𝕏

Task 55680037

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274_1
Workunit 26440860
Created 1 Jul 2024, 16:06:54 UTC
Sent 2 Jul 2024, 11:11:24 UTC
Report deadline 5 Jul 2024, 11:11:24 UTC
Received 4 Jul 2024, 11:08:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222140
Run time 1 hours 14 min 8 sec
CPU time 49 min 40 sec
Validate state Valid
Credit 43.90
Device peak FLOPS 3.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.73 MB
Peak swap size 391.76 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274_1_r409981989_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274_1_r409981989_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.761355
     * GNaL_b in INaL: 0.005976
     * Gto_b in Ito: 0.083290
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167794
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.328552
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035194
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9304021, states[0] = -93.936899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22498555, states[0] = -94.039615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33837717, states[0] = -94.023255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44391154, states[0] = -93.976851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56391611, states[0] = -93.969072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68096779, states[0] = -93.968769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80167407, states[0] = -93.966238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89011106, states[0] = -93.967467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99288389, states[0] = -93.644576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111225442, states[0] = -92.860524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122195107, states[0] = -93.964024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132718122, states[0] = -93.995224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142561485, states[0] = -93.973877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152522669, states[0] = -93.960535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164158324, states[0] = -93.963947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174947695, states[0] = -93.992404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185865278, states[0] = -93.957993, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274_1_r409981989_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_274_1_r409981989_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.761355
     * GNaL_b in INaL: 0.005976
     * Gto_b in Ito: 0.083290
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167794
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.328552
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035194
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 185865278
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.957993 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 198579912, states[0] = -93.980481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212005349, states[0] = -93.965647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221829644, states[0] = -93.958079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232465577, states[0] = -93.975705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243803245, states[0] = -93.995472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254934080, states[0] = -93.957408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267201768, states[0] = -70.282521, states[40]= 0.000009
Saving checkpoint... 
Iteration: 278327884, states[0] = -93.961791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289586474, states[0] = -93.972749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299383656, states[0] = -93.961230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312320181, states[0] = -93.738408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324072925, states[0] = 16.918778, states[40]= 0.001294
Saving checkpoint... 
Iteration: 335660197, states[0] = -93.958956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346911880, states[0] = -93.966721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357410808, states[0] = -93.891475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369959595, states[0] = -93.991570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381898591, states[0] = -93.993414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393155420, states[0] = -33.184673, states[40]= 0.002004
Saving checkpoint... 
Iteration: 406403409, states[0] = -93.977028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418578869, states[0] = -93.972708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430271844, states[0] = -93.980822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440651766, states[0] = -93.958849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452278093, states[0] = -93.962004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463738983, states[0] = -93.969412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474916457, states[0] = -93.992758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483453714, states[0] = -93.928404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495141361, states[0] = -23.128538, states[40]= 0.002420
Saving checkpoint... 
Iteration: 505637935, states[0] = -93.971311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518586144, states[0] = -93.959203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535560411, states[0] = -93.972937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545639025, states[0] = -93.958775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556375338, states[0] = -93.977565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568920463, states[0] = -93.966243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578624607, states[0] = -93.958826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590438327, states[0] = -93.960282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601484470, states[0] = -93.974626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613733124, states[0] = -93.969285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625285141, states[0] = -93.980105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634445489, states[0] = -93.975558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644888049, states[0] = -93.957035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656889893, states[0] = -93.957006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666073400, states[0] = 16.737115, states[40]= 0.001324
Saving checkpoint... 
Iteration: 678852729, states[0] = -93.994058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689357136, states[0] = -93.960860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700456791, states[0] = -93.975165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712172403, states[0] = -93.983625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724337091, states[0] = -93.978394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736420488, states[0] = -93.976053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747732549, states[0] = -93.994214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759991035, states[0] = -93.989901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771875178, states[0] = -93.993412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782335879, states[0] = -93.960916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792834786, states[0] = -93.994209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803602723, states[0] = -93.958634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816305688, states[0] = -93.697706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826648008, states[0] = -93.970602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837521317, states[0] = -93.962917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847013575, states[0] = -93.988982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858089598, states[0] = 10.129996, states[40]= 0.002582
Saving checkpoint... 
Iteration: 868113152, states[0] = -93.985430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879850350, states[0] = -93.993791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890175733, states[0] = -93.962417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901694042, states[0] = -93.969572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910735386, states[0] = -93.968778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922870750, states[0] = -93.966452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935185447, states[0] = -93.962237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944681764, states[0] = -93.957851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956368316, states[0] = -93.960337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967511288, states[0] = -93.973402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978075555, states[0] = 15.904551, states[40]= 0.001464
Saving checkpoint... 
Iteration: 988940107, states[0] = -93.965296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002683473, states[0] = -93.991842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011092313, states[0] = 8.927116, states[40]= 0.002822
Saving checkpoint... 
Iteration: 1022335458, states[0] = -93.960544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031188042, states[0] = -93.962058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041636394, states[0] = -93.987850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053331276, states[0] = -93.764104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064084579, states[0] = -93.963228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077184650, states[0] = -55.328340, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1088904731, states[0] = -93.956245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100699581, states[0] = -93.957485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112333273, states[0] = -93.960424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123931160, states[0] = -93.965216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136125041, states[0] = -93.962621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145611560, states[0] = -93.958033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155854670, states[0] = -93.993273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166951133, states[0] = -93.955870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177808385, states[0] = -93.967071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188385636, states[0] = -93.860179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198685578, states[0] = -93.969271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208151659, states[0] = -93.962195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219121375, states[0] = -93.984593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231535754, states[0] = -93.972412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243785902, states[0] = -93.967354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255251544, states[0] = -93.980171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264769379, states[0] = -93.967610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276550847, states[0] = -93.971994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287642346, states[0] = -93.988103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297490847, states[0] = -93.973380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307973372, states[0] = -93.955531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317733001, states[0] = -93.993335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329404483, states[0] = -93.883078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340428283, states[0] = -93.959195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350597839, states[0] = -93.981988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361298787, states[0] = -93.960371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372418741, states[0] = -93.975104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383629196, states[0] = -93.986482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394040235, states[0] = -93.963277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405808421, states[0] = -93.966714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414940088, states[0] = -93.964629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423099733, states[0] = -93.985035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431517181, states[0] = -93.960428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444229804, states[0] = -93.980573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454319201, states[0] = -93.960024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463498100, states[0] = -93.958412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476394132, states[0] = -93.870669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487419652, states[0] = -93.959040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497978902, states[0] = -93.989162, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.831071
 - CaMKt in component CaMK (millimolar): 0.001311
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.687878
 - nass in component intracellular_ions (millimolar): 6.688002
 - ki in component intracellular_ions (millimolar): 145.177528
 - kss in component intracellular_ions (millimolar): 145.177518
 - cansr in component intracellular_ions (millimolar): 1.829026
 - cajsr in component intracellular_ions (millimolar): 1.828900
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004031
 - hf in component INa (dimensionless): 0.860143
 - hs in component INa (dimensionless): 0.860143
 - j in component INa (dimensionless): 0.860145
 - hsp in component INa (dimensionless): 0.689494
 - jp in component INa (dimensionless): 0.860145
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700031
 - hLp in component INaL (dimensionless): 0.504891
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999228
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999700
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999515
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005433
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000582
 - xs1 in component IKs (dimensionless): 0.014862
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997604
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:56:03 (77638): called boinc_finish(0)

</stderr_txt>
]]>


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