𝕏

Task 55650314

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646_1
Workunit 26426025
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 5:07:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 53 min 14 sec
CPU time 1 hours 42 min 28 sec
Validate state Valid
Credit 43.52
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.90 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646_1_r617870141_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646_1_r617870141_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.956880
     * GNaL_b in INaL: 0.005553
     * Gto_b in Ito: 0.087312
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032318
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.161367
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.194438
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031549
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7397264, states[0] = -94.106561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17384346, states[0] = -93.994018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27474411, states[0] = -93.920691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38027133, states[0] = -93.917409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47162373, states[0] = -93.904320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56983882, states[0] = -93.891147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67014694, states[0] = -93.922278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77626678, states[0] = -93.887729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87852740, states[0] = -93.924447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98078309, states[0] = -93.891291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108567638, states[0] = -93.906009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119152759, states[0] = -93.889398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129619081, states[0] = -93.914945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140296469, states[0] = -93.887256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151029572, states[0] = -93.916203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160832356, states[0] = -93.893332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167115920, states[0] = -93.889015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178146955, states[0] = -93.911467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188443082, states[0] = -93.885313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199087325, states[0] = -93.913598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205411095, states[0] = -93.902565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215699235, states[0] = -93.883118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226349278, states[0] = -93.904328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236595486, states[0] = -93.883829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247438562, states[0] = -93.901655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257471420, states[0] = -93.884815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267380130, states[0] = -93.775997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277707055, states[0] = -93.895190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288768687, states[0] = -93.922465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299024693, states[0] = -93.889759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309094797, states[0] = 7.283020, states[40]= 0.002937
Saving checkpoint... 
Iteration: 319493470, states[0] = -93.900034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329268423, states[0] = -93.886678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339805898, states[0] = -93.922214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349546412, states[0] = -93.898645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360108055, states[0] = 0.307671, states[40]= 0.003738
Saving checkpoint... 
Iteration: 369939993, states[0] = -93.918739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380628512, states[0] = -93.883302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391650081, states[0] = -93.896188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401622534, states[0] = -93.883313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412507710, states[0] = -93.899513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422906491, states[0] = -93.881367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433091995, states[0] = -93.912931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443463367, states[0] = -93.884565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452841172, states[0] = -93.881716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463144548, states[0] = -93.910897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472383256, states[0] = -93.902853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482691539, states[0] = -93.882671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492538630, states[0] = -93.895853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503775920, states[0] = -93.882055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514079765, states[0] = -93.913270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524139188, states[0] = -93.887871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534406462, states[0] = -93.809802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545127094, states[0] = -93.887989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555448449, states[0] = -93.849315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565929890, states[0] = -93.890737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576479637, states[0] = -93.869986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583972161, states[0] = -93.890060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593716850, states[0] = -93.882314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604346625, states[0] = -93.903751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614229270, states[0] = -93.886655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624243878, states[0] = -93.357483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634290081, states[0] = -93.905505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644411143, states[0] = -93.884724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653804330, states[0] = -93.881629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663953635, states[0] = -93.917790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674860791, states[0] = -93.881239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684533757, states[0] = -93.893932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694554556, states[0] = -93.897894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705220509, states[0] = -92.240087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715596496, states[0] = -93.896868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725551929, states[0] = -93.883355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736145591, states[0] = -93.910423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746743874, states[0] = -93.881883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756785800, states[0] = -93.921701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765054790, states[0] = 23.232369, states[40]= 0.000471
Saving checkpoint... 
Iteration: 775562132, states[0] = -93.897582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785617989, states[0] = -93.882734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795250033, states[0] = -93.389191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805045290, states[0] = -93.914130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815173836, states[0] = -93.886981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825823792, states[0] = -93.921192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836402826, states[0] = -93.884495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847322072, states[0] = -93.904132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857823658, states[0] = -93.881179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868667442, states[0] = -93.895053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878823715, states[0] = -93.881145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887802836, states[0] = -93.881265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894642116, states[0] = -93.915762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904586460, states[0] = -93.896799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915208649, states[0] = -82.645444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923248738, states[0] = -93.885942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932722370, states[0] = -93.881734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942670448, states[0] = -93.918183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953018984, states[0] = -93.888788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963501672, states[0] = -93.880714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974291101, states[0] = -93.885399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983948829, states[0] = -93.880225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994001722, states[0] = -93.915491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004136936, states[0] = -93.887132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014296482, states[0] = -93.582992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024503000, states[0] = -93.898657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034096508, states[0] = -93.887601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044230139, states[0] = -93.208935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054488114, states[0] = -93.898996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064663328, states[0] = -93.881946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075171703, states[0] = -93.908919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085461490, states[0] = -93.883556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095807523, states[0] = -93.920990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106327685, states[0] = -93.884806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116522307, states[0] = -93.889133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127254596, states[0] = -93.885551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137511358, states[0] = -93.884717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147447073, states[0] = -93.899951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158395834, states[0] = -93.796014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168204606, states[0] = -93.907582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175448971, states[0] = -93.883525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185649721, states[0] = -93.916063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196303251, states[0] = -93.884916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206570696, states[0] = -93.903594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216871952, states[0] = -93.890636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227197184, states[0] = -69.130775, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1237386735, states[0] = -93.901529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247480973, states[0] = -93.883124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256883776, states[0] = -93.880169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263248270, states[0] = -93.379552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273557223, states[0] = -93.896905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283865539, states[0] = -93.880237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293651026, states[0] = -93.916015, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646_1_r617870141_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_646_1_r617870141_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.956880
     * GNaL_b in INaL: 0.005553
     * Gto_b in Ito: 0.087312
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032318
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.161367
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.194438
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031549
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1293651026
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.916015 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1303163723, states[0] = -93.908848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314098278, states[0] = 5.593623, states[40]= 0.003222
Saving checkpoint... 
Iteration: 1324031718, states[0] = -93.913823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334685782, states[0] = -93.881351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345167342, states[0] = -93.908648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355556001, states[0] = -93.882315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365930784, states[0] = -93.917468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373388913, states[0] = -93.883770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383542018, states[0] = -93.895511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393855147, states[0] = -93.890637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404194628, states[0] = -66.696857, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1413779129, states[0] = -93.920672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424073791, states[0] = -93.887279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434713523, states[0] = -93.919654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444214132, states[0] = -93.906804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453797673, states[0] = -93.891556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464313001, states[0] = -93.633743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471247645, states[0] = -93.905594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481642703, states[0] = -93.881433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492013397, states[0] = -93.914255, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.755095
 - CaMKt in component CaMK (millimolar): 0.001313
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.660373
 - nass in component intracellular_ions (millimolar): 6.660497
 - ki in component intracellular_ions (millimolar): 145.204456
 - kss in component intracellular_ions (millimolar): 145.204447
 - cansr in component intracellular_ions (millimolar): 1.831005
 - cajsr in component intracellular_ions (millimolar): 1.830890
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004063
 - hf in component INa (dimensionless): 0.858635
 - hs in component INa (dimensionless): 0.858635
 - j in component INa (dimensionless): 0.858636
 - hsp in component INa (dimensionless): 0.686815
 - jp in component INa (dimensionless): 0.858637
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697897
 - hLp in component INaL (dimensionless): 0.502359
 - a in component Ito (dimensionless): 0.000674
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.999225
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999698
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999524
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005452
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000589
 - xs1 in component IKs (dimensionless): 0.014666
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997622
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:21:46 (41428): called boinc_finish(0)

</stderr_txt>
]]>


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