𝕏

Task 55650263

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246_0
Workunit 26426000
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 6:37:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 51 min 35 sec
CPU time 1 hours 42 min 30 sec
Validate state Valid
Credit 44.58
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.05 MB
Peak swap size 32.91 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246_0_r1777402883_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246_0_r1777402883_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.647188
     * GNaL_b in INaL: 0.005440
     * Gto_b in Ito: 0.083347
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032348
     * GKs_b in IKs: 0.001964
     * GK1_b in IK1: 0.166929
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.179719
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031272
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6747546, states[0] = -94.154549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17018173, states[0] = -94.059804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27757680, states[0] = -93.996770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38282052, states[0] = -93.653902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48765780, states[0] = -93.999300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59459106, states[0] = -93.974485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69284309, states[0] = -93.978708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80241356, states[0] = -93.458602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89613507, states[0] = -93.968723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100690321, states[0] = -93.993196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111380999, states[0] = -93.974809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122160156, states[0] = -41.827830, states[40]= 0.000670
Saving checkpoint... 
Iteration: 130606850, states[0] = -93.985679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140604496, states[0] = -93.985317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150962766, states[0] = -93.989840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160923778, states[0] = -93.991223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167797577, states[0] = -93.964598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179111518, states[0] = -93.984039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189563744, states[0] = -93.969634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199943306, states[0] = -93.961968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210071576, states[0] = 16.405671, states[40]= 0.001192
Saving checkpoint... 
Iteration: 220630414, states[0] = -93.988463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231434957, states[0] = -93.972969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241680707, states[0] = -93.966806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251376043, states[0] = -93.974664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261903106, states[0] = -93.962491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272783762, states[0] = -93.994304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283004126, states[0] = -93.987975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293912665, states[0] = -93.962254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304676486, states[0] = -93.992027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315109396, states[0] = -93.983806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325385315, states[0] = -93.974207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336553953, states[0] = -93.974902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346728393, states[0] = -93.993844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356917276, states[0] = -93.990994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366218339, states[0] = -92.959616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376967502, states[0] = -93.989144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387536574, states[0] = -93.969850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398665268, states[0] = -93.991098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410515223, states[0] = -93.962702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417844939, states[0] = -93.963136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428239795, states[0] = -93.449247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438204118, states[0] = -83.662539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448088918, states[0] = 9.058666, states[40]= 0.002493
Saving checkpoint... 
Iteration: 458679686, states[0] = -93.991840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468834278, states[0] = -93.993100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479458669, states[0] = -93.971709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490158883, states[0] = -40.818705, states[40]= 0.000759
Saving checkpoint... 
Iteration: 500653242, states[0] = -93.989959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507198938, states[0] = -93.979987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514160407, states[0] = -42.028512, states[40]= 0.000653
Saving checkpoint... 
Iteration: 525126144, states[0] = -93.982662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535128262, states[0] = -93.982557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545921822, states[0] = -93.961499, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246_0_r1777402883_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_246_0_r1777402883_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.647188
     * GNaL_b in INaL: 0.005440
     * Gto_b in Ito: 0.083347
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032348
     * GKs_b in IKs: 0.001964
     * GK1_b in IK1: 0.166929
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.179719
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031272
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 545921822
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.961499 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 555485620, states[0] = -93.970788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565418207, states[0] = -93.972657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575843397, states[0] = -93.962787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586354106, states[0] = -93.818669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597050010, states[0] = -93.985442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607329559, states[0] = -93.975272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617646608, states[0] = -93.966662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624478697, states[0] = -93.945834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634959899, states[0] = -93.988812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644847636, states[0] = -93.992376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654993346, states[0] = -93.987503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665366948, states[0] = -93.973956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675765290, states[0] = -93.964022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685355625, states[0] = -93.974260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695871399, states[0] = -93.962001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704484876, states[0] = -93.948828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714849367, states[0] = -93.992167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722065504, states[0] = 18.758781, states[40]= 0.000875
Saving checkpoint... 
Iteration: 731907705, states[0] = -93.961291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742980735, states[0] = -93.987774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752443253, states[0] = -93.923148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762626685, states[0] = -93.986759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772926245, states[0] = -93.989694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783357788, states[0] = -93.973959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793400917, states[0] = -93.972622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803998889, states[0] = -93.959654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811169761, states[0] = -93.980335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822193774, states[0] = -70.535904, states[40]= 0.000008
Saving checkpoint... 
Iteration: 832479821, states[0] = -93.945931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842388422, states[0] = -93.869330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852875204, states[0] = -93.991144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862900635, states[0] = -93.990340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873392472, states[0] = -93.972683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883786677, states[0] = -93.963109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894299719, states[0] = -93.690646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904194101, states[0] = -70.889857, states[40]= 0.000008
Saving checkpoint... 
Iteration: 914230632, states[0] = -93.391010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925515587, states[0] = -93.969108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932805929, states[0] = -93.992500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943306893, states[0] = -93.975206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953369600, states[0] = -93.973187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964179550, states[0] = -57.538858, states[40]= 0.000069
Saving checkpoint... 
Iteration: 974394661, states[0] = -93.876629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985010883, states[0] = -93.986040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995329123, states[0] = -93.974360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005206655, states[0] = -93.978519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015349269, states[0] = -93.973672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026114363, states[0] = -5.445633, states[40]= 0.003267
Saving checkpoint... 
Iteration: 1036058603, states[0] = 21.320986, states[40]= 0.000602
Saving checkpoint... 
Iteration: 1046316066, states[0] = -93.736081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056623554, states[0] = -93.985694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067368164, states[0] = -93.972959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077521609, states[0] = -93.968588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087723803, states[0] = -93.963875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097837413, states[0] = -93.961648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108743316, states[0] = -93.992251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119076698, states[0] = -93.983155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128911605, states[0] = -93.989345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139768177, states[0] = -93.962857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147273422, states[0] = -93.975838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157476582, states[0] = -93.969596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168268427, states[0] = -93.578800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178955938, states[0] = -93.987662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189644475, states[0] = -93.965344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199955038, states[0] = -93.959394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210379053, states[0] = -93.856109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220713863, states[0] = -93.991419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230948795, states[0] = -93.987799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241646753, states[0] = -93.965169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252663844, states[0] = -93.988966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262705753, states[0] = -93.991068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273002243, states[0] = -93.985687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283230146, states[0] = -93.977016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294341520, states[0] = -93.793358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304869421, states[0] = -93.990232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315551054, states[0] = -93.967268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325705151, states[0] = -93.963695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335906434, states[0] = -93.959869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346288473, states[0] = -93.653393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356587758, states[0] = -93.979720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366365659, states[0] = -93.836016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376271130, states[0] = -93.589236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387001607, states[0] = -93.985440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397340457, states[0] = -93.973038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407261281, states[0] = -93.975633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417773423, states[0] = -93.962090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428087769, states[0] = 9.583670, states[40]= 0.002394
Saving checkpoint... 
Iteration: 1438320195, states[0] = -93.745557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448072750, states[0] = 15.940753, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1458846539, states[0] = -93.990462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469473164, states[0] = -93.968944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479606496, states[0] = -93.965527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490126386, states[0] = -15.257363, states[40]= 0.001745
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.833943
 - CaMKt in component CaMK (millimolar): 0.002076
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.757872
 - nass in component intracellular_ions (millimolar): 6.757995
 - ki in component intracellular_ions (millimolar): 145.100380
 - kss in component intracellular_ions (millimolar): 145.100370
 - cansr in component intracellular_ions (millimolar): 1.834527
 - cajsr in component intracellular_ions (millimolar): 1.834380
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004030
 - hf in component INa (dimensionless): 0.860200
 - hs in component INa (dimensionless): 0.860201
 - j in component INa (dimensionless): 0.860205
 - hsp in component INa (dimensionless): 0.689598
 - jp in component INa (dimensionless): 0.860207
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700144
 - hLp in component INaL (dimensionless): 0.504487
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.991490
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.996597
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996518
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005285
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008017
 - xs1 in component IKs (dimensionless): 0.040826
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997604
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:37:42 (41430): called boinc_finish(0)

</stderr_txt>
]]>


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