𝕏

Task 55650568

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_446_1
Workunit 26426152
Created 1 Jul 2024, 15:53:56 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 3 Jul 2024, 10:23:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 50 min 45 sec
CPU time 1 hours 41 min 56 sec
Validate state Valid
Credit 43.77
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.00 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_446.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_446_1_r1775569920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_446_1_r1775569920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.409233
     * GNaL_b in INaL: 0.005670
     * Gto_b in Ito: 0.085786
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.168166
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.222490
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030538
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11355896, states[0] = -94.249160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22415669, states[0] = -94.215038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 30604486, states[0] = -94.219747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40476463, states[0] = -94.149476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51465977, states[0] = -94.245417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62075104, states[0] = -94.241591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72356417, states[0] = -94.244587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79422581, states[0] = -94.252018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89781555, states[0] = -94.252162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100055910, states[0] = 30.911505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107413146, states[0] = -94.256037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117330925, states[0] = -94.258474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127462423, states[0] = -94.259170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137709982, states[0] = -28.752998, states[40]= 0.005696
Saving checkpoint... 
Iteration: 148691150, states[0] = -94.281854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158980115, states[0] = -94.274576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169291567, states[0] = -94.269018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179757637, states[0] = -94.264081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190368710, states[0] = -94.024898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200908000, states[0] = -94.291546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211916773, states[0] = -94.268084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222473840, states[0] = -94.263261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233088813, states[0] = -94.265512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243449276, states[0] = -94.290899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253500500, states[0] = -94.289584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263461589, states[0] = -94.290542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273480368, states[0] = -94.290022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283942099, states[0] = -94.276667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294654274, states[0] = -94.265269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305172857, states[0] = -15.562720, states[40]= 0.000911
Saving checkpoint... 
Iteration: 316175238, states[0] = -94.283897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326064297, states[0] = -94.287248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336402961, states[0] = -94.277240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346542775, states[0] = -94.273856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357193601, states[0] = -94.264411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367643282, states[0] = -0.366607, states[40]= 0.000312
Saving checkpoint... 
Iteration: 378005415, states[0] = -94.224487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388354037, states[0] = -94.291184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398986378, states[0] = -94.274659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409276173, states[0] = -94.268942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419504565, states[0] = -94.265742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430209504, states[0] = -29.166553, states[40]= 0.005466
Saving checkpoint... 
Iteration: 440883197, states[0] = -94.290513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451933639, states[0] = -94.266307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462824719, states[0] = -93.873947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473055414, states[0] = -94.251327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482812789, states[0] = -93.820285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492656338, states[0] = -6.412307, states[40]= 0.000540
Saving checkpoint... 
Iteration: 503135466, states[0] = -94.275210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513824147, states[0] = -94.277756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524275857, states[0] = -94.267906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534514348, states[0] = -94.264588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545130861, states[0] = 4.507760, states[40]= 0.000138
Saving checkpoint... 
Iteration: 555734938, states[0] = -94.286757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566673757, states[0] = -94.269265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577170675, states[0] = -94.262627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587570842, states[0] = 26.297801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598375505, states[0] = -94.289161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608630148, states[0] = -94.282685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619432122, states[0] = -94.264808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629561347, states[0] = -94.263212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640479738, states[0] = -94.201867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651610220, states[0] = -94.269705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662570484, states[0] = 26.414994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672118223, states[0] = -94.262250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683122520, states[0] = -94.270834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693600830, states[0] = -94.282824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704387905, states[0] = -94.264617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714261580, states[0] = -94.266410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725428454, states[0] = -94.142042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735889011, states[0] = -94.287775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745346161, states[0] = -93.953036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755747885, states[0] = -94.285684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766646255, states[0] = -94.267963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777083315, states[0] = -94.261645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787219207, states[0] = -94.260305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797540050, states[0] = 33.617038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808432228, states[0] = -94.286411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815651431, states[0] = -94.275292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826660824, states[0] = -94.267145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837809280, states[0] = -93.800066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848310844, states[0] = -94.286805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 859153572, states[0] = -94.266985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869660959, states[0] = -94.260058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 877794489, states[0] = -93.714185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888107153, states[0] = -94.265225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898327911, states[0] = -94.286522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909168078, states[0] = -94.266261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920448228, states[0] = -94.166579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931336655, states[0] = -94.273623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941645632, states[0] = -94.266386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 952276434, states[0] = -94.258357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962246491, states[0] = -94.258497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972345041, states[0] = -94.257691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982984571, states[0] = -94.202942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993308011, states[0] = -94.285448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003699831, states[0] = -94.276948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1014127481, states[0] = -94.266076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024910421, states[0] = -94.256802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033766696, states[0] = -94.274675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044225089, states[0] = -94.264023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054506894, states[0] = -94.259951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064992230, states[0] = -94.255990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072263710, states[0] = -94.257363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082744696, states[0] = -51.404610, states[40]= 0.000453
Saving checkpoint... 
Iteration: 1092745951, states[0] = -52.379697, states[40]= 0.000392
Saving checkpoint... 
Iteration: 1103651354, states[0] = -94.277536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114103526, states[0] = -94.265642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124004858, states[0] = -94.267659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134424073, states[0] = -94.260233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145157204, states[0] = -6.856641, states[40]= 0.000552
Saving checkpoint... 
Iteration: 1154849754, states[0] = -94.256000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165040121, states[0] = 33.610846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175176883, states[0] = -17.564703, states[40]= 0.001336
Saving checkpoint... 
Iteration: 1185579051, states[0] = -94.254018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196651052, states[0] = -94.263969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207136950, states[0] = -94.257213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214267277, states[0] = -94.261778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224725176, states[0] = -94.256281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1235618941, states[0] = -94.264997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245764171, states[0] = -94.281985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256757242, states[0] = -94.261555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1267776839, states[0] = -88.806506, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1278601987, states[0] = -94.277484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289445135, states[0] = -94.258557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299237760, states[0] = -94.261493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306771367, states[0] = -94.260873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316169740, states[0] = -94.275039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326788722, states[0] = -94.260416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337808505, states[0] = -93.791540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348043313, states[0] = -94.237815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358821446, states[0] = -94.270163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368908369, states[0] = -94.267756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1379208069, states[0] = -94.261274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390224494, states[0] = -37.030067, states[40]= 0.002868
Saving checkpoint... 
Iteration: 1400578681, states[0] = -94.251935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407882851, states[0] = -94.050895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415717645, states[0] = -94.277742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1426428612, states[0] = -94.266727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436552926, states[0] = -94.263763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445994928, states[0] = -94.279132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456451857, states[0] = -94.265885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466823044, states[0] = -94.258620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477534947, states[0] = 33.981063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488306962, states[0] = -94.280946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498914757, states[0] = -94.266416, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.127974
 - CaMKt in component CaMK (millimolar): 0.001800
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.758441
 - nass in component intracellular_ions (millimolar): 7.758594
 - ki in component intracellular_ions (millimolar): 144.053340
 - kss in component intracellular_ions (millimolar): 144.053325
 - cansr in component intracellular_ions (millimolar): 1.805088
 - cajsr in component intracellular_ions (millimolar): 1.806577
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003912
 - hf in component INa (dimensionless): 0.865909
 - hs in component INa (dimensionless): 0.865910
 - j in component INa (dimensionless): 0.865911
 - hsp in component INa (dimensionless): 0.699841
 - jp in component INa (dimensionless): 0.865911
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708291
 - hLp in component INaL (dimensionless): 0.514651
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.997227
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999045
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998053
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004463
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002401
 - xs1 in component IKs (dimensionless): 0.032403
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997533
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
05:31:41 (24778): called boinc_finish(0)

</stderr_txt>
]]>


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