𝕏

Task 55678256

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272_0
Workunit 26439970
Created 1 Jul 2024, 16:06:07 UTC
Sent 2 Jul 2024, 11:11:24 UTC
Report deadline 5 Jul 2024, 11:11:24 UTC
Received 4 Jul 2024, 11:08:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222140
Run time 1 hours 11 min 31 sec
CPU time 49 min 27 sec
Validate state Valid
Credit 42.80
Device peak FLOPS 3.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.45 MB
Peak swap size 391.88 GB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272_0_r1015263652_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272_0_r1015263652_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.437609
     * GNaL_b in INaL: 0.005968
     * Gto_b in Ito: 0.086686
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031652
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.167118
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.300723
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037152
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14432535, states[0] = -86.779968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24439100, states[0] = -86.719527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36051308, states[0] = 14.506459, states[40]= 0.004226
Saving checkpoint... 
Iteration: 47450887, states[0] = -86.659431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56575275, states[0] = -86.642592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69609070, states[0] = -86.618525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81580773, states[0] = -86.605850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94429270, states[0] = -86.574601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107203076, states[0] = -86.593754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116532722, states[0] = -86.585561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128117385, states[0] = -13.999912, states[40]= 0.001378
Saving checkpoint... 
Iteration: 138726129, states[0] = -86.589590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150592994, states[0] = -86.582904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161766166, states[0] = -86.572893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175270987, states[0] = -86.577186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185519517, states[0] = -86.573030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195424784, states[0] = -86.573566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206039446, states[0] = 18.797445, states[40]= 0.004336
Saving checkpoint... 
Iteration: 216634630, states[0] = -86.579977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229660055, states[0] = -86.569666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240193402, states[0] = -84.669401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253587359, states[0] = -86.569937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264491468, states[0] = -86.564756, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272_0_r1015263652_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_272_0_r1015263652_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.437609
     * GNaL_b in INaL: 0.005968
     * Gto_b in Ito: 0.086686
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031652
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.167118
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.300723
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037152
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 264491468
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.564756 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 276375086, states[0] = -86.526676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288648963, states[0] = -86.579415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301042107, states[0] = -86.577567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314333212, states[0] = -86.499398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327668244, states[0] = -86.568652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337571925, states[0] = -86.569586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349658444, states[0] = -86.568699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360388518, states[0] = -86.533070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369111855, states[0] = -86.576155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381648550, states[0] = -86.568756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392253182, states[0] = -86.408591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403464764, states[0] = -86.570740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415652508, states[0] = -86.568697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430223900, states[0] = -86.363871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442524917, states[0] = -86.569584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454753110, states[0] = -86.580903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467255663, states[0] = -86.573665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479857404, states[0] = -86.566987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489813521, states[0] = -86.567306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502611344, states[0] = -86.577423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513806659, states[0] = -86.567353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525941610, states[0] = -86.566412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535096359, states[0] = -86.576365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544939787, states[0] = -86.579120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555569352, states[0] = -86.569496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567361962, states[0] = -86.572049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579628494, states[0] = -86.568886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589587096, states[0] = -86.569303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608086422, states[0] = 4.731733, states[40]= 0.003997
Saving checkpoint... 
Iteration: 625758188, states[0] = -86.567714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638211791, states[0] = -86.336705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650761611, states[0] = -86.580877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663274196, states[0] = -86.573334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676106106, states[0] = -5.170248, states[40]= 0.002864
Saving checkpoint... 
Iteration: 686974438, states[0] = -86.578511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700776767, states[0] = -86.580860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711706273, states[0] = -86.568139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723338722, states[0] = -86.572352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734394999, states[0] = -86.535902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745970989, states[0] = -86.566188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754811830, states[0] = -86.580691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768039258, states[0] = 18.857327, states[40]= 0.004342
Saving checkpoint... 
Iteration: 779395751, states[0] = -86.571545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790157425, states[0] = -47.289912, states[40]= 0.000041
Saving checkpoint... 
Iteration: 800851532, states[0] = -86.580318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810597105, states[0] = -86.576499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819130902, states[0] = -86.575698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830415158, states[0] = -86.544005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842016463, states[0] = 21.790532, states[40]= 0.012229
Saving checkpoint... 
Iteration: 852503535, states[0] = -86.566315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864875990, states[0] = -86.580009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876698277, states[0] = -86.580324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886410419, states[0] = -86.542218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897865087, states[0] = -86.566853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910425557, states[0] = -86.547632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921511251, states[0] = -86.570074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932985338, states[0] = -86.578277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943963574, states[0] = -86.566197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952454961, states[0] = -86.556246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964023976, states[0] = 21.419877, states[40]= 0.006125
Saving checkpoint... 
Iteration: 974554910, states[0] = -86.572994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983921326, states[0] = -86.566457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997430429, states[0] = -86.571047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009303077, states[0] = -86.572827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019843294, states[0] = -86.566987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030690517, states[0] = -86.580157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041108956, states[0] = -86.576047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052071442, states[0] = 10.182466, states[40]= 0.004182
Saving checkpoint... 
Iteration: 1064982043, states[0] = -86.578310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075966947, states[0] = -86.566152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087288505, states[0] = -86.573035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099374285, states[0] = -86.571779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112034366, states[0] = 19.866232, states[40]= 0.004589
Saving checkpoint... 
Iteration: 1122827109, states[0] = -86.580503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133181134, states[0] = -86.574769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144077995, states[0] = 7.943936, states[40]= 0.004129
Saving checkpoint... 
Iteration: 1156223060, states[0] = -86.362449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167110691, states[0] = -86.575993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176700462, states[0] = -86.580305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188361062, states[0] = -86.518258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201078531, states[0] = -86.576562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212459621, states[0] = -86.557366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226408847, states[0] = -86.541549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236543850, states[0] = -86.571767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246404209, states[0] = -86.539704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256811653, states[0] = -86.580600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270173975, states[0] = -63.562811, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1282360189, states[0] = -86.517713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294178026, states[0] = -68.345983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306261752, states[0] = -86.420998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316844525, states[0] = -86.580299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327101831, states[0] = -86.576121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337280515, states[0] = -86.573112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348268941, states[0] = -86.431069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359249858, states[0] = -86.573591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370746068, states[0] = -86.580708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385665126, states[0] = -86.568388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395979499, states[0] = -86.566018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408118435, states[0] = -14.325658, states[40]= 0.001334
Saving checkpoint... 
Iteration: 1418316476, states[0] = -86.484929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430139992, states[0] = -32.181731, states[40]= 0.000388
Saving checkpoint... 
Iteration: 1439853534, states[0] = -86.566836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451818071, states[0] = -86.567094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465882476, states[0] = -86.566628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477314454, states[0] = -86.572571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489154709, states[0] = -86.575158, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.441846
 - CaMKt in component CaMK (millimolar): 0.000883
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.005043
 - nass in component intracellular_ions (millimolar): 6.005088
 - ki in component intracellular_ions (millimolar): 145.992075
 - kss in component intracellular_ions (millimolar): 145.992064
 - cansr in component intracellular_ions (millimolar): 1.244497
 - cajsr in component intracellular_ions (millimolar): 1.244644
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008484
 - hf in component INa (dimensionless): 0.646193
 - hs in component INa (dimensionless): 0.646193
 - j in component INa (dimensionless): 0.646196
 - hsp in component INa (dimensionless): 0.397384
 - jp in component INa (dimensionless): 0.646198
 - mL in component INaL (dimensionless): 0.000247
 - hL in component INaL (dimensionless): 0.465219
 - hLp in component INaL (dimensionless): 0.275150
 - a in component Ito (dimensionless): 0.001103
 - iF in component Ito (dimensionless): 0.999427
 - iS in component Ito (dimensionless): 0.985524
 - ap in component Ito (dimensionless): 0.000562
 - iFp in component Ito (dimensionless): 0.999427
 - iSp in component Ito (dimensionless): 0.991644
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997449
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001244
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020428
 - xs1 in component IKs (dimensionless): 0.037788
 - xs2 in component IKs (dimensionless): 0.000226
 - xk1 in component IK1 (dimensionless): 0.997116
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:38:40 (77637): called boinc_finish(0)

</stderr_txt>
]]>


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