𝕏

Task 55680040

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474_0
Workunit 26440862
Created 1 Jul 2024, 16:06:54 UTC
Sent 2 Jul 2024, 11:11:24 UTC
Report deadline 5 Jul 2024, 11:11:24 UTC
Received 4 Jul 2024, 9:16:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222140
Run time 1 hours 11 min 49 sec
CPU time 49 min 42 sec
Validate state Valid
Credit 42.72
Device peak FLOPS 3.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.73 MB
Peak swap size 391.76 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474_0_r59621570_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474_0_r59621570_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.464949
     * GNaL_b in INaL: 0.006201
     * Gto_b in Ito: 0.083672
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031997
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.166881
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.147147
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029995
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9756332, states[0] = -94.141819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22049000, states[0] = -94.048293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32179349, states[0] = -93.991315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44896044, states[0] = -93.966145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56540475, states[0] = -93.961109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70036709, states[0] = -93.987450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81050540, states[0] = 25.030906, states[40]= 0.000332
Saving checkpoint... 
Iteration: 93149088, states[0] = -28.573920, states[40]= 0.002625
Saving checkpoint... 
Iteration: 104936983, states[0] = -93.952122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118176261, states[0] = -93.979562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129064221, states[0] = 20.299279, states[40]= 0.000718
Saving checkpoint... 
Iteration: 141247332, states[0] = -93.454898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152789806, states[0] = -93.952240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165418832, states[0] = -93.892914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176651706, states[0] = -93.953038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189610543, states[0] = -93.980734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201215761, states[0] = -87.966144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213684243, states[0] = -93.988110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226820979, states[0] = -93.962369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237014111, states[0] = 31.744207, states[40]= 0.014256
Saving checkpoint... 
Iteration: 248198906, states[0] = -93.956983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259251594, states[0] = -93.976178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272037924, states[0] = -93.958945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285044840, states[0] = 26.859776, states[40]= 0.000238
Saving checkpoint... 
Iteration: 296184193, states[0] = -93.957061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309472553, states[0] = -93.934589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320961843, states[0] = -93.950707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332814470, states[0] = -93.951556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343373775, states[0] = -93.972254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353619105, states[0] = -93.952869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365735874, states[0] = -93.952014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375230267, states[0] = -93.237093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385959488, states[0] = -93.959861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396705703, states[0] = -93.988849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410428253, states[0] = -93.954357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420600609, states[0] = -93.978674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430568117, states[0] = -93.967069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441496402, states[0] = -93.947210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451821808, states[0] = -93.961954, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474_0_r59621570_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_474_0_r59621570_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.464949
     * GNaL_b in INaL: 0.006201
     * Gto_b in Ito: 0.083672
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031997
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.166881
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.147147
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029995
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 451821808
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.961954 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 463123617, states[0] = -93.980262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474490141, states[0] = -93.944060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487213201, states[0] = -93.977074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496127281, states[0] = -93.980075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510525283, states[0] = -93.959211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521318637, states[0] = -93.955226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534224936, states[0] = -92.762436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544005083, states[0] = -93.984454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553812281, states[0] = -93.961952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565138299, states[0] = -93.979566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577144096, states[0] = -93.979339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589775891, states[0] = -93.962541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598289812, states[0] = -93.974377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609005708, states[0] = 30.981556, states[40]= 0.263109
Saving checkpoint... 
Iteration: 620565339, states[0] = -93.952847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633967124, states[0] = -93.985648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644282346, states[0] = -93.955399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655882323, states[0] = -93.960610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667313844, states[0] = -93.973514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678552507, states[0] = -93.967642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689694647, states[0] = -93.951766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701789033, states[0] = -93.951111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714876688, states[0] = -93.988302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725756808, states[0] = -93.951282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737583687, states[0] = -93.952510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748289840, states[0] = -93.974131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759028165, states[0] = 31.044763, states[40]= 0.000199
Saving checkpoint... 
Iteration: 771151092, states[0] = -29.948512, states[40]= 0.002493
Saving checkpoint... 
Iteration: 787984964, states[0] = -93.958830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804430474, states[0] = -93.902709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815648283, states[0] = -93.951893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825677974, states[0] = -93.986674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836342660, states[0] = -93.954469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846939584, states[0] = -93.986228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859111508, states[0] = -93.980052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871747389, states[0] = -93.962605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884778292, states[0] = -93.950880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895615262, states[0] = -93.965246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906466307, states[0] = -93.929737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919004013, states[0] = -93.983879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927606131, states[0] = -93.978754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937826215, states[0] = -93.961081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949230647, states[0] = -93.975729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962080417, states[0] = -93.957239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973124054, states[0] = -93.979411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983132049, states[0] = -93.956553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992710168, states[0] = -93.951161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004047440, states[0] = -93.957606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017018273, states[0] = 32.023504, states[40]= 0.003396
Saving checkpoint... 
Iteration: 1028004376, states[0] = -93.958160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041844744, states[0] = -93.988491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054321304, states[0] = -93.972650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065554829, states[0] = -93.967649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076918607, states[0] = -93.949707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086704031, states[0] = -93.987650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098897337, states[0] = -93.987116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109655250, states[0] = -93.951359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120503167, states[0] = -93.967499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132453614, states[0] = -93.968752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142890640, states[0] = -93.949761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155152558, states[0] = -31.003645, states[40]= 0.002350
Saving checkpoint... 
Iteration: 1164892806, states[0] = -93.987136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176769176, states[0] = -93.988937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189760905, states[0] = -93.961832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200355933, states[0] = -93.804696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212861882, states[0] = -93.987847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224788843, states[0] = -93.988869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238098593, states[0] = -93.956553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250802820, states[0] = -93.950122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262825442, states[0] = -93.949959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272807471, states[0] = -93.988668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283444580, states[0] = -93.952777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293889912, states[0] = -93.987005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303545930, states[0] = -93.966158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316467724, states[0] = -93.952518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328419216, states[0] = -93.952933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338222201, states[0] = -92.127521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346907829, states[0] = -93.949326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358354559, states[0] = -93.953496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369722860, states[0] = -93.962256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379764103, states[0] = -93.950161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392981091, states[0] = -93.983919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403347141, states[0] = -93.953494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414444672, states[0] = -93.968527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426159293, states[0] = -93.977409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437649881, states[0] = -93.983426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450626920, states[0] = -93.964083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460733058, states[0] = -93.950236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472378656, states[0] = -93.953076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484010231, states[0] = -93.957330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493508862, states[0] = -93.951876, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.824541
 - CaMKt in component CaMK (millimolar): 0.001330
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.690006
 - nass in component intracellular_ions (millimolar): 6.690132
 - ki in component intracellular_ions (millimolar): 145.172376
 - kss in component intracellular_ions (millimolar): 145.172367
 - cansr in component intracellular_ions (millimolar): 1.841263
 - cajsr in component intracellular_ions (millimolar): 1.841128
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004034
 - hf in component INa (dimensionless): 0.860014
 - hs in component INa (dimensionless): 0.860014
 - j in component INa (dimensionless): 0.860016
 - hsp in component INa (dimensionless): 0.689264
 - jp in component INa (dimensionless): 0.860016
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699848
 - hLp in component INaL (dimensionless): 0.504675
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999227
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999700
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999513
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005573
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000583
 - xs1 in component IKs (dimensionless): 0.014903
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997606
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:09:42 (77636): called boinc_finish(0)

</stderr_txt>
]]>


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