𝕏

Task 55650316

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_746_1
Workunit 26426026
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 3 Jul 2024, 9:21:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 50 min 4 sec
CPU time 1 hours 41 min 45 sec
Validate state Valid
Credit 44.56
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_746.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_746_1_r988490437_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_746_1_r988490437_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.325444
     * GNaL_b in INaL: 0.006034
     * Gto_b in Ito: 0.086335
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031847
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.164107
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256951
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031984
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7181140, states[0] = -94.104155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18407777, states[0] = -93.914598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29134547, states[0] = -93.936142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39346239, states[0] = -93.747671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50444062, states[0] = -93.901320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57796210, states[0] = -93.934330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67468993, states[0] = -93.910820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74558574, states[0] = -93.893255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81631092, states[0] = -93.923458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92494974, states[0] = -93.892475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103300040, states[0] = -93.913127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113645968, states[0] = -93.890667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123857146, states[0] = -93.928147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134830218, states[0] = -93.889124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145756668, states[0] = -93.901100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156747217, states[0] = -93.928708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167040257, states[0] = -93.896374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177526940, states[0] = -93.898493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187848952, states[0] = -93.899231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200052348, states[0] = -93.896088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210530890, states[0] = -93.899792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221109408, states[0] = -93.895280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229033038, states[0] = -93.921787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239274625, states[0] = -93.893298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250472764, states[0] = -93.907126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261094407, states[0] = 7.856564, states[40]= 0.002898
Saving checkpoint... 
Iteration: 271963042, states[0] = -93.897210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279530735, states[0] = -93.899598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289325792, states[0] = -93.911292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299309938, states[0] = -93.892814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306681869, states[0] = -93.925996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317830632, states[0] = -93.888549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324670167, states[0] = -93.925182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335507666, states[0] = -93.890890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346601682, states[0] = -93.903794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357666838, states[0] = -93.924880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367769782, states[0] = -93.900291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377827451, states[0] = -93.888471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387655767, states[0] = -93.923919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398663485, states[0] = -93.889553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408205783, states[0] = -75.084368, states[40]= 0.000004
Saving checkpoint... 
Iteration: 419156992, states[0] = -93.894339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429958685, states[0] = -93.924182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440350893, states[0] = -93.892166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450787810, states[0] = -93.928269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460787550, states[0] = -93.899811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471194900, states[0] = -64.121488, states[40]= 0.000027
Saving checkpoint... 
Iteration: 482184060, states[0] = -93.893912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493344436, states[0] = -93.910381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503794497, states[0] = -93.888478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514719300, states[0] = -93.901024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525410140, states[0] = -93.820233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536052541, states[0] = -93.895496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546613555, states[0] = -93.918744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557110232, states[0] = -93.894700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568096568, states[0] = -93.918818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578825394, states[0] = -93.888158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589787880, states[0] = -93.899597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600086556, states[0] = 11.338870, states[40]= 0.002211
Saving checkpoint... 
Iteration: 610197205, states[0] = -93.915062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620879588, states[0] = -93.887756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631384714, states[0] = -93.908952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642549883, states[0] = -93.905094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652892263, states[0] = -93.897694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663787831, states[0] = -93.927926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674237940, states[0] = -93.892981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684589695, states[0] = -93.914486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695157580, states[0] = -93.893886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705697941, states[0] = -93.926219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716001259, states[0] = -93.895923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726741669, states[0] = -93.927555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737530009, states[0] = -93.890050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748798204, states[0] = -93.899152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759623569, states[0] = -93.919801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770503341, states[0] = -93.890222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781334666, states[0] = -93.910217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791527413, states[0] = -93.889985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802203237, states[0] = -93.914539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812577931, states[0] = -93.889538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822769692, states[0] = -93.927680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833418836, states[0] = -93.890876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843510437, states[0] = -93.890860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853999866, states[0] = -93.895720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864618084, states[0] = -93.918885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874938170, states[0] = -93.896608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885557672, states[0] = -93.906866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896403057, states[0] = -93.890922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907146768, states[0] = -93.916403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914190615, states[0] = -93.893136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925247648, states[0] = -93.912806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936091406, states[0] = 9.221935, states[40]= 0.002634
Saving checkpoint... 
Iteration: 946209450, states[0] = -93.914089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956531283, states[0] = -93.889685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966945133, states[0] = -93.923789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976866660, states[0] = -93.897592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987916409, states[0] = -93.924712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998604180, states[0] = -93.889031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008419148, states[0] = -93.828944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015046261, states[0] = -93.919999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025083857, states[0] = -93.894286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035543888, states[0] = -93.902677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046458090, states[0] = -93.890173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056216582, states[0] = -88.471033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066743336, states[0] = -93.899663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075510748, states[0] = -93.904798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085495588, states[0] = -93.889780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095717670, states[0] = -93.926371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106073410, states[0] = -93.894293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115610057, states[0] = -93.888796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125978896, states[0] = -93.922334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135605518, states[0] = -93.902432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146251792, states[0] = -93.406290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156433777, states[0] = -93.906706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167219887, states[0] = -90.926397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178035547, states[0] = -93.894692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188917100, states[0] = -93.924366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199176356, states[0] = -93.892844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209710434, states[0] = -93.925935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220752485, states[0] = -93.887596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230862175, states[0] = -93.925867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241409573, states[0] = -93.890302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251526736, states[0] = -93.896603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262158509, states[0] = -93.892957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269318009, states[0] = -93.654898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278955621, states[0] = -93.922921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289566586, states[0] = -93.888858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299953718, states[0] = -93.922954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310550476, states[0] = -93.888954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321569660, states[0] = -93.902960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332252844, states[0] = -93.411073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342711743, states[0] = -93.899837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353126885, states[0] = -12.249008, states[40]= 0.002201
Saving checkpoint... 
Iteration: 1363801217, states[0] = -93.898104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374021104, states[0] = 31.623663, states[40]= 0.001324
Saving checkpoint... 
Iteration: 1384745267, states[0] = -93.899111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395314066, states[0] = -93.643767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405435077, states[0] = -93.906268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412231410, states[0] = -93.891861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423209483, states[0] = -93.913318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434065906, states[0] = 19.488536, states[40]= 0.000848
Saving checkpoint... 
Iteration: 1444707615, states[0] = -93.899754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455068193, states[0] = 18.641653, states[40]= 0.000956
Saving checkpoint... 
Iteration: 1465573718, states[0] = -93.902632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475463800, states[0] = -93.889428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485636087, states[0] = -93.920166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496966801, states[0] = -93.885834, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.761626
 - CaMKt in component CaMK (millimolar): 0.001329
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.703930
 - nass in component intracellular_ions (millimolar): 6.704055
 - ki in component intracellular_ions (millimolar): 145.158774
 - kss in component intracellular_ions (millimolar): 145.158764
 - cansr in component intracellular_ions (millimolar): 1.840811
 - cajsr in component intracellular_ions (millimolar): 1.840686
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004060
 - hf in component INa (dimensionless): 0.858765
 - hs in component INa (dimensionless): 0.858765
 - j in component INa (dimensionless): 0.858766
 - hsp in component INa (dimensionless): 0.687046
 - jp in component INa (dimensionless): 0.858767
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.698080
 - hLp in component INaL (dimensionless): 0.502576
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.999221
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999697
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999517
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005567
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000592
 - xs1 in component IKs (dimensionless): 0.014825
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997621
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:10:49 (24486): called boinc_finish(0)

</stderr_txt>
]]>


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