𝕏

Task 55642183

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_38_1
Workunit 26421962
Created 1 Jul 2024, 15:50:15 UTC
Sent 2 Jul 2024, 6:45:02 UTC
Report deadline 5 Jul 2024, 6:45:02 UTC
Received 2 Jul 2024, 9:55:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224487
Run time 2 hours 38 min 11 sec
CPU time 1 hours 35 min 15 sec
Validate state Valid
Credit 43.89
Device peak FLOPS 3.08 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.75 MB
Peak swap size 5.26 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_38.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_38_1_r1223842085_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_38_1_r1223842085_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.087014
     * GNaL_b in INaL: 0.005527
     * Gto_b in Ito: 0.081453
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031410
     * GKs_b in IKs: 0.001951
     * GK1_b in IK1: 0.161776
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.859770
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037631
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12025644, states[0] = 18.153450, states[40]= 0.008045
Saving checkpoint... 
Iteration: 19380334, states[0] = -86.735846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28441043, states[0] = -87.402695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37182916, states[0] = -87.374633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47657933, states[0] = -87.301792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58412744, states[0] = -87.310007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68820647, states[0] = -12.995687, states[40]= 0.002098
Saving checkpoint... 
Iteration: 78792425, states[0] = 10.118966, states[40]= 0.006031
Saving checkpoint... 
Iteration: 89133068, states[0] = -86.800443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99416091, states[0] = -87.309976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109627217, states[0] = -85.008250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120165199, states[0] = -87.306010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130290211, states[0] = 11.447840, states[40]= 0.006155
Saving checkpoint... 
Iteration: 140524796, states[0] = 19.151189, states[40]= 0.008107
Saving checkpoint... 
Iteration: 150636097, states[0] = -87.040664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161041523, states[0] = 10.710304, states[40]= 0.006080
Saving checkpoint... 
Iteration: 171669380, states[0] = -87.315816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182078474, states[0] = -22.246301, states[40]= 0.000878
Saving checkpoint... 
Iteration: 192317899, states[0] = -9.518204, states[40]= 0.002871
Saving checkpoint... 
Iteration: 202477738, states[0] = -87.428915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212318133, states[0] = -9.778977, states[40]= 0.002808
Saving checkpoint... 
Iteration: 221888166, states[0] = -87.127184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231569136, states[0] = -10.922504, states[40]= 0.002541
Saving checkpoint... 
Iteration: 241004623, states[0] = 28.880114, states[40]= 0.124543
Saving checkpoint... 
Iteration: 251577896, states[0] = -21.529880, states[40]= 0.000934
Saving checkpoint... 
Iteration: 261154813, states[0] = -87.274369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270444212, states[0] = -87.372609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280797607, states[0] = 7.079320, states[40]= 0.005763
Saving checkpoint... 
Iteration: 290558927, states[0] = -0.864978, states[40]= 0.004826
Saving checkpoint... 
Iteration: 300798659, states[0] = 6.417383, states[40]= 0.005706
Saving checkpoint... 
Iteration: 311038995, states[0] = 12.140530, states[40]= 0.006229
Saving checkpoint... 
Iteration: 321243133, states[0] = -87.448152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331462973, states[0] = -87.406568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341765444, states[0] = 22.449740, states[40]= 0.017105
Saving checkpoint... 
Iteration: 351994580, states[0] = -87.449782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362417564, states[0] = -87.310592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372813156, states[0] = -4.585268, states[40]= 0.004069
Saving checkpoint... 
Iteration: 383375039, states[0] = -83.334285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392352346, states[0] = -51.507762, states[40]= 0.000022
Saving checkpoint... 
Iteration: 402365747, states[0] = -70.217787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 412549729, states[0] = 5.732320, states[40]= 0.005646
Saving checkpoint... 
Iteration: 422843807, states[0] = -40.859513, states[40]= 0.000112
Saving checkpoint... 
Iteration: 433307297, states[0] = 0.426248, states[40]= 0.005036
Saving checkpoint... 
Iteration: 444053913, states[0] = 2.915920, states[40]= 0.005364
Saving checkpoint... 
Iteration: 454599647, states[0] = -48.085979, states[40]= 0.000038
Saving checkpoint... 
Iteration: 465078198, states[0] = -21.899591, states[40]= 0.000905
Saving checkpoint... 
Iteration: 475570399, states[0] = -12.397274, states[40]= 0.002218
Saving checkpoint... 
Iteration: 486030387, states[0] = 16.625347, states[40]= 0.007002
Saving checkpoint... 
Iteration: 496738665, states[0] = -87.442691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507346035, states[0] = -43.590423, states[40]= 0.000075
Saving checkpoint... 
Iteration: 517971468, states[0] = -87.419581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528352307, states[0] = -51.457651, states[40]= 0.000023
Saving checkpoint... 
Iteration: 538924330, states[0] = -87.327786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549353304, states[0] = -52.736779, states[40]= 0.000018
Saving checkpoint... 
Iteration: 559601921, states[0] = -50.964759, states[40]= 0.000024
Saving checkpoint... 
Iteration: 570163497, states[0] = -87.299400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580792257, states[0] = 10.292456, states[40]= 0.006040
Saving checkpoint... 
Iteration: 591651494, states[0] = -87.263024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602311958, states[0] = -3.470108, states[40]= 0.004318
Saving checkpoint... 
Iteration: 612946772, states[0] = -87.377357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623800600, states[0] = 5.165159, states[40]= 0.005595
Saving checkpoint... 
Iteration: 634548456, states[0] = 6.546221, states[40]= 0.005717
Saving checkpoint... 
Iteration: 644900599, states[0] = -87.259714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655546617, states[0] = 7.692778, states[40]= 0.005814
Saving checkpoint... 
Iteration: 665956918, states[0] = -87.396053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676624210, states[0] = -82.525912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687306949, states[0] = 0.693512, states[40]= 0.005075
Saving checkpoint... 
Iteration: 698067034, states[0] = -8.555669, states[40]= 0.003105
Saving checkpoint... 
Iteration: 708604714, states[0] = -54.562706, states[40]= 0.000014
Saving checkpoint... 
Iteration: 719233034, states[0] = -87.435417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730081413, states[0] = -25.834579, states[40]= 0.000648
Saving checkpoint... 
Iteration: 740748114, states[0] = -87.453365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751266684, states[0] = 22.089732, states[40]= 0.014497
Saving checkpoint... 
Iteration: 761987210, states[0] = -87.440664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772668758, states[0] = -87.313358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783320920, states[0] = -13.015325, states[40]= 0.002091
Saving checkpoint... 
Iteration: 793681206, states[0] = -87.344030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804111825, states[0] = -64.278199, states[40]= 0.000003
Saving checkpoint... 
Iteration: 814566798, states[0] = -8.298523, states[40]= 0.003168
Saving checkpoint... 
Iteration: 824796019, states[0] = 8.058879, states[40]= 0.005845
Saving checkpoint... 
Iteration: 835263425, states[0] = 22.998475, states[40]= 0.023649
Saving checkpoint... 
Iteration: 845801790, states[0] = 4.375138, states[40]= 0.005519
Saving checkpoint... 
Iteration: 856438087, states[0] = -87.359321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866681006, states[0] = -87.343499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877329263, states[0] = -23.205141, states[40]= 0.000810
Saving checkpoint... 
Iteration: 887828694, states[0] = -22.507601, states[40]= 0.000859
Saving checkpoint... 
Iteration: 898398066, states[0] = -87.249060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908802666, states[0] = 3.781341, states[40]= 0.005459
Saving checkpoint... 
Iteration: 919698973, states[0] = -87.381324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930332921, states[0] = -27.672075, states[40]= 0.000550
Saving checkpoint... 
Iteration: 940145019, states[0] = -87.232071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949716761, states[0] = -87.412035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959013670, states[0] = 22.933556, states[40]= 0.022658
Saving checkpoint... 
Iteration: 969529202, states[0] = 17.191052, states[40]= 0.007170
Saving checkpoint... 
Iteration: 979837084, states[0] = -32.719508, states[40]= 0.000326
Saving checkpoint... 
Iteration: 990186560, states[0] = -87.355888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000791585, states[0] = 10.679890, states[40]= 0.006077
Saving checkpoint... 
Iteration: 1010603463, states[0] = -52.940833, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1020954009, states[0] = -87.390568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031427543, states[0] = -87.335175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042240934, states[0] = -87.444914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052698755, states[0] = -87.380785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063548485, states[0] = 6.528093, states[40]= 0.005716
Saving checkpoint... 
Iteration: 1074284689, states[0] = 14.460298, states[40]= 0.006544
Saving checkpoint... 
Iteration: 1084660517, states[0] = -87.290567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095462185, states[0] = -87.404574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106045259, states[0] = 8.519652, states[40]= 0.005884
Saving checkpoint... 
Iteration: 1116707075, states[0] = -87.395911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127336268, states[0] = -31.732513, states[40]= 0.000365
Saving checkpoint... 
Iteration: 1137645681, states[0] = -87.236202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148621487, states[0] = -79.150993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159064952, states[0] = -6.354935, states[40]= 0.003648
Saving checkpoint... 
Iteration: 1169583029, states[0] = -27.803176, states[40]= 0.000544
Saving checkpoint... 
Iteration: 1180329893, states[0] = -23.976263, states[40]= 0.000759
Saving checkpoint... 
Iteration: 1190838837, states[0] = -34.836837, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1201313945, states[0] = -5.347464, states[40]= 0.003891
Saving checkpoint... 
Iteration: 1211776014, states[0] = 18.637210, states[40]= 0.007782
Saving checkpoint... 
Iteration: 1222270513, states[0] = 20.829912, states[40]= 0.010090
Saving checkpoint... 
Iteration: 1232775596, states[0] = 18.818035, states[40]= 0.007886
Saving checkpoint... 
Iteration: 1242282177, states[0] = 15.745184, states[40]= 0.006787
Saving checkpoint... 
Iteration: 1252508645, states[0] = 24.504239, states[40]= 0.062265
Saving checkpoint... 
Iteration: 1261204317, states[0] = -87.390901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271456144, states[0] = -87.394139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282121822, states[0] = -79.618014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292506613, states[0] = 25.868158, states[40]= 0.094223
Saving checkpoint... 
Iteration: 1302978119, states[0] = -87.428328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313087375, states[0] = -33.070758, states[40]= 0.000313
Saving checkpoint... 
Iteration: 1323329653, states[0] = -23.682274, states[40]= 0.000778
Saving checkpoint... 
Iteration: 1333762770, states[0] = 23.171651, states[40]= 0.026633
Saving checkpoint... 
Iteration: 1343974313, states[0] = -87.422959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354744675, states[0] = -87.448969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365213503, states[0] = -87.406475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375648247, states[0] = -87.249438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386182888, states[0] = -87.347338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396679212, states[0] = -87.338812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406859087, states[0] = -60.406273, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1417252931, states[0] = 34.620311, states[40]= 0.115331
Saving checkpoint... 
Iteration: 1426782196, states[0] = 15.735747, states[40]= 0.006785
Saving checkpoint... 
Iteration: 1437426903, states[0] = -87.333257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447647664, states[0] = -87.246664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458096468, states[0] = -44.123207, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1468594417, states[0] = -41.602950, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1479257147, states[0] = 25.406817, states[40]= 0.085029
Saving checkpoint... 
Iteration: 1490006447, states[0] = 26.032816, states[40]= 0.097132
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.330461
 - CaMKt in component CaMK (millimolar): 0.018646
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.701505
 - nass in component intracellular_ions (millimolar): 6.701603
 - ki in component intracellular_ions (millimolar): 145.260060
 - kss in component intracellular_ions (millimolar): 145.260034
 - cansr in component intracellular_ions (millimolar): 1.407957
 - cajsr in component intracellular_ions (millimolar): 1.194757
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007759
 - hf in component INa (dimensionless): 0.678827
 - hs in component INa (dimensionless): 0.678727
 - j in component INa (dimensionless): 0.678047
 - hsp in component INa (dimensionless): 0.432461
 - jp in component INa (dimensionless): 0.676127
 - mL in component INaL (dimensionless): 0.000209
 - hL in component INaL (dimensionless): 0.388163
 - hLp in component INaL (dimensionless): 0.182125
 - a in component Ito (dimensionless): 0.001039
 - iF in component Ito (dimensionless): 0.999509
 - iS in component Ito (dimensionless): 0.293826
 - ap in component Ito (dimensionless): 0.000529
 - iFp in component Ito (dimensionless): 0.999509
 - iSp in component Ito (dimensionless): 0.341523
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857508
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991006
 - jca in component ICaL (dimensionless): 0.991446
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004075
 - xrf in component IKr (dimensionless): 0.001736
 - xrs in component IKr (dimensionless): 0.677209
 - xs1 in component IKs (dimensionless): 0.382824
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996902
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:52:37 (14000): called boinc_finish(0)

</stderr_txt>
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