𝕏

Task 55635789

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1
Workunit 26418772
Created 1 Jul 2024, 15:47:26 UTC
Sent 2 Jul 2024, 5:58:33 UTC
Report deadline 5 Jul 2024, 5:58:33 UTC
Received 3 Jul 2024, 16:11:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 197686
Run time 2 hours 21 min 7 sec
CPU time 4 min 31 sec
Validate state Valid
Credit 42.85
Device peak FLOPS 3.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.77 MB
Peak swap size 1.96 MB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1_r1055320164_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1_r1055320164_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.476982
     * GNaL_b in INaL: 0.005629
     * Gto_b in Ito: 0.082792
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031392
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.166870
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.303075
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029184
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11446861, states[0] = -86.776506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22951627, states[0] = -86.710101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34633058, states[0] = -86.660284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46464629, states[0] = -86.606937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58216890, states[0] = -86.371333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70005143, states[0] = 24.643111, states[40]= 0.146310
Saving checkpoint... 
Iteration: 81937241, states[0] = -86.566186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93801050, states[0] = -86.558427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105653129, states[0] = -86.553286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117565524, states[0] = -86.549400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129491850, states[0] = -86.546681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141406872, states[0] = -86.545110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153235210, states[0] = -86.545714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165059540, states[0] = -86.547327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176600525, states[0] = -86.545750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188172049, states[0] = -62.601363, states[40]= 0.000003
Saving checkpoint... 
Iteration: 199816814, states[0] = -86.534806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211401035, states[0] = -86.538672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222995399, states[0] = -86.545098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234600837, states[0] = -86.543230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246149114, states[0] = -40.963698, states[40]= 0.000114
Saving checkpoint... 
Iteration: 257697073, states[0] = -86.534305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269287620, states[0] = -86.539198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280870126, states[0] = -86.546230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292396505, states[0] = -86.501150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303932137, states[0] = -86.532127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315546852, states[0] = -86.535444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326921124, states[0] = -86.545296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338526175, states[0] = -86.535113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350102242, states[0] = -3.547698, states[40]= 0.003183
Saving checkpoint... 
Iteration: 361630984, states[0] = -86.534453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373274406, states[0] = -86.539036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384956496, states[0] = -86.544630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396814751, states[0] = -86.546502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408680101, states[0] = -86.545736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420475714, states[0] = -86.526194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432368115, states[0] = -86.486438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444159969, states[0] = -50.562298, states[40]= 0.000024
Saving checkpoint... 
Iteration: 456098393, states[0] = -1.371043, states[40]= 0.003506
Saving checkpoint... 
Iteration: 467968608, states[0] = -86.531695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479878484, states[0] = -86.532293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491755577, states[0] = -86.533240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503571376, states[0] = -86.535008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515460357, states[0] = -86.536314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527339195, states[0] = -86.537977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539166099, states[0] = -86.540795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550990226, states[0] = -86.543985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562871732, states[0] = -86.545867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574676863, states[0] = -86.545611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586588280, states[0] = -86.541427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598501332, states[0] = -86.531146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610349576, states[0] = -86.474690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622190164, states[0] = -83.277638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634036748, states[0] = 19.359722, states[40]= 0.004497
Saving checkpoint... 
Iteration: 645846374, states[0] = -86.532491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657746220, states[0] = -86.533286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669595502, states[0] = -86.534717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681440038, states[0] = -86.536543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693323019, states[0] = -86.538187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705205409, states[0] = -86.540081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717125841, states[0] = -86.541480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729007393, states[0] = -86.543642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740842345, states[0] = -86.546175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752678476, states[0] = -86.545617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764584495, states[0] = -86.541104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776445924, states[0] = -86.518645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788213103, states[0] = -86.302265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799717518, states[0] = -86.533509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811252238, states[0] = -86.539278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822797836, states[0] = -86.546505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834361776, states[0] = -86.482574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845906019, states[0] = -86.532029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857458173, states[0] = -86.536276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869062241, states[0] = -86.542613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880597137, states[0] = -86.542005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892228063, states[0] = -86.330075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903842489, states[0] = -86.532471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915461060, states[0] = -86.536228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927096562, states[0] = -86.541972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938661193, states[0] = -86.545096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950254361, states[0] = -86.371483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961846771, states[0] = -86.532429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973496465, states[0] = -86.535779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985205624, states[0] = -86.540024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996835036, states[0] = -86.546199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008524146, states[0] = -86.534631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020361954, states[0] = -86.482648, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1_r1055320164_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1_r1055320164_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.476982
     * GNaL_b in INaL: 0.005629
     * Gto_b in Ito: 0.082792
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031392
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.166870
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.303075
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029184
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1020361954
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.482648 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1031819859, states[0] = -86.532619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043500236, states[0] = -86.535720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055196894, states[0] = -86.540161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066785028, states[0] = -86.546510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078382198, states[0] = -86.493958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090258390, states[0] = -86.377564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102317749, states[0] = -86.449170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114313239, states[0] = -86.444922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126359334, states[0] = -86.481003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138466987, states[0] = -86.524062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150559003, states[0] = -86.538768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162633375, states[0] = -86.543989, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1_r1055320164_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_4000-conf_332_1_r1055320164_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.476982
     * GNaL_b in INaL: 0.005629
     * Gto_b in Ito: 0.082792
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031392
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.166870
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.303075
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029184
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1162633375
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.543989 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1174752418, states[0] = -86.546489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186768378, states[0] = -86.546512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198567935, states[0] = -86.539618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210420127, states[0] = -86.510259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222237238, states[0] = -86.344466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234060920, states[0] = 13.115600, states[40]= 0.004261
Saving checkpoint... 
Iteration: 1245874307, states[0] = -86.532175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257521652, states[0] = -86.535426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269244568, states[0] = -86.539317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280982204, states[0] = -86.543989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292779213, states[0] = -86.546481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304727972, states[0] = -86.546319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316659590, states[0] = -86.544973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328584709, states[0] = -86.541014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340466587, states[0] = -86.523929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352436868, states[0] = -86.515838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364400751, states[0] = -86.502591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376184883, states[0] = -78.208323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388008023, states[0] = 22.413026, states[40]= 0.074780
Saving checkpoint... 
Iteration: 1399824308, states[0] = -86.532515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411650858, states[0] = -86.534014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423480504, states[0] = -86.535889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435394324, states[0] = -86.537015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447250181, states[0] = -86.539191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459098025, states[0] = -86.541845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470952522, states[0] = -86.544467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482896520, states[0] = -86.545353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494807467, states[0] = -86.546325, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.407272
 - CaMKt in component CaMK (millimolar): 0.000894
 - cass in component intracellular_ions (millimolar): 0.000070
 - nai in component intracellular_ions (millimolar): 6.071248
 - nass in component intracellular_ions (millimolar): 6.071294
 - ki in component intracellular_ions (millimolar): 145.924030
 - kss in component intracellular_ions (millimolar): 145.924019
 - cansr in component intracellular_ions (millimolar): 1.252948
 - cajsr in component intracellular_ions (millimolar): 1.253079
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008514
 - hf in component INa (dimensionless): 0.644893
 - hs in component INa (dimensionless): 0.644894
 - j in component INa (dimensionless): 0.644896
 - hsp in component INa (dimensionless): 0.396024
 - jp in component INa (dimensionless): 0.644898
 - mL in component INaL (dimensionless): 0.000249
 - hL in component INaL (dimensionless): 0.464071
 - hLp in component INaL (dimensionless): 0.274233
 - a in component Ito (dimensionless): 0.001105
 - iF in component Ito (dimensionless): 0.999423
 - iS in component Ito (dimensionless): 0.985520
 - ap in component Ito (dimensionless): 0.000563
 - iFp in component Ito (dimensionless): 0.999423
 - iSp in component Ito (dimensionless): 0.991634
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997473
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001278
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020555
 - xs1 in component IKs (dimensionless): 0.037406
 - xs2 in component IKs (dimensionless): 0.000227
 - xk1 in component IK1 (dimensionless): 0.997124
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:57:25 (10500): called boinc_finish(0)

</stderr_txt>
]]>


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