𝕏

Task 55698456

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_591_0
Workunit 26450043
Created 1 Jul 2024, 16:15:06 UTC
Sent 2 Jul 2024, 13:02:24 UTC
Report deadline 5 Jul 2024, 13:02:24 UTC
Received 2 Jul 2024, 23:07:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 44 min 30 sec
CPU time 1 hours 36 min 58 sec
Validate state Valid
Credit 41.50
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.36 MB
Peak swap size 4.13 GB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_591.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_591_0_r1094909748_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_591_0_r1094909748_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.910105
     * GNaL_b in INaL: 0.005781
     * Gto_b in Ito: 0.084142
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032312
     * GKs_b in IKs: 0.001901
     * GK1_b in IK1: 0.166385
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.455118
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032325
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12437500, states[0] = -86.736900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24836272, states[0] = -86.687221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38284647, states[0] = -86.503522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51509294, states[0] = -86.589030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64167656, states[0] = -62.747822, states[40]= 0.000003
Saving checkpoint... 
Iteration: 77382444, states[0] = -86.551983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89835342, states[0] = -86.536509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102394417, states[0] = -86.497030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115874262, states[0] = -86.522378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129187647, states[0] = -86.526351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140916513, states[0] = -86.528592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153996395, states[0] = -86.512344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166579976, states[0] = -86.520884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178954924, states[0] = -86.523035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191966175, states[0] = -86.508920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204225035, states[0] = -86.304907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216580326, states[0] = -86.517895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230152360, states[0] = -44.819854, states[40]= 0.000061
Saving checkpoint... 
Iteration: 241273401, states[0] = -86.514697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254593615, states[0] = -86.518093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267117841, states[0] = -86.517108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279617823, states[0] = -86.509668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292849457, states[0] = -86.521636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305762343, states[0] = -86.508165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316882269, states[0] = -86.521098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329835102, states[0] = -86.507505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342059225, states[0] = 13.634817, states[40]= 0.004214
Saving checkpoint... 
Iteration: 354556300, states[0] = -86.514495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367320281, states[0] = -86.513234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379794771, states[0] = -86.507753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391699434, states[0] = -86.508573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404759449, states[0] = -86.522033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417008639, states[0] = -86.518778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430147431, states[0] = -40.410449, states[40]= 0.000122
Saving checkpoint... 
Iteration: 443132375, states[0] = -86.516421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455228857, states[0] = -86.514685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467745407, states[0] = -86.508129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480634723, states[0] = -86.519781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493388928, states[0] = -86.512152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505194477, states[0] = -86.515274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517184003, states[0] = -86.515458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530281395, states[0] = -86.387021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543034572, states[0] = -86.518251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555588266, states[0] = -86.509641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568145471, states[0] = -38.703674, states[40]= 0.000157
Saving checkpoint... 
Iteration: 580618255, states[0] = -86.518987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593065852, states[0] = -86.517644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605697798, states[0] = -86.508528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618353529, states[0] = -86.454121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631707561, states[0] = -86.508432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644187721, states[0] = -82.504020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654069636, states[0] = 10.433786, states[40]= 0.004212
Saving checkpoint... 
Iteration: 664573379, states[0] = -86.515962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674732219, states[0] = -86.521883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686284396, states[0] = -86.390730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697018228, states[0] = -86.518532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706911724, states[0] = -86.520448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719372848, states[0] = -86.512339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731101204, states[0] = -86.516945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742477583, states[0] = -86.502610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754104092, states[0] = -4.901567, states[40]= 0.002940
Saving checkpoint... 
Iteration: 765792611, states[0] = -86.507670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777570978, states[0] = -86.509789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789180972, states[0] = -86.515459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801031350, states[0] = -86.518262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813040511, states[0] = -86.518085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825649127, states[0] = -86.508954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837559654, states[0] = -86.509904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849635077, states[0] = -86.509091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861616511, states[0] = -86.509281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874028178, states[0] = 21.009288, states[40]= 0.005141
Saving checkpoint... 
Iteration: 886584098, states[0] = -86.516775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898246685, states[0] = -86.337246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910141915, states[0] = -35.637376, states[40]= 0.000245
Saving checkpoint... 
Iteration: 921944245, states[0] = -86.506529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932663115, states[0] = -86.520695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944539497, states[0] = -86.512505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955979834, states[0] = -86.506293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967072001, states[0] = -86.517454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977674240, states[0] = -86.508679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989030003, states[0] = -86.518251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001761947, states[0] = -86.507880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013295042, states[0] = -86.513473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025454220, states[0] = -86.511154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037577245, states[0] = -86.509669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049743255, states[0] = -86.508032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061279345, states[0] = -86.513718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073626253, states[0] = -86.509139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084664214, states[0] = -86.520697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095296662, states[0] = -86.513431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106905431, states[0] = -86.520473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119521539, states[0] = -86.510293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130887805, states[0] = -86.520743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142524495, states[0] = -86.510560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154471673, states[0] = -86.501250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166018001, states[0] = 21.979616, states[40]= 0.009650
Saving checkpoint... 
Iteration: 1178387894, states[0] = -86.473297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189173027, states[0] = -86.515525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201221445, states[0] = -86.514665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213115987, states[0] = -86.516573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224669498, states[0] = -86.520814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236466859, states[0] = -86.500139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248265546, states[0] = -86.365581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259932472, states[0] = -86.506541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272301059, states[0] = -86.409714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283895646, states[0] = -86.506789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295890692, states[0] = -86.506822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307782737, states[0] = -86.507646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320000593, states[0] = 34.632027, states[40]= 0.004816
Saving checkpoint... 
Iteration: 1331388412, states[0] = -86.511996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343094435, states[0] = -86.516955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355764435, states[0] = -86.507790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367597447, states[0] = -86.509385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379731519, states[0] = -86.508071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391012479, states[0] = -86.518507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402781176, states[0] = -86.521787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415681849, states[0] = -86.508521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427434386, states[0] = -86.511340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439342663, states[0] = -86.512649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450447210, states[0] = -86.495096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462770463, states[0] = -86.521806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474462954, states[0] = -86.499169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486423228, states[0] = -86.487642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497937835, states[0] = -86.506460, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.382033
 - CaMKt in component CaMK (millimolar): 0.000891
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.036425
 - nass in component intracellular_ions (millimolar): 6.036469
 - ki in component intracellular_ions (millimolar): 145.959353
 - kss in component intracellular_ions (millimolar): 145.959342
 - cansr in component intracellular_ions (millimolar): 1.250482
 - cajsr in component intracellular_ions (millimolar): 1.250626
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008536
 - hf in component INa (dimensionless): 0.643943
 - hs in component INa (dimensionless): 0.643943
 - j in component INa (dimensionless): 0.643946
 - hsp in component INa (dimensionless): 0.395033
 - jp in component INa (dimensionless): 0.643948
 - mL in component INaL (dimensionless): 0.000250
 - hL in component INaL (dimensionless): 0.463233
 - hLp in component INaL (dimensionless): 0.273568
 - a in component Ito (dimensionless): 0.001107
 - iF in component Ito (dimensionless): 0.999421
 - iS in component Ito (dimensionless): 0.985533
 - ap in component Ito (dimensionless): 0.000564
 - iFp in component Ito (dimensionless): 0.999421
 - iSp in component Ito (dimensionless): 0.991639
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997484
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001268
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020337
 - xs1 in component IKs (dimensionless): 0.037269
 - xs2 in component IKs (dimensionless): 0.000228
 - xk1 in component IK1 (dimensionless): 0.997130
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:13:44 (21896): called boinc_finish(0)

</stderr_txt>
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