𝕏

Task 55670428

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_565_1
Workunit 26436063
Created 1 Jul 2024, 16:02:40 UTC
Sent 2 Jul 2024, 9:58:58 UTC
Report deadline 5 Jul 2024, 9:58:58 UTC
Received 3 Jul 2024, 5:56:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233458
Run time 1 hours 53 min 44 sec
CPU time 1 hours 53 min 28 sec
Validate state Valid
Credit 43.62
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_565.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_565_1_r1086071327_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_565_1_r1086071327_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.857549
     * GNaL_b in INaL: 0.005488
     * Gto_b in Ito: 0.086011
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031882
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.159993
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.691175
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032090
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8646595, states[0] = -94.093003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17047041, states[0] = -94.013386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25701501, states[0] = -82.536262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34254791, states[0] = -93.965572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39479529, states[0] = -93.933211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48018005, states[0] = 31.478662, states[40]= 0.003707
Saving checkpoint... 
Iteration: 56474667, states[0] = -93.966910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65195300, states[0] = -93.972143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73837844, states[0] = -93.764823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82450112, states[0] = -93.946943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91016586, states[0] = -93.964481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99643671, states[0] = -93.969238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108350712, states[0] = -93.790700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117009034, states[0] = 30.189968, states[40]= 0.083618
Saving checkpoint... 
Iteration: 125739553, states[0] = -93.955035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134670594, states[0] = -93.957948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143455570, states[0] = -93.967558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152279957, states[0] = -93.973278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161050387, states[0] = -93.954333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169606073, states[0] = -0.086943, states[40]= 0.003357
Saving checkpoint... 
Iteration: 178296472, states[0] = -93.952840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186921561, states[0] = -93.968983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195504673, states[0] = -93.939042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204013021, states[0] = 31.098242, states[40]= 0.020900
Saving checkpoint... 
Iteration: 212669522, states[0] = -93.957938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221227202, states[0] = -93.973198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229712430, states[0] = -91.177220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238416123, states[0] = -93.948372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243727460, states[0] = -93.973136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252364635, states[0] = -93.814939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260954377, states[0] = -93.947033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269292704, states[0] = -93.972837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277161805, states[0] = -93.958077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285550874, states[0] = -93.954151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294157830, states[0] = -40.346443, states[40]= 0.000774
Saving checkpoint... 
Iteration: 302873278, states[0] = -93.949654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311569531, states[0] = -93.962056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320241637, states[0] = -93.973016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328977502, states[0] = -93.925698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337764389, states[0] = -93.533847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346375217, states[0] = -93.949441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355068027, states[0] = -93.961980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363876074, states[0] = -93.970213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372504825, states[0] = -93.938555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381302638, states[0] = -93.674712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390110957, states[0] = -3.243085, states[40]= 0.003298
Saving checkpoint... 
Iteration: 398701874, states[0] = -93.955970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407197782, states[0] = -93.971928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415835477, states[0] = -93.759413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424470536, states[0] = -93.945972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433065919, states[0] = -93.961815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441575442, states[0] = -93.959266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450119986, states[0] = -10.145891, states[40]= 0.002345
Saving checkpoint... 
Iteration: 458761452, states[0] = -93.953339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467544304, states[0] = -93.962680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476174629, states[0] = -93.970704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484891459, states[0] = -93.852433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493758581, states[0] = -93.507279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502516292, states[0] = 31.447512, states[40]= 0.006724
Saving checkpoint... 
Iteration: 508432978, states[0] = -93.946916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517193434, states[0] = -93.955929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525554845, states[0] = -93.954366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534131938, states[0] = -20.164902, states[40]= 0.001641
Saving checkpoint... 
Iteration: 542759694, states[0] = -93.953128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551369958, states[0] = -93.969805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560022722, states[0] = -93.944734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568618769, states[0] = -9.144361, states[40]= 0.002512
Saving checkpoint... 
Iteration: 577208528, states[0] = -93.955096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585769363, states[0] = -93.972080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594354509, states[0] = -93.796492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602949343, states[0] = -93.946060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611503873, states[0] = -93.964030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620077824, states[0] = -93.959141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626286771, states[0] = -93.971744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634862309, states[0] = -93.809838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643468203, states[0] = -93.945314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652151641, states[0] = -93.957268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660818016, states[0] = -93.971010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669684589, states[0] = -93.970542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678397184, states[0] = -93.858724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687101656, states[0] = 2.466103, states[40]= 0.003182
Saving checkpoint... 
Iteration: 695882517, states[0] = -93.948015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704356625, states[0] = -93.969748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712951505, states[0] = -93.908391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721431716, states[0] = -93.946245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729921047, states[0] = -93.967245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738492943, states[0] = -93.932101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743680870, states[0] = -93.955704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752195257, states[0] = -93.970690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760716948, states[0] = -92.606553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769286718, states[0] = -93.951309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777888012, states[0] = -93.968391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786430290, states[0] = -93.891738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795220366, states[0] = -93.030198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803904940, states[0] = -93.946875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812617900, states[0] = -93.958214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821311415, states[0] = -93.970629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830094918, states[0] = -93.961474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838749211, states[0] = -93.461609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847449163, states[0] = -93.945247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856125244, states[0] = -93.957743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864952415, states[0] = -93.965466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873658221, states[0] = -93.968372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882557575, states[0] = -93.953846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891103520, states[0] = 1.418444, states[40]= 0.003275
Saving checkpoint... 
Iteration: 899594413, states[0] = -93.958971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908320685, states[0] = -93.970117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917056254, states[0] = -93.953408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925680719, states[0] = -58.846000, states[40]= 0.000054
Saving checkpoint... 
Iteration: 934244050, states[0] = -93.952445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942729975, states[0] = -93.970845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951165463, states[0] = -46.459892, states[40]= 0.000353
Saving checkpoint... 
Iteration: 959761537, states[0] = -93.951660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968379241, states[0] = -93.968080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976296505, states[0] = -93.950239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984821886, states[0] = -93.969832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993326936, states[0] = -93.738045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001941311, states[0] = -93.944988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010530885, states[0] = -93.961474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019005667, states[0] = -93.936743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027484433, states[0] = -93.943513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036128440, states[0] = -93.957001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044936782, states[0] = -93.965535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053809458, states[0] = -93.969897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062551440, states[0] = -93.951706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071311307, states[0] = -93.697580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080176456, states[0] = -55.363770, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1088963951, states[0] = -93.943959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097461773, states[0] = -93.964282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105972996, states[0] = -93.920603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114554721, states[0] = 22.530772, states[40]= 0.000394
Saving checkpoint... 
Iteration: 1123206667, states[0] = -93.953348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131991963, states[0] = -93.962827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137601843, states[0] = -93.961518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146167464, states[0] = -48.078386, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1154697971, states[0] = -93.953607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163384462, states[0] = -93.967237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172032892, states[0] = -93.946046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180542700, states[0] = 26.560709, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1189120954, states[0] = -93.956820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197713464, states[0] = -93.969720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206327285, states[0] = -93.738151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211421474, states[0] = -93.965619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219979837, states[0] = -93.923971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228572073, states[0] = 15.976302, states[40]= 0.001033
Saving checkpoint... 
Iteration: 1237381804, states[0] = -93.946228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246209485, states[0] = -93.952819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254641541, states[0] = -93.965778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263484689, states[0] = -93.926337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272078866, states[0] = 13.202227, states[40]= 0.001441
Saving checkpoint... 
Iteration: 1280723916, states[0] = -93.952107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288234339, states[0] = -93.951655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296674653, states[0] = -93.967967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305209272, states[0] = -89.054909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313794440, states[0] = -93.949189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322580927, states[0] = -93.958164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331343310, states[0] = -93.968076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340030235, states[0] = -93.944641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348446041, states[0] = -93.943673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357225474, states[0] = -93.951787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365831249, states[0] = -93.968311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374644275, states[0] = -93.965617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383319957, states[0] = -93.719560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392061068, states[0] = 20.219248, states[40]= 0.000569
Saving checkpoint... 
Iteration: 1401037647, states[0] = 28.056483, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1409724649, states[0] = -93.951645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418418195, states[0] = -93.965063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427273541, states[0] = -93.969234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436083276, states[0] = -93.957448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442558803, states[0] = -93.958764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451031287, states[0] = -93.944607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459566761, states[0] = 18.061035, states[40]= 0.000780
Saving checkpoint... 
Iteration: 1468221362, states[0] = -93.951585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476923744, states[0] = -93.964639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485536082, states[0] = -93.945983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494141115, states[0] = -27.351588, states[40]= 0.002129
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.817405
 - CaMKt in component CaMK (millimolar): 0.003142
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.794574
 - nass in component intracellular_ions (millimolar): 6.794696
 - ki in component intracellular_ions (millimolar): 145.055143
 - kss in component intracellular_ions (millimolar): 145.055131
 - cansr in component intracellular_ions (millimolar): 1.842311
 - cajsr in component intracellular_ions (millimolar): 1.842136
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004037
 - hf in component INa (dimensionless): 0.859873
 - hs in component INa (dimensionless): 0.859875
 - j in component INa (dimensionless): 0.859882
 - hsp in component INa (dimensionless): 0.689020
 - jp in component INa (dimensionless): 0.859887
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699727
 - hLp in component INaL (dimensionless): 0.501208
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999842
 - iS in component Ito (dimensionless): 0.968731
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999842
 - iSp in component Ito (dimensionless): 0.984122
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990252
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005091
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030220
 - xs1 in component IKs (dimensionless): 0.072218
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997608
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:55:02 (1596): called boinc_finish(0)

</stderr_txt>
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