𝕏

Task 55650200

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_1000-conf_946_1
Workunit 26425968
Created 1 Jul 2024, 15:53:46 UTC
Sent 2 Jul 2024, 7:37:18 UTC
Report deadline 5 Jul 2024, 7:37:18 UTC
Received 4 Jul 2024, 6:37:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236159
Run time 1 hours 51 min 32 sec
CPU time 1 hours 41 min 54 sec
Validate state Valid
Credit 44.40
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_1000-conf_946.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_1000-conf_946_1_r287021816_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_1000-conf_946_1_r287021816_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.714219
     * GNaL_b in INaL: 0.006214
     * Gto_b in Ito: 0.082436
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031775
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.161550
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.950884
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032937
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10393928, states[0] = -94.360385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20904600, states[0] = -94.329389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30943614, states[0] = -94.348572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41192219, states[0] = -92.744867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51760061, states[0] = -94.075604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61790280, states[0] = -94.172452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71713223, states[0] = -93.862455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79079146, states[0] = 9.184306, states[40]= 0.001989
Saving checkpoint... 
Iteration: 89743157, states[0] = -94.018659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99606079, states[0] = -8.595223, states[40]= 0.002642
Saving checkpoint... 
Iteration: 109700124, states[0] = -93.717684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119211598, states[0] = -93.858646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128926261, states[0] = -94.362252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138562014, states[0] = 17.031225, states[40]= 0.000780
Saving checkpoint... 
Iteration: 147847859, states[0] = -94.291755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156746725, states[0] = -94.037726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166788054, states[0] = -94.177073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173628804, states[0] = -29.954141, states[40]= 0.001531
Saving checkpoint... 
Iteration: 184088802, states[0] = 3.919645, states[40]= 0.002842
Saving checkpoint... 
Iteration: 194148808, states[0] = -48.291796, states[40]= 0.000237
Saving checkpoint... 
Iteration: 202998856, states[0] = -94.390949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213085774, states[0] = 5.616147, states[40]= 0.002572
Saving checkpoint... 
Iteration: 223160079, states[0] = -59.172408, states[40]= 0.000048
Saving checkpoint... 
Iteration: 233591605, states[0] = 2.248104, states[40]= 0.003059
Saving checkpoint... 
Iteration: 244107556, states[0] = -10.102285, states[40]= 0.002382
Saving checkpoint... 
Iteration: 253944293, states[0] = -94.371712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260875519, states[0] = -94.323559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271589956, states[0] = 3.240900, states[40]= 0.002936
Saving checkpoint... 
Iteration: 281300820, states[0] = -94.207725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291728447, states[0] = -93.952441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302231852, states[0] = -93.969251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312001663, states[0] = 48.355385, states[40]= 0.707527
Saving checkpoint... 
Iteration: 322353921, states[0] = -94.298686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332583954, states[0] = 6.594824, states[40]= 0.002402
Saving checkpoint... 
Iteration: 343129013, states[0] = -30.154429, states[40]= 0.001518
Saving checkpoint... 
Iteration: 353701013, states[0] = -93.742868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363939134, states[0] = -94.368152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375285394, states[0] = -94.168248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381662254, states[0] = -61.340276, states[40]= 0.000034
Saving checkpoint... 
Iteration: 392295121, states[0] = -94.193153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402702291, states[0] = -93.767110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413895269, states[0] = -94.339725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424425806, states[0] = -94.360440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433903502, states[0] = -94.345841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444469572, states[0] = -94.380053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455029168, states[0] = 29.996713, states[40]= 0.000166
Saving checkpoint... 
Iteration: 464969593, states[0] = -94.379854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475422561, states[0] = -94.358031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485570362, states[0] = 13.265081, states[40]= 0.001260
Saving checkpoint... 
Iteration: 496210416, states[0] = -93.848916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506808569, states[0] = -94.222395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516080839, states[0] = 8.213498, states[40]= 0.002113
Saving checkpoint... 
Iteration: 526102506, states[0] = -5.572352, states[40]= 0.003053
Saving checkpoint... 
Iteration: 535876059, states[0] = -94.321336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546167021, states[0] = -66.319654, states[40]= 0.000015
Saving checkpoint... 
Iteration: 556754070, states[0] = -94.063910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566495808, states[0] = -94.386666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576556139, states[0] = 19.563042, states[40]= 0.000540
Saving checkpoint... 
Iteration: 586946831, states[0] = -94.369547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593140341, states[0] = -40.364921, states[40]= 0.000640
Saving checkpoint... 
Iteration: 602993113, states[0] = -94.385603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613512496, states[0] = 32.573717, states[40]= 0.025599
Saving checkpoint... 
Iteration: 624161603, states[0] = -60.682360, states[40]= 0.000038
Saving checkpoint... 
Iteration: 634767010, states[0] = -94.109886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645463109, states[0] = -94.375688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655763209, states[0] = -94.096628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666249224, states[0] = -94.043468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676734512, states[0] = -93.978240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686441378, states[0] = -94.365996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696799674, states[0] = -94.200872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707386481, states[0] = -94.329357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717231939, states[0] = -93.965406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727452530, states[0] = -94.370631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737003002, states[0] = 40.659340, states[40]= 0.671654
Saving checkpoint... 
Iteration: 747960228, states[0] = -94.373553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758355528, states[0] = -94.296286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768753808, states[0] = -94.060717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779015241, states[0] = 32.708033, states[40]= 0.009866
Saving checkpoint... 
Iteration: 789516329, states[0] = 32.677042, states[40]= 0.006769
Saving checkpoint... 
Iteration: 799373698, states[0] = -94.316304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809823326, states[0] = -94.247776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819511658, states[0] = 32.473740, states[40]= 0.034261
Saving checkpoint... 
Iteration: 830241839, states[0] = -94.010334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840654839, states[0] = -54.071516, states[40]= 0.000104
Saving checkpoint... 
Iteration: 850784001, states[0] = -94.159574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860934263, states[0] = -94.360666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871619933, states[0] = -21.943619, states[40]= 0.001477
Saving checkpoint... 
Iteration: 882537610, states[0] = 27.067669, states[40]= 0.000161
Saving checkpoint... 
Iteration: 893485254, states[0] = -94.380513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903383534, states[0] = -94.324729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913984315, states[0] = -94.380034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924408919, states[0] = -94.344745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934376670, states[0] = -94.317910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944525348, states[0] = 31.108515, states[40]= 0.000361
Saving checkpoint... 
Iteration: 952101983, states[0] = -5.131479, states[40]= 0.003102
Saving checkpoint... 
Iteration: 963014396, states[0] = 32.700527, states[40]= 0.013226
Saving checkpoint... 
Iteration: 973333948, states[0] = -94.263879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984126851, states[0] = -28.212780, states[40]= 0.001606
Saving checkpoint... 
Iteration: 994601354, states[0] = -4.614634, states[40]= 0.003152
Saving checkpoint... 
Iteration: 1005025456, states[0] = 31.079917, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1014775256, states[0] = -94.132443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024374562, states[0] = -94.314903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034879777, states[0] = -94.319900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045427151, states[0] = -94.354940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055674838, states[0] = -75.880425, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1066198552, states[0] = -93.663030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076480934, states[0] = -94.377388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086477137, states[0] = -94.376105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093764237, states[0] = -94.095729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104307758, states[0] = -94.214615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115090798, states[0] = 2.743438, states[40]= 0.003001
Saving checkpoint... 
Iteration: 1121886458, states[0] = -94.325148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132831859, states[0] = -94.258932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143501115, states[0] = 48.880523, states[40]= 0.389252
Saving checkpoint... 
Iteration: 1154473897, states[0] = -94.374367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164639507, states[0] = -39.593937, states[40]= 0.000698
Saving checkpoint... 
Iteration: 1175267485, states[0] = -94.105950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186361195, states[0] = -94.298770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197013961, states[0] = 32.685649, states[40]= 0.015381
Saving checkpoint... 
Iteration: 1208224668, states[0] = -93.923582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219181894, states[0] = -85.995195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230396296, states[0] = -94.332297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240015481, states[0] = 32.706527, states[40]= 0.009077
Saving checkpoint... 
Iteration: 1251076357, states[0] = 10.439278, states[40]= 0.001719
Saving checkpoint... 
Iteration: 1261945877, states[0] = -94.362306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271871451, states[0] = -94.309214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283022125, states[0] = 31.881384, states[40]= 0.000952
Saving checkpoint... 
Iteration: 1293715814, states[0] = -93.874200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304567646, states[0] = 14.510416, states[40]= 0.001084
Saving checkpoint... 
Iteration: 1314645637, states[0] = -45.280830, states[40]= 0.000353
Saving checkpoint... 
Iteration: 1325606455, states[0] = -9.063392, states[40]= 0.002552
Saving checkpoint... 
Iteration: 1335971639, states[0] = -94.371780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346327420, states[0] = -94.249429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357365260, states[0] = -94.301675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367959332, states[0] = -94.366953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379053474, states[0] = 20.696504, states[40]= 0.000455
Saving checkpoint... 
Iteration: 1386524922, states[0] = 31.221785, states[40]= 0.000406
Saving checkpoint... 
Iteration: 1397867392, states[0] = -94.303615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409363666, states[0] = -94.299356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420383936, states[0] = -94.319871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431006861, states[0] = 32.180073, states[40]= 0.181431
Saving checkpoint... 
Iteration: 1442067710, states[0] = 14.481957, states[40]= 0.001088
Saving checkpoint... 
Iteration: 1453314885, states[0] = -94.225540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463520731, states[0] = 32.154252, states[40]= 0.001506
Saving checkpoint... 
Iteration: 1471162979, states[0] = -62.052525, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1478103891, states[0] = -6.751566, states[40]= 0.002905
Saving checkpoint... 
Iteration: 1485658269, states[0] = -57.380970, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1493812628, states[0] = -94.220670, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.254172
 - CaMKt in component CaMK (millimolar): 0.017765
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.016822
 - nass in component intracellular_ions (millimolar): 7.016945
 - ki in component intracellular_ions (millimolar): 144.762855
 - kss in component intracellular_ions (millimolar): 144.762836
 - cansr in component intracellular_ions (millimolar): 1.940637
 - cajsr in component intracellular_ions (millimolar): 1.896133
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003863
 - hf in component INa (dimensionless): 0.868301
 - hs in component INa (dimensionless): 0.868290
 - j in component INa (dimensionless): 0.868221
 - hsp in component INa (dimensionless): 0.704119
 - jp in component INa (dimensionless): 0.868172
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.685863
 - hLp in component INaL (dimensionless): 0.415291
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.594264
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.660125
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.898917
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999749
 - jca in component ICaL (dimensionless): 0.999964
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004584
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.400619
 - xs1 in component IKs (dimensionless): 0.293608
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997503
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:34:46 (41460): called boinc_finish(0)

</stderr_txt>
]]>


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