𝕏

Task 55634084

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_231_0
Workunit 26417920
Created 1 Jul 2024, 15:46:44 UTC
Sent 2 Jul 2024, 5:43:54 UTC
Report deadline 5 Jul 2024, 5:43:54 UTC
Received 2 Jul 2024, 11:45:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237076
Run time 2 hours 1 min 42 sec
CPU time 2 hours 1 min 22 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.43 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.11 MB
Peak swap size 6.25 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_231.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_231_0_r1961699445_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_231_0_r1961699445_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 104.615489
     * GNaL_b in INaL: 0.006078
     * Gto_b in Ito: 0.085807
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031729
     * GKs_b in IKs: 0.001903
     * GK1_b in IK1: 0.161499
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.657373
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036902
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7852627, states[0] = -86.725242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16054983, states[0] = 27.419494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24207736, states[0] = -79.386184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 32386964, states[0] = -86.819476, states[40]= 0.000002
Saving checkpoint... 
Iteration: 40628746, states[0] = -7.983367, states[40]= 0.000166
Saving checkpoint... 
Iteration: 48495051, states[0] = -86.923028, states[40]= 0.000002
Saving checkpoint... 
Iteration: 56739977, states[0] = -86.404282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64862900, states[0] = -86.840286, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72971001, states[0] = -86.943048, states[40]= 0.000002
Saving checkpoint... 
Iteration: 81093495, states[0] = 9.595997, states[40]= 0.000021
Saving checkpoint... 
Iteration: 89026919, states[0] = 31.665384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96987372, states[0] = -86.964351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 105194197, states[0] = -79.677430, states[40]= 0.000002
Saving checkpoint... 
Iteration: 113601863, states[0] = 5.013833, states[40]= 0.000053
Saving checkpoint... 
Iteration: 121753427, states[0] = -86.529251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129945656, states[0] = -86.952643, states[40]= 0.000002
Saving checkpoint... 
Iteration: 138896171, states[0] = -86.914256, states[40]= 0.000002
Saving checkpoint... 
Iteration: 147300219, states[0] = -86.733061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155371727, states[0] = -86.885973, states[40]= 0.000002
Saving checkpoint... 
Iteration: 163500112, states[0] = -73.219367, states[40]= 0.000002
Saving checkpoint... 
Iteration: 171929094, states[0] = -86.943691, states[40]= 0.000002
Saving checkpoint... 
Iteration: 180128496, states[0] = -13.439903, states[40]= 0.000194
Saving checkpoint... 
Iteration: 188101188, states[0] = 5.103696, states[40]= 0.000054
Saving checkpoint... 
Iteration: 196408376, states[0] = -86.926490, states[40]= 0.000002
Saving checkpoint... 
Iteration: 204571307, states[0] = 18.992727, states[40]= 0.000002
Saving checkpoint... 
Iteration: 212483960, states[0] = -86.971686, states[40]= 0.000002
Saving checkpoint... 
Iteration: 220562460, states[0] = 22.494707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228365870, states[0] = -86.875939, states[40]= 0.000002
Saving checkpoint... 
Iteration: 236332446, states[0] = -86.815965, states[40]= 0.000002
Saving checkpoint... 
Iteration: 244445016, states[0] = -86.951377, states[40]= 0.000002
Saving checkpoint... 
Iteration: 253757163, states[0] = -86.550100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262521699, states[0] = 31.475259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271247455, states[0] = -86.493505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279805286, states[0] = -86.744437, states[40]= 0.000002
Saving checkpoint... 
Iteration: 288403687, states[0] = -86.917504, states[40]= 0.000002
Saving checkpoint... 
Iteration: 297077203, states[0] = 16.481277, states[40]= 0.000004
Saving checkpoint... 
Iteration: 305439203, states[0] = -86.944347, states[40]= 0.000002
Saving checkpoint... 
Iteration: 313961229, states[0] = -86.956278, states[40]= 0.000002
Saving checkpoint... 
Iteration: 322665526, states[0] = -45.144499, states[40]= 0.000203
Saving checkpoint... 
Iteration: 331387684, states[0] = -86.898332, states[40]= 0.000002
Saving checkpoint... 
Iteration: 340114363, states[0] = -2.562167, states[40]= 0.000147
Saving checkpoint... 
Iteration: 348714085, states[0] = -86.234887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357401205, states[0] = -86.911077, states[40]= 0.000002
Saving checkpoint... 
Iteration: 366108185, states[0] = 1.243004, states[40]= 0.000098
Saving checkpoint... 
Iteration: 374831664, states[0] = -86.806278, states[40]= 0.000002
Saving checkpoint... 
Iteration: 383439689, states[0] = -86.940074, states[40]= 0.000002
Saving checkpoint... 
Iteration: 392175262, states[0] = -55.367706, states[40]= 0.000060
Saving checkpoint... 
Iteration: 400964030, states[0] = -86.952533, states[40]= 0.000002
Saving checkpoint... 
Iteration: 409617174, states[0] = -4.481309, states[40]= 0.000168
Saving checkpoint... 
Iteration: 418298574, states[0] = -86.715339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426937711, states[0] = -86.936269, states[40]= 0.000002
Saving checkpoint... 
Iteration: 435758199, states[0] = -86.544817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444759005, states[0] = -86.548552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453434183, states[0] = -86.932378, states[40]= 0.000002
Saving checkpoint... 
Iteration: 461962472, states[0] = -86.948212, states[40]= 0.000002
Saving checkpoint... 
Iteration: 470752382, states[0] = -86.510558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479416485, states[0] = -86.917625, states[40]= 0.000002
Saving checkpoint... 
Iteration: 487947865, states[0] = -86.938893, states[40]= 0.000002
Saving checkpoint... 
Iteration: 496461745, states[0] = -86.945821, states[40]= 0.000002
Saving checkpoint... 
Iteration: 505084404, states[0] = 13.265012, states[40]= 0.000010
Saving checkpoint... 
Iteration: 513781391, states[0] = -86.647639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522789084, states[0] = -86.676482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531266773, states[0] = -86.582421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539808526, states[0] = -86.738474, states[40]= 0.000002
Saving checkpoint... 
Iteration: 548538864, states[0] = 29.770785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557442179, states[0] = -86.931428, states[40]= 0.000002
Saving checkpoint... 
Iteration: 566185313, states[0] = -68.033624, states[40]= 0.000011
Saving checkpoint... 
Iteration: 575217282, states[0] = -86.253718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583641149, states[0] = -23.881914, states[40]= 0.000421
Saving checkpoint... 
Iteration: 592308802, states[0] = -86.736160, states[40]= 0.000002
Saving checkpoint... 
Iteration: 601347070, states[0] = -86.823527, states[40]= 0.000002
Saving checkpoint... 
Iteration: 609963178, states[0] = -86.939855, states[40]= 0.000002
Saving checkpoint... 
Iteration: 618527105, states[0] = 31.484691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627267414, states[0] = -86.579714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 635861838, states[0] = -86.846125, states[40]= 0.000002
Saving checkpoint... 
Iteration: 644353373, states[0] = -86.832004, states[40]= 0.000002
Saving checkpoint... 
Iteration: 652717368, states[0] = -86.249733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660807319, states[0] = -86.727784, states[40]= 0.000002
Saving checkpoint... 
Iteration: 668967300, states[0] = -86.938370, states[40]= 0.000002
Saving checkpoint... 
Iteration: 677255042, states[0] = -86.513081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685544450, states[0] = 28.413876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693562048, states[0] = 22.655362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701854486, states[0] = -86.830490, states[40]= 0.000002
Saving checkpoint... 
Iteration: 710270444, states[0] = -86.588909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718325217, states[0] = -86.771317, states[40]= 0.000002
Saving checkpoint... 
Iteration: 726432122, states[0] = -86.914905, states[40]= 0.000002
Saving checkpoint... 
Iteration: 734893649, states[0] = -86.881119, states[40]= 0.000002
Saving checkpoint... 
Iteration: 743264977, states[0] = -86.560957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751449119, states[0] = -86.924130, states[40]= 0.000002
Saving checkpoint... 
Iteration: 759493737, states[0] = -86.943590, states[40]= 0.000002
Saving checkpoint... 
Iteration: 767481417, states[0] = -86.938601, states[40]= 0.000002
Saving checkpoint... 
Iteration: 775833637, states[0] = -86.786736, states[40]= 0.000002
Saving checkpoint... 
Iteration: 784137136, states[0] = -20.696342, states[40]= 0.000291
Saving checkpoint... 
Iteration: 792242493, states[0] = -86.430973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800374271, states[0] = -86.854179, states[40]= 0.000002
Saving checkpoint... 
Iteration: 808457337, states[0] = -86.925277, states[40]= 0.000002
Saving checkpoint... 
Iteration: 816300733, states[0] = -86.698543, states[40]= 0.000002
Saving checkpoint... 
Iteration: 824158912, states[0] = -38.738631, states[40]= 0.000370
Saving checkpoint... 
Iteration: 832031014, states[0] = 31.132354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839790715, states[0] = -86.663436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847628579, states[0] = -13.545786, states[40]= 0.000193
Saving checkpoint... 
Iteration: 855503318, states[0] = 17.081068, states[40]= 1.176135
Saving checkpoint... 
Iteration: 863286672, states[0] = -86.647212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871288599, states[0] = -86.653879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879182043, states[0] = -63.420080, states[40]= 0.000020
Saving checkpoint... 
Iteration: 887075027, states[0] = 17.433946, states[40]= 0.000003
Saving checkpoint... 
Iteration: 894831758, states[0] = -86.775639, states[40]= 0.000002
Saving checkpoint... 
Iteration: 902679073, states[0] = -59.688929, states[40]= 0.000034
Saving checkpoint... 
Iteration: 910482233, states[0] = -86.930557, states[40]= 0.000002
Saving checkpoint... 
Iteration: 918382449, states[0] = -86.857594, states[40]= 0.000002
Saving checkpoint... 
Iteration: 926385109, states[0] = -86.860293, states[40]= 0.000002
Saving checkpoint... 
Iteration: 934311747, states[0] = -86.724104, states[40]= 0.000002
Saving checkpoint... 
Iteration: 941800525, states[0] = -86.690400, states[40]= 0.000002
Saving checkpoint... 
Iteration: 949506003, states[0] = 22.941781, states[40]= -0.000000
Saving checkpoint... 
Iteration: 957184661, states[0] = -66.995540, states[40]= 0.000012
Saving checkpoint... 
Iteration: 964821097, states[0] = -86.746755, states[40]= 0.000002
Saving checkpoint... 
Iteration: 972598587, states[0] = 6.445641, states[40]= 0.000042
Saving checkpoint... 
Iteration: 980230724, states[0] = -86.338154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987940202, states[0] = -86.904877, states[40]= 0.000002
Saving checkpoint... 
Iteration: 995359483, states[0] = -86.821232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1002895142, states[0] = -86.866906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1010353819, states[0] = -86.811122, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1017806231, states[0] = -86.703332, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1025298785, states[0] = -86.679819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032607698, states[0] = 1.554600, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1040486125, states[0] = -86.924420, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1047938906, states[0] = -86.900549, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1055678544, states[0] = -59.032212, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1063202285, states[0] = -85.644602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070807451, states[0] = -86.703784, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1078410121, states[0] = -86.876938, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1086153290, states[0] = -33.692485, states[40]= 0.000516
Saving checkpoint... 
Iteration: 1093806129, states[0] = -86.698519, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1101251506, states[0] = -86.467406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109275365, states[0] = -86.586875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116916243, states[0] = -86.879913, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1124412560, states[0] = -86.876355, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1131973555, states[0] = -86.913977, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1139547531, states[0] = 27.561513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146965211, states[0] = -86.909325, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1154737078, states[0] = -86.372894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162635459, states[0] = -19.304959, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1170388655, states[0] = -86.850001, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1178045074, states[0] = 28.257014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185908723, states[0] = -86.869370, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1193816291, states[0] = -86.720921, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1201611422, states[0] = -0.641315, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1209305575, states[0] = -86.690003, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1217263163, states[0] = -86.523421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1225053365, states[0] = 25.743827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232753372, states[0] = -86.470157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240537861, states[0] = 30.000267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248426108, states[0] = -86.879916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1256517278, states[0] = 30.859401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264136788, states[0] = -20.374406, states[40]= 0.000279
Saving checkpoint... 
Iteration: 1272003466, states[0] = 17.089628, states[40]= 1.105857
Saving checkpoint... 
Iteration: 1279622654, states[0] = -8.565967, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1287548199, states[0] = 27.368511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295365788, states[0] = -86.813125, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1303066159, states[0] = 21.087830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310856221, states[0] = -86.797377, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1318486442, states[0] = -86.908230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1326289650, states[0] = -86.630561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333976571, states[0] = -86.903423, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1341968403, states[0] = -86.899376, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1349818886, states[0] = -86.718349, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1357469310, states[0] = -86.898878, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1365150909, states[0] = -31.637519, states[40]= 0.000554
Saving checkpoint... 
Iteration: 1372781683, states[0] = -86.597388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380509196, states[0] = 26.819793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388312507, states[0] = -86.699211, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1396222032, states[0] = -86.244975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404059178, states[0] = 23.731718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411881974, states[0] = -86.827935, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1419609729, states[0] = 0.391626, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1427465561, states[0] = -86.893044, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1435092682, states[0] = 9.394032, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1442739599, states[0] = -86.372498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450520021, states[0] = 31.344403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458308187, states[0] = -86.682864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1466296910, states[0] = -86.647408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474164883, states[0] = -44.370485, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1481896715, states[0] = -86.840356, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1489924642, states[0] = -86.864640, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1497777086, states[0] = -86.570968, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.778119
 - CaMKt in component CaMK (millimolar): 0.025486
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.106861
 - nass in component intracellular_ions (millimolar): 8.107016
 - ki in component intracellular_ions (millimolar): 143.255488
 - kss in component intracellular_ions (millimolar): 143.255449
 - cansr in component intracellular_ions (millimolar): 2.078051
 - cajsr in component intracellular_ions (millimolar): 2.014935
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.008202
 - hf in component INa (dimensionless): 0.658724
 - hs in component INa (dimensionless): 0.658693
 - j in component INa (dimensionless): 0.658518
 - hsp in component INa (dimensionless): 0.410582
 - jp in component INa (dimensionless): 0.658391
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.454920
 - hLp in component INaL (dimensionless): 0.221229
 - a in component Ito (dimensionless): 0.001078
 - iF in component Ito (dimensionless): 0.999460
 - iS in component Ito (dimensionless): 0.533278
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999460
 - iSp in component Ito (dimensionless): 0.576754
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877029
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999614
 - jca in component ICaL (dimensionless): 0.999939
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003959
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.509396
 - xs1 in component IKs (dimensionless): 0.334062
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997037
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
10:55:29 (3252): called boinc_finish(0)

</stderr_txt>
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