𝕏

Task 55702715

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_95_0
Workunit 26452167
Created 1 Jul 2024, 16:17:02 UTC
Sent 2 Jul 2024, 13:34:45 UTC
Report deadline 5 Jul 2024, 13:34:45 UTC
Received 2 Jul 2024, 21:11:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241293
Run time 1 hours 46 min 55 sec
CPU time 1 hours 45 min 9 sec
Validate state Valid
Credit 42.72
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.06 MB
Peak swap size 4.31 MB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_95.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_95_0_r364659283_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_95_0_r364659283_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.638763
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.087959
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031516
     * GKs_b in IKs: 0.001892
     * GK1_b in IK1: 0.162436
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.046866
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036354
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8603496, states[0] = -86.765736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16810107, states[0] = -86.703437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25751702, states[0] = -86.639464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33878569, states[0] = -86.602432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42907872, states[0] = -86.584493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51629020, states[0] = -86.552350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59816584, states[0] = -86.534742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68732150, states[0] = -86.534803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76800644, states[0] = -86.525340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85077686, states[0] = -86.513240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93772623, states[0] = -86.497074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102603633, states[0] = -86.501701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111675459, states[0] = -86.488099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119968281, states[0] = -86.482513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128368441, states[0] = -86.435211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137159659, states[0] = -86.487176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145892709, states[0] = -86.476270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154044011, states[0] = 17.689664, states[40]= 0.004171
Saving checkpoint... 
Iteration: 162820077, states[0] = -86.488755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171473393, states[0] = -86.476859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180532396, states[0] = -86.476818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188986310, states[0] = -86.483804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197532067, states[0] = -86.474196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206330055, states[0] = -86.398487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214653201, states[0] = -86.483949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223087158, states[0] = -86.480332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231415746, states[0] = -86.474486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239416822, states[0] = -86.474300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248458090, states[0] = -86.460317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257149438, states[0] = -86.478466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265786234, states[0] = -86.469833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274441420, states[0] = -86.455371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283005967, states[0] = -86.481012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287972544, states[0] = -86.468275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296638686, states[0] = -86.482168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305525744, states[0] = -86.472217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314217538, states[0] = -86.247086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322472518, states[0] = -86.463275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331517481, states[0] = -86.472237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339846104, states[0] = -86.468981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348896534, states[0] = -86.482769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357236427, states[0] = -86.476383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365715313, states[0] = -86.470053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374389853, states[0] = -86.435243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382577729, states[0] = -86.478322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391077365, states[0] = -86.479332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399193745, states[0] = -86.477109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407975979, states[0] = -86.467992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417122752, states[0] = -86.478435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425937259, states[0] = -86.468240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433990124, states[0] = -86.467891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442207929, states[0] = -86.169104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450862506, states[0] = -86.483208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459203861, states[0] = -86.476901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467628107, states[0] = -86.470863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475791448, states[0] = -86.469324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484292731, states[0] = -86.359383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493025856, states[0] = -86.480305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501584194, states[0] = -86.471332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509937947, states[0] = -86.468212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518823225, states[0] = -86.483661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527491611, states[0] = -86.472436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535712354, states[0] = -86.470010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544609210, states[0] = -86.480467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552926169, states[0] = -86.482173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561720990, states[0] = -86.469924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570600660, states[0] = -86.479937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579006573, states[0] = -86.480664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587433667, states[0] = -86.473195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595997382, states[0] = -86.467807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604766875, states[0] = -86.483985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612720484, states[0] = -86.483821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621041395, states[0] = -86.479974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629588137, states[0] = -86.471262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638041142, states[0] = 18.410400, states[40]= 0.004223
Saving checkpoint... 
Iteration: 646762056, states[0] = -86.483982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655174010, states[0] = -86.477407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663519342, states[0] = -86.472062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672122480, states[0] = -17.322870, states[40]= 0.001052
Saving checkpoint... 
Iteration: 680726430, states[0] = -86.483857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689381515, states[0] = -86.473922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698073155, states[0] = 9.668664, states[40]= 0.004149
Saving checkpoint... 
Iteration: 706350725, states[0] = -86.412438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715139839, states[0] = -86.478039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723558924, states[0] = -86.471577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732270493, states[0] = -86.330664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740860399, states[0] = -86.483176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749125716, states[0] = -86.478303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758068576, states[0] = 11.140741, states[40]= 0.004169
Saving checkpoint... 
Iteration: 766851823, states[0] = -86.483285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775310371, states[0] = -86.475007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783844318, states[0] = -86.468837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791566298, states[0] = -86.471479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800378919, states[0] = -86.429589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808951883, states[0] = -86.481660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817760490, states[0] = -86.469520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826407661, states[0] = -86.443041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834778734, states[0] = -86.483910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843088622, states[0] = -86.479004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851214429, states[0] = -86.476631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859758949, states[0] = -86.469526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868308360, states[0] = -86.376481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876935217, states[0] = -86.481950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885223657, states[0] = -86.476460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893627617, states[0] = -86.470783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901853114, states[0] = -86.468747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910430344, states[0] = -86.451408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918349683, states[0] = -86.411672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926948117, states[0] = -86.481707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935316643, states[0] = -86.474876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943385985, states[0] = -86.473807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951935209, states[0] = -86.468144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961101370, states[0] = -86.478733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969576618, states[0] = -86.471326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978276519, states[0] = -86.338881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986677242, states[0] = -86.483062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994684124, states[0] = -86.483212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003573674, states[0] = -86.471353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012415592, states[0] = -86.446136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021151228, states[0] = -86.477764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029699825, states[0] = -86.470033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038280157, states[0] = -86.343682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046788740, states[0] = -86.483825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055776366, states[0] = -86.469338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064514937, states[0] = -86.470974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072841229, states[0] = -86.483357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080865155, states[0] = -86.483045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089416698, states[0] = -86.473336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098016920, states[0] = 21.665892, states[40]= 0.011188
Saving checkpoint... 
Iteration: 1105939420, states[0] = -86.468086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114528730, states[0] = -86.472940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123130602, states[0] = -86.478137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131518146, states[0] = -86.471987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140056633, states[0] = 14.589089, states[40]= 0.004152
Saving checkpoint... 
Iteration: 1148520660, states[0] = -86.471809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157005890, states[0] = -86.480567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165878427, states[0] = -86.468506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174666730, states[0] = -86.482757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183045011, states[0] = -86.479795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191257342, states[0] = -86.475812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199512300, states[0] = -86.472046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207890514, states[0] = -86.468409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215995323, states[0] = -86.467700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224414130, states[0] = -86.445535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232772078, states[0] = -86.483854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241647214, states[0] = -86.470512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249728799, states[0] = -86.469720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258660991, states[0] = -86.482575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267451960, states[0] = -86.472814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276179239, states[0] = -67.890470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1284994178, states[0] = -86.480769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293987558, states[0] = -86.467734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302491273, states[0] = -86.466882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311104846, states[0] = -86.478598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319702988, states[0] = -86.469947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328053938, states[0] = 15.302543, states[40]= 0.004142
Saving checkpoint... 
Iteration: 1336581598, states[0] = -86.478427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345274041, states[0] = -86.475498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354017559, states[0] = 21.664044, states[40]= 0.010251
Saving checkpoint... 
Iteration: 1362704894, states[0] = -86.483499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371589980, states[0] = -86.471099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380150472, states[0] = -40.454466, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1388454647, states[0] = -86.458569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396928697, states[0] = -86.481966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405481845, states[0] = -86.472393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414146463, states[0] = -37.066274, states[40]= 0.000202
Saving checkpoint... 
Iteration: 1422754666, states[0] = -86.483832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431295498, states[0] = -86.475124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439308291, states[0] = -86.474914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448271612, states[0] = -86.332088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456813997, states[0] = -86.483567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465499026, states[0] = -86.472161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473759900, states[0] = -86.469400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482687830, states[0] = -86.483194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490987195, states[0] = -86.480864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499343960, states[0] = -86.474336, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.343586
 - CaMKt in component CaMK (millimolar): 0.000890
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.041968
 - nass in component intracellular_ions (millimolar): 6.042012
 - ki in component intracellular_ions (millimolar): 145.954443
 - kss in component intracellular_ions (millimolar): 145.954432
 - cansr in component intracellular_ions (millimolar): 1.247607
 - cajsr in component intracellular_ions (millimolar): 1.247768
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008569
 - hf in component INa (dimensionless): 0.642493
 - hs in component INa (dimensionless): 0.642494
 - j in component INa (dimensionless): 0.642496
 - hsp in component INa (dimensionless): 0.393524
 - jp in component INa (dimensionless): 0.642498
 - mL in component INaL (dimensionless): 0.000252
 - hL in component INaL (dimensionless): 0.461957
 - hLp in component INaL (dimensionless): 0.272542
 - a in component Ito (dimensionless): 0.001110
 - iF in component Ito (dimensionless): 0.999417
 - iS in component Ito (dimensionless): 0.985380
 - ap in component Ito (dimensionless): 0.000566
 - iFp in component Ito (dimensionless): 0.999417
 - iSp in component Ito (dimensionless): 0.991516
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997447
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001255
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020552
 - xs1 in component IKs (dimensionless): 0.037895
 - xs2 in component IKs (dimensionless): 0.000229
 - xk1 in component IK1 (dimensionless): 0.997139
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:10:56 (160876): called boinc_finish(0)

</stderr_txt>
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