𝕏

Task 55650503

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246_0
Workunit 26426120
Created 1 Jul 2024, 15:53:56 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 6:37:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 52 min 46 sec
CPU time 1 hours 42 min 35 sec
Validate state Valid
Credit 45.42
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246_0_r625889662_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246_0_r625889662_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.647188
     * GNaL_b in INaL: 0.005440
     * Gto_b in Ito: 0.083347
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032348
     * GKs_b in IKs: 0.001964
     * GK1_b in IK1: 0.166929
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.179719
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031272
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7185365, states[0] = -16.130717, states[40]= 0.000788
Saving checkpoint... 
Iteration: 13887887, states[0] = -94.297762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23903132, states[0] = -94.294998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34854858, states[0] = -94.308948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44554906, states[0] = -94.297677, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246_0_r625889662_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_2000-conf_246_0_r625889662_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.647188
     * GNaL_b in INaL: 0.005440
     * Gto_b in Ito: 0.083347
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032348
     * GKs_b in IKs: 0.001964
     * GK1_b in IK1: 0.166929
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.179719
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031272
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 44554906
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.297677 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 54668196, states[0] = -94.331764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64706956, states[0] = -94.343592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74303974, states[0] = -93.898654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83960145, states[0] = -94.349630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93589818, states[0] = -94.348329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103641492, states[0] = -94.360460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114508364, states[0] = -94.325524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121588504, states[0] = -94.356127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131756302, states[0] = -94.371248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141752810, states[0] = -94.372306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151989685, states[0] = -94.363284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162703310, states[0] = -94.372834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172118981, states[0] = 4.543343, states[40]= 0.000339
Saving checkpoint... 
Iteration: 181423470, states[0] = -94.257860, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190972120, states[0] = -94.365042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198662225, states[0] = -94.370851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208153819, states[0] = -15.225743, states[40]= 0.001417
Saving checkpoint... 
Iteration: 214878866, states[0] = -94.369667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224696985, states[0] = -94.372412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234349163, states[0] = -94.108551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243654347, states[0] = -94.369227, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253668168, states[0] = -94.370057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263923406, states[0] = -94.366099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274286945, states[0] = -93.844153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284428507, states[0] = -94.262151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294243860, states[0] = -84.209522, states[40]= 0.000007
Saving checkpoint... 
Iteration: 301111775, states[0] = 7.649571, states[40]= 0.000192
Saving checkpoint... 
Iteration: 311852332, states[0] = -94.367962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322698398, states[0] = -94.369412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332480077, states[0] = -94.309940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341914442, states[0] = -94.363946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352073200, states[0] = 23.326462, states[40]= 0.000003
Saving checkpoint... 
Iteration: 361636566, states[0] = -94.363464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371696797, states[0] = -94.367648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381886189, states[0] = -94.363984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392084512, states[0] = 18.983492, states[40]= 0.000013
Saving checkpoint... 
Iteration: 402065020, states[0] = 26.247424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413257093, states[0] = -93.491225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419748423, states[0] = -94.366858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430476297, states[0] = -94.303716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440313893, states[0] = -93.975032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450151363, states[0] = -13.691823, states[40]= 0.001274
Saving checkpoint... 
Iteration: 460681589, states[0] = -94.363824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470712184, states[0] = -94.364693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480870360, states[0] = -94.361292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491082970, states[0] = 19.593336, states[40]= 0.000011
Saving checkpoint... 
Iteration: 500953958, states[0] = -94.356257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510811457, states[0] = -94.362559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521349173, states[0] = -94.098817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531795884, states[0] = -94.362261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542487736, states[0] = -94.307919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552527248, states[0] = -94.329169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563732458, states[0] = -94.361766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573857781, states[0] = -94.358587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583307153, states[0] = -93.939477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593733247, states[0] = -94.360717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603841765, states[0] = -94.358203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 613783737, states[0] = -94.359659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 624418989, states[0] = -94.237817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631460447, states[0] = -94.283675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641226627, states[0] = -61.029385, states[40]= 0.000201
Saving checkpoint... 
Iteration: 651722222, states[0] = -94.358544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661796067, states[0] = -94.357691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672577253, states[0] = -94.341911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683131514, states[0] = -1.545837, states[40]= 0.000787
Saving checkpoint... 
Iteration: 693408435, states[0] = -94.220057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703695363, states[0] = -94.355963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713221211, states[0] = -56.317709, states[40]= 0.000400
Saving checkpoint... 
Iteration: 723706050, states[0] = -94.355641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733780434, states[0] = -94.355512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743916715, states[0] = -94.349750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753538948, states[0] = -94.326941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763769051, states[0] = -94.354644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775382628, states[0] = -94.171543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785419462, states[0] = -94.232770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795588133, states[0] = -94.340180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805195605, states[0] = -37.232089, states[40]= 0.004167
Saving checkpoint... 
Iteration: 815211247, states[0] = -48.356278, states[40]= 0.001184
Saving checkpoint... 
Iteration: 825772693, states[0] = -94.352438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835970783, states[0] = -94.343570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846856202, states[0] = -94.349100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857176000, states[0] = -26.605111, states[40]= 0.007131
Saving checkpoint... 
Iteration: 867384952, states[0] = -94.172958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878012514, states[0] = 31.183234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888489203, states[0] = -94.296716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898638205, states[0] = -94.344847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908844492, states[0] = -94.347410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919287278, states[0] = -93.822942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929732335, states[0] = -94.348935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940676592, states[0] = -94.346713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950529439, states[0] = -94.316139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960524182, states[0] = -94.313460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970941055, states[0] = -94.340486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980490971, states[0] = -94.294625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987561249, states[0] = -94.326418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997996462, states[0] = -94.336408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008443857, states[0] = -94.254295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018955285, states[0] = -94.338011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1029778631, states[0] = -94.345178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1040329946, states[0] = -94.017472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051157626, states[0] = -17.586331, states[40]= 0.001909
Saving checkpoint... 
Iteration: 1061388429, states[0] = -94.172801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072212034, states[0] = -48.945285, states[40]= 0.001097
Saving checkpoint... 
Iteration: 1082531636, states[0] = -94.312432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092961690, states[0] = -94.335056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102895238, states[0] = -94.338277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113332460, states[0] = -94.023859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123658840, states[0] = -94.339004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1130862626, states[0] = -94.338847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141131662, states[0] = -1.607338, states[40]= 0.000790
Saving checkpoint... 
Iteration: 1151518660, states[0] = -94.304152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158357488, states[0] = -94.099334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169159620, states[0] = -18.727539, states[40]= 0.002343
Saving checkpoint... 
Iteration: 1179771001, states[0] = -94.340059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190377802, states[0] = -94.146833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201306041, states[0] = -93.912027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211768959, states[0] = -94.338967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221867056, states[0] = -94.335472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232781166, states[0] = -94.338029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243421089, states[0] = -94.218824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254577687, states[0] = -94.321612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265560440, states[0] = -94.316417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1276580201, states[0] = -94.321462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287249042, states[0] = -90.996926, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1297497132, states[0] = -94.287345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1308158691, states[0] = -18.194053, states[40]= 0.002120
Saving checkpoint... 
Iteration: 1319227794, states[0] = -62.045623, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1329455406, states[0] = -94.254487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339976281, states[0] = -94.325581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350097478, states[0] = 13.728917, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1359704235, states[0] = -94.333298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369585147, states[0] = -94.319368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380154420, states[0] = -15.610504, states[40]= 0.001464
Saving checkpoint... 
Iteration: 1390288275, states[0] = -93.811679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400923192, states[0] = -94.326381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411718590, states[0] = -94.331844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418823169, states[0] = -94.330340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429161182, states[0] = -19.571213, states[40]= 0.002768
Saving checkpoint... 
Iteration: 1440577959, states[0] = -94.315143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1451502874, states[0] = -94.285307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462310241, states[0] = -93.922118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473482008, states[0] = -94.271203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484480338, states[0] = -94.269617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494213370, states[0] = -49.953037, states[40]= 0.000960
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.194549
 - CaMKt in component CaMK (millimolar): 0.009676
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 8.180164
 - nass in component intracellular_ions (millimolar): 8.180341
 - ki in component intracellular_ions (millimolar): 143.365972
 - kss in component intracellular_ions (millimolar): 143.365948
 - cansr in component intracellular_ions (millimolar): 2.118899
 - cajsr in component intracellular_ions (millimolar): 2.121446
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003886
 - hf in component INa (dimensionless): 0.867175
 - hs in component INa (dimensionless): 0.867178
 - j in component INa (dimensionless): 0.867191
 - hsp in component INa (dimensionless): 0.702147
 - jp in component INa (dimensionless): 0.867198
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709866
 - hLp in component INaL (dimensionless): 0.492264
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.872373
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.914407
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.960137
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005363
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.123681
 - xs1 in component IKs (dimensionless): 0.167123
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997517
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:30:11 (41434): called boinc_finish(0)

</stderr_txt>
]]>


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