𝕏

Task 55633268

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_330_0
Workunit 26417512
Created 1 Jul 2024, 15:46:18 UTC
Sent 2 Jul 2024, 5:43:54 UTC
Report deadline 5 Jul 2024, 5:43:54 UTC
Received 2 Jul 2024, 11:57:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237076
Run time 1 hours 57 min 46 sec
CPU time 1 hours 57 min 45 sec
Validate state Valid
Credit 44.34
Device peak FLOPS 3.43 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.10 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_330.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_330_0_r1147438973_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_ENDO_3000-conf_330_0_r1147438973_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.855133
     * GNaL_b in INaL: 0.006227
     * Gto_b in Ito: 0.087753
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031436
     * GKs_b in IKs: 0.001886
     * GK1_b in IK1: 0.164999
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.002888
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031878
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7984085, states[0] = -94.160851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16347019, states[0] = -94.107191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24265947, states[0] = -93.693493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32353739, states[0] = -94.069701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40230714, states[0] = -94.046470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48308052, states[0] = -93.783547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56368305, states[0] = -94.054434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64156850, states[0] = -94.041599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72157582, states[0] = -37.149360, states[40]= 0.001249
Saving checkpoint... 
Iteration: 80133429, states[0] = -94.049510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88059906, states[0] = -94.044536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95845198, states[0] = -94.033079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103741255, states[0] = -93.515237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111744704, states[0] = -94.054025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119652759, states[0] = -94.040211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127524536, states[0] = 31.117416, states[40]= 0.000459
Saving checkpoint... 
Iteration: 135495741, states[0] = -94.015889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143408030, states[0] = -94.050313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151258043, states[0] = -94.035828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159223917, states[0] = -93.197837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167034243, states[0] = -94.030032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174964832, states[0] = -94.047914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182973534, states[0] = -94.028300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190848157, states[0] = -93.869339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198819197, states[0] = -94.052834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206245514, states[0] = -94.053556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213916502, states[0] = -94.049704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221618001, states[0] = -94.041203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229339013, states[0] = -94.032556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237071958, states[0] = 16.677650, states[40]= 0.001123
Saving checkpoint... 
Iteration: 244677637, states[0] = -52.952675, states[40]= 0.000153
Saving checkpoint... 
Iteration: 252237392, states[0] = -93.491968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259716988, states[0] = -91.914258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267389858, states[0] = -93.933129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274908121, states[0] = -93.953876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282445671, states[0] = -93.986585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289826349, states[0] = -93.823217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297328924, states[0] = -93.829139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305210202, states[0] = -94.052703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312618797, states[0] = -94.046554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320411899, states[0] = -94.049527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328313535, states[0] = -94.033139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335944116, states[0] = -94.028697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343780032, states[0] = -93.684914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351399550, states[0] = -93.944337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359255493, states[0] = -94.053076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366979126, states[0] = -94.046668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374761859, states[0] = -94.034905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382308711, states[0] = -94.033140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389976758, states[0] = -94.027509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397757383, states[0] = -93.591608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405681964, states[0] = -94.051354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413274578, states[0] = -94.052825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421248954, states[0] = -94.035248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429034972, states[0] = 29.057909, states[40]= 0.000150
Saving checkpoint... 
Iteration: 436947175, states[0] = -93.987165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444922758, states[0] = -94.048709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452796712, states[0] = -94.033350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460730805, states[0] = -93.429617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468395764, states[0] = -93.939601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476459960, states[0] = -94.047114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484546167, states[0] = 25.846847, states[40]= 0.000268
Saving checkpoint... 
Iteration: 492347552, states[0] = -93.867198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499976338, states[0] = -94.005097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508144225, states[0] = -94.039169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516183072, states[0] = -57.386993, states[40]= 0.000076
Saving checkpoint... 
Iteration: 523998270, states[0] = -94.015661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531926339, states[0] = -94.048289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539799072, states[0] = -94.032983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547970466, states[0] = -94.001688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555738551, states[0] = -94.052372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563674105, states[0] = -94.037757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571492552, states[0] = -94.026446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579340230, states[0] = -93.852566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586976612, states[0] = -94.004963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594859839, states[0] = -94.050449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602593320, states[0] = -94.041015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610791638, states[0] = -93.724844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618501745, states[0] = -94.016843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626176580, states[0] = -94.050375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633887706, states[0] = -94.049399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641687812, states[0] = -94.036948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649483342, states[0] = -94.026471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657345846, states[0] = -93.863411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664979662, states[0] = -94.006326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672704834, states[0] = -94.051370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680638982, states[0] = -94.038832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688383849, states[0] = -94.029523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696056847, states[0] = 22.265379, states[40]= 0.000497
Saving checkpoint... 
Iteration: 703974561, states[0] = -94.003473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711640287, states[0] = -94.047530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719347488, states[0] = -94.050416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727250519, states[0] = -94.034200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735177881, states[0] = -53.147569, states[40]= 0.000149
Saving checkpoint... 
Iteration: 743429976, states[0] = -94.047464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751478356, states[0] = -94.026293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759292484, states[0] = -93.727154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767713554, states[0] = -94.035511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776061898, states[0] = -94.035370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784825579, states[0] = -93.819791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794228086, states[0] = -94.051483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803546989, states[0] = -94.042357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813267489, states[0] = -93.633990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822860704, states[0] = -94.049687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832727291, states[0] = -93.353337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841939822, states[0] = -93.980421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851459814, states[0] = -94.045911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860721870, states[0] = -94.034883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869908822, states[0] = -94.028107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879478915, states[0] = -94.005242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888769036, states[0] = -94.051331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898041493, states[0] = -94.042290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907718112, states[0] = -92.286519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916955052, states[0] = -93.991024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926075143, states[0] = -94.037717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935563631, states[0] = -94.041214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944551631, states[0] = -94.041702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953879646, states[0] = -94.028807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962826415, states[0] = -94.030628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972118907, states[0] = -7.348531, states[40]= 0.002997
Saving checkpoint... 
Iteration: 981992552, states[0] = -94.044118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991388455, states[0] = -94.028390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000624597, states[0] = -11.861769, states[40]= 0.002200
Saving checkpoint... 
Iteration: 1009974358, states[0] = -94.002373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019531296, states[0] = -94.042337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029146115, states[0] = -28.552012, states[40]= 0.002404
Saving checkpoint... 
Iteration: 1038278794, states[0] = -93.677999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047452946, states[0] = -93.989195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056753978, states[0] = -94.050828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066398555, states[0] = -94.027811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075715282, states[0] = -91.119361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084651507, states[0] = -32.541798, states[40]= 0.001934
Saving checkpoint... 
Iteration: 1094217064, states[0] = -94.050321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103651083, states[0] = -94.036963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112887448, states[0] = -94.028031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122388467, states[0] = -93.928614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131445394, states[0] = -93.983638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140701182, states[0] = -94.049749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150038802, states[0] = -94.041593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159460438, states[0] = -94.025526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168439646, states[0] = -94.026149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177541943, states[0] = 27.143222, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1186651532, states[0] = -32.560019, states[40]= 0.001931
Saving checkpoint... 
Iteration: 1195603250, states[0] = 2.724314, states[40]= 0.003496
Saving checkpoint... 
Iteration: 1204303017, states[0] = -94.030693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213363372, states[0] = -94.028524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222342934, states[0] = -94.029205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231068250, states[0] = -94.040063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240096035, states[0] = -94.038842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249290401, states[0] = -94.031012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258397525, states[0] = -94.027225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267453258, states[0] = -94.025401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276737631, states[0] = -93.490063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285597132, states[0] = 5.862537, states[40]= 0.003066
Saving checkpoint... 
Iteration: 1294503321, states[0] = 36.508042, states[40]= 0.591181
Saving checkpoint... 
Iteration: 1303490844, states[0] = -94.024133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312318235, states[0] = -94.029793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321208434, states[0] = -94.033928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330430917, states[0] = -94.025904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339392844, states[0] = -94.027119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348318088, states[0] = -94.029682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357154966, states[0] = -94.035984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365985263, states[0] = -94.043188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374948513, states[0] = -94.044686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383925876, states[0] = -94.045560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392785028, states[0] = -94.049565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401590180, states[0] = -94.038941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410204198, states[0] = -78.722780, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1418855980, states[0] = -94.028116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427436109, states[0] = -94.045016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436089261, states[0] = -94.038674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444602294, states[0] = 3.236395, states[40]= 0.003440
Saving checkpoint... 
Iteration: 1453258713, states[0] = -94.031543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461947994, states[0] = -94.044427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470555281, states[0] = -94.031561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479250837, states[0] = -93.557891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488015118, states[0] = 31.423139, states[40]= 0.010081
Saving checkpoint... 
Iteration: 1496964576, states[0] = -94.024308, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.899183
 - CaMKt in component CaMK (millimolar): 0.003146
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.751434
 - nass in component intracellular_ions (millimolar): 6.751556
 - ki in component intracellular_ions (millimolar): 145.099691
 - kss in component intracellular_ions (millimolar): 145.099680
 - cansr in component intracellular_ions (millimolar): 1.839159
 - cajsr in component intracellular_ions (millimolar): 1.838969
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004004
 - hf in component INa (dimensionless): 0.861484
 - hs in component INa (dimensionless): 0.861486
 - j in component INa (dimensionless): 0.861493
 - hsp in component INa (dimensionless): 0.691891
 - jp in component INa (dimensionless): 0.861497
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.702012
 - hLp in component INaL (dimensionless): 0.503833
 - a in component Ito (dimensionless): 0.000667
 - iF in component Ito (dimensionless): 0.999845
 - iS in component Ito (dimensionless): 0.968567
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999845
 - iSp in component Ito (dimensionless): 0.984046
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.989970
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005056
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030211
 - xs1 in component IKs (dimensionless): 0.073675
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997588
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:24:51 (8092): called boinc_finish(0)

</stderr_txt>
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