𝕏

Task 55650308

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_446_1
Workunit 26426022
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 3 Jul 2024, 11:30:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 53 min 18 sec
CPU time 1 hours 42 min 27 sec
Validate state Valid
Credit 41.44
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_446.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_446_1_r722643038_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_6000-conf_446_1_r722643038_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.409233
     * GNaL_b in INaL: 0.005670
     * Gto_b in Ito: 0.085786
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.168166
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.222490
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030538
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7097659, states[0] = -94.155258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17669150, states[0] = -94.035861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27949674, states[0] = -94.015272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38088948, states[0] = -93.967188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48483770, states[0] = -93.938934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59501546, states[0] = -93.946338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70227066, states[0] = -93.966367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80233383, states[0] = -93.944956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90711386, states[0] = -93.976559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100710995, states[0] = -93.951348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110010454, states[0] = -93.946132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121189999, states[0] = -93.964587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131275882, states[0] = -93.942509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141247874, states[0] = -93.449685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151829196, states[0] = -93.948255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162198337, states[0] = -68.682737, states[40]= 0.000012
Saving checkpoint... 
Iteration: 172759241, states[0] = -93.949342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183061100, states[0] = 21.049960, states[40]= 0.000544
Saving checkpoint... 
Iteration: 189887274, states[0] = -93.974398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199304884, states[0] = -93.960183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209658028, states[0] = -93.938658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219378845, states[0] = -93.831432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229397986, states[0] = -93.957362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239043462, states[0] = -93.944654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249493743, states[0] = -93.932284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259283222, states[0] = -93.960703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269547716, states[0] = -93.939351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279769107, states[0] = -93.975834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289362637, states[0] = -93.958242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299913285, states[0] = -93.936825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309625195, states[0] = -93.968059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319808246, states[0] = -93.948082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326520206, states[0] = -93.939469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336136408, states[0] = -20.304470, states[40]= 0.001850
Saving checkpoint... 
Iteration: 346816919, states[0] = -93.947886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357489805, states[0] = -93.930138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367984690, states[0] = -93.945225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377838217, states[0] = -93.937131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387409176, states[0] = -93.869156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398041015, states[0] = -93.944396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408479456, states[0] = -93.924570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417545623, states[0] = -93.951843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428287031, states[0] = -93.941446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439567986, states[0] = -93.952676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449566696, states[0] = -93.938888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459186254, states[0] = -58.070315, states[40]= 0.000069
Saving checkpoint... 
Iteration: 469320105, states[0] = -93.959196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479037592, states[0] = -93.944306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489058045, states[0] = 22.142219, states[40]= 0.000457
Saving checkpoint... 
Iteration: 495793493, states[0] = -93.975451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505500033, states[0] = -93.954184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512180224, states[0] = -93.942472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522056689, states[0] = 22.618652, states[40]= 0.000423
Saving checkpoint... 
Iteration: 529383999, states[0] = -93.957221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539249830, states[0] = -93.941651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549544579, states[0] = -93.951313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560134240, states[0] = -93.942935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570190822, states[0] = -61.819758, states[40]= 0.000037
Saving checkpoint... 
Iteration: 579986864, states[0] = -93.970483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590051693, states[0] = -93.943931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599358926, states[0] = -93.940441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608236894, states[0] = -93.941675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618015364, states[0] = 31.571615, states[40]= 0.009270
Saving checkpoint... 
Iteration: 627532677, states[0] = -93.947425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637571432, states[0] = -93.952264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647827729, states[0] = -93.936740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655563291, states[0] = -93.952420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666091286, states[0] = 9.012556, states[40]= 0.002328
Saving checkpoint... 
Iteration: 675349704, states[0] = -93.781833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685056215, states[0] = -93.967814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695308753, states[0] = -93.940774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706302528, states[0] = -93.959336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717170134, states[0] = -45.409101, states[40]= 0.000462
Saving checkpoint... 
Iteration: 724046366, states[0] = -93.968107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730858294, states[0] = -93.946545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741568402, states[0] = -93.957303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751396516, states[0] = -93.956496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761870641, states[0] = -93.936290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772173502, states[0] = -93.963470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783090106, states[0] = 9.537449, states[40]= 0.002229
Saving checkpoint... 
Iteration: 793647389, states[0] = -93.950344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804790501, states[0] = -93.974947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815032867, states[0] = -93.943804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825495349, states[0] = -93.932073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835333868, states[0] = -93.958166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845444363, states[0] = -93.939239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856203422, states[0] = -93.962301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866658068, states[0] = -93.937500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876640276, states[0] = -93.968863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886846166, states[0] = -93.946483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896404726, states[0] = -93.939510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903399584, states[0] = -93.857428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913272859, states[0] = -93.959919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923266522, states[0] = -93.940827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933303826, states[0] = -93.669399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942634186, states[0] = -93.968080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953185763, states[0] = -93.941666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963297669, states[0] = -93.650039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973268329, states[0] = -93.959963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983934299, states[0] = -93.935550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994673948, states[0] = -93.949461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004921266, states[0] = -93.935588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015103159, states[0] = -93.965557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026016425, states[0] = 31.654481, states[40]= 0.006422
Saving checkpoint... 
Iteration: 1036014154, states[0] = -93.968747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046405441, states[0] = -93.939251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055986991, states[0] = -93.935142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066710733, states[0] = -93.948611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076947114, states[0] = -93.935323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087423644, states[0] = -93.955185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098088326, states[0] = 10.317938, states[40]= 0.002082
Saving checkpoint... 
Iteration: 1108513290, states[0] = -93.952844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119421434, states[0] = -93.880424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129971052, states[0] = -93.944138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140228686, states[0] = -93.226012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150675236, states[0] = -93.949172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160837012, states[0] = -93.935820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171550413, states[0] = -93.951851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181293602, states[0] = -93.940111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191561922, states[0] = -93.954977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202079023, states[0] = -93.942544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212490688, states[0] = -93.929143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223308960, states[0] = -93.939883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232882348, states[0] = -93.935428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243433470, states[0] = -93.954658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253986403, states[0] = -93.934811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264750323, states[0] = -93.947528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275767704, states[0] = -93.974149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285700599, states[0] = -93.948441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296551044, states[0] = -93.951922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306420892, states[0] = -93.954891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317571671, states[0] = -93.957091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324413811, states[0] = -93.955054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335464980, states[0] = -93.914387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345961817, states[0] = -93.943909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356357359, states[0] = -93.794875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366770543, states[0] = -93.946986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376498585, states[0] = -93.937879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386535595, states[0] = -93.947112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396576025, states[0] = -93.950883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407372327, states[0] = -93.819644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418221466, states[0] = -93.940481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428399771, states[0] = -93.856763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438518932, states[0] = -93.952152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449112866, states[0] = -2.311444, states[40]= 0.003504
Saving checkpoint... 
Iteration: 1459431109, states[0] = -93.954358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468946202, states[0] = -93.943932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479554844, states[0] = -93.952656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489661365, states[0] = -93.948885, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.810304
 - CaMKt in component CaMK (millimolar): 0.001330
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.683917
 - nass in component intracellular_ions (millimolar): 6.684043
 - ki in component intracellular_ions (millimolar): 145.178166
 - kss in component intracellular_ions (millimolar): 145.178156
 - cansr in component intracellular_ions (millimolar): 1.841216
 - cajsr in component intracellular_ions (millimolar): 1.841087
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004040
 - hf in component INa (dimensionless): 0.859732
 - hs in component INa (dimensionless): 0.859732
 - j in component INa (dimensionless): 0.859734
 - hsp in component INa (dimensionless): 0.688763
 - jp in component INa (dimensionless): 0.859734
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699448
 - hLp in component INaL (dimensionless): 0.504200
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999842
 - iS in component Ito (dimensionless): 0.999228
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999842
 - iSp in component Ito (dimensionless): 0.999700
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999521
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005573
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000582
 - xs1 in component IKs (dimensionless): 0.014745
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997609
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:03:29 (26193): called boinc_finish(0)

</stderr_txt>
]]>


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