𝕏

Task 55696917

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_5000-conf_890_1
Workunit 26449276
Created 1 Jul 2024, 16:14:29 UTC
Sent 2 Jul 2024, 12:49:29 UTC
Report deadline 5 Jul 2024, 12:49:29 UTC
Received 3 Jul 2024, 1:35:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 5 min 14 sec
CPU time 2 hours 4 min 15 sec
Validate state Valid
Credit 43.76
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.56 MB
Peak swap size 4.10 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_5000-conf_890.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_5000-conf_890_1_r1769319125_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_5000-conf_890_1_r1769319125_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.733337
     * GNaL_b in INaL: 0.006219
     * Gto_b in Ito: 0.083370
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031555
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.163136
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.120711
     * GKb_b in IKb: 0.003815
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030581
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12138087, states[0] = -94.657973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24381463, states[0] = -94.583276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36618177, states[0] = -94.544622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48861256, states[0] = -94.524672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61136086, states[0] = -94.514391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73333081, states[0] = -94.509876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85614003, states[0] = -94.494991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97905450, states[0] = -94.418698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110103233, states[0] = -0.573211, states[40]= 0.004339
Saving checkpoint... 
Iteration: 122320463, states[0] = -94.474542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134518716, states[0] = -94.474858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146655934, states[0] = -94.477168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158797688, states[0] = -94.481632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170988312, states[0] = -94.487035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183171514, states[0] = -94.484912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195393087, states[0] = -94.397623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207652957, states[0] = -37.932774, states[40]= 0.000604
Saving checkpoint... 
Iteration: 219858271, states[0] = -94.468313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232048221, states[0] = -94.470166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244247447, states[0] = -94.472794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256427346, states[0] = -94.476937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268581687, states[0] = -94.483341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280786248, states[0] = -94.487015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293014424, states[0] = -94.459848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305278713, states[0] = -94.217601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317507107, states[0] = 27.143072, states[40]= 0.124103
Saving checkpoint... 
Iteration: 329790224, states[0] = -94.468066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342011229, states[0] = -94.469964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354205010, states[0] = -94.472882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366454513, states[0] = -94.476207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378290552, states[0] = -94.486856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390050029, states[0] = 21.331713, states[40]= 0.002682
Saving checkpoint... 
Iteration: 402063290, states[0] = -94.469495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414367878, states[0] = -94.471133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426617444, states[0] = -94.473868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438788844, states[0] = -94.478946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450981870, states[0] = -94.484999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463238637, states[0] = -94.486021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475456717, states[0] = -94.437889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487733249, states[0] = -94.074401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500039123, states[0] = 24.190622, states[40]= 0.002122
Saving checkpoint... 
Iteration: 512281281, states[0] = -94.467952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524542654, states[0] = -94.469561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536678568, states[0] = -94.473041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548750847, states[0] = -94.479579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560916385, states[0] = -94.486001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573075065, states[0] = -94.472948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585224984, states[0] = -94.036390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597386023, states[0] = -94.467302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609584552, states[0] = -94.469186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621734316, states[0] = -94.472346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633858279, states[0] = -94.477572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646096443, states[0] = -94.482597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658304674, states[0] = -94.486718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670455425, states[0] = -94.437126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682581856, states[0] = 10.246445, states[40]= 0.004423
Saving checkpoint... 
Iteration: 694783193, states[0] = -94.467814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706934413, states[0] = -94.470322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719123382, states[0] = -94.473587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731252602, states[0] = -94.479420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743363650, states[0] = -94.486478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755530006, states[0] = -94.463607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767632839, states[0] = -22.209082, states[40]= 0.001587
Saving checkpoint... 
Iteration: 779825011, states[0] = -94.467512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791993579, states[0] = -94.469765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804139375, states[0] = -94.473329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816259527, states[0] = -94.479229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828474867, states[0] = -94.484863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840642091, states[0] = -94.480879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852831727, states[0] = -94.324469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865016653, states[0] = 27.297309, states[40]= 0.006392
Saving checkpoint... 
Iteration: 877241191, states[0] = -94.467942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889399100, states[0] = -94.470510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901538538, states[0] = -94.474587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913702230, states[0] = -94.480271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925786688, states[0] = -94.486439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937860297, states[0] = -94.362957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949950086, states[0] = -94.466727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962090429, states[0] = -94.468900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974249070, states[0] = -94.471941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986318355, states[0] = -94.478029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998510259, states[0] = -94.484084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010598963, states[0] = -94.476168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022752204, states[0] = -94.139625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034974116, states[0] = -94.466550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047158431, states[0] = -94.468362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059229545, states[0] = -94.472096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071154119, states[0] = -94.481126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083065829, states[0] = -94.471007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095245418, states[0] = -94.117055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107465771, states[0] = -94.466541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119646119, states[0] = -94.468396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131813683, states[0] = -94.471158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143980044, states[0] = -94.475265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156138012, states[0] = -94.481394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168202762, states[0] = -94.484372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180303439, states[0] = -94.273903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192308168, states[0] = -94.467323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204360140, states[0] = -94.470654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216504638, states[0] = -94.474852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228745914, states[0] = -94.479203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240877863, states[0] = -94.486004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253115103, states[0] = -94.477957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265278106, states[0] = -94.215274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277442711, states[0] = -94.466538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289576670, states[0] = -94.468774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301730627, states[0] = -94.471916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313885706, states[0] = -94.476638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326083264, states[0] = -94.482397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338258166, states[0] = -94.485812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350448729, states[0] = -94.433286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362622684, states[0] = -14.154474, states[40]= 0.001798
Saving checkpoint... 
Iteration: 1374819677, states[0] = -94.467131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386950958, states[0] = -94.469709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399110479, states[0] = -94.473281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411153870, states[0] = -94.480896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423428963, states[0] = -94.485220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435592563, states[0] = -94.475009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447764236, states[0] = -94.176626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460014323, states[0] = 27.188998, states[40]= 0.012223
Saving checkpoint... 
Iteration: 1472233325, states[0] = -94.467580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484480983, states[0] = -94.469389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496629483, states[0] = -94.472973, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.342079
 - CaMKt in component CaMK (millimolar): 0.001123
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.283489
 - nass in component intracellular_ions (millimolar): 6.283575
 - ki in component intracellular_ions (millimolar): 145.642303
 - kss in component intracellular_ions (millimolar): 145.642292
 - cansr in component intracellular_ions (millimolar): 1.564315
 - cajsr in component intracellular_ions (millimolar): 1.564343
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003829
 - hf in component INa (dimensionless): 0.869942
 - hs in component INa (dimensionless): 0.869942
 - j in component INa (dimensionless): 0.869943
 - hsp in component INa (dimensionless): 0.707178
 - jp in component INa (dimensionless): 0.869944
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714162
 - hLp in component INaL (dimensionless): 0.521836
 - a in component Ito (dimensionless): 0.000647
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997745
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999252
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998845
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002979
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001801
 - xs1 in component IKs (dimensionless): 0.023049
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997480
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:34:05 (60751): called boinc_finish(0)

</stderr_txt>
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