𝕏

Task 55685612

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_279_1
Workunit 26443640
Created 1 Jul 2024, 16:09:17 UTC
Sent 2 Jul 2024, 11:45:54 UTC
Report deadline 5 Jul 2024, 11:45:54 UTC
Received 2 Jul 2024, 23:08:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 5 min 39 sec
CPU time 2 hours 4 min 40 sec
Validate state Valid
Credit 45.03
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.78 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_279.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_279_1_r1160834127_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_279_1_r1160834127_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.574715
     * GNaL_b in INaL: 0.006184
     * Gto_b in Ito: 0.083561
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032275
     * GKs_b in IKs: 0.001951
     * GK1_b in IK1: 0.163343
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.310551
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037579
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12156657, states[0] = -94.183920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24330465, states[0] = -94.177693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36476553, states[0] = -94.189915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48676433, states[0] = -94.207318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60934077, states[0] = -94.222762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73025621, states[0] = -94.173080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85167959, states[0] = -10.792927, states[40]= 0.000633
Saving checkpoint... 
Iteration: 97344299, states[0] = -94.211194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109514254, states[0] = -94.217347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121701046, states[0] = -94.224226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133904346, states[0] = -94.232374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146187750, states[0] = -94.239827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158241160, states[0] = -94.246554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170307674, states[0] = -93.749647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182492315, states[0] = -94.220670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194870086, states[0] = -94.221663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207064939, states[0] = -94.224399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219272804, states[0] = -94.228360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231464169, states[0] = -94.234560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243698215, states[0] = -94.241953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255412502, states[0] = -94.078025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267439507, states[0] = -94.221512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279577962, states[0] = -94.224290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291746934, states[0] = -94.228636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303810848, states[0] = -94.238314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315871785, states[0] = -94.250248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328006694, states[0] = -94.183931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340162998, states[0] = -9.708383, states[40]= 0.000558
Saving checkpoint... 
Iteration: 352388020, states[0] = -94.221238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364562609, states[0] = -94.223832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376639164, states[0] = -94.229929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388809912, states[0] = -94.237675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400909984, states[0] = -94.249082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413033592, states[0] = -94.199673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425132667, states[0] = 4.001130, states[40]= 0.000138
Saving checkpoint... 
Iteration: 436111704, states[0] = -94.243323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446971000, states[0] = -94.224186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459033372, states[0] = -94.231428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471171229, states[0] = -94.241152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483189778, states[0] = -94.242216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495262735, states[0] = -67.244927, states[40]= 0.000037
Saving checkpoint... 
Iteration: 507448251, states[0] = -94.219584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519578552, states[0] = -94.222361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531896721, states[0] = -94.224420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544035466, states[0] = -94.230662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556208553, states[0] = -94.239272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568320741, states[0] = -94.248158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580436383, states[0] = -94.112317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592462889, states[0] = -94.218782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604704246, states[0] = -94.220457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616865140, states[0] = -94.224137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629088618, states[0] = -94.228805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641369379, states[0] = -94.233894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653622099, states[0] = -94.241153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665750250, states[0] = -94.245382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677912451, states[0] = -94.074600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690126513, states[0] = 6.294006, states[40]= 0.000087
Saving checkpoint... 
Iteration: 702323232, states[0] = -94.218710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714532730, states[0] = -94.221198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 726772446, states[0] = -94.224608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738902735, states[0] = -94.232189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751121886, states[0] = -94.240334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763264039, states[0] = -94.245178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775437449, states[0] = -94.112094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787597694, states[0] = 16.897491, states[40]= 0.000007
Saving checkpoint... 
Iteration: 799701080, states[0] = -94.218829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811759649, states[0] = -94.224096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 823864761, states[0] = -94.232472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836023929, states[0] = -94.242634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848118371, states[0] = -94.227158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860322647, states[0] = -93.817282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872488569, states[0] = -94.216268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 884636357, states[0] = -94.218690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896777430, states[0] = -94.223085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908894448, states[0] = -94.230963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921029575, states[0] = -94.241747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933264386, states[0] = -94.243751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 945426698, states[0] = -94.095315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957559743, states[0] = 29.787705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969729149, states[0] = -94.217151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 981902010, states[0] = -94.220530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993991611, states[0] = -94.227841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006139844, states[0] = -94.237607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018239064, states[0] = -94.241787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030376449, states[0] = -93.996167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042483166, states[0] = -94.214852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054571439, states[0] = -94.217893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066703651, states[0] = -94.222888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078731635, states[0] = -94.234136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090966769, states[0] = -94.242034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103280974, states[0] = -94.242882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115560208, states[0] = -94.206324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127781725, states[0] = -92.373324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139814137, states[0] = -94.215059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151975041, states[0] = -94.218153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164141034, states[0] = -94.223220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176293060, states[0] = -94.231487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188288392, states[0] = -94.242363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200392476, states[0] = -94.031722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212492269, states[0] = -94.213361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224664259, states[0] = -94.215543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236838361, states[0] = -94.219261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248933212, states[0] = -94.227087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260906103, states[0] = -94.241863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273020721, states[0] = -94.185016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285138345, states[0] = 1.835876, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1297488454, states[0] = -94.212659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309536033, states[0] = -94.216110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321695459, states[0] = -94.220870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333769997, states[0] = -94.230825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346003481, states[0] = -94.238897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357848698, states[0] = -93.912675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369779973, states[0] = -94.213355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381827413, states[0] = -94.218194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393912782, states[0] = -94.226375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406089788, states[0] = -94.235794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418201553, states[0] = -94.235513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430376694, states[0] = -93.993326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442458858, states[0] = -94.211586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454573165, states[0] = -94.214480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466571314, states[0] = -94.222061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478700095, states[0] = -94.231713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490833745, states[0] = -94.240429, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.086856
 - CaMKt in component CaMK (millimolar): 0.001765
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.746925
 - nass in component intracellular_ions (millimolar): 7.747076
 - ki in component intracellular_ions (millimolar): 144.073458
 - kss in component intracellular_ions (millimolar): 144.073444
 - cansr in component intracellular_ions (millimolar): 1.786206
 - cajsr in component intracellular_ions (millimolar): 1.787672
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003929
 - hf in component INa (dimensionless): 0.865123
 - hs in component INa (dimensionless): 0.865123
 - j in component INa (dimensionless): 0.865124
 - hsp in component INa (dimensionless): 0.698419
 - jp in component INa (dimensionless): 0.865125
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707156
 - hLp in component INaL (dimensionless): 0.513280
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997214
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999038
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998044
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004296
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002426
 - xs1 in component IKs (dimensionless): 0.032517
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997543
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:28:49 (59651): called boinc_finish(0)

</stderr_txt>
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