𝕏

Task 55691577

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_385_0
Workunit 26446611
Created 1 Jul 2024, 16:11:56 UTC
Sent 2 Jul 2024, 12:14:48 UTC
Report deadline 5 Jul 2024, 12:14:48 UTC
Received 3 Jul 2024, 17:23:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 2 hours 43 min 12 sec
CPU time 2 hours 16 min 18 sec
Validate state Valid
Credit 42.12
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 1.38 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_385.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_385_0_r454230012_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_385_0_r454230012_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.943955
     * GNaL_b in INaL: 0.005768
     * Gto_b in Ito: 0.088075
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031494
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.163085
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.651507
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036812
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10863722, states[0] = -94.804657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21176803, states[0] = -80.885733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31521429, states[0] = -94.700714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42592893, states[0] = -94.694813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53211769, states[0] = -94.240845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63331959, states[0] = -94.547951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74086067, states[0] = 5.174883, states[40]= 0.004473
Saving checkpoint... 
Iteration: 84372135, states[0] = -94.584764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95501732, states[0] = -94.650884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106135918, states[0] = -32.623124, states[40]= 0.000936
Saving checkpoint... 
Iteration: 116659522, states[0] = -94.669371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126785642, states[0] = -94.670707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136985446, states[0] = -94.666265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146523428, states[0] = -94.650618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157386617, states[0] = -94.588406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167597146, states[0] = -94.661424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178030443, states[0] = 25.028147, states[40]= 0.001664
Saving checkpoint... 
Iteration: 188417152, states[0] = -94.608787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199481145, states[0] = -94.637541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210229770, states[0] = -94.287444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220968516, states[0] = -94.664349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231918806, states[0] = -94.665465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242190303, states[0] = -90.468675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252618621, states[0] = -94.662326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262796523, states[0] = -94.667267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273749247, states[0] = -94.667243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284738803, states[0] = -94.667120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294892610, states[0] = -94.665758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304529854, states[0] = -94.649847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311384173, states[0] = -94.584745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318506344, states[0] = -94.644306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325326297, states[0] = -94.521084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332174567, states[0] = -68.993894, states[40]= 0.000004
Saving checkpoint... 
Iteration: 339221422, states[0] = -94.255392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345719776, states[0] = -94.666707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352289885, states[0] = -94.457548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359248018, states[0] = -94.348959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366181476, states[0] = -78.341008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373294567, states[0] = -94.467042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380086988, states[0] = 5.024273, states[40]= 0.004507
Saving checkpoint... 
Iteration: 386605429, states[0] = -94.660780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392802284, states[0] = -94.666902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399685211, states[0] = -94.665718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405939463, states[0] = -94.664464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412672556, states[0] = -94.665213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419257560, states[0] = -94.377646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426092608, states[0] = 2.001992, states[40]= 0.004474
Saving checkpoint... 
Iteration: 433020605, states[0] = 26.554397, states[40]= 0.002652
Saving checkpoint... 
Iteration: 438210939, states[0] = -94.205227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445474067, states[0] = -94.634203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453058335, states[0] = 16.992437, states[40]= 0.003116
Saving checkpoint... 
Iteration: 460619043, states[0] = -94.661863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468199678, states[0] = -93.890833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475680928, states[0] = -94.665423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483240074, states[0] = -94.322780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490810697, states[0] = -94.666647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498227697, states[0] = -94.278931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505351134, states[0] = -94.552478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513680118, states[0] = -94.665323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521109172, states[0] = -9.520219, states[40]= 0.002612
Saving checkpoint... 
Iteration: 528265827, states[0] = -94.400358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535626002, states[0] = -94.662279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542910374, states[0] = -94.664881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550063001, states[0] = 15.342122, states[40]= 0.003428
Saving checkpoint... 
Iteration: 557505732, states[0] = -94.643683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565223168, states[0] = -94.261735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572716869, states[0] = -94.666225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579919992, states[0] = -94.664596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587360852, states[0] = -94.562783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594616247, states[0] = -94.661378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602028246, states[0] = 25.478362, states[40]= 0.001649
Saving checkpoint... 
Iteration: 609602246, states[0] = -94.660050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615613715, states[0] = -94.661119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621621167, states[0] = -94.661739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628254972, states[0] = -94.369692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635258279, states[0] = -94.379306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642102019, states[0] = -3.968332, states[40]= 0.003783
Saving checkpoint... 
Iteration: 648574812, states[0] = -94.656782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655294678, states[0] = -94.466731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661840922, states[0] = -94.665965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668352006, states[0] = -94.553154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674506079, states[0] = -94.643557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680973934, states[0] = -94.663096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687306923, states[0] = -94.489539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693949599, states[0] = -94.663682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700520661, states[0] = -94.647077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707030415, states[0] = 25.042522, states[40]= 0.001666
Saving checkpoint... 
Iteration: 716626788, states[0] = -94.662004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726869069, states[0] = -94.665381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737386514, states[0] = -94.585828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748150763, states[0] = -45.332585, states[40]= 0.000193
Saving checkpoint... 
Iteration: 758369025, states[0] = -94.570527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768224553, states[0] = -94.266642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778742358, states[0] = -94.666191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789724761, states[0] = -94.665958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800924384, states[0] = -94.664086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811591496, states[0] = -94.658533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821899356, states[0] = -94.664604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832631589, states[0] = -94.662144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842844038, states[0] = -94.665584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852928706, states[0] = -94.663889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863685424, states[0] = -94.664864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873970692, states[0] = -94.662821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882252636, states[0] = -94.362230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891934761, states[0] = -94.663674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902851360, states[0] = -94.665359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912817663, states[0] = -94.665795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922602554, states[0] = -94.659501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932591512, states[0] = -94.658311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942949049, states[0] = -94.663234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953013045, states[0] = 26.593954, states[40]= 0.018094
Saving checkpoint... 
Iteration: 963889645, states[0] = -94.664543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974047690, states[0] = 20.437236, states[40]= 0.002423
Saving checkpoint... 
Iteration: 984472550, states[0] = -94.632663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995900034, states[0] = -94.664267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006721786, states[0] = -94.665508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017384241, states[0] = -94.583465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028233836, states[0] = -94.300168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038742873, states[0] = -94.665714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049574750, states[0] = -94.656032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059717116, states[0] = -94.665328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070606130, states[0] = -94.659578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081186454, states[0] = -85.941312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091959422, states[0] = -94.662702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103080127, states[0] = 8.344625, states[40]= 0.004344
Saving checkpoint... 
Iteration: 1113815706, states[0] = -94.665444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124587354, states[0] = -94.657477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135449835, states[0] = -94.623318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145942764, states[0] = -94.663012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156931479, states[0] = -94.663261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167204363, states[0] = -94.117538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177975599, states[0] = -94.662133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188676085, states[0] = -94.663919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199537361, states[0] = -94.649674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210207099, states[0] = -94.167402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220469413, states[0] = -94.631085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230599483, states[0] = -94.658619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240865972, states[0] = -94.664485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251669859, states[0] = -94.663544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262019438, states[0] = 26.638658, states[40]= 0.003256
Saving checkpoint... 
Iteration: 1272396479, states[0] = -94.592456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282690248, states[0] = -94.664247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292924226, states[0] = -94.663179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304338385, states[0] = -94.535669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314970072, states[0] = -94.662020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325509889, states[0] = -94.643331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336090971, states[0] = 2.916708, states[40]= 0.004504
Saving checkpoint... 
Iteration: 1346799870, states[0] = -94.665151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357630421, states[0] = -94.661088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368413274, states[0] = -94.603605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379060268, states[0] = 16.320939, states[40]= 0.003246
Saving checkpoint... 
Iteration: 1389895234, states[0] = -94.663639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400538352, states[0] = -94.649493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411736902, states[0] = -94.664965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422687315, states[0] = -94.663893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433404857, states[0] = -94.598031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443721696, states[0] = -94.664698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454361997, states[0] = -94.562339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465063942, states[0] = 14.997906, states[40]= 0.003489
Saving checkpoint... 
Iteration: 1475330045, states[0] = -94.524230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485585624, states[0] = -94.656603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496518282, states[0] = -94.645053, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.536840
 - CaMKt in component CaMK (millimolar): 0.004211
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.476232
 - nass in component intracellular_ions (millimolar): 6.476317
 - ki in component intracellular_ions (millimolar): 145.436328
 - kss in component intracellular_ions (millimolar): 145.436313
 - cansr in component intracellular_ions (millimolar): 1.588025
 - cajsr in component intracellular_ions (millimolar): 1.587356
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003754
 - hf in component INa (dimensionless): 0.873521
 - hs in component INa (dimensionless): 0.873522
 - j in component INa (dimensionless): 0.873527
 - hsp in component INa (dimensionless): 0.713767
 - jp in component INa (dimensionless): 0.873530
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719287
 - hLp in component INaL (dimensionless): 0.511089
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891589
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931436
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975400
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002691
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097741
 - xs1 in component IKs (dimensionless): 0.125878
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997431
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:23:27 (368): called boinc_finish(0)

</stderr_txt>
]]>


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