𝕏

Task 55642073

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_938_0
Workunit 26421908
Created 1 Jul 2024, 15:50:10 UTC
Sent 2 Jul 2024, 6:40:36 UTC
Report deadline 5 Jul 2024, 6:40:36 UTC
Received 2 Jul 2024, 15:21:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 51 min 14 sec
CPU time 1 hours 43 min 32 sec
Validate state Valid
Credit 45.77
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.75 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_938.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_938_0_r1307517048_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_938_0_r1307517048_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.299700
     * GNaL_b in INaL: 0.005535
     * Gto_b in Ito: 0.081270
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031330
     * GKs_b in IKs: 0.001965
     * GK1_b in IK1: 0.159853
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.020125
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034954
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12407811, states[0] = -22.134139, states[40]= 0.006703
Saving checkpoint... 
Iteration: 25910437, states[0] = -94.134377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39256425, states[0] = -94.160939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51472157, states[0] = -94.164467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64521418, states[0] = -94.131621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77520282, states[0] = -94.180502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89928337, states[0] = -94.177924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102510651, states[0] = -94.144889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115365653, states[0] = -94.197773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127911058, states[0] = -94.187854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140159648, states[0] = -9.033360, states[40]= 0.000643
Saving checkpoint... 
Iteration: 152817167, states[0] = -94.218580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165488532, states[0] = -94.199916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177478031, states[0] = -94.200689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189966613, states[0] = -94.191371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201043002, states[0] = -94.215452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213311237, states[0] = -94.206225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225843413, states[0] = -94.193582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238595511, states[0] = -94.196256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251181314, states[0] = -94.210608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263608862, states[0] = -94.198010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275951739, states[0] = -94.191705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288659186, states[0] = -94.210025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301256539, states[0] = -94.207606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313200948, states[0] = -94.209395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325214333, states[0] = -94.208803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336500176, states[0] = -94.148175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347265559, states[0] = -94.206816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358769302, states[0] = -94.218560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 369260240, states[0] = -94.206747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379795765, states[0] = -94.193083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389216310, states[0] = -94.208019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399672295, states[0] = -94.195223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410485716, states[0] = -94.135572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421360515, states[0] = -94.202932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 432219763, states[0] = -35.570518, states[40]= 0.003570
Saving checkpoint... 
Iteration: 443364624, states[0] = -94.202551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454746171, states[0] = -94.216514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465644934, states[0] = -94.195037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476568086, states[0] = -94.184370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487364157, states[0] = -94.202053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497739687, states[0] = -94.192741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509016187, states[0] = -94.213710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 518544374, states[0] = -94.173375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528999436, states[0] = -94.214032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539041266, states[0] = -94.212500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549884688, states[0] = -94.189632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560586750, states[0] = -94.190113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571417967, states[0] = -94.199486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582063833, states[0] = 28.193871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592002416, states[0] = 24.727377, states[40]= 1.426968
Saving checkpoint... 
Iteration: 602229530, states[0] = -41.642266, states[40]= 0.001820
Saving checkpoint... 
Iteration: 613495242, states[0] = -94.196879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625116893, states[0] = -94.208804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637227108, states[0] = -94.204758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648433875, states[0] = -94.073946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660192085, states[0] = -23.856476, states[40]= 0.005347
Saving checkpoint... 
Iteration: 671415219, states[0] = -94.198399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682805636, states[0] = -94.215571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693400145, states[0] = -94.198578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702972997, states[0] = -94.212841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713410529, states[0] = -94.198042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723363692, states[0] = -94.199315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734067571, states[0] = 27.011380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744246067, states[0] = -53.524500, states[40]= 0.000363
Saving checkpoint... 
Iteration: 753598157, states[0] = -94.192720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764315401, states[0] = -93.736987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775027922, states[0] = -94.210211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786022426, states[0] = 33.626535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796176170, states[0] = -18.348639, states[40]= 0.001672
Saving checkpoint... 
Iteration: 806840635, states[0] = -94.214252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 817522963, states[0] = -94.193785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828306892, states[0] = -93.693041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839613428, states[0] = -94.191369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850476956, states[0] = -94.122445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 861424760, states[0] = -94.195911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872073113, states[0] = 25.165977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883278569, states[0] = -94.200155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894373047, states[0] = -93.948935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905735581, states[0] = -94.188058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917008430, states[0] = -94.209217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927224951, states[0] = -94.201454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937610384, states[0] = -94.190297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947849699, states[0] = -94.185547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958461903, states[0] = -94.105788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967995000, states[0] = -94.183170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977715856, states[0] = -94.187601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988943620, states[0] = -94.210361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 999211999, states[0] = -94.201063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010730193, states[0] = -94.209139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021904742, states[0] = -94.183818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033510079, states[0] = -94.191597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045022934, states[0] = -94.207237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1056960364, states[0] = -94.209096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1068404584, states[0] = -94.019584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079147025, states[0] = -94.202430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090657480, states[0] = -94.200508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102334032, states[0] = -93.816064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114435086, states[0] = -94.070207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125147222, states[0] = -94.201888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134901184, states[0] = -94.209675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144267144, states[0] = -73.111263, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1153327089, states[0] = -94.195437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162950422, states[0] = -94.208145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173187122, states[0] = -94.199907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184020107, states[0] = 33.246781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194759946, states[0] = -94.208503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203967602, states[0] = -94.180784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214421741, states[0] = -94.048564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225855072, states[0] = -94.182213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237303975, states[0] = -94.195196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248418770, states[0] = -94.043220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259386421, states[0] = -94.192382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270611595, states[0] = -94.189057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282979079, states[0] = -94.205898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294766884, states[0] = -94.207590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306180285, states[0] = -20.009161, states[40]= 0.002578
Saving checkpoint... 
Iteration: 1318312881, states[0] = -93.717863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330130933, states[0] = 3.763605, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1341058750, states[0] = -94.202542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352615569, states[0] = -94.189098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364102281, states[0] = 14.557914, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1375666277, states[0] = -94.183966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387412706, states[0] = -94.190123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399593804, states[0] = -94.185286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411212080, states[0] = -94.196260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422809818, states[0] = -94.206999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433378453, states[0] = -94.190593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445389393, states[0] = -94.190127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456473347, states[0] = -94.111852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467303398, states[0] = -94.192537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479171448, states[0] = -94.196898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490372164, states[0] = -93.939449, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.052864
 - CaMKt in component CaMK (millimolar): 0.002625
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.824768
 - nass in component intracellular_ions (millimolar): 7.824924
 - ki in component intracellular_ions (millimolar): 143.960606
 - kss in component intracellular_ions (millimolar): 143.960590
 - cansr in component intracellular_ions (millimolar): 1.838921
 - cajsr in component intracellular_ions (millimolar): 1.840669
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003942
 - hf in component INa (dimensionless): 0.864470
 - hs in component INa (dimensionless): 0.864471
 - j in component INa (dimensionless): 0.864474
 - hsp in component INa (dimensionless): 0.697244
 - jp in component INa (dimensionless): 0.864476
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706240
 - hLp in component INaL (dimensionless): 0.511427
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.989991
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.995880
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994721
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004542
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009281
 - xs1 in component IKs (dimensionless): 0.054427
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997551
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:23:43 (18622): called boinc_finish(0)

</stderr_txt>
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