𝕏

Task 55680824

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET-conf_675_0
Workunit 26441254
Created 1 Jul 2024, 16:07:15 UTC
Sent 2 Jul 2024, 11:18:10 UTC
Report deadline 5 Jul 2024, 14:10:58 UTC
Received 4 Jul 2024, 15:50:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231343
Run time 1 hours 0 min 19 sec
CPU time 51 min 10 sec
Validate state Valid
Credit 50.05
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 5.27 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET-conf_675.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET-conf_675_0_r1756435820_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET-conf_675_0_r1756435820_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.632529
     * GNaL_b in INaL: 0.005788
     * Gto_b in Ito: 0.086658
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031540
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.160889
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.241173
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029927
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6734563, states[0] = -94.768416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16263384, states[0] = -94.747774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23136916, states[0] = -49.231264, states[40]= 0.000095
Saving checkpoint... 
Iteration: 32889459, states[0] = -94.866314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42568157, states[0] = 9.851603, states[40]= 0.004170
Saving checkpoint... 
Iteration: 52397959, states[0] = -94.861720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61818402, states[0] = -94.788781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71490277, states[0] = -94.892694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81071057, states[0] = 8.561832, states[40]= 0.004348
Saving checkpoint... 
Iteration: 90556253, states[0] = 15.229046, states[40]= 0.003258
Saving checkpoint... 
Iteration: 100327053, states[0] = -94.795782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109877075, states[0] = -94.842005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119363509, states[0] = -94.831298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128794235, states[0] = -94.747720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138203941, states[0] = -94.487244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147635214, states[0] = -45.816623, states[40]= 0.000170
Saving checkpoint... 
Iteration: 157131568, states[0] = -42.130049, states[40]= 0.000282
Saving checkpoint... 
Iteration: 166438668, states[0] = -94.873438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175557748, states[0] = 14.638279, states[40]= 0.003388
Saving checkpoint... 
Iteration: 184921884, states[0] = -94.866293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194069388, states[0] = 9.429768, states[40]= 0.004257
Saving checkpoint... 
Iteration: 203110089, states[0] = -21.503807, states[40]= 0.001257
Saving checkpoint... 
Iteration: 212510565, states[0] = 27.674110, states[40]= 0.040702
Saving checkpoint... 
Iteration: 221716389, states[0] = -94.538119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230692073, states[0] = -94.424017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239631817, states[0] = -42.363342, states[40]= 0.000273
Saving checkpoint... 
Iteration: 248763377, states[0] = -94.684123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258148493, states[0] = -59.792767, states[40]= 0.000020
Saving checkpoint... 
Iteration: 267463804, states[0] = -94.881272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276828926, states[0] = -94.795712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286015419, states[0] = 27.636548, states[40]= 0.008675
Saving checkpoint... 
Iteration: 295364108, states[0] = -94.830189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304731152, states[0] = -94.591638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313975005, states[0] = -94.884189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323643653, states[0] = -54.586790, states[40]= 0.000046
Saving checkpoint... 
Iteration: 332760064, states[0] = -94.675711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342065860, states[0] = 11.095095, states[40]= 0.004021
Saving checkpoint... 
Iteration: 351103446, states[0] = -15.002795, states[40]= 0.001742
Saving checkpoint... 
Iteration: 360490932, states[0] = -94.887838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369773864, states[0] = -94.707257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379223731, states[0] = -94.565224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388412923, states[0] = -94.861110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397594999, states[0] = -6.982914, states[40]= 0.003360
Saving checkpoint... 
Iteration: 406783602, states[0] = -94.726744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416247961, states[0] = -94.643314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425473407, states[0] = -94.883319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434592023, states[0] = -4.457463, states[40]= 0.003898
Saving checkpoint... 
Iteration: 443868458, states[0] = -94.833052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452890537, states[0] = -94.848405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462279249, states[0] = -94.718002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471630432, states[0] = -40.984652, states[40]= 0.000327
Saving checkpoint... 
Iteration: 481015006, states[0] = 27.655849, states[40]= 0.009814
Saving checkpoint... 
Iteration: 490403663, states[0] = -94.855893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499755465, states[0] = -94.663353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509246690, states[0] = -94.639318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518918720, states[0] = -94.863376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528355186, states[0] = -94.821642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537754748, states[0] = -94.661324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546849935, states[0] = -94.816752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556215994, states[0] = -94.535168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565687200, states[0] = -94.368823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572632952, states[0] = -43.498355, states[40]= 0.000235
Saving checkpoint... 
Iteration: 581870507, states[0] = -94.834078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591058905, states[0] = 14.155477, states[40]= 0.003484
Saving checkpoint... 
Iteration: 600382189, states[0] = -94.842399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609521445, states[0] = 26.905973, states[40]= 0.002203
Saving checkpoint... 
Iteration: 618644793, states[0] = -55.796239, states[40]= 0.000038
Saving checkpoint... 
Iteration: 627952267, states[0] = -94.876212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634503882, states[0] = 33.908687, states[40]= 0.364993
Saving checkpoint... 
Iteration: 643546235, states[0] = 19.195221, states[40]= 0.002472
Saving checkpoint... 
Iteration: 652773131, states[0] = -94.704550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661980287, states[0] = -94.884140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671040083, states[0] = 21.455226, states[40]= 0.002055
Saving checkpoint... 
Iteration: 679919751, states[0] = -94.863210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689022393, states[0] = 26.723301, states[40]= 0.001962
Saving checkpoint... 
Iteration: 698223953, states[0] = -94.564738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707336085, states[0] = -94.802069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716737267, states[0] = -94.610023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725770739, states[0] = -94.699059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734628268, states[0] = -38.858337, states[40]= 0.000427
Saving checkpoint... 
Iteration: 743746240, states[0] = -94.637075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753043498, states[0] = 20.215730, states[40]= 0.002277
Saving checkpoint... 
Iteration: 762209479, states[0] = -94.507937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771365688, states[0] = -94.829551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780650156, states[0] = -61.630974, states[40]= 0.000015
Saving checkpoint... 
Iteration: 789739612, states[0] = -94.617081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799082900, states[0] = 2.044882, states[40]= 0.004658
Saving checkpoint... 
Iteration: 808148084, states[0] = -59.340715, states[40]= 0.000021
Saving checkpoint... 
Iteration: 817484920, states[0] = -94.884637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826867560, states[0] = -94.830814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836036587, states[0] = 22.677861, states[40]= 0.001855
Saving checkpoint... 
Iteration: 842628532, states[0] = -39.115639, states[40]= 0.000413
Saving checkpoint... 
Iteration: 851811973, states[0] = -94.771597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861115206, states[0] = -26.383822, states[40]= 0.001170
Saving checkpoint... 
Iteration: 870219496, states[0] = -94.547440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879654024, states[0] = -66.114700, states[40]= 0.000007
Saving checkpoint... 
Iteration: 888838073, states[0] = -94.803482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898209162, states[0] = -94.506059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907358502, states[0] = -94.823032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916487483, states[0] = -94.884837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925795114, states[0] = -94.745324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935162992, states[0] = -78.580432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944455981, states[0] = -94.876154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953671591, states[0] = -90.735137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962907831, states[0] = -94.856221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972227815, states[0] = -94.577430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981372074, states[0] = -94.833661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990773995, states[0] = -94.705030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999892368, states[0] = -94.847341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008993325, states[0] = -94.885766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018306078, states[0] = -94.762376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027433753, states[0] = -94.867851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036603232, states[0] = -14.789576, states[40]= 0.001773
Saving checkpoint... 
Iteration: 1045751572, states[0] = -94.650784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054736070, states[0] = -94.604828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064112476, states[0] = -23.786766, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1073292598, states[0] = -94.740431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082429741, states[0] = -94.865990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091687539, states[0] = -94.372105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100834622, states[0] = -94.798884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110123406, states[0] = -34.168954, states[40]= 0.000717
Saving checkpoint... 
Iteration: 1119270292, states[0] = -94.696485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128659899, states[0] = -73.856267, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1138003439, states[0] = 35.773430, states[40]= 0.411319
Saving checkpoint... 
Iteration: 1147630028, states[0] = -40.582832, states[40]= 0.000344
Saving checkpoint... 
Iteration: 1156695671, states[0] = -94.442883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166207915, states[0] = -94.499720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175800225, states[0] = -94.752697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185287926, states[0] = -94.731678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194771948, states[0] = -94.699811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204338497, states[0] = -94.802667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214062787, states[0] = 12.480433, states[40]= 0.003793
Saving checkpoint... 
Iteration: 1223282537, states[0] = -94.721407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232948367, states[0] = -94.872472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242579159, states[0] = 4.291553, states[40]= 0.004663
Saving checkpoint... 
Iteration: 1252048078, states[0] = 18.496366, states[40]= 0.002610
Saving checkpoint... 
Iteration: 1261473155, states[0] = -94.879908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270930730, states[0] = -94.865646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280428367, states[0] = -94.864620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290045090, states[0] = 19.625644, states[40]= 0.002389
Saving checkpoint... 
Iteration: 1299958950, states[0] = -94.875665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309560811, states[0] = 13.342831, states[40]= 0.003638
Saving checkpoint... 
Iteration: 1319061580, states[0] = 13.009659, states[40]= 0.003699
Saving checkpoint... 
Iteration: 1328689719, states[0] = -94.398882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338199384, states[0] = -94.461025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347739690, states[0] = -94.615062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357069054, states[0] = 9.594477, states[40]= 0.004237
Saving checkpoint... 
Iteration: 1366449024, states[0] = -94.872164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375663349, states[0] = -79.145666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385018411, states[0] = 27.376286, states[40]= 0.003886
Saving checkpoint... 
Iteration: 1394481006, states[0] = -94.881387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403709326, states[0] = -94.504688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412969401, states[0] = -94.878280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422401078, states[0] = -94.850736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431655043, states[0] = -67.356407, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1441047973, states[0] = 18.536739, states[40]= 0.002602
Saving checkpoint... 
Iteration: 1450507210, states[0] = 28.233831, states[40]= 0.124758
Saving checkpoint... 
Iteration: 1459754455, states[0] = -94.656827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469411450, states[0] = -94.856047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478722374, states[0] = -94.555771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488104098, states[0] = -15.641133, states[40]= 0.001657
Saving checkpoint... 
Iteration: 1497455396, states[0] = -94.873755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506551160, states[0] = 48.577863, states[40]= 0.152216
Saving checkpoint... 
Iteration: 1513091465, states[0] = -21.491357, states[40]= 0.001637
Saving checkpoint... 
Iteration: 1522170681, states[0] = -94.401949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531139617, states[0] = -94.869161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537529473, states[0] = -94.774845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546471295, states[0] = -94.740238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555579707, states[0] = -94.684510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564634184, states[0] = -94.664959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573692582, states[0] = -94.655432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582924692, states[0] = -94.556500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591892656, states[0] = -94.543834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600858578, states[0] = -94.534402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610021685, states[0] = 26.557364, states[40]= 0.002193
Saving checkpoint... 
Iteration: 1619047410, states[0] = -94.459160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628257816, states[0] = -94.460008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637320674, states[0] = -94.433540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646373452, states[0] = -94.437773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655594443, states[0] = -94.431960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665014190, states[0] = 26.812709, states[40]= 0.012646
Saving checkpoint... 
Iteration: 1674070925, states[0] = -94.423374, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.289876
 - CaMKt in component CaMK (millimolar): 0.001139
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.341728
 - nass in component intracellular_ions (millimolar): 6.341815
 - ki in component intracellular_ions (millimolar): 145.552490
 - kss in component intracellular_ions (millimolar): 145.552479
 - cansr in component intracellular_ions (millimolar): 1.575455
 - cajsr in component intracellular_ions (millimolar): 1.575477
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003849
 - hf in component INa (dimensionless): 0.868968
 - hs in component INa (dimensionless): 0.868968
 - j in component INa (dimensionless): 0.868970
 - hsp in component INa (dimensionless): 0.705399
 - jp in component INa (dimensionless): 0.868970
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712738
 - hLp in component INaL (dimensionless): 0.520103
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997741
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999249
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998861
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003066
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001807
 - xs1 in component IKs (dimensionless): 0.022840
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997493
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:50:33 (9380): called boinc_finish(0)

</stderr_txt>
]]>


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