𝕏

Task 55633303

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_130_1
Workunit 26417529
Created 1 Jul 2024, 15:46:23 UTC
Sent 2 Jul 2024, 5:42:26 UTC
Report deadline 5 Jul 2024, 5:42:26 UTC
Received 2 Jul 2024, 14:31:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 17 min 39 sec
CPU time 2 hours 12 min 56 sec
Validate state Valid
Credit 43.21
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.46 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_130.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_130_1_r586336791_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_5000-conf_130_1_r586336791_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.347722
     * GNaL_b in INaL: 0.005706
     * Gto_b in Ito: 0.081063
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031825
     * GKs_b in IKs: 0.001943
     * GK1_b in IK1: 0.160038
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.355488
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031732
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11122758, states[0] = -94.044617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22284178, states[0] = -93.944717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33453972, states[0] = -93.939072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44549831, states[0] = -93.895899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55529343, states[0] = -93.894626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66580304, states[0] = -93.895585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77734358, states[0] = -93.274143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88737716, states[0] = -93.903943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99886626, states[0] = -93.880266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111026672, states[0] = -93.911500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122173806, states[0] = -93.882324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133339006, states[0] = -93.917630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144504259, states[0] = -93.884493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155635128, states[0] = -93.911975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166802913, states[0] = -93.887802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177971454, states[0] = -93.861640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189109712, states[0] = -93.891827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200242716, states[0] = -93.345667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211385642, states[0] = -93.897835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222515610, states[0] = 31.887424, states[40]= 0.008423
Saving checkpoint... 
Iteration: 233566561, states[0] = -93.909255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244543492, states[0] = -93.883561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255680285, states[0] = -93.915536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266808901, states[0] = -93.887413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277932839, states[0] = -93.832620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289107986, states[0] = -93.891630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300227604, states[0] = -93.048579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311314686, states[0] = -93.899888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322435947, states[0] = -93.878698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333572536, states[0] = -93.908812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344745936, states[0] = -93.880698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355834944, states[0] = -93.917067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366959999, states[0] = -93.884590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378106064, states[0] = -93.907488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389166033, states[0] = -93.890101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400130224, states[0] = -16.127666, states[40]= 0.001778
Saving checkpoint... 
Iteration: 411273094, states[0] = -93.901107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422429014, states[0] = -93.878573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433595943, states[0] = -93.907691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444527091, states[0] = -93.883408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455715066, states[0] = -93.916742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466870245, states[0] = -93.885904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477987596, states[0] = -93.870230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489146463, states[0] = -93.890350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500305263, states[0] = -93.607422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511370313, states[0] = -93.897710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522515283, states[0] = 31.864515, states[40]= 0.009429
Saving checkpoint... 
Iteration: 533631512, states[0] = -93.906103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544778230, states[0] = -93.879939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555841609, states[0] = -93.916542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566969556, states[0] = -93.884055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578111013, states[0] = -93.907875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589204243, states[0] = -93.888887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600353406, states[0] = -93.725884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611470759, states[0] = -93.894548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622576134, states[0] = 15.253802, states[40]= 0.001493
Saving checkpoint... 
Iteration: 633729566, states[0] = -93.902223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644888144, states[0] = -93.878557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656017076, states[0] = -93.910401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667114739, states[0] = -93.881739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678279914, states[0] = -93.917150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689434176, states[0] = -93.884391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700614404, states[0] = -93.908143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711796461, states[0] = -93.886791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722733869, states[0] = -93.261354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733850019, states[0] = -93.897926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745054684, states[0] = 23.228926, states[40]= 0.000489
Saving checkpoint... 
Iteration: 756202367, states[0] = -93.902984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767360914, states[0] = -93.878605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778502383, states[0] = -93.910747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789616568, states[0] = -93.881480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800649567, states[0] = -93.912123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811752494, states[0] = -93.887463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822739908, states[0] = -93.325862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833869865, states[0] = -93.897107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845026692, states[0] = 31.096798, states[40]= 0.000280
Saving checkpoint... 
Iteration: 856174462, states[0] = -93.903838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867244155, states[0] = -93.879718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878203972, states[0] = -93.915534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889351674, states[0] = -93.885426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900459200, states[0] = -93.852175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911563559, states[0] = -93.891520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922681345, states[0] = -54.918909, states[40]= 0.000116
Saving checkpoint... 
Iteration: 933866095, states[0] = -93.897034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945029474, states[0] = 30.575057, states[40]= 0.000185
Saving checkpoint... 
Iteration: 956185594, states[0] = -93.903227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967345605, states[0] = -93.878385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978540958, states[0] = -93.908837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989780179, states[0] = -93.879064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000985265, states[0] = -93.910989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012160392, states[0] = -93.880475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023377599, states[0] = -93.914716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034434907, states[0] = -93.883718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045515916, states[0] = -93.882267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056683399, states[0] = -93.888441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067880917, states[0] = -93.771250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079048706, states[0] = -93.891575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090182741, states[0] = -56.008207, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1101378305, states[0] = -93.896332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112567250, states[0] = 18.690441, states[40]= 0.000967
Saving checkpoint... 
Iteration: 1123684157, states[0] = -93.902961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134830369, states[0] = -93.878228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146000573, states[0] = -93.910116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157154441, states[0] = -93.880275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168202302, states[0] = -93.914912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179362195, states[0] = -93.884683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190408273, states[0] = -93.806232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201589711, states[0] = -93.890320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212618836, states[0] = -7.014314, states[40]= 0.003137
Saving checkpoint... 
Iteration: 1223786123, states[0] = -93.899105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234975143, states[0] = -93.876573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246132575, states[0] = -93.904701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257302751, states[0] = -93.878297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268467342, states[0] = -93.911166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279646747, states[0] = -93.880140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290795074, states[0] = -93.915888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301961026, states[0] = -93.882783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313127839, states[0] = -93.908780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324287929, states[0] = -93.885783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335467192, states[0] = -93.856676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346321521, states[0] = -93.897681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357420742, states[0] = -93.876864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368536047, states[0] = -93.908288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379744527, states[0] = -93.878732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390873540, states[0] = -93.914132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402075794, states[0] = -93.880870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413281890, states[0] = -93.915740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424454227, states[0] = -93.882658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435620376, states[0] = -93.907578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446790981, states[0] = -93.885490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457969934, states[0] = -93.858180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469126705, states[0] = -93.888929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480346596, states[0] = -93.710658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491534894, states[0] = -93.891141, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.751809
 - CaMKt in component CaMK (millimolar): 0.001584
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.721877
 - nass in component intracellular_ions (millimolar): 6.722002
 - ki in component intracellular_ions (millimolar): 145.139641
 - kss in component intracellular_ions (millimolar): 145.139631
 - cansr in component intracellular_ions (millimolar): 1.835885
 - cajsr in component intracellular_ions (millimolar): 1.835736
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004064
 - hf in component INa (dimensionless): 0.858569
 - hs in component INa (dimensionless): 0.858570
 - j in component INa (dimensionless): 0.858572
 - hsp in component INa (dimensionless): 0.686700
 - jp in component INa (dimensionless): 0.858573
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697816
 - hLp in component INaL (dimensionless): 0.502198
 - a in component Ito (dimensionless): 0.000674
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.997547
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999148
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998698
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005440
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002209
 - xs1 in component IKs (dimensionless): 0.024459
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997623
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:18:29 (11337): called boinc_finish(0)

</stderr_txt>
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