𝕏

Task 55696369

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_589_0
Workunit 26449003
Created 1 Jul 2024, 16:14:13 UTC
Sent 2 Jul 2024, 12:42:53 UTC
Report deadline 5 Jul 2024, 22:18:53 UTC
Received 2 Jul 2024, 15:52:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241714
Run time 1 hours 48 min 48 sec
CPU time 1 hours 48 min 47 sec
Validate state Valid
Credit 62.86
Device peak FLOPS 4.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.31 MB
Peak swap size 1.43 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_589.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_589_0_r384978677_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_589_0_r384978677_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.896831
     * GNaL_b in INaL: 0.006174
     * Gto_b in Ito: 0.080985
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031314
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167482
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.619769
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031300
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12952784, states[0] = -95.142907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25698825, states[0] = -94.924013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38515674, states[0] = 22.289898, states[40]= 0.016643
Saving checkpoint... 
Iteration: 51341977, states[0] = -95.052218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64261167, states[0] = -94.983220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77154081, states[0] = -78.421786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90113249, states[0] = -30.877300, states[40]= 0.000437
Saving checkpoint... 
Iteration: 102983866, states[0] = -95.074511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115838744, states[0] = -95.032036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128617330, states[0] = -34.443604, states[40]= 0.000286
Saving checkpoint... 
Iteration: 141284577, states[0] = -94.993253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154161074, states[0] = -89.000613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166963638, states[0] = -95.067561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179525656, states[0] = 20.397200, states[40]= 0.007066
Saving checkpoint... 
Iteration: 192411118, states[0] = -95.056264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205272844, states[0] = -94.980864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218032099, states[0] = 18.518223, states[40]= 0.005926
Saving checkpoint... 
Iteration: 230821959, states[0] = -95.019410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243487178, states[0] = -95.070278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256126945, states[0] = -43.765636, states[40]= 0.000076
Saving checkpoint... 
Iteration: 269099653, states[0] = -17.751459, states[40]= 0.001154
Saving checkpoint... 
Iteration: 281860974, states[0] = -95.039129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294489479, states[0] = -95.070481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307372328, states[0] = -95.043614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320192471, states[0] = -94.858679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333212840, states[0] = -94.898280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345946379, states[0] = -95.063718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358666237, states[0] = -93.353318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371480375, states[0] = -95.069215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384353174, states[0] = -95.035648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397099553, states[0] = -17.656115, states[40]= 0.001163
Saving checkpoint... 
Iteration: 410004850, states[0] = 29.609237, states[40]= 0.146963
Saving checkpoint... 
Iteration: 422946095, states[0] = -95.063614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435693665, states[0] = -94.861126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448782715, states[0] = -94.989857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461826242, states[0] = -95.021716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474765640, states[0] = -94.972990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487910598, states[0] = -95.055603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500993368, states[0] = -95.070819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513753193, states[0] = -94.958692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526788693, states[0] = -94.995050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539522204, states[0] = 21.258777, states[40]= 0.008395
Saving checkpoint... 
Iteration: 552406321, states[0] = -95.054414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564863682, states[0] = -95.040051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577665114, states[0] = -92.775228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590552912, states[0] = 10.963352, states[40]= 0.004993
Saving checkpoint... 
Iteration: 603309979, states[0] = -95.011302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615900452, states[0] = -95.052721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628657158, states[0] = -82.476173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641655421, states[0] = -79.365876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654439657, states[0] = -95.062213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667302492, states[0] = -95.005921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680179869, states[0] = -94.814161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692994724, states[0] = -95.070866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705984792, states[0] = -95.069604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718694472, states[0] = -94.862633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731433082, states[0] = -95.060800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744259494, states[0] = -94.966002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757157423, states[0] = -82.950246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770024679, states[0] = 20.657120, states[40]= 0.007360
Saving checkpoint... 
Iteration: 782722128, states[0] = -94.914038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795435182, states[0] = -95.061206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808241081, states[0] = -94.942771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821338804, states[0] = -95.028420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834299113, states[0] = -95.003273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847278823, states[0] = -94.986024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860069322, states[0] = 3.915728, states[40]= 0.004667
Saving checkpoint... 
Iteration: 872992744, states[0] = -95.070514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885633270, states[0] = -50.447526, states[40]= 0.000027
Saving checkpoint... 
Iteration: 898334831, states[0] = -95.026273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911088620, states[0] = -7.955142, states[40]= 0.002768
Saving checkpoint... 
Iteration: 923802484, states[0] = -95.005757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936466064, states[0] = -95.066755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949380861, states[0] = -95.046294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962195205, states[0] = -94.863996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975099321, states[0] = -17.439812, states[40]= 0.001184
Saving checkpoint... 
Iteration: 987994164, states[0] = -95.070617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000637162, states[0] = -54.724577, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1013275446, states[0] = -94.982692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026288334, states[0] = -94.994436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039048488, states[0] = 12.681890, states[40]= 0.005063
Saving checkpoint... 
Iteration: 1051671420, states[0] = -94.529462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064513701, states[0] = 22.914094, states[40]= 0.023808
Saving checkpoint... 
Iteration: 1077690062, states[0] = -94.852903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090678576, states[0] = -94.801538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103659683, states[0] = -86.817900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116607767, states[0] = -25.309283, states[40]= 0.000707
Saving checkpoint... 
Iteration: 1129382517, states[0] = -95.046754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142267949, states[0] = -94.975032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154995058, states[0] = -95.070622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167766239, states[0] = -94.973204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180575432, states[0] = 0.799943, states[40]= 0.004364
Saving checkpoint... 
Iteration: 1193391076, states[0] = -95.049530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206086102, states[0] = -6.000091, states[40]= 0.003189
Saving checkpoint... 
Iteration: 1219152782, states[0] = -74.864208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231928328, states[0] = -95.059453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244550703, states[0] = 11.827954, states[40]= 0.005025
Saving checkpoint... 
Iteration: 1257372546, states[0] = -95.043099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270126762, states[0] = -43.573187, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1282785493, states[0] = -94.991817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295687225, states[0] = -94.845896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308541841, states[0] = 15.172166, states[40]= 0.005247
Saving checkpoint... 
Iteration: 1321445742, states[0] = -95.062994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334222498, states[0] = -94.914309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346803629, states[0] = -95.006339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359624786, states[0] = -41.567069, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1372655989, states[0] = -80.376052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385399471, states[0] = -95.051962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398391495, states[0] = -95.049536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411415529, states[0] = -95.056304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424349800, states[0] = -95.033457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437195451, states[0] = -94.864207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449892619, states[0] = -95.049856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462713095, states[0] = -94.898032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475487270, states[0] = -95.069455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488079042, states[0] = -1.264298, states[40]= 0.004080
Saving checkpoint... 
Iteration: 1500860696, states[0] = -95.241442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513465912, states[0] = -95.272223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526326952, states[0] = -95.241534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539136531, states[0] = -84.836215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551765082, states[0] = -95.136632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564342645, states[0] = -93.268106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577216187, states[0] = -54.902368, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1589912511, states[0] = -95.246319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602426809, states[0] = -69.584330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1615449972, states[0] = -95.297767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628229026, states[0] = -73.326630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1640988577, states[0] = -95.332135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653715233, states[0] = -54.124140, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1666156068, states[0] = -95.305403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678948622, states[0] = -94.890664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691971038, states[0] = -95.319256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704847165, states[0] = -95.296359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717834951, states[0] = 15.412558, states[40]= 0.006567
Saving checkpoint... 
Iteration: 1730463664, states[0] = -0.209453, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1743214020, states[0] = -95.252668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755949057, states[0] = 8.461455, states[40]= 0.005691
Saving checkpoint... 
Iteration: 1768409058, states[0] = -95.244617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781119356, states[0] = 21.509022, states[40]= 0.011911
Saving checkpoint... 
Iteration: 1793777731, states[0] = -12.431852, states[40]= 0.002122
Saving checkpoint... 
Iteration: 1806271323, states[0] = -95.025810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819048066, states[0] = 12.184935, states[40]= 0.005092
Saving checkpoint... 
Iteration: 1831762544, states[0] = -94.995072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844581860, states[0] = -3.733129, states[40]= 0.003669
Saving checkpoint... 
Iteration: 1857115794, states[0] = -33.655389, states[40]= 0.000316
Saving checkpoint... 
Iteration: 1869584616, states[0] = -5.283317, states[40]= 0.003348
Saving checkpoint... 
Iteration: 1882369867, states[0] = -95.047579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895202124, states[0] = -94.881340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907835741, states[0] = -95.028910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920667695, states[0] = -93.924583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933387570, states[0] = -95.049229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946169633, states[0] = -94.318339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958804964, states[0] = -95.007519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971433481, states[0] = -95.060508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984013509, states[0] = 22.947244, states[40]= 0.024709
Saving checkpoint... 
Iteration: 1996744802, states[0] = -94.947238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009302408, states[0] = -95.005124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022415237, states[0] = -95.055900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035181281, states[0] = -94.823101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047877942, states[0] = -95.044582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060574431, states[0] = 1.338591, states[40]= 0.004426
Saving checkpoint... 
Iteration: 2073183266, states[0] = -94.832718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086039955, states[0] = 15.854202, states[40]= 0.005329
Saving checkpoint... 
Iteration: 2098890829, states[0] = -95.048851, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.946452
 - CaMKt in component CaMK (millimolar): 0.006976
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.587209
 - nass in component intracellular_ions (millimolar): 6.587269
 - ki in component intracellular_ions (millimolar): 145.390733
 - kss in component intracellular_ions (millimolar): 145.390714
 - cansr in component intracellular_ions (millimolar): 1.311382
 - cajsr in component intracellular_ions (millimolar): 1.273266
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003602
 - hf in component INa (dimensionless): 0.880772
 - hs in component INa (dimensionless): 0.880768
 - j in component INa (dimensionless): 0.880740
 - hsp in component INa (dimensionless): 0.727287
 - jp in component INa (dimensionless): 0.880721
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710769
 - hLp in component INaL (dimensionless): 0.452378
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.619794
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.694290
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933212
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999879
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336315
 - xs1 in component IKs (dimensionless): 0.245053
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:46:26 (4204): called boinc_finish(0)

</stderr_txt>
]]>


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