𝕏

Task 55650317

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846_0
Workunit 26426027
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 6:37:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 51 min 41 sec
CPU time 1 hours 41 min 29 sec
Validate state Valid
Credit 43.89
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.07 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846_0_r2071234227_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846_0_r2071234227_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.130310
     * GNaL_b in INaL: 0.005725
     * Gto_b in Ito: 0.086820
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032072
     * GKs_b in IKs: 0.001953
     * GK1_b in IK1: 0.166244
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.440053
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028831
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6752294, states[0] = -94.187772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17841989, states[0] = -94.053579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28551089, states[0] = -94.014104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39405816, states[0] = -93.902842, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846_0_r2071234227_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_846_0_r2071234227_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.130310
     * GNaL_b in INaL: 0.005725
     * Gto_b in Ito: 0.086820
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032072
     * GKs_b in IKs: 0.001953
     * GK1_b in IK1: 0.166244
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.440053
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028831
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 39405816
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.902842 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 49920683, states[0] = -93.972433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60232866, states[0] = -93.356613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70248499, states[0] = -93.979981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80018696, states[0] = -93.961241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90327957, states[0] = -93.747658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100392901, states[0] = -93.972278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110323460, states[0] = -93.955395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117132030, states[0] = -16.806978, states[40]= 0.001686
Saving checkpoint... 
Iteration: 127937645, states[0] = -93.959703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138262138, states[0] = -93.521084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147757959, states[0] = -93.989644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157828632, states[0] = -93.960991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167514060, states[0] = -93.952488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176366794, states[0] = -93.953759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186069811, states[0] = 17.899905, states[40]= 0.000861
Saving checkpoint... 
Iteration: 194187994, states[0] = -93.955568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203364320, states[0] = -93.953629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210774508, states[0] = -93.989267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220454600, states[0] = -93.968698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230379912, states[0] = -93.953380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238495055, states[0] = -93.967589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248748228, states[0] = -93.950334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259357188, states[0] = -93.971339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270176667, states[0] = -50.591955, states[40]= 0.000222
Saving checkpoint... 
Iteration: 280206646, states[0] = -93.976140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290122522, states[0] = -93.956083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297412139, states[0] = -93.883902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307939388, states[0] = -93.958594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318233238, states[0] = -93.343265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329066270, states[0] = -93.956740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339125090, states[0] = -11.141260, states[40]= 0.002263
Saving checkpoint... 
Iteration: 348931071, states[0] = -93.985911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358528447, states[0] = -93.966516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369139983, states[0] = -22.910226, states[40]= 0.002172
Saving checkpoint... 
Iteration: 379070175, states[0] = -93.980884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389089395, states[0] = -93.956331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399516258, states[0] = -93.954512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410825183, states[0] = -93.949526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417124112, states[0] = -10.358428, states[40]= 0.002393
Saving checkpoint... 
Iteration: 428021168, states[0] = -93.957187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438466706, states[0] = -93.929206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448123330, states[0] = -93.978809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458115885, states[0] = -93.955874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469142469, states[0] = -93.978078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479544998, states[0] = -93.951437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489623406, states[0] = -93.980623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499457661, states[0] = -93.968083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511046410, states[0] = -93.981542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521477210, states[0] = -93.951943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531518558, states[0] = -93.955196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542171970, states[0] = -93.955042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553255577, states[0] = -93.974013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563924298, states[0] = -93.948664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573706868, states[0] = -93.987252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583510935, states[0] = -93.966568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593398436, states[0] = -93.952541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603798354, states[0] = -93.988462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613974798, states[0] = -93.957539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624624100, states[0] = -93.980486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631232086, states[0] = -93.974666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642094846, states[0] = 7.480644, states[40]= 0.002602
Saving checkpoint... 
Iteration: 652683508, states[0] = -93.962544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663164525, states[0] = -41.121861, states[40]= 0.000800
Saving checkpoint... 
Iteration: 673601513, states[0] = -93.964268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684089276, states[0] = 9.991654, states[40]= 0.002133
Saving checkpoint... 
Iteration: 694377577, states[0] = -93.969983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703932851, states[0] = -93.958020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713685689, states[0] = -93.949957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723742665, states[0] = -93.988022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734420159, states[0] = -93.952098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744290868, states[0] = -93.634683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754200022, states[0] = -93.975557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763841361, states[0] = -93.959404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774358974, states[0] = -93.808845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784723644, states[0] = -93.961519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795854189, states[0] = -93.987298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806608153, states[0] = -93.950380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816680636, states[0] = -93.985493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827297259, states[0] = -93.953156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837040950, states[0] = 27.740019, states[40]= 0.000164
Saving checkpoint... 
Iteration: 847928058, states[0] = -93.957850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857760371, states[0] = -93.949193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868416500, states[0] = -93.968580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879791929, states[0] = -93.988035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889526484, states[0] = -93.965666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900032983, states[0] = 29.786453, states[40]= 0.000122
Saving checkpoint... 
Iteration: 910222059, states[0] = -93.974536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920896333, states[0] = -93.948225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931734859, states[0] = -93.961053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942794407, states[0] = -93.987916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952927893, states[0] = -93.957676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963465472, states[0] = -93.927527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973758207, states[0] = -93.960538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984217154, states[0] = -90.556492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990659273, states[0] = -93.983628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000639564, states[0] = -93.962878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011759660, states[0] = -93.987758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021899568, states[0] = -93.958005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031933775, states[0] = -93.947818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041728277, states[0] = -93.987175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052603820, states[0] = -93.949998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062715869, states[0] = -93.986766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073203361, states[0] = -93.953775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083600496, states[0] = -93.976171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093656603, states[0] = -93.962358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104241294, states[0] = -93.415590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114086926, states[0] = -93.979024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124822192, states[0] = -93.948337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131831384, states[0] = -93.987173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142303766, states[0] = -93.952555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153195204, states[0] = -93.975052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160191508, states[0] = -93.953766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170903982, states[0] = -93.985367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182137254, states[0] = -20.849897, states[40]= 0.001905
Saving checkpoint... 
Iteration: 1192610167, states[0] = -93.963198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202750273, states[0] = -93.948678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213066015, states[0] = -93.979632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223844515, states[0] = -93.948029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234721442, states[0] = -93.960802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245473387, states[0] = -93.931975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256833076, states[0] = -93.948045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267905872, states[0] = -93.957489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278690787, states[0] = -93.985307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289145156, states[0] = -93.954104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300050146, states[0] = -93.980073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311123331, states[0] = -9.736914, states[40]= 0.002500
Saving checkpoint... 
Iteration: 1322719137, states[0] = -93.948690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334217210, states[0] = -93.953175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344174925, states[0] = -49.216092, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1355077312, states[0] = -93.954857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365493254, states[0] = -93.942624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374591702, states[0] = -93.974108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385215867, states[0] = -93.953104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395988276, states[0] = -93.982178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407860764, states[0] = -93.986119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418785399, states[0] = -93.948078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426256334, states[0] = -93.972515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436813427, states[0] = -93.947866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447889094, states[0] = -93.957454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458224340, states[0] = -92.897040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469292057, states[0] = -93.952126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480847542, states[0] = -93.958088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492312594, states[0] = -93.970596, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.822635
 - CaMKt in component CaMK (millimolar): 0.001332
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.653884
 - nass in component intracellular_ions (millimolar): 6.654010
 - ki in component intracellular_ions (millimolar): 145.207777
 - kss in component intracellular_ions (millimolar): 145.207768
 - cansr in component intracellular_ions (millimolar): 1.842986
 - cajsr in component intracellular_ions (millimolar): 1.842845
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.004035
 - hf in component INa (dimensionless): 0.859976
 - hs in component INa (dimensionless): 0.859977
 - j in component INa (dimensionless): 0.859978
 - hsp in component INa (dimensionless): 0.689197
 - jp in component INa (dimensionless): 0.859979
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699795
 - hLp in component INaL (dimensionless): 0.504613
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999230
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999701
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999520
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005593
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000579
 - xs1 in component IKs (dimensionless): 0.014764
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997606
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:29:07 (41435): called boinc_finish(0)

</stderr_txt>
]]>


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