𝕏

Task 55699831

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_92_1
Workunit 26450727
Created 1 Jul 2024, 16:15:43 UTC
Sent 2 Jul 2024, 13:08:59 UTC
Report deadline 5 Jul 2024, 13:08:59 UTC
Received 3 Jul 2024, 4:19:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235353
Run time 3 hours 16 min 33 sec
CPU time 2 hours 19 min 54 sec
Validate state Valid
Credit 46.63
Device peak FLOPS 4.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.18 MB
Peak swap size 5.27 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_92.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_92_1_r1830508268_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_92_1_r1830508268_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 104.617114
     * GNaL_b in INaL: 0.005622
     * Gto_b in Ito: 0.088495
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032021
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.040630
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.495424
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031921
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9196853, states[0] = -83.906876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17187550, states[0] = -79.193417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26284239, states[0] = -90.704032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34396728, states[0] = -91.351343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42300614, states[0] = -90.761622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50304678, states[0] = -90.765177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58744212, states[0] = -88.823855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68090219, states[0] = -3.342223, states[40]= 0.003843
Saving checkpoint... 
Iteration: 76237349, states[0] = -88.105161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84370372, states[0] = -91.101215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92405789, states[0] = -91.200374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101449146, states[0] = -91.271913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109413790, states[0] = -91.204233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117511002, states[0] = 27.518360, states[40]= 0.033869
Saving checkpoint... 
Iteration: 125579053, states[0] = 4.313942, states[40]= 0.004291
Saving checkpoint... 
Iteration: 133587475, states[0] = -1.047149, states[40]= 0.004144
Saving checkpoint... 
Iteration: 142579572, states[0] = 4.029925, states[40]= 0.004303
Saving checkpoint... 
Iteration: 150819421, states[0] = -90.772074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158724281, states[0] = -86.212401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166725714, states[0] = -86.437884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176109663, states[0] = -21.551210, states[40]= 0.001146
Saving checkpoint... 
Iteration: 184266354, states[0] = -89.845304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192427042, states[0] = -91.208741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200422474, states[0] = -91.199552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208525271, states[0] = 26.126844, states[40]= 0.001396
Saving checkpoint... 
Iteration: 217878533, states[0] = -91.082696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226024102, states[0] = 26.405413, states[40]= 0.001487
Saving checkpoint... 
Iteration: 234011311, states[0] = 27.549662, states[40]= 0.030547
Saving checkpoint... 
Iteration: 242022305, states[0] = 26.790483, states[40]= 0.001757
Saving checkpoint... 
Iteration: 250899597, states[0] = -91.145635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258920137, states[0] = -91.193045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267107917, states[0] = -19.794359, states[40]= 0.001212
Saving checkpoint... 
Iteration: 275057938, states[0] = 14.506857, states[40]= 0.003007
Saving checkpoint... 
Iteration: 283294107, states[0] = -90.485143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292294801, states[0] = -90.495140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300433707, states[0] = -91.217603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308655613, states[0] = -61.727459, states[40]= 0.000010
Saving checkpoint... 
Iteration: 316791513, states[0] = -90.445331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325061607, states[0] = 12.949227, states[40]= 0.003293
Saving checkpoint... 
Iteration: 333937713, states[0] = -91.223913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341893378, states[0] = -91.127651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349835954, states[0] = -90.881712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357866645, states[0] = -91.036279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366970095, states[0] = -91.264924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375094595, states[0] = -6.702085, states[40]= 0.003234
Saving checkpoint... 
Iteration: 383163567, states[0] = -66.390041, states[40]= 0.000004
Saving checkpoint... 
Iteration: 391067868, states[0] = 10.130118, states[40]= 0.003749
Saving checkpoint... 
Iteration: 399099136, states[0] = -10.971645, states[40]= 0.002335
Saving checkpoint... 
Iteration: 408198984, states[0] = -80.434148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416373228, states[0] = -91.061470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424538723, states[0] = 21.924018, states[40]= 0.001691
Saving checkpoint... 
Iteration: 432746446, states[0] = -88.771390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441878307, states[0] = -91.079570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450033773, states[0] = 23.630568, states[40]= 0.001466
Saving checkpoint... 
Iteration: 458114813, states[0] = -26.558985, states[40]= 0.001036
Saving checkpoint... 
Iteration: 466205343, states[0] = -82.184413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474167728, states[0] = -68.537132, states[40]= 0.000003
Saving checkpoint... 
Iteration: 483298921, states[0] = -90.550226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491314416, states[0] = -90.718492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499485166, states[0] = -91.277468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507330461, states[0] = -90.844989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516269107, states[0] = -89.932746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524433881, states[0] = -91.216665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532348205, states[0] = -90.950656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540476910, states[0] = -91.270434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548466382, states[0] = -91.260232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557404978, states[0] = -91.157335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565353062, states[0] = -90.974932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573296623, states[0] = -90.519084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581156288, states[0] = -62.153084, states[40]= 0.000009
Saving checkpoint... 
Iteration: 589930249, states[0] = -91.210098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597861579, states[0] = -91.013851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605788865, states[0] = -90.400254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613828333, states[0] = -90.829651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621751478, states[0] = -89.120418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630741854, states[0] = -88.386826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638919235, states[0] = -91.188943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646950017, states[0] = -91.240298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655061487, states[0] = 13.001787, states[40]= 0.003284
Saving checkpoint... 
Iteration: 663122747, states[0] = -34.143553, states[40]= 0.000632
Saving checkpoint... 
Iteration: 672455887, states[0] = -91.247698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680578861, states[0] = 4.465679, states[40]= 0.004291
Saving checkpoint... 
Iteration: 688619327, states[0] = -30.892651, states[40]= 0.000834
Saving checkpoint... 
Iteration: 696542417, states[0] = 20.582046, states[40]= 0.001897
Saving checkpoint... 
Iteration: 705482423, states[0] = -91.274290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713383474, states[0] = -91.095569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721579308, states[0] = 4.209558, states[40]= 0.004301
Saving checkpoint... 
Iteration: 730023895, states[0] = 26.454175, states[40]= 0.001509
Saving checkpoint... 
Iteration: 737858692, states[0] = -91.000406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746105802, states[0] = -17.666001, states[40]= 0.001352
Saving checkpoint... 
Iteration: 754612842, states[0] = -24.646216, states[40]= 0.001083
Saving checkpoint... 
Iteration: 762735281, states[0] = -87.712258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770775021, states[0] = -90.104954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778557046, states[0] = 14.878187, states[40]= 0.002938
Saving checkpoint... 
Iteration: 787444503, states[0] = -91.231933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795438493, states[0] = -91.222821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803711424, states[0] = -83.666363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812023688, states[0] = 26.500638, states[40]= 0.001533
Saving checkpoint... 
Iteration: 821026779, states[0] = 25.742672, states[40]= 0.001342
Saving checkpoint... 
Iteration: 829209860, states[0] = -83.302277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837449199, states[0] = -91.238260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845685421, states[0] = -76.013112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853888664, states[0] = -91.111175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863201673, states[0] = -81.195793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871328847, states[0] = -90.831955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879520377, states[0] = 27.138839, states[40]= 0.002358
Saving checkpoint... 
Iteration: 887591414, states[0] = -3.995401, states[40]= 0.003750
Saving checkpoint... 
Iteration: 897001491, states[0] = 45.137909, states[40]= 0.359728
Saving checkpoint... 
Iteration: 905011629, states[0] = 27.569202, states[40]= 0.027494
Saving checkpoint... 
Iteration: 913132674, states[0] = -43.420076, states[40]= 0.000204
Saving checkpoint... 
Iteration: 921153920, states[0] = -60.624152, states[40]= 0.000013
Saving checkpoint... 
Iteration: 929313664, states[0] = -90.709288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938565676, states[0] = 11.144735, states[40]= 0.003596
Saving checkpoint... 
Iteration: 946581967, states[0] = 2.631512, states[40]= 0.004327
Saving checkpoint... 
Iteration: 954523104, states[0] = 26.627820, states[40]= 0.001612
Saving checkpoint... 
Iteration: 962526171, states[0] = 25.902399, states[40]= 0.001357
Saving checkpoint... 
Iteration: 971517090, states[0] = 27.539538, states[40]= 0.005071
Saving checkpoint... 
Iteration: 979739765, states[0] = -88.187256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987872403, states[0] = -91.055533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995834619, states[0] = -90.869955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003885886, states[0] = -91.101837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013005719, states[0] = 28.736945, states[40]= 0.198381
Saving checkpoint... 
Iteration: 1021141740, states[0] = -51.462882, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1029077738, states[0] = 5.099481, states[40]= 0.004261
Saving checkpoint... 
Iteration: 1037197042, states[0] = -79.855158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045276633, states[0] = -90.144856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053982850, states[0] = -91.272920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061991839, states[0] = -91.279553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070125630, states[0] = -36.860709, states[40]= 0.000472
Saving checkpoint... 
Iteration: 1078272888, states[0] = -90.044619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087434180, states[0] = -91.214387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095646127, states[0] = -55.016418, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1103631667, states[0] = -42.490644, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1111751113, states[0] = -89.093941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119688967, states[0] = -77.260279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128756925, states[0] = -89.427760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136849760, states[0] = -90.955616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144817999, states[0] = -90.746714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152877595, states[0] = -91.073538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162004597, states[0] = 30.535119, states[40]= 0.286055
Saving checkpoint... 
Iteration: 1170156965, states[0] = -62.572769, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1177956907, states[0] = -91.246452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186019250, states[0] = 27.305871, states[40]= 0.002963
Saving checkpoint... 
Iteration: 1193981314, states[0] = -91.270984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202735547, states[0] = -87.739449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210965161, states[0] = -91.255680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219012473, states[0] = 27.612561, states[40]= 0.020837
Saving checkpoint... 
Iteration: 1227153052, states[0] = -60.042959, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1236247429, states[0] = -88.839688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244318979, states[0] = -90.754473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252412603, states[0] = -91.171757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260525733, states[0] = 26.014749, states[40]= 0.001374
Saving checkpoint... 
Iteration: 1268472267, states[0] = -91.262581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277413417, states[0] = -91.173438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285475092, states[0] = -91.265135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293466849, states[0] = -91.257054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301496603, states[0] = -91.281497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309955433, states[0] = -91.244000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318083895, states[0] = 1.422411, states[40]= 0.004307
Saving checkpoint... 
Iteration: 1326164615, states[0] = -66.943558, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1334083386, states[0] = 1.747758, states[40]= 0.004316
Saving checkpoint... 
Iteration: 1342148747, states[0] = -57.002406, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1351437693, states[0] = -91.218813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359425596, states[0] = -91.197837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367626764, states[0] = -37.923720, states[40]= 0.000417
Saving checkpoint... 
Iteration: 1375677460, states[0] = -72.930708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383838491, states[0] = -90.891979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392884010, states[0] = -91.093921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400934128, states[0] = -91.212754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408901368, states[0] = -91.144020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416770281, states[0] = -89.964842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425728488, states[0] = -86.829778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433793506, states[0] = -90.469770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441670873, states[0] = -70.041886, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1449780078, states[0] = -90.224056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457844794, states[0] = -90.927768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467056018, states[0] = 15.301819, states[40]= 0.002857
Saving checkpoint... 
Iteration: 1475093202, states[0] = -5.481425, states[40]= 0.003480
Saving checkpoint... 
Iteration: 1483049767, states[0] = 17.793601, states[40]= 0.002385
Saving checkpoint... 
Iteration: 1490995913, states[0] = -91.280130, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.158456
 - CaMKt in component CaMK (millimolar): 0.012449
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.632470
 - nass in component intracellular_ions (millimolar): 6.632564
 - ki in component intracellular_ions (millimolar): 145.252350
 - kss in component intracellular_ions (millimolar): 145.252329
 - cansr in component intracellular_ions (millimolar): 1.644733
 - cajsr in component intracellular_ions (millimolar): 1.602315
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005278
 - hf in component INa (dimensionless): 0.798565
 - hs in component INa (dimensionless): 0.798527
 - j in component INa (dimensionless): 0.798255
 - hsp in component INa (dimensionless): 0.588513
 - jp in component INa (dimensionless): 0.798040
 - mL in component INaL (dimensionless): 0.000101
 - hL in component INaL (dimensionless): 0.585296
 - hLp in component INaL (dimensionless): 0.309096
 - a in component Ito (dimensionless): 0.000802
 - iF in component Ito (dimensionless): 0.999749
 - iS in component Ito (dimensionless): 0.574713
 - ap in component Ito (dimensionless): 0.000409
 - iFp in component Ito (dimensionless): 0.999749
 - iSp in component Ito (dimensionless): 0.629767
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915650
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999835
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002951
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.440418
 - xs1 in component IKs (dimensionless): 0.270217
 - xs2 in component IKs (dimensionless): 0.000134
 - xk1 in component IK1 (dimensionless): 0.998162
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:30:17 (20096): called boinc_finish(0)

</stderr_txt>
]]>


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