𝕏

Task 55650228

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446_1
Workunit 26425982
Created 1 Jul 2024, 15:53:46 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 5:07:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 50 min 53 sec
CPU time 1 hours 41 min 50 sec
Validate state Valid
Credit 41.94
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446_1_r792106388_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446_1_r792106388_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.409233
     * GNaL_b in INaL: 0.005670
     * Gto_b in Ito: 0.085786
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.168166
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.222490
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030538
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7436451, states[0] = -94.245262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17529884, states[0] = -94.200481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27802544, states[0] = -94.191011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38757196, states[0] = -94.182845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48939041, states[0] = -94.174213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59793373, states[0] = -94.179686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69730751, states[0] = -94.180902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80136162, states[0] = -26.298158, states[40]= 0.001894
Saving checkpoint... 
Iteration: 91030244, states[0] = 29.819592, states[40]= 0.000140
Saving checkpoint... 
Iteration: 101418564, states[0] = -94.106735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111735939, states[0] = -94.181904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121724995, states[0] = -94.182026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132910540, states[0] = -94.176664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143349940, states[0] = -94.025788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154031073, states[0] = 29.610710, states[40]= 0.000131
Saving checkpoint... 
Iteration: 165108465, states[0] = -3.335323, states[40]= 0.003164
Saving checkpoint... 
Iteration: 176046639, states[0] = 24.875772, states[40]= 0.000237
Saving checkpoint... 
Iteration: 186350659, states[0] = -94.026919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196641636, states[0] = -94.179601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206970479, states[0] = -94.173722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217144404, states[0] = -33.008107, states[40]= 0.001473
Saving checkpoint... 
Iteration: 227445276, states[0] = -94.126288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237862877, states[0] = -94.178520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248229195, states[0] = -93.638019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258563532, states[0] = -94.170016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268238360, states[0] = -93.685063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279311537, states[0] = -93.948126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289783492, states[0] = -94.180904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300285173, states[0] = -93.874117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310029839, states[0] = 29.907266, states[40]= 0.000145
Saving checkpoint... 
Iteration: 320739858, states[0] = -94.181429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331492055, states[0] = -94.149553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342190862, states[0] = -75.611964, states[40]= 0.000003
Saving checkpoint... 
Iteration: 352424671, states[0] = -94.111173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363476027, states[0] = -94.142460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373523259, states[0] = -94.159992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384309590, states[0] = -93.942804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391856618, states[0] = -94.178014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402528605, states[0] = -94.161350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412127979, states[0] = -19.634107, states[40]= 0.001496
Saving checkpoint... 
Iteration: 423086900, states[0] = 8.722168, states[40]= 0.002057
Saving checkpoint... 
Iteration: 433239793, states[0] = -93.691191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443786062, states[0] = -94.180074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454222807, states[0] = -93.595052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465024695, states[0] = 30.954951, states[40]= 0.000424
Saving checkpoint... 
Iteration: 475771738, states[0] = -94.180227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486511991, states[0] = -94.155968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496669413, states[0] = -94.179580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506879125, states[0] = -94.176507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517294631, states[0] = -93.901880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527734216, states[0] = -94.180422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538203520, states[0] = -91.052680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548833675, states[0] = -94.178097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559169304, states[0] = -53.945950, states[40]= 0.000110
Saving checkpoint... 
Iteration: 569188416, states[0] = -72.502159, states[40]= 0.000005
Saving checkpoint... 
Iteration: 575793528, states[0] = -94.179223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586733671, states[0] = -94.180128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597196183, states[0] = -83.114829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607966160, states[0] = -94.171959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618308001, states[0] = -93.937631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628730818, states[0] = -94.179926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639410780, states[0] = -94.098147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649675164, states[0] = -94.179021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660036272, states[0] = 28.203425, states[40]= 0.000132
Saving checkpoint... 
Iteration: 670853130, states[0] = -94.176753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681771286, states[0] = -94.179203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691915831, states[0] = -94.173939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702821294, states[0] = -94.177753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709551693, states[0] = -94.165400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718942653, states[0] = -94.172540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730073116, states[0] = 14.755728, states[40]= 0.001093
Saving checkpoint... 
Iteration: 737809422, states[0] = -94.177957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748796044, states[0] = -94.178288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759267946, states[0] = -93.811471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768819343, states[0] = -94.177487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779340525, states[0] = -94.006604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789798479, states[0] = -94.178016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800284632, states[0] = -93.869829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810477422, states[0] = -94.140864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821136286, states[0] = -26.466324, states[40]= 0.001891
Saving checkpoint... 
Iteration: 831734488, states[0] = -94.178897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842289449, states[0] = -93.884756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853278053, states[0] = -93.847633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864309958, states[0] = -93.941278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874535088, states[0] = -94.160695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884708432, states[0] = -94.178558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894779653, states[0] = -94.177961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905709879, states[0] = -94.178466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916314432, states[0] = -93.951843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926451965, states[0] = -94.126905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936982270, states[0] = -94.169517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947570910, states[0] = -94.167887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957800218, states[0] = -94.177125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968363908, states[0] = -94.043220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980087154, states[0] = 8.605228, states[40]= 0.002078
Saving checkpoint... 
Iteration: 990248460, states[0] = -93.728952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997329178, states[0] = -93.983765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007002447, states[0] = 41.863361, states[40]= 0.766194
Saving checkpoint... 
Iteration: 1017840135, states[0] = -94.175509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028975732, states[0] = -94.169377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039480551, states[0] = -94.141136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049333081, states[0] = -93.991266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058758280, states[0] = -94.177533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070356697, states[0] = -94.032054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079694336, states[0] = -94.177372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086952694, states[0] = -94.170210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097861146, states[0] = -94.174292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108266894, states[0] = -93.805655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118983704, states[0] = -94.168533, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446_1_r792106388_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_2000-conf_446_1_r792106388_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.409233
     * GNaL_b in INaL: 0.005670
     * Gto_b in Ito: 0.085786
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.168166
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.222490
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030538
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1118983704
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.168533 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1129060769, states[0] = 19.692366, states[40]= 0.000555
Saving checkpoint... 
Iteration: 1139369117, states[0] = -94.049582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149542152, states[0] = -94.161050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159745819, states[0] = -94.177176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170297514, states[0] = -93.906806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180537488, states[0] = -94.159764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191158371, states[0] = -44.542121, states[40]= 0.000417
Saving checkpoint... 
Iteration: 1198393992, states[0] = -94.079034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208320379, states[0] = -93.963998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218268040, states[0] = -93.809478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228370618, states[0] = -94.051145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238185797, states[0] = -69.456414, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1248267213, states[0] = -93.806164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258060052, states[0] = 19.968170, states[40]= 0.000532
Saving checkpoint... 
Iteration: 1267842959, states[0] = -94.174149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276977216, states[0] = -94.168060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287567858, states[0] = -94.165650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294448439, states[0] = -94.122921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304793467, states[0] = -94.175569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315544735, states[0] = -94.160820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323717405, states[0] = -94.176424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334806342, states[0] = -94.175056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345381054, states[0] = -94.063742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355880699, states[0] = -94.172180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366116246, states[0] = -9.419379, states[40]= 0.002395
Saving checkpoint... 
Iteration: 1376788338, states[0] = -94.175340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383504889, states[0] = -94.149068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394592709, states[0] = -94.168933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405268111, states[0] = -93.808790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415459214, states[0] = -94.128606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425925452, states[0] = -94.169808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436807742, states[0] = -94.174503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447571932, states[0] = -94.165553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458403138, states[0] = -94.086938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468094311, states[0] = 5.108309, states[40]= 0.002663
Saving checkpoint... 
Iteration: 1478539547, states[0] = -94.158775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489478497, states[0] = -94.137947, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.041753
 - CaMKt in component CaMK (millimolar): 0.005778
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.826197
 - nass in component intracellular_ions (millimolar): 6.826315
 - ki in component intracellular_ions (millimolar): 145.009043
 - kss in component intracellular_ions (millimolar): 145.009029
 - cansr in component intracellular_ions (millimolar): 1.851827
 - cajsr in component intracellular_ions (millimolar): 1.850940
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003947
 - hf in component INa (dimensionless): 0.864257
 - hs in component INa (dimensionless): 0.864259
 - j in component INa (dimensionless): 0.864270
 - hsp in component INa (dimensionless): 0.696868
 - jp in component INa (dimensionless): 0.864277
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.705785
 - hLp in component INaL (dimensionless): 0.493720
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999848
 - iS in component Ito (dimensionless): 0.886718
 - ap in component Ito (dimensionless): 0.000337
 - iFp in component Ito (dimensionless): 0.999848
 - iSp in component Ito (dimensionless): 0.926352
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.971417
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004606
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.109838
 - xs1 in component IKs (dimensionless): 0.135467
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997554
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:39:44 (41429): called boinc_finish(0)

</stderr_txt>
]]>


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