𝕏

Task 55634090

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_431_0
Workunit 26417923
Created 1 Jul 2024, 15:46:44 UTC
Sent 2 Jul 2024, 5:43:54 UTC
Report deadline 5 Jul 2024, 5:43:54 UTC
Received 2 Jul 2024, 14:05:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237076
Run time 2 hours 0 min 42 sec
CPU time 2 hours 0 min 28 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.43 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.11 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_431.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_431_0_r165114222_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_431_0_r165114222_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 104.681262
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.084004
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032158
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.166851
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.940255
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037346
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8094152, states[0] = 13.111704, states[40]= 0.000005
Saving checkpoint... 
Iteration: 16061456, states[0] = 25.159685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24459375, states[0] = -86.917035, states[40]= 0.000002
Saving checkpoint... 
Iteration: 32672513, states[0] = -43.036841, states[40]= 0.000157
Saving checkpoint... 
Iteration: 40967670, states[0] = -86.951730, states[40]= 0.000002
Saving checkpoint... 
Iteration: 48667150, states[0] = -41.701720, states[40]= 0.000201
Saving checkpoint... 
Iteration: 56668417, states[0] = -44.307158, states[40]= 0.000159
Saving checkpoint... 
Iteration: 64870808, states[0] = -86.904467, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72940864, states[0] = -86.975763, states[40]= 0.000002
Saving checkpoint... 
Iteration: 80867537, states[0] = -86.912545, states[40]= 0.000002
Saving checkpoint... 
Iteration: 88875740, states[0] = -86.927650, states[40]= 0.000002
Saving checkpoint... 
Iteration: 96810754, states[0] = -86.809801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104874987, states[0] = -86.932639, states[40]= 0.000002
Saving checkpoint... 
Iteration: 113256267, states[0] = -86.607678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121514946, states[0] = 30.369123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129285938, states[0] = -86.739790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138003922, states[0] = 17.862836, states[40]= 0.834303
Saving checkpoint... 
Iteration: 146217195, states[0] = -86.351943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154226271, states[0] = -86.423783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162219441, states[0] = -86.371008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170367778, states[0] = -86.929224, states[40]= 0.000002
Saving checkpoint... 
Iteration: 178502143, states[0] = 24.115859, states[40]= 1.753868
Saving checkpoint... 
Iteration: 186803243, states[0] = -86.797446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195085145, states[0] = 12.822175, states[40]= 0.000009
Saving checkpoint... 
Iteration: 203021006, states[0] = 31.561967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210864687, states[0] = -86.923763, states[40]= 0.000002
Saving checkpoint... 
Iteration: 218758320, states[0] = -86.621113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226569705, states[0] = 19.590292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234552383, states[0] = 26.048522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242592186, states[0] = 9.460383, states[40]= 0.000020
Saving checkpoint... 
Iteration: 242716051, states[0] = -86.339839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250864939, states[0] = -86.922190, states[40]= 0.000002
Saving checkpoint... 
Iteration: 258703294, states[0] = -86.106882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266327032, states[0] = -86.854227, states[40]= 0.000002
Saving checkpoint... 
Iteration: 274066516, states[0] = 20.878705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281896129, states[0] = -86.957566, states[40]= 0.000002
Saving checkpoint... 
Iteration: 289811816, states[0] = -86.816305, states[40]= 0.000002
Saving checkpoint... 
Iteration: 297602473, states[0] = 4.201744, states[40]= 0.000053
Saving checkpoint... 
Iteration: 305474802, states[0] = -87.008022, states[40]= 0.000002
Saving checkpoint... 
Iteration: 313522183, states[0] = 31.637307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321173967, states[0] = -55.821236, states[40]= 0.000046
Saving checkpoint... 
Iteration: 328879966, states[0] = -86.937363, states[40]= 0.000002
Saving checkpoint... 
Iteration: 336968802, states[0] = -87.003722, states[40]= 0.000002
Saving checkpoint... 
Iteration: 344728626, states[0] = -86.432680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352476788, states[0] = -87.006191, states[40]= 0.000002
Saving checkpoint... 
Iteration: 360359920, states[0] = -86.908809, states[40]= 0.000002
Saving checkpoint... 
Iteration: 368188582, states[0] = -76.630586, states[40]= 0.000003
Saving checkpoint... 
Iteration: 375835726, states[0] = -86.866185, states[40]= 0.000002
Saving checkpoint... 
Iteration: 383451109, states[0] = -86.992529, states[40]= 0.000002
Saving checkpoint... 
Iteration: 390821534, states[0] = -86.834749, states[40]= 0.000002
Saving checkpoint... 
Iteration: 398483260, states[0] = -87.006119, states[40]= 0.000002
Saving checkpoint... 
Iteration: 406222580, states[0] = -86.383794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414011529, states[0] = 28.708999, states[40]= -0.000000
Saving checkpoint... 
Iteration: 421659905, states[0] = -41.009903, states[40]= 0.000244
Saving checkpoint... 
Iteration: 429204529, states[0] = -86.150428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436893929, states[0] = -86.946642, states[40]= 0.000002
Saving checkpoint... 
Iteration: 444349422, states[0] = -86.887384, states[40]= 0.000002
Saving checkpoint... 
Iteration: 451894401, states[0] = -86.946271, states[40]= 0.000002
Saving checkpoint... 
Iteration: 459408158, states[0] = -86.958731, states[40]= 0.000002
Saving checkpoint... 
Iteration: 467006212, states[0] = 23.442925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474639009, states[0] = -22.941516, states[40]= 0.000306
Saving checkpoint... 
Iteration: 482196601, states[0] = -84.951022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489823335, states[0] = -86.833279, states[40]= 0.000002
Saving checkpoint... 
Iteration: 497335155, states[0] = -86.858158, states[40]= 0.000002
Saving checkpoint... 
Iteration: 505040229, states[0] = 29.512647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512708697, states[0] = -86.244224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520318555, states[0] = -86.820280, states[40]= 0.000002
Saving checkpoint... 
Iteration: 528112642, states[0] = -1.739038, states[40]= 0.000116
Saving checkpoint... 
Iteration: 535795101, states[0] = -86.753504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543247681, states[0] = -86.544983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550778233, states[0] = -86.692119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558675013, states[0] = -57.005351, states[40]= 0.000039
Saving checkpoint... 
Iteration: 566081330, states[0] = 14.566006, states[40]= 0.000006
Saving checkpoint... 
Iteration: 573717169, states[0] = -86.330215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581064013, states[0] = 21.868873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588555828, states[0] = 24.887769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596258086, states[0] = -86.598529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603984534, states[0] = -86.995020, states[40]= 0.000002
Saving checkpoint... 
Iteration: 611900815, states[0] = -86.943512, states[40]= 0.000002
Saving checkpoint... 
Iteration: 619558350, states[0] = 23.993474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627203774, states[0] = -86.106257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635007796, states[0] = 25.621505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642715025, states[0] = -86.307437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650476431, states[0] = -86.989323, states[40]= 0.000002
Saving checkpoint... 
Iteration: 658243333, states[0] = -86.512459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666103337, states[0] = 3.747586, states[40]= 0.000057
Saving checkpoint... 
Iteration: 673815070, states[0] = -86.802888, states[40]= 0.000002
Saving checkpoint... 
Iteration: 681812156, states[0] = -86.794914, states[40]= 0.000002
Saving checkpoint... 
Iteration: 689678415, states[0] = -61.153593, states[40]= 0.000022
Saving checkpoint... 
Iteration: 697676229, states[0] = -58.432663, states[40]= 0.000032
Saving checkpoint... 
Iteration: 705486452, states[0] = -86.990016, states[40]= 0.000002
Saving checkpoint... 
Iteration: 713302404, states[0] = -86.765933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721200889, states[0] = -85.890357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729004744, states[0] = 20.102765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736661739, states[0] = -42.770677, states[40]= 0.000206
Saving checkpoint... 
Iteration: 744500891, states[0] = 36.133191, states[40]= 1.177042
Saving checkpoint... 
Iteration: 752241231, states[0] = -86.494018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760096186, states[0] = 7.488390, states[40]= 0.000029
Saving checkpoint... 
Iteration: 768095671, states[0] = 7.747767, states[40]= 0.000028
Saving checkpoint... 
Iteration: 775799877, states[0] = -86.754799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783573908, states[0] = 17.837226, states[40]= 0.000002
Saving checkpoint... 
Iteration: 791529805, states[0] = 31.360999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799308360, states[0] = -86.778024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807177821, states[0] = -60.377928, states[40]= 0.000025
Saving checkpoint... 
Iteration: 814767154, states[0] = -86.629725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822431131, states[0] = -86.955848, states[40]= 0.000002
Saving checkpoint... 
Iteration: 830269072, states[0] = -86.637482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838092609, states[0] = 9.267506, states[40]= 0.000020
Saving checkpoint... 
Iteration: 845747944, states[0] = -86.529021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853479989, states[0] = -86.979329, states[40]= 0.000002
Saving checkpoint... 
Iteration: 861208288, states[0] = -86.216680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868886830, states[0] = -86.914771, states[40]= 0.000002
Saving checkpoint... 
Iteration: 876599901, states[0] = 5.586721, states[40]= 0.000042
Saving checkpoint... 
Iteration: 884332701, states[0] = -86.831264, states[40]= 0.000002
Saving checkpoint... 
Iteration: 891990525, states[0] = -86.980977, states[40]= 0.000002
Saving checkpoint... 
Iteration: 899804437, states[0] = -86.761262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907733506, states[0] = -86.434310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915689634, states[0] = -78.140636, states[40]= 0.000002
Saving checkpoint... 
Iteration: 923798218, states[0] = -86.741240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932007681, states[0] = 25.495137, states[40]= -0.000000
Saving checkpoint... 
Iteration: 939890010, states[0] = -86.914194, states[40]= 0.000002
Saving checkpoint... 
Iteration: 947963433, states[0] = -86.966988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 956240208, states[0] = -86.475750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965251582, states[0] = -86.542688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974173335, states[0] = -55.002855, states[40]= 0.000050
Saving checkpoint... 
Iteration: 983214134, states[0] = -86.279212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992318559, states[0] = -86.793461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1001344951, states[0] = -86.848100, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1010569847, states[0] = 19.545406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019624294, states[0] = -10.443915, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1028598245, states[0] = 6.449981, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1037175582, states[0] = -57.603064, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1045880464, states[0] = -86.897495, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1055251441, states[0] = -86.536682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064185283, states[0] = -71.003496, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1073103377, states[0] = 3.742339, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1081563522, states[0] = 22.070346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090906694, states[0] = -86.921899, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1099515222, states[0] = 30.440157, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1108453080, states[0] = -86.952848, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1117277874, states[0] = -86.658229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126100713, states[0] = 5.170109, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1134688523, states[0] = -76.316342, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1143700321, states[0] = -85.788149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152835970, states[0] = -86.822637, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1161736918, states[0] = -86.442527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170571348, states[0] = 18.926978, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1179387152, states[0] = -86.897634, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1188412625, states[0] = -86.921483, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1197506137, states[0] = 23.317366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206139701, states[0] = -23.434779, states[40]= 0.000319
Saving checkpoint... 
Iteration: 1214959840, states[0] = -86.950283, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1223905293, states[0] = -86.913157, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1232394880, states[0] = -86.902773, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1240844588, states[0] = -86.833895, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1249470108, states[0] = -86.953052, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1258547104, states[0] = 27.709849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267425016, states[0] = -86.926578, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1276376139, states[0] = -86.879238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1285177333, states[0] = -59.686789, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1294032767, states[0] = 30.986492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302971426, states[0] = -86.950634, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1311717706, states[0] = -86.291535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320859837, states[0] = -86.854418, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1329215341, states[0] = -86.269987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337660839, states[0] = -41.817383, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1346482878, states[0] = -86.952752, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1355211861, states[0] = -86.234399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363833343, states[0] = -86.805400, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1372919236, states[0] = -86.916351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1381605932, states[0] = 2.340764, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1390148466, states[0] = -30.559449, states[40]= 0.000450
Saving checkpoint... 
Iteration: 1399268949, states[0] = -86.604309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408668126, states[0] = -49.236824, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1417811493, states[0] = -86.751336, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1426771131, states[0] = -86.612357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435837105, states[0] = -86.808859, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1444845645, states[0] = -86.824248, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1453655665, states[0] = -36.900328, states[40]= 0.000337
Saving checkpoint... 
Iteration: 1462603567, states[0] = 3.654906, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1471581843, states[0] = 14.357214, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1480459152, states[0] = -86.935036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1489643464, states[0] = -26.427124, states[40]= 0.000410
Saving checkpoint... 
Iteration: 1498580943, states[0] = 14.765532, states[40]= 0.000006
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.825814
 - CaMKt in component CaMK (millimolar): 0.025157
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.053397
 - nass in component intracellular_ions (millimolar): 8.053550
 - ki in component intracellular_ions (millimolar): 143.332892
 - kss in component intracellular_ions (millimolar): 143.332853
 - cansr in component intracellular_ions (millimolar): 2.054582
 - cajsr in component intracellular_ions (millimolar): 1.989962
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008163
 - hf in component INa (dimensionless): 0.660483
 - hs in component INa (dimensionless): 0.660454
 - j in component INa (dimensionless): 0.660285
 - hsp in component INa (dimensionless): 0.412484
 - jp in component INa (dimensionless): 0.660164
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.457015
 - hLp in component INaL (dimensionless): 0.223263
 - a in component Ito (dimensionless): 0.001075
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.535417
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999464
 - iSp in component Ito (dimensionless): 0.579270
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877701
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999621
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003862
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507120
 - xs1 in component IKs (dimensionless): 0.332838
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997025
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
12:04:54 (11652): called boinc_finish(0)

</stderr_txt>
]]>


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