𝕏

Task 55645877

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942_0
Workunit 26423808
Created 1 Jul 2024, 15:51:50 UTC
Sent 2 Jul 2024, 7:07:37 UTC
Report deadline 5 Jul 2024, 10:00:25 UTC
Received 3 Jul 2024, 11:35:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 37 min 31 sec
CPU time 2 hours 34 min 31 sec
Validate state Valid
Credit 48.84
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 4.08 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942_0_r1776719010_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942_0_r1776719010_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 104.774747
     * GNaL_b in INaL: 0.005874
     * Gto_b in Ito: 0.083111
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031915
     * GKs_b in IKs: 0.000095
     * GK1_b in IK1: 0.163871
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.303649
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036659
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11136431, states[0] = -46.622229, states[40]= 0.000119
Saving checkpoint... 
Iteration: 22312182, states[0] = -94.803759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33454454, states[0] = -94.887559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44584650, states[0] = 2.287487, states[40]= 0.004833
Saving checkpoint... 
Iteration: 55720351, states[0] = -94.560966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66806476, states[0] = -94.766679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77944144, states[0] = -94.871603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89064391, states[0] = 12.580857, states[40]= 0.004104
Saving checkpoint... 
Iteration: 100241880, states[0] = -94.626863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111381326, states[0] = -94.838648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122514005, states[0] = 28.068145, states[40]= 0.013424
Saving checkpoint... 
Iteration: 133648009, states[0] = -54.796759, states[40]= 0.000048
Saving checkpoint... 
Iteration: 144792990, states[0] = -94.741243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155889569, states[0] = -94.842908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167043784, states[0] = 20.586626, states[40]= 0.002518
Saving checkpoint... 
Iteration: 178216244, states[0] = -94.538792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189355144, states[0] = -94.817326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200497771, states[0] = -94.882540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211681547, states[0] = -93.761056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222781468, states[0] = -94.719830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233969176, states[0] = -94.875689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245090894, states[0] = -1.489147, states[40]= 0.004517
Saving checkpoint... 
Iteration: 256221891, states[0] = -94.559212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267361676, states[0] = -94.822433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278495826, states[0] = -94.881779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289607629, states[0] = -15.745990, states[40]= 0.001695
Saving checkpoint... 
Iteration: 300762778, states[0] = -94.679746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311887129, states[0] = -94.840500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323035507, states[0] = 23.426489, states[40]= 0.002011
Saving checkpoint... 
Iteration: 334166768, states[0] = -78.338806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 345332665, states[0] = -94.794537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356460025, states[0] = -94.872598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367572812, states[0] = 8.811929, states[40]= 0.004626
Saving checkpoint... 
Iteration: 378666597, states[0] = -78.060889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389820891, states[0] = -94.780538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400986326, states[0] = -94.879271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412136349, states[0] = -42.722459, states[40]= 0.000284
Saving checkpoint... 
Iteration: 423293416, states[0] = -94.740474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434431091, states[0] = -94.862266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445585426, states[0] = 2.054807, states[40]= 0.004843
Saving checkpoint... 
Iteration: 456760539, states[0] = -94.673813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467479617, states[0] = -94.877451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478617691, states[0] = -25.134745, states[40]= 0.001324
Saving checkpoint... 
Iteration: 489779181, states[0] = -94.714335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500935907, states[0] = -94.863898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512103383, states[0] = -11.756368, states[40]= 0.002348
Saving checkpoint... 
Iteration: 523296351, states[0] = -94.744948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534494317, states[0] = -94.880494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545667381, states[0] = -79.338026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556836227, states[0] = -94.797589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567629571, states[0] = -36.162162, states[40]= 0.000641
Saving checkpoint... 
Iteration: 578771563, states[0] = -94.698387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589975277, states[0] = -94.875912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601163079, states[0] = -72.673361, states[40]= 0.000003
Saving checkpoint... 
Iteration: 612333284, states[0] = -94.794204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623534568, states[0] = 23.731280, states[40]= 0.001965
Saving checkpoint... 
Iteration: 634704089, states[0] = -94.488264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645853238, states[0] = -94.813804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656998635, states[0] = -94.880905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668209272, states[0] = -94.509577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679370366, states[0] = -94.827634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690570929, states[0] = 9.703266, states[40]= 0.004528
Saving checkpoint... 
Iteration: 701763145, states[0] = -94.679075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712960389, states[0] = -94.871358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724125424, states[0] = -32.271801, states[40]= 0.000941
Saving checkpoint... 
Iteration: 735318730, states[0] = -94.776495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746530080, states[0] = 25.112264, states[40]= 0.001789
Saving checkpoint... 
Iteration: 757718190, states[0] = -94.543716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768867707, states[0] = -94.825287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780075306, states[0] = 7.592597, states[40]= 0.004735
Saving checkpoint... 
Iteration: 791258397, states[0] = -94.667309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802453034, states[0] = -94.868754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813662597, states[0] = -71.984089, states[40]= 0.000003
Saving checkpoint... 
Iteration: 824851090, states[0] = -94.811194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836026154, states[0] = 26.185834, states[40]= 0.001774
Saving checkpoint... 
Iteration: 847210313, states[0] = -94.513052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858423778, states[0] = -94.857619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869617053, states[0] = -24.546182, states[40]= 0.001331
Saving checkpoint... 
Iteration: 880800830, states[0] = -94.750706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892027146, states[0] = 25.929278, states[40]= 0.001756
Saving checkpoint... 
Iteration: 903211915, states[0] = -94.519167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914401984, states[0] = -94.846867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925597362, states[0] = -6.422998, states[40]= 0.003566
Saving checkpoint... 
Iteration: 936793080, states[0] = -94.737957, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942_0_r1776719010_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-CLVPET_Block_Ks_95-conf_942_0_r1776719010_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 104.774747
     * GNaL_b in INaL: 0.005874
     * Gto_b in Ito: 0.083111
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031915
     * GKs_b in IKs: 0.000095
     * GK1_b in IK1: 0.163871
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.303649
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036659
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 936793080
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.737957 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 947954024, states[0] = -94.868519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959153551, states[0] = -60.775772, states[40]= 0.000018
Saving checkpoint... 
Iteration: 970328016, states[0] = -94.786910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981499822, states[0] = -94.879913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992629510, states[0] = -36.102696, states[40]= 0.000646
Saving checkpoint... 
Iteration: 1003815571, states[0] = -94.771368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014950570, states[0] = -94.867152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026099040, states[0] = -7.847758, states[40]= 0.003231
Saving checkpoint... 
Iteration: 1037287734, states[0] = -94.728288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048434583, states[0] = -94.861321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059584315, states[0] = 2.719931, states[40]= 0.004867
Saving checkpoint... 
Iteration: 1070728763, states[0] = -94.580063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081909077, states[0] = -94.849924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093092293, states[0] = -2.479057, states[40]= 0.004367
Saving checkpoint... 
Iteration: 1104278891, states[0] = -94.711426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115445742, states[0] = -94.865147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126587626, states[0] = 0.689826, states[40]= 0.004757
Saving checkpoint... 
Iteration: 1137768410, states[0] = -94.689404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148947250, states[0] = -94.865537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160110148, states[0] = -18.121822, states[40]= 0.001473
Saving checkpoint... 
Iteration: 1171336730, states[0] = -94.795793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182511989, states[0] = 28.116725, states[40]= 0.025396
Saving checkpoint... 
Iteration: 1193705123, states[0] = -94.490514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204839657, states[0] = -94.798712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215994823, states[0] = -94.878026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227146518, states[0] = -53.164981, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1238329080, states[0] = -94.787120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249535640, states[0] = 23.384163, states[40]= 0.002019
Saving checkpoint... 
Iteration: 1260694867, states[0] = -94.437114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271897772, states[0] = -94.843194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283072660, states[0] = 8.886239, states[40]= 0.004619
Saving checkpoint... 
Iteration: 1294223926, states[0] = -94.562484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305372819, states[0] = -94.827069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316580667, states[0] = 4.793378, states[40]= 0.004875
Saving checkpoint... 
Iteration: 1327701418, states[0] = -94.473777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338816161, states[0] = -94.770875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349962578, states[0] = -94.869595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361098123, states[0] = -7.061035, states[40]= 0.003417
Saving checkpoint... 
Iteration: 1372249937, states[0] = -94.643202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383382512, states[0] = -94.833478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394518223, states[0] = 27.739659, states[40]= 0.004232
Saving checkpoint... 
Iteration: 1405658425, states[0] = -66.479971, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1416798658, states[0] = -94.745262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427963771, states[0] = -94.869644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439127090, states[0] = -33.823825, states[40]= 0.000818
Saving checkpoint... 
Iteration: 1450303105, states[0] = -94.752027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461443658, states[0] = -94.863113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472611462, states[0] = -19.355822, states[40]= 0.001407
Saving checkpoint... 
Iteration: 1483815982, states[0] = -94.770089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494992436, states[0] = -94.876475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506119513, states[0] = -95.210740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517145269, states[0] = 18.948190, states[40]= 0.001632
Saving checkpoint... 
Iteration: 1528166026, states[0] = -94.867769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539137775, states[0] = -94.767226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550128878, states[0] = -94.681652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561090217, states[0] = 2.825634, states[40]= 0.004540
Saving checkpoint... 
Iteration: 1572018459, states[0] = 26.879143, states[40]= 0.003923
Saving checkpoint... 
Iteration: 1582960347, states[0] = -94.559140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593871780, states[0] = -94.455861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604780584, states[0] = -94.547445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615679837, states[0] = -94.532625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626548077, states[0] = -94.458778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637395275, states[0] = -94.443415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648267858, states[0] = -94.456411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659128624, states[0] = -94.438809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669954936, states[0] = -94.428633, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.301825
 - CaMKt in component CaMK (millimolar): 0.001126
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.373704
 - nass in component intracellular_ions (millimolar): 6.373790
 - ki in component intracellular_ions (millimolar): 145.524521
 - kss in component intracellular_ions (millimolar): 145.524509
 - cansr in component intracellular_ions (millimolar): 1.565481
 - cajsr in component intracellular_ions (millimolar): 1.565505
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003844
 - hf in component INa (dimensionless): 0.869192
 - hs in component INa (dimensionless): 0.869192
 - j in component INa (dimensionless): 0.869193
 - hsp in component INa (dimensionless): 0.705807
 - jp in component INa (dimensionless): 0.869194
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.713063
 - hLp in component INaL (dimensionless): 0.520497
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997733
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999246
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998844
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002992
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001819
 - xs1 in component IKs (dimensionless): 0.023135
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997490
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:34:38 (84654): called boinc_finish(0)

</stderr_txt>
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