𝕏

Task 55650261

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_146_0
Workunit 26425999
Created 1 Jul 2024, 15:53:51 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 3 Jul 2024, 10:23:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 53 min 24 sec
CPU time 1 hours 42 min 49 sec
Validate state Valid
Credit 44.94
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_146.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_146_0_r64486208_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_4000-conf_146_0_r64486208_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.703147
     * GNaL_b in INaL: 0.005859
     * Gto_b in Ito: 0.083853
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032273
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.159823
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.919851
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034056
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7627891, states[0] = -94.096518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14494169, states[0] = -94.006077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24452601, states[0] = -93.926315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35144051, states[0] = -93.950804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45963158, states[0] = -93.917332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56287150, states[0] = -93.588627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66482904, states[0] = -93.897308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76277238, states[0] = -93.545936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86853384, states[0] = -93.941223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96756425, states[0] = -93.942170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106505239, states[0] = -93.905274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117267878, states[0] = -93.924167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129192534, states[0] = -93.926802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139662401, states[0] = -93.912175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150203434, states[0] = -78.891368, states[40]= 0.000002
Saving checkpoint... 
Iteration: 157140060, states[0] = -93.928587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167908027, states[0] = -93.906897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178831374, states[0] = -93.940143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189169271, states[0] = -93.927228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200164008, states[0] = -43.405816, states[40]= 0.000568
Saving checkpoint... 
Iteration: 207311127, states[0] = -93.921865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217887496, states[0] = -93.907041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226955774, states[0] = -93.935836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234192524, states[0] = -66.847993, states[40]= 0.000015
Saving checkpoint... 
Iteration: 244525142, states[0] = -93.911936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251475255, states[0] = -93.916497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261662167, states[0] = -93.911583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272018329, states[0] = 31.698372, states[40]= 0.003317
Saving checkpoint... 
Iteration: 281898878, states[0] = -93.906651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292593882, states[0] = -93.929330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303211498, states[0] = -93.925235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313554682, states[0] = -93.914133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324173060, states[0] = -50.640018, states[40]= 0.000208
Saving checkpoint... 
Iteration: 334992895, states[0] = -93.934056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345061253, states[0] = -93.931192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354230201, states[0] = -93.277899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363833511, states[0] = -93.907674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374716162, states[0] = -93.939839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384968452, states[0] = -93.934929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395783147, states[0] = -93.908601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406426825, states[0] = -93.853373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416561010, states[0] = -93.922186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426363974, states[0] = -93.774359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437121288, states[0] = -93.928491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447723362, states[0] = -93.909743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457819737, states[0] = -93.907719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469124941, states[0] = -93.928266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479197690, states[0] = -93.925346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489144429, states[0] = -93.927429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500523995, states[0] = -93.910904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510944112, states[0] = -93.935592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521244589, states[0] = -93.923466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530812752, states[0] = -93.939585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541728891, states[0] = -93.909399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551755413, states[0] = -93.908807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561809073, states[0] = -93.907683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572805804, states[0] = -93.939603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582241978, states[0] = -93.379284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592303715, states[0] = -93.634936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602597093, states[0] = -93.929139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612982444, states[0] = -93.933824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622576440, states[0] = -93.925212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633176474, states[0] = -93.925810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643178793, states[0] = -93.925695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653422370, states[0] = -93.917111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663780785, states[0] = -93.908013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673813360, states[0] = -93.907332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684501132, states[0] = -93.901285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694872845, states[0] = -93.937685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705107238, states[0] = -93.928432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715442199, states[0] = -93.916360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725372061, states[0] = -93.918535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735798992, states[0] = -93.907472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746281648, states[0] = -93.558711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757023860, states[0] = -93.931774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767823870, states[0] = -93.906902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778986525, states[0] = -93.933264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789907266, states[0] = -93.905288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799381320, states[0] = -93.918060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808645442, states[0] = -93.934819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818099028, states[0] = 4.657785, states[40]= 0.003351
Saving checkpoint... 
Iteration: 825281568, states[0] = -93.921395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835747520, states[0] = -93.908301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845187423, states[0] = -93.924878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855267862, states[0] = -93.921819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864330510, states[0] = -93.706538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874573449, states[0] = -93.923978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884275448, states[0] = -93.534022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894825727, states[0] = -93.938468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905489794, states[0] = -93.914512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916275579, states[0] = -93.534473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923043268, states[0] = -93.930572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933366765, states[0] = -93.918215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943723821, states[0] = -93.908556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953441432, states[0] = -93.915818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963026249, states[0] = -93.931187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972890396, states[0] = -93.936459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981254492, states[0] = -93.922009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990887908, states[0] = -93.936499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001087442, states[0] = -93.928548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011417271, states[0] = -93.916420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022338212, states[0] = -93.723566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032521984, states[0] = -93.908916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043027045, states[0] = -93.930965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052257650, states[0] = -93.456072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062327966, states[0] = -93.700011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073027068, states[0] = -93.930893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083563151, states[0] = -93.912080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094005617, states[0] = 31.004522, states[40]= 0.268208
Saving checkpoint... 
Iteration: 1103004617, states[0] = -93.931753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113084771, states[0] = -93.928393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123399613, states[0] = -93.916707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133584503, states[0] = -93.911408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143403532, states[0] = -93.916536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153634340, states[0] = -93.910118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163842456, states[0] = -93.905601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170599147, states[0] = -93.928135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180945257, states[0] = -93.933962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191072581, states[0] = -93.928715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201925616, states[0] = -93.903985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212055076, states[0] = 22.855423, states[40]= 0.000503
Saving checkpoint... 
Iteration: 1222991992, states[0] = -93.931989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233609615, states[0] = -93.910536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244129982, states[0] = -17.121738, states[40]= 0.001686
Saving checkpoint... 
Iteration: 1254985410, states[0] = -93.932183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264882005, states[0] = -93.936045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275350177, states[0] = -93.917953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285346117, states[0] = -93.918065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294346023, states[0] = -93.739245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303407078, states[0] = -93.916045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309886849, states[0] = -93.904423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320191514, states[0] = -65.907407, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1329871724, states[0] = -93.904655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340797998, states[0] = -93.937900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349938882, states[0] = -93.903403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359829513, states[0] = -93.905386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370106859, states[0] = 0.327262, states[40]= 0.003726
Saving checkpoint... 
Iteration: 1380003080, states[0] = 38.201174, states[40]= 0.628212
Saving checkpoint... 
Iteration: 1390188460, states[0] = -63.201772, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1396900189, states[0] = -93.935120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407284030, states[0] = -93.919927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416951236, states[0] = -93.933169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426778100, states[0] = -93.937893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437524444, states[0] = -93.912280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447083896, states[0] = -93.927639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457385215, states[0] = -93.916374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466414375, states[0] = -93.838775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476550165, states[0] = -93.916847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486988934, states[0] = -93.931489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493771018, states[0] = -93.906244, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.777993
 - CaMKt in component CaMK (millimolar): 0.002071
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.710671
 - nass in component intracellular_ions (millimolar): 6.710795
 - ki in component intracellular_ions (millimolar): 145.148537
 - kss in component intracellular_ions (millimolar): 145.148527
 - cansr in component intracellular_ions (millimolar): 1.830652
 - cajsr in component intracellular_ions (millimolar): 1.830486
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004053
 - hf in component INa (dimensionless): 0.859091
 - hs in component INa (dimensionless): 0.859092
 - j in component INa (dimensionless): 0.859096
 - hsp in component INa (dimensionless): 0.687627
 - jp in component INa (dimensionless): 0.859098
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698575
 - hLp in component INaL (dimensionless): 0.502621
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.991402
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.996545
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996467
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005246
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008159
 - xs1 in component IKs (dimensionless): 0.041266
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:22:48 (24607): called boinc_finish(0)

</stderr_txt>
]]>


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