𝕏

Task 55680033

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_974_1
Workunit 26440858
Created 1 Jul 2024, 16:06:54 UTC
Sent 2 Jul 2024, 11:11:24 UTC
Report deadline 5 Jul 2024, 11:11:24 UTC
Received 4 Jul 2024, 20:37:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222140
Run time 1 hours 12 min 42 sec
CPU time 49 min 35 sec
Validate state Valid
Credit 43.93
Device peak FLOPS 3.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 391.76 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_974_1_r1164460406_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_974_1_r1164460406_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.903579
     * GNaL_b in INaL: 0.006165
     * Gto_b in Ito: 0.083963
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032231
     * GKs_b in IKs: 0.001882
     * GK1_b in IK1: 0.162094
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.603062
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031683
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17847540, states[0] = -93.812986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33543327, states[0] = -93.925430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46120399, states[0] = -93.908479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57733165, states[0] = -93.261500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69440026, states[0] = -93.879934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81543438, states[0] = -93.887214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92702327, states[0] = -73.252781, states[40]= 0.000006
Saving checkpoint... 
Iteration: 104707786, states[0] = -93.874853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115527334, states[0] = -93.881790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126635410, states[0] = -93.884396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138785834, states[0] = -93.894232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148759493, states[0] = -93.895115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160319768, states[0] = -93.644769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170371620, states[0] = -93.752863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181194094, states[0] = -93.897401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192317578, states[0] = -93.873289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202009300, states[0] = -93.877230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212825864, states[0] = -93.660451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221536317, states[0] = -93.886576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234459027, states[0] = -93.877941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246720872, states[0] = -93.882252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257841525, states[0] = -93.696785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269617300, states[0] = -93.875559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283404832, states[0] = -93.908266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292674752, states[0] = -49.371757, states[40]= 0.000269
Saving checkpoint... 
Iteration: 304288560, states[0] = -93.880786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316173856, states[0] = -93.897888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328999162, states[0] = -93.887341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337248539, states[0] = -93.873780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346828258, states[0] = -93.879956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358852730, states[0] = -93.891570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370116111, states[0] = -4.623893, states[40]= 0.003457
Saving checkpoint... 
Iteration: 381476630, states[0] = -93.887852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392719992, states[0] = -91.724161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403766777, states[0] = -93.894343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415495148, states[0] = -93.867608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428126352, states[0] = -93.903399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441278254, states[0] = -93.893873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452555238, states[0] = 23.141366, states[40]= 0.000457
Saving checkpoint... 
Iteration: 466147210, states[0] = -93.898611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474815473, states[0] = -93.872754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485549759, states[0] = -93.888196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497640783, states[0] = -23.805993, states[40]= 0.002349
Saving checkpoint... 
Iteration: 508852570, states[0] = -93.891282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521191163, states[0] = -93.896839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531449910, states[0] = -93.888308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542955824, states[0] = -93.844040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551644896, states[0] = -93.883304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562961029, states[0] = -93.847611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572687244, states[0] = -59.279418, states[40]= 0.000057
Saving checkpoint... 
Iteration: 581600861, states[0] = -93.884270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589611259, states[0] = -93.875014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601180965, states[0] = -93.897064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610069779, states[0] = 17.862150, states[40]= 0.001009
Saving checkpoint... 
Iteration: 621845135, states[0] = -93.879112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633146500, states[0] = -93.905231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647121637, states[0] = -93.874763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659637586, states[0] = -93.874527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670888948, states[0] = -93.908019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681943503, states[0] = -93.877315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694418041, states[0] = -93.877708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705393899, states[0] = -93.783746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716606328, states[0] = -93.883877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727733179, states[0] = -93.250132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738593647, states[0] = -93.900171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747178333, states[0] = -93.873832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760853854, states[0] = -93.908833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770875756, states[0] = -93.908220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781961776, states[0] = -93.876827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794112950, states[0] = -93.883569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805146247, states[0] = -27.805546, states[40]= 0.002531
Saving checkpoint... 
Iteration: 818289969, states[0] = -93.909815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827460368, states[0] = -93.870588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837536465, states[0] = 28.951978, states[40]= 0.000161
Saving checkpoint... 
Iteration: 850010549, states[0] = 30.884798, states[40]= 0.048959
Saving checkpoint... 
Iteration: 860749355, states[0] = -93.909691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871622312, states[0] = -93.883199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883306991, states[0] = -93.909512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894120523, states[0] = -93.883196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903348693, states[0] = -93.908683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915564303, states[0] = -93.891235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927033861, states[0] = -93.875444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936852081, states[0] = -93.878372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947042599, states[0] = -93.875278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955288064, states[0] = -93.543625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966361696, states[0] = -93.890102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977456692, states[0] = -93.870330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988425988, states[0] = -93.906172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997436850, states[0] = -93.870481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009802823, states[0] = -93.871848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022309305, states[0] = -93.871752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033335039, states[0] = -93.908737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045052202, states[0] = 24.176129, states[40]= 0.000384
Saving checkpoint... 
Iteration: 1056609332, states[0] = -93.883142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069054705, states[0] = -93.884451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081640506, states[0] = -93.882370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093760721, states[0] = -93.893209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105027401, states[0] = 30.944154, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1116463493, states[0] = -93.886783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127448625, states[0] = -93.870114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138878299, states[0] = -93.889248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149920637, states[0] = -93.870342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160976653, states[0] = -93.903965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174010234, states[0] = -93.885396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184616618, states[0] = -93.873780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197811014, states[0] = -93.618256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210447926, states[0] = -93.836907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223596399, states[0] = -93.899117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237509787, states[0] = 30.693136, states[40]= 0.063798
Saving checkpoint... 
Iteration: 1248828629, states[0] = -93.890610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259505705, states[0] = -93.875214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271421701, states[0] = -93.887681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281388245, states[0] = -93.888664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293596756, states[0] = -93.898966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306478465, states[0] = -93.885997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319161830, states[0] = -93.881426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330217973, states[0] = -90.782043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343233431, states[0] = -93.908514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353849419, states[0] = -93.889735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365381559, states[0] = -93.765615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374714381, states[0] = -93.872161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387447353, states[0] = -93.869618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398553615, states[0] = -93.900474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410187149, states[0] = -59.199178, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1421199753, states[0] = -93.894766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432921586, states[0] = -93.813538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443030243, states[0] = -93.880157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454297415, states[0] = -93.878371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468483403, states[0] = -93.903106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477543934, states[0] = 26.833541, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1486704413, states[0] = -93.880175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498239232, states[0] = -93.908316, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.744880
 - CaMKt in component CaMK (millimolar): 0.001589
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.742342
 - nass in component intracellular_ions (millimolar): 6.742467
 - ki in component intracellular_ions (millimolar): 145.118575
 - kss in component intracellular_ions (millimolar): 145.118566
 - cansr in component intracellular_ions (millimolar): 1.837459
 - cajsr in component intracellular_ions (millimolar): 1.837317
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004067
 - hf in component INa (dimensionless): 0.858431
 - hs in component INa (dimensionless): 0.858431
 - j in component INa (dimensionless): 0.858434
 - hsp in component INa (dimensionless): 0.686455
 - jp in component INa (dimensionless): 0.858435
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697621
 - hLp in component INaL (dimensionless): 0.501966
 - a in component Ito (dimensionless): 0.000674
 - iF in component Ito (dimensionless): 0.999840
 - iS in component Ito (dimensionless): 0.997544
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999840
 - iSp in component Ito (dimensionless): 0.999146
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998691
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005453
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002212
 - xs1 in component IKs (dimensionless): 0.024565
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997625
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:37:00 (79575): called boinc_finish(0)

</stderr_txt>
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