𝕏

Task 55679945

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_10000-conf_674_1
Workunit 26440814
Created 1 Jul 2024, 16:06:49 UTC
Sent 2 Jul 2024, 11:11:23 UTC
Report deadline 5 Jul 2024, 11:11:23 UTC
Received 2 Jul 2024, 20:38:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227663
Run time 3 hours 19 min 21 sec
CPU time 2 hours 6 min 34 sec
Validate state Valid
Credit 46.51
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.40 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_10000-conf_674.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_10000-conf_674_1_r1003795040_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_10000-conf_674_1_r1003795040_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.455627
     * GNaL_b in INaL: 0.006040
     * Gto_b in Ito: 0.087449
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031691
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.161241
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.417253
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031455
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 21212895, states[0] = -93.956591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45808166, states[0] = -93.898763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69974015, states[0] = -93.839960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91968070, states[0] = -93.850011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106520656, states[0] = -93.857444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121961869, states[0] = -93.848233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136460429, states[0] = -93.857848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148194003, states[0] = -93.837479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159611334, states[0] = -93.833738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170751520, states[0] = -93.878162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181373521, states[0] = -93.859665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190860724, states[0] = -93.877169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204874392, states[0] = -93.833017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217473881, states[0] = -93.841246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228457135, states[0] = -93.835874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237943358, states[0] = -93.838028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245603663, states[0] = -93.866269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256170407, states[0] = -93.866085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266749513, states[0] = -93.850406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277523496, states[0] = -93.840704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288845879, states[0] = -93.834640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299955655, states[0] = -93.832698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311059117, states[0] = -93.870160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321638452, states[0] = -93.852568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333618535, states[0] = -93.835197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343107072, states[0] = -93.837067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349970818, states[0] = -93.832622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353798128, states[0] = -93.834684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356079070, states[0] = -93.869353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359564170, states[0] = -93.833169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367209714, states[0] = -93.843571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374354406, states[0] = -93.833494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377773517, states[0] = -93.838816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380082757, states[0] = 13.449117, states[40]= 0.001752
Saving checkpoint... 
Iteration: 383620185, states[0] = -93.835140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388635668, states[0] = -93.835090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397955341, states[0] = -93.837753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409765418, states[0] = -93.832827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419997523, states[0] = -93.832518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424461960, states[0] = -93.833263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426213756, states[0] = -93.864340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431131047, states[0] = -93.867324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437813820, states[0] = -93.838508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441357934, states[0] = -93.859629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450280461, states[0] = -93.462879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458729963, states[0] = -93.834756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460284412, states[0] = -93.478655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462558094, states[0] = -93.840230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466640598, states[0] = -93.852373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469762564, states[0] = -93.832771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473231878, states[0] = -93.836396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476240856, states[0] = -93.863355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479741889, states[0] = -93.832790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485401710, states[0] = -93.753972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488360413, states[0] = -93.835885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490961871, states[0] = -93.873590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495050564, states[0] = 25.167821, states[40]= 0.000324
Saving checkpoint... 
Iteration: 499667965, states[0] = -93.832874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504189099, states[0] = -93.833665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507463753, states[0] = -93.840951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510109823, states[0] = 0.800306, states[40]= 0.003776
Saving checkpoint... 
Iteration: 514763455, states[0] = -93.832725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519864777, states[0] = -93.832585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524287171, states[0] = -93.833462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527191583, states[0] = -93.843614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530319696, states[0] = -93.596577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534074440, states[0] = -93.833865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540602202, states[0] = -93.865678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548947728, states[0] = -93.834127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554046026, states[0] = -93.833905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559934038, states[0] = -93.832457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564674727, states[0] = -93.832800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568720337, states[0] = -93.834673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572008144, states[0] = -93.845880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575818910, states[0] = -93.877382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580312071, states[0] = -93.574331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587441882, states[0] = -93.841060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593333939, states[0] = -93.835879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596136623, states[0] = -93.866953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599046174, states[0] = -93.833860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602062687, states[0] = -93.845114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604851283, states[0] = -93.832519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608883292, states[0] = -93.834218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611407796, states[0] = -93.858001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614307724, states[0] = -93.833336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617970407, states[0] = -93.837456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620823492, states[0] = -93.877274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624660457, states[0] = -93.832761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630652687, states[0] = -93.872400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641667335, states[0] = -93.851635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651449046, states[0] = -93.856817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654642652, states[0] = -93.832757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658110717, states[0] = -93.836735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664980291, states[0] = -93.832296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671939565, states[0] = -93.846775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678691908, states[0] = -93.834642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683592522, states[0] = -93.834923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699589046, states[0] = -93.832792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720216478, states[0] = -83.608749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738618617, states[0] = -93.834791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754868033, states[0] = -93.832348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775834573, states[0] = -93.876942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791535074, states[0] = -93.854467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805333389, states[0] = -93.632171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818361938, states[0] = -93.835553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831621770, states[0] = -93.852420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843480156, states[0] = -93.835118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855527327, states[0] = -93.845360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867628209, states[0] = -93.839304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879354907, states[0] = -93.832991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891252851, states[0] = -93.862537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901725050, states[0] = -93.850219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913025539, states[0] = -93.836885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924274075, states[0] = -93.833089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935132335, states[0] = -15.016195, states[40]= 0.001883
Saving checkpoint... 
Iteration: 946281765, states[0] = -93.861522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957202416, states[0] = -93.843066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968883306, states[0] = -93.833861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979467950, states[0] = -93.832703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990287466, states[0] = -93.489952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000916358, states[0] = -93.874624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010918108, states[0] = -93.874558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021980389, states[0] = -93.845827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033335882, states[0] = -93.835435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045746819, states[0] = -93.876903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057000246, states[0] = -93.845510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067753727, states[0] = -93.838255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081333000, states[0] = -93.859757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095602518, states[0] = -93.865185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113431075, states[0] = -93.835016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131626389, states[0] = -93.852022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150094334, states[0] = 8.526056, states[40]= 0.002720
Saving checkpoint... 
Iteration: 1166821812, states[0] = -93.848185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184636904, states[0] = -93.832240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203764970, states[0] = -93.833924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221708303, states[0] = -93.850230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239213428, states[0] = -93.832890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256715987, states[0] = -93.850044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272902405, states[0] = -93.837170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290101088, states[0] = 5.368634, states[40]= 0.003288
Saving checkpoint... 
Iteration: 1308032644, states[0] = -93.836458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327004578, states[0] = -93.845182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345656297, states[0] = -93.872040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363516225, states[0] = -93.834485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381741896, states[0] = -93.849420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399858840, states[0] = -93.831720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415823541, states[0] = -93.876488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433254104, states[0] = -93.835354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453423859, states[0] = -93.834703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476448909, states[0] = -93.856004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493862748, states[0] = -93.833390, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.707431
 - CaMKt in component CaMK (millimolar): 0.001021
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.624149
 - nass in component intracellular_ions (millimolar): 6.624274
 - ki in component intracellular_ions (millimolar): 145.243541
 - kss in component intracellular_ions (millimolar): 145.243532
 - cansr in component intracellular_ions (millimolar): 1.839337
 - cajsr in component intracellular_ions (millimolar): 1.839249
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.004082
 - hf in component INa (dimensionless): 0.857681
 - hs in component INa (dimensionless): 0.857681
 - j in component INa (dimensionless): 0.857681
 - hsp in component INa (dimensionless): 0.685126
 - jp in component INa (dimensionless): 0.857682
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.696539
 - hLp in component INaL (dimensionless): 0.500731
 - a in component Ito (dimensionless): 0.000676
 - iF in component Ito (dimensionless): 0.999839
 - iS in component Ito (dimensionless): 0.999836
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999839
 - iSp in component Ito (dimensionless): 0.999839
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005630
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002180
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997634
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:38:39 (3452): called boinc_finish(0)

</stderr_txt>
]]>


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