 0.000259
Saving checkpoint... 
Iteration: 710434774, states[0] = 28.260752, states[40]= 0.310134
Saving checkpoint... 
Iteration: 719023024, states[0] = -40.939096, states[40]= 0.000181
Saving checkpoint... 
Iteration: 727445040, states[0] = 29.141987, states[40]= 0.003768
Saving checkpoint... 
Iteration: 735253436, states[0] = -84.960176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743838239, states[0] = -19.286362, states[40]= 0.000254
Saving checkpoint... 
Iteration: 752215780, states[0] = -81.107887, states[40]= 0.000002
Saving checkpoint... 
Iteration: 761197043, states[0] = -56.383962, states[40]= 0.000046
Saving checkpoint... 
Iteration: 769382822, states[0] = -82.495763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777848386, states[0] = -38.146770, states[40]= 0.000214
Saving checkpoint... 
Iteration: 786651432, states[0] = 1.438952, states[40]= 0.000190
Saving checkpoint... 
Iteration: 795159562, states[0] = -9.250501, states[40]= 0.000324
Saving checkpoint... 
Iteration: 803748069, states[0] = -84.971635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812067557, states[0] = -84.816584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820481207, states[0] = 1.611742, states[40]= 0.000186
Saving checkpoint... 
Iteration: 828902395, states[0] = -84.857620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837486139, states[0] = -5.838763, states[40]= 0.000316
Saving checkpoint... 
Iteration: 845877144, states[0] = -83.334897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854934177, states[0] = 28.713118, states[40]= 0.001892
Saving checkpoint... 
Iteration: 863049024, states[0] = -84.461333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871368633, states[0] = -79.295918, states[40]= 0.000002
Saving checkpoint... 
Iteration: 879614327, states[0] = 21.457963, states[40]= 0.000008
Saving checkpoint... 
Iteration: 888269000, states[0] = 27.041485, states[40]= 0.000331
Saving checkpoint... 
Iteration: 896629278, states[0] = 10.764304, states[40]= 0.000038
Saving checkpoint... 
Iteration: 905356727, states[0] = -67.105284, states[40]= 0.000014
Saving checkpoint... 
Iteration: 913830187, states[0] = -31.909488, states[40]= 0.000267
Saving checkpoint... 
Iteration: 922486166, states[0] = -17.994119, states[40]= 0.000260
Saving checkpoint... 
Iteration: 931052638, states[0] = -84.764712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940060087, states[0] = -84.877178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948442341, states[0] = 20.562953, states[40]= 0.000006
Saving checkpoint... 
Iteration: 957126063, states[0] = 8.634998, states[40]= 0.000060
Saving checkpoint... 
Iteration: 965452012, states[0] = 13.394485, states[40]= 0.000020
Saving checkpoint... 
Iteration: 973860190, states[0] = -81.001907, states[40]= 0.000002
Saving checkpoint... 
Iteration: 982385175, states[0] = -84.823890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990866351, states[0] = -84.147698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000230685, states[0] = -84.982758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009173817, states[0] = -58.533378, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1018155517, states[0] = -35.208005, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1027198352, states[0] = -84.384790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036140083, states[0] = -15.950264, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1044368223, states[0] = -84.623219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044985569, states[0] = -34.395908, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1053382953, states[0] = -84.880356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062081845, states[0] = 28.205587, states[40]= 0.001014
Saving checkpoint... 
Iteration: 1070412081, states[0] = 28.859374, states[40]= 0.002307
Saving checkpoint... 
Iteration: 1079004649, states[0] = -65.012058, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1087305048, states[0] = -20.952813, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1096064284, states[0] = 28.204808, states[40]= 0.186450
Saving checkpoint... 
Iteration: 1104478987, states[0] = -33.539235, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1113347790, states[0] = -82.090297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121598213, states[0] = 16.600956, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1130529672, states[0] = -84.699291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138905368, states[0] = 28.823643, states[40]= 0.002196
Saving checkpoint... 
Iteration: 1147710182, states[0] = -84.913144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156128501, states[0] = -16.557842, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1164856474, states[0] = -84.624674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173282587, states[0] = -1.844479, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1181880334, states[0] = -84.983229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190262892, states[0] = 13.380195, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1198478623, states[0] = -45.608952, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1207168246, states[0] = -79.086965, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1215732564, states[0] = 28.392689, states[40]= 0.001251
Saving checkpoint... 
Iteration: 1224525713, states[0] = -84.782630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232950909, states[0] = -11.786500, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1241895407, states[0] = 28.739937, states[40]= 0.001940
Saving checkpoint... 
Iteration: 1250107267, states[0] = -0.782189, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1258552036, states[0] = 29.172376, states[40]= 0.042478
Saving checkpoint... 
Iteration: 1266801412, states[0] = -40.680702, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1274923895, states[0] = 11.415972, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1283559813, states[0] = 28.169647, states[40]= 0.000971
Saving checkpoint... 
Iteration: 1292303790, states[0] = -47.213730, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1300712516, states[0] = 28.694984, states[40]= 0.088357
Saving checkpoint... 
Iteration: 1309232535, states[0] = 24.428032, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1317847744, states[0] = -84.747687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326162328, states[0] = -83.245450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335004715, states[0] = -84.567836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1343460749, states[0] = -41.122196, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1352073349, states[0] = 17.748587, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1360400862, states[0] = 20.736136, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1369002870, states[0] = -84.615284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377479258, states[0] = -71.776469, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1386292435, states[0] = -44.609662, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1394903318, states[0] = 17.174039, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1403391279, states[0] = 23.658147, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1411934111, states[0] = -13.385261, states[40]= 0.000296
Saving checkpoint... 
Iteration: 1420366649, states[0] = 28.540910, states[40]= 0.108924
Saving checkpoint... 
Iteration: 1428821363, states[0] = -83.922602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437357444, states[0] = 34.382976, states[40]= 0.895558
Saving checkpoint... 
Iteration: 1445211013, states[0] = 27.932986, states[40]= 0.000754
Saving checkpoint... 
Iteration: 1445716892, states[0] = 25.419372, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1454794072, states[0] = -55.935425, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1463638939, states[0] = -74.224521, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1472262645, states[0] = -15.196233, states[40]= 0.000279
Saving checkpoint... 
Iteration: 1481014486, states[0] = -84.938506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489836811, states[0] = -84.823227, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498448917, states[0] = -45.964408, states[40]= 0.000124
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.853412
 - CaMKt in component CaMK (millimolar): 0.216887
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.320631
 - nass in component intracellular_ions (millimolar): 7.320985
 - ki in component intracellular_ions (millimolar): 143.798350
 - kss in component intracellular_ions (millimolar): 143.798314
 - cansr in component intracellular_ions (millimolar): 3.335653
 - cajsr in component intracellular_ions (millimolar): 1.925632
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009951
 - hf in component INa (dimensionless): 0.584510
 - hs in component INa (dimensionless): 0.583469
 - j in component INa (dimensionless): 0.554664
 - hsp in component INa (dimensionless): 0.332068
 - jp in component INa (dimensionless): 0.513512
 - mL in component INaL (dimensionless): 0.000334
 - hL in component INaL (dimensionless): 0.184577
 - hLp in component INaL (dimensionless): 0.075415
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999238
 - iS in component Ito (dimensionless): 0.131914
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999239
 - iSp in component Ito (dimensionless): 0.147633
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.678892
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.929445
 - jca in component ICaL (dimensionless): 0.912043
 - ffp in component ICaL (dimensionless): 0.998969
 - fcafp in component ICaL (dimensionless): 0.999941
 - nca in component ICaL (dimensionless): 0.041868
 - xrf in component IKr (dimensionless): 0.099187
 - xrs in component IKr (dimensionless): 0.871858
 - xs1 in component IKs (dimensionless): 0.569484
 - xs2 in component IKs (dimensionless): 0.006996
 - xk1 in component IK1 (dimensionless): 0.996734
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:48:39 (171736): called boinc_finish(0)

</stderr_txt>
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