𝕏

Task 55634092

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_531_0
Workunit 26417924
Created 1 Jul 2024, 15:46:44 UTC
Sent 2 Jul 2024, 5:43:54 UTC
Report deadline 5 Jul 2024, 5:43:54 UTC
Received 2 Jul 2024, 14:02:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237076
Run time 2 hours 1 min 43 sec
CPU time 2 hours 1 min 28 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.43 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.11 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_531.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_531_0_r1062419961_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_531_0_r1062419961_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 102.169852
     * GNaL_b in INaL: 0.006084
     * Gto_b in Ito: 0.081031
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031793
     * GKs_b in IKs: 0.001974
     * GK1_b in IK1: 0.160022
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.494114
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034521
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7954663, states[0] = -86.853238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16285568, states[0] = -86.587442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24435092, states[0] = -86.872397, states[40]= 0.000002
Saving checkpoint... 
Iteration: 32697419, states[0] = -68.647527, states[40]= 0.000006
Saving checkpoint... 
Iteration: 40928353, states[0] = -86.900726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 48660477, states[0] = -34.077881, states[40]= 0.000392
Saving checkpoint... 
Iteration: 56770226, states[0] = -86.596485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64893763, states[0] = -86.903634, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72873226, states[0] = -86.886268, states[40]= 0.000002
Saving checkpoint... 
Iteration: 80907156, states[0] = -86.930488, states[40]= 0.000002
Saving checkpoint... 
Iteration: 88961873, states[0] = -86.973040, states[40]= 0.000002
Saving checkpoint... 
Iteration: 97033743, states[0] = 31.168120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104976094, states[0] = -86.986038, states[40]= 0.000002
Saving checkpoint... 
Iteration: 113353870, states[0] = -86.876666, states[40]= 0.000002
Saving checkpoint... 
Iteration: 121421041, states[0] = -86.957429, states[40]= 0.000002
Saving checkpoint... 
Iteration: 129498761, states[0] = -86.999445, states[40]= 0.000002
Saving checkpoint... 
Iteration: 138459678, states[0] = -86.984235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 146678134, states[0] = -57.927984, states[40]= 0.000036
Saving checkpoint... 
Iteration: 154793445, states[0] = -86.732942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162746477, states[0] = -86.513452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171014551, states[0] = 30.525931, states[40]= -0.000000
Saving checkpoint... 
Iteration: 179047360, states[0] = 27.769696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187041779, states[0] = 29.305852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195101278, states[0] = 5.114129, states[40]= 0.000045
Saving checkpoint... 
Iteration: 203172884, states[0] = -52.445132, states[40]= 0.000073
Saving checkpoint... 
Iteration: 211097117, states[0] = 7.230140, states[40]= 0.000031
Saving checkpoint... 
Iteration: 218953052, states[0] = -86.980422, states[40]= 0.000002
Saving checkpoint... 
Iteration: 226899442, states[0] = -86.939627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 234911158, states[0] = -86.950270, states[40]= 0.000002
Saving checkpoint... 
Iteration: 243214858, states[0] = -86.270546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243514526, states[0] = 30.508480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251798658, states[0] = -86.747710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260055552, states[0] = 25.100729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268076624, states[0] = 16.780956, states[40]= 0.000003
Saving checkpoint... 
Iteration: 276346562, states[0] = -86.864509, states[40]= 0.000002
Saving checkpoint... 
Iteration: 284502215, states[0] = 23.747292, states[40]= 1.699485
Saving checkpoint... 
Iteration: 292517480, states[0] = 31.356961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300629997, states[0] = -14.617447, states[40]= 0.000167
Saving checkpoint... 
Iteration: 308681748, states[0] = -62.775713, states[40]= 0.000019
Saving checkpoint... 
Iteration: 316853252, states[0] = -86.874071, states[40]= 0.000002
Saving checkpoint... 
Iteration: 325054943, states[0] = 25.311788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333352215, states[0] = -86.871381, states[40]= 0.000002
Saving checkpoint... 
Iteration: 341456335, states[0] = -86.975776, states[40]= 0.000002
Saving checkpoint... 
Iteration: 349719534, states[0] = -86.309845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357970497, states[0] = -86.981798, states[40]= 0.000002
Saving checkpoint... 
Iteration: 366197537, states[0] = -83.983581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374303818, states[0] = -86.757165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382326348, states[0] = -86.816820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 390573130, states[0] = 18.279359, states[40]= 0.000002
Saving checkpoint... 
Iteration: 398642007, states[0] = -24.413316, states[40]= 0.000376
Saving checkpoint... 
Iteration: 406544949, states[0] = 28.453508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414424190, states[0] = -86.951165, states[40]= 0.000002
Saving checkpoint... 
Iteration: 422000190, states[0] = -63.654233, states[40]= 0.000002
Saving checkpoint... 
Iteration: 429927754, states[0] = -86.952957, states[40]= 0.000002
Saving checkpoint... 
Iteration: 437819539, states[0] = -86.797194, states[40]= 0.000002
Saving checkpoint... 
Iteration: 445562592, states[0] = 22.527603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453472472, states[0] = -86.977351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 461259699, states[0] = -86.573861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469075313, states[0] = 17.350560, states[40]= 0.000003
Saving checkpoint... 
Iteration: 476955651, states[0] = -86.967864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 484907005, states[0] = -86.932828, states[40]= 0.000002
Saving checkpoint... 
Iteration: 492785054, states[0] = -86.686218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500649131, states[0] = -30.083579, states[40]= 0.000483
Saving checkpoint... 
Iteration: 508309006, states[0] = -86.764924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515991010, states[0] = -86.981260, states[40]= 0.000002
Saving checkpoint... 
Iteration: 523950270, states[0] = -86.962285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 531661651, states[0] = -41.147638, states[40]= 0.000253
Saving checkpoint... 
Iteration: 539110160, states[0] = 0.187924, states[40]= 0.000094
Saving checkpoint... 
Iteration: 546703434, states[0] = -85.819046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554517167, states[0] = 31.294179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562273728, states[0] = -86.635643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570025992, states[0] = 31.897706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577434847, states[0] = -86.949718, states[40]= 0.000002
Saving checkpoint... 
Iteration: 585139053, states[0] = -22.079185, states[40]= 0.000291
Saving checkpoint... 
Iteration: 592736317, states[0] = -86.424777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600287220, states[0] = -86.688327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607740872, states[0] = -86.454683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615047595, states[0] = 27.692246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622824373, states[0] = -86.798642, states[40]= 0.000002
Saving checkpoint... 
Iteration: 630383126, states[0] = -86.899439, states[40]= 0.000002
Saving checkpoint... 
Iteration: 637840059, states[0] = -86.831890, states[40]= 0.000002
Saving checkpoint... 
Iteration: 645310880, states[0] = -86.762498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652755288, states[0] = -86.539187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660253851, states[0] = -86.530728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667765623, states[0] = -86.592045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 675351276, states[0] = -86.850583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 682831155, states[0] = -86.810774, states[40]= 0.000002
Saving checkpoint... 
Iteration: 690567155, states[0] = 20.746519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698446263, states[0] = -86.950238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 706112888, states[0] = -1.472174, states[40]= 0.000113
Saving checkpoint... 
Iteration: 713808634, states[0] = -86.752278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721353745, states[0] = -86.852256, states[40]= 0.000002
Saving checkpoint... 
Iteration: 728792433, states[0] = -86.699903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736212942, states[0] = -86.218400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743759424, states[0] = -86.556305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751405700, states[0] = -86.916741, states[40]= 0.000002
Saving checkpoint... 
Iteration: 759339529, states[0] = -86.824016, states[40]= 0.000002
Saving checkpoint... 
Iteration: 766977395, states[0] = -86.962043, states[40]= 0.000002
Saving checkpoint... 
Iteration: 774812625, states[0] = -86.760029, states[40]= 0.000002
Saving checkpoint... 
Iteration: 782435320, states[0] = -86.938627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 790166685, states[0] = -46.030356, states[40]= 0.000153
Saving checkpoint... 
Iteration: 797745979, states[0] = -86.476335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805732732, states[0] = -86.387107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813481145, states[0] = -86.961008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 821419595, states[0] = -86.924911, states[40]= 0.000002
Saving checkpoint... 
Iteration: 829178655, states[0] = -58.885251, states[40]= 0.000031
Saving checkpoint... 
Iteration: 837177781, states[0] = -57.863129, states[40]= 0.000036
Saving checkpoint... 
Iteration: 845086637, states[0] = 12.285535, states[40]= 0.000010
Saving checkpoint... 
Iteration: 852895653, states[0] = -86.901120, states[40]= 0.000002
Saving checkpoint... 
Iteration: 860626178, states[0] = -11.325463, states[40]= 0.000164
Saving checkpoint... 
Iteration: 868431334, states[0] = -86.931106, states[40]= 0.000002
Saving checkpoint... 
Iteration: 876404677, states[0] = -86.908804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 884202161, states[0] = -85.602629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892025730, states[0] = 31.917221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899721775, states[0] = -86.297050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907457267, states[0] = -86.944765, states[40]= 0.000002
Saving checkpoint... 
Iteration: 915052610, states[0] = 26.114454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922795429, states[0] = -86.699252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930645946, states[0] = -27.469403, states[40]= 0.000459
Saving checkpoint... 
Iteration: 938535725, states[0] = 30.667171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946354967, states[0] = -86.841704, states[40]= 0.000002
Saving checkpoint... 
Iteration: 954098472, states[0] = 6.558006, states[40]= 0.000034
Saving checkpoint... 
Iteration: 961687658, states[0] = -71.039323, states[40]= 0.000006
Saving checkpoint... 
Iteration: 969267015, states[0] = -86.581616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977146206, states[0] = -27.672542, states[40]= 0.000463
Saving checkpoint... 
Iteration: 984892841, states[0] = -86.890754, states[40]= 0.000002
Saving checkpoint... 
Iteration: 992572304, states[0] = 18.641238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1000290721, states[0] = -86.678470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008021246, states[0] = 31.879627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015619415, states[0] = -5.918473, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1023334914, states[0] = -86.799742, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1030975437, states[0] = -86.946557, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1038784735, states[0] = -86.654056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046469875, states[0] = -86.943244, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1054173457, states[0] = -53.022674, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1062074171, states[0] = 17.853622, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1069805811, states[0] = -86.723933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077905852, states[0] = -86.898689, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1085665853, states[0] = -45.166565, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1093797707, states[0] = -86.697185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101814505, states[0] = -86.746725, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1110279474, states[0] = -86.629021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119196822, states[0] = -83.360987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128243856, states[0] = -86.444056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137308290, states[0] = -86.727393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146328388, states[0] = -86.778583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1155549333, states[0] = 27.174008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164550208, states[0] = 26.899411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173611860, states[0] = -0.807256, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1182403240, states[0] = -86.890383, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1191121464, states[0] = -7.464893, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1200347079, states[0] = -86.813706, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1209178588, states[0] = -58.745970, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1218023771, states[0] = 31.967907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226887346, states[0] = -86.871109, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1235927520, states[0] = -86.907901, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1244983300, states[0] = -86.937871, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1253859752, states[0] = -86.832266, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1262612101, states[0] = -0.951237, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1271399118, states[0] = -86.881365, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1280087730, states[0] = 11.788123, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1288887708, states[0] = -86.868083, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1298336555, states[0] = -86.787760, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1307151932, states[0] = -32.350447, states[40]= 0.000457
Saving checkpoint... 
Iteration: 1315865639, states[0] = -86.837772, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1324598931, states[0] = 6.337890, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1333670677, states[0] = -50.044257, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1342400826, states[0] = -86.879098, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1351546151, states[0] = 28.133499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360238015, states[0] = -86.392288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369227018, states[0] = -86.311942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378076167, states[0] = 17.004193, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1386782026, states[0] = -86.623712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395535524, states[0] = 30.716313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404447873, states[0] = -86.911940, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1413370556, states[0] = -86.839386, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1422262991, states[0] = -86.536018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430917881, states[0] = -86.889569, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1439996880, states[0] = -86.931971, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1448883186, states[0] = -86.853819, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1457756764, states[0] = -86.501302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466483607, states[0] = -86.925704, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1475411752, states[0] = -86.881911, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1483818382, states[0] = -86.735441, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1492583532, states[0] = 13.732095, states[40]= 0.000007
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.805557
 - CaMKt in component CaMK (millimolar): 0.025027
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.070045
 - nass in component intracellular_ions (millimolar): 8.070197
 - ki in component intracellular_ions (millimolar): 143.323214
 - kss in component intracellular_ions (millimolar): 143.323176
 - cansr in component intracellular_ions (millimolar): 2.044968
 - cajsr in component intracellular_ions (millimolar): 1.979588
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008180
 - hf in component INa (dimensionless): 0.659737
 - hs in component INa (dimensionless): 0.659706
 - j in component INa (dimensionless): 0.659528
 - hsp in component INa (dimensionless): 0.411672
 - jp in component INa (dimensionless): 0.659400
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.455715
 - hLp in component INaL (dimensionless): 0.221670
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999462
 - iS in component Ito (dimensionless): 0.533154
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999462
 - iSp in component Ito (dimensionless): 0.576609
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.876445
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999608
 - jca in component ICaL (dimensionless): 0.999939
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003824
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.510101
 - xs1 in component IKs (dimensionless): 0.334634
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997030
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
11:46:32 (2508): called boinc_finish(0)

</stderr_txt>
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