𝕏

Task 55650432

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546_1
Workunit 26426084
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 6:37:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 54 min 10 sec
CPU time 1 hours 44 min 40 sec
Validate state Valid
Credit 44.84
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.00 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546_1_r1175106943_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546_1_r1175106943_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.250746
     * GNaL_b in INaL: 0.005513
     * Gto_b in Ito: 0.087665
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031324
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.160114
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.218276
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031709
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11128612, states[0] = -94.311325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19987933, states[0] = -94.236895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30427502, states[0] = -94.187696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40743892, states[0] = -94.225038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50967400, states[0] = -94.212419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61037222, states[0] = -94.209525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71897536, states[0] = -94.188486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82626718, states[0] = -16.249296, states[40]= 0.000303
Saving checkpoint... 
Iteration: 93047905, states[0] = -94.220692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103127742, states[0] = -94.230024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109354149, states[0] = -94.196986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116578840, states[0] = -94.203334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127269337, states[0] = -94.193849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137798681, states[0] = -93.988139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148008085, states[0] = -94.219251, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546_1_r1175106943_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_546_1_r1175106943_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.250746
     * GNaL_b in INaL: 0.005513
     * Gto_b in Ito: 0.087665
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031324
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.160114
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.218276
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031709
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 148008085
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.219251 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 157624800, states[0] = -15.100824, states[40]= 0.000303
Saving checkpoint... 
Iteration: 167390566, states[0] = -94.195086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177275944, states[0] = -94.196428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187607878, states[0] = -0.114479, states[40]= 0.000211
Saving checkpoint... 
Iteration: 197224498, states[0] = -94.197237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207407073, states[0] = -94.195512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217007687, states[0] = -94.199953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224015767, states[0] = -94.209041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233317685, states[0] = -94.234061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243336094, states[0] = -94.233293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253994168, states[0] = -94.209448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263647206, states[0] = -94.220153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273273604, states[0] = -94.235380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283111512, states[0] = -94.235106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292770311, states[0] = -93.890869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301770160, states[0] = -94.203192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311854398, states[0] = -94.201654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318526629, states[0] = -94.224515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328658017, states[0] = -94.219184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338602495, states[0] = -94.221221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347173261, states[0] = -94.196944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357031871, states[0] = -94.198594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366763900, states[0] = -94.202684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376732195, states[0] = -94.203172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386439072, states[0] = -94.209681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396372682, states[0] = -94.211431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403412181, states[0] = -94.228645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413596943, states[0] = -94.220701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423891251, states[0] = -94.210624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433830565, states[0] = -94.212309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443161247, states[0] = -94.235264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452993671, states[0] = -94.214482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462864346, states[0] = -94.121975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472815334, states[0] = -94.032299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482786911, states[0] = -93.950956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493041121, states[0] = -94.225367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502885987, states[0] = -94.147645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513949832, states[0] = -94.208117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520299979, states[0] = -93.991365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530290865, states[0] = -93.963496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540475516, states[0] = -94.207271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551302273, states[0] = -94.212005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561078725, states[0] = -94.219950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570620736, states[0] = -94.232778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581303925, states[0] = -94.211653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590993614, states[0] = -94.223213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600963093, states[0] = -94.224438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610521738, states[0] = -94.220364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620767012, states[0] = -94.232186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631129313, states[0] = -94.217256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640886067, states[0] = -94.227403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650240038, states[0] = -93.737580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660456007, states[0] = -94.197609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669937426, states[0] = -94.191098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679498913, states[0] = -94.195809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689908067, states[0] = -94.191150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699583795, states[0] = -94.194483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709104970, states[0] = -94.202422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719108937, states[0] = -94.202235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726137058, states[0] = -94.216002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736270397, states[0] = -94.211174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746748555, states[0] = -94.199151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757372171, states[0] = -94.190792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767129547, states[0] = -94.193241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777587446, states[0] = 11.709837, states[40]= 0.000027
Saving checkpoint... 
Iteration: 788106788, states[0] = -94.229820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798330190, states[0] = -94.228151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807705057, states[0] = -93.483449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817889180, states[0] = -94.147809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828205422, states[0] = -94.231433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838475401, states[0] = -94.221519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847903697, states[0] = -94.161249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857245555, states[0] = -94.191034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867498559, states[0] = -94.188607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877203181, states[0] = -94.191292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887280131, states[0] = -94.190376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897307552, states[0] = -94.190001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907780679, states[0] = -93.924788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917382230, states[0] = -94.189093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927310837, states[0] = -94.189665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936805398, states[0] = -94.196224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946814128, states[0] = -94.195972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957454879, states[0] = -94.188057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967666891, states[0] = -61.355860, states[40]= 0.000026
Saving checkpoint... 
Iteration: 977543345, states[0] = 26.011864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987762625, states[0] = -93.850646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998082467, states[0] = -94.225785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008318333, states[0] = -94.226510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018936645, states[0] = -94.203394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028776172, states[0] = -94.208047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038667156, states[0] = -94.211735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049041773, states[0] = -94.200445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059006478, states[0] = -94.201197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068723571, states[0] = -94.209415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075568675, states[0] = -94.223529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085235177, states[0] = -93.703972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095571735, states[0] = -94.223685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105943912, states[0] = -94.220213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116650179, states[0] = -94.197366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126576101, states[0] = -94.198874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137137742, states[0] = -94.189427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146220593, states[0] = -94.208744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156375819, states[0] = -94.203713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167116360, states[0] = -94.189383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177259221, states[0] = -94.187675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187092534, states[0] = -94.189476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197561858, states[0] = 22.134957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207978587, states[0] = -94.201748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215005271, states[0] = 14.927475, states[40]= 0.582433
Saving checkpoint... 
Iteration: 1225436162, states[0] = -94.181172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235628297, states[0] = -94.226455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242840956, states[0] = -94.077636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253609792, states[0] = -94.211767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264224079, states[0] = -94.194413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274817371, states[0] = -94.186109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285411482, states[0] = -94.163348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296483323, states[0] = -94.199393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306852407, states[0] = -94.191715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317578715, states[0] = 15.799563, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1328060859, states[0] = -94.220018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338756221, states[0] = -94.205597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349463192, states[0] = -94.189581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359070219, states[0] = -94.196673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369667468, states[0] = -94.186742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380880064, states[0] = -94.220243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391447340, states[0] = -94.199374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401922483, states[0] = -94.189658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413069792, states[0] = -94.220283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423336197, states[0] = -94.221652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434171299, states[0] = -94.193744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444307328, states[0] = -94.191094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454396224, states[0] = -94.189532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464965967, states[0] = -94.182863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475180773, states[0] = -80.209736, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1486226742, states[0] = -94.205117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496496003, states[0] = -94.197065, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.058209
 - CaMKt in component CaMK (millimolar): 0.001715
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.090642
 - nass in component intracellular_ions (millimolar): 7.090780
 - ki in component intracellular_ions (millimolar): 144.601931
 - kss in component intracellular_ions (millimolar): 144.601917
 - cansr in component intracellular_ions (millimolar): 2.408580
 - cajsr in component intracellular_ions (millimolar): 2.408963
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003940
 - hf in component INa (dimensionless): 0.864573
 - hs in component INa (dimensionless): 0.864573
 - j in component INa (dimensionless): 0.864575
 - hsp in component INa (dimensionless): 0.697428
 - jp in component INa (dimensionless): 0.864576
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706371
 - hLp in component INaL (dimensionless): 0.512433
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998800
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005414
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001790
 - xs1 in component IKs (dimensionless): 0.023621
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997550
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:21:31 (41432): called boinc_finish(0)

</stderr_txt>
]]>


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