𝕏

Task 55631469

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_428_1
Workunit 26416613
Created 1 Jul 2024, 15:45:35 UTC
Sent 2 Jul 2024, 5:22:45 UTC
Report deadline 5 Jul 2024, 5:22:45 UTC
Received 3 Jul 2024, 6:10:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 15 min 3 sec
CPU time 1 hours 2 min 10 sec
Validate state Valid
Credit 43.04
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.59 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_428.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_428_1_r1150931871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_428_1_r1150931871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.964775
     * GNaL_b in INaL: 0.005584
     * Gto_b in Ito: 0.088077
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032070
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.165274
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.290896
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033271
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10741799, states[0] = -94.215057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23858775, states[0] = -94.195021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 37039735, states[0] = -94.187093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49316784, states[0] = -94.199086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61630624, states[0] = -94.210922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72779635, states[0] = -81.627388, states[40]= 0.000005
Saving checkpoint... 
Iteration: 83948241, states[0] = -94.226548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95950253, states[0] = -94.245298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108320654, states[0] = -94.249854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 119528912, states[0] = -94.226273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132203639, states[0] = -94.226437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143794911, states[0] = -94.243461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156371327, states[0] = -94.242273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169271264, states[0] = -94.234469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181309258, states[0] = -94.245075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192309608, states[0] = -94.229193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204625658, states[0] = -94.230896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217704583, states[0] = -27.868435, states[40]= 0.005332
Saving checkpoint... 
Iteration: 231486293, states[0] = -94.241093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244324122, states[0] = -94.234694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255164584, states[0] = -11.379373, states[40]= 0.000599
Saving checkpoint... 
Iteration: 266944026, states[0] = -94.232978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278917928, states[0] = -94.242618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290549708, states[0] = -94.216219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303381623, states[0] = -94.257287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316635451, states[0] = -94.237511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328811260, states[0] = -94.245126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341339165, states[0] = -94.244244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353667544, states[0] = -94.249239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366382628, states[0] = -94.242860, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378352232, states[0] = -94.256886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390965403, states[0] = -94.254983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403228724, states[0] = -94.253446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415158968, states[0] = -8.211494, states[40]= 0.000543
Saving checkpoint... 
Iteration: 428067660, states[0] = -94.222613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440471345, states[0] = -94.161942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453044343, states[0] = -94.212359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465827607, states[0] = -94.256088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477878074, states[0] = -94.014490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490384374, states[0] = -94.029249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503199594, states[0] = -94.250189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514674572, states[0] = -94.228506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 527022136, states[0] = -94.229910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540114920, states[0] = 10.304179, states[40]= 0.000038
Saving checkpoint... 
Iteration: 552113500, states[0] = -94.228738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564793292, states[0] = -94.227118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576329481, states[0] = -94.242457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588822085, states[0] = -94.242553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601767868, states[0] = -94.232690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614025544, states[0] = -94.237209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626497083, states[0] = -94.237744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640115886, states[0] = 9.945319, states[40]= 0.000042
Saving checkpoint... 
Iteration: 653185046, states[0] = -94.247316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665490379, states[0] = -94.176664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677417114, states[0] = -94.225323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689877781, states[0] = -94.225447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701731074, states[0] = -94.232414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712939710, states[0] = -94.123927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725255606, states[0] = -62.751061, states[40]= 0.000076
Saving checkpoint... 
Iteration: 738009075, states[0] = -94.189739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750303460, states[0] = -93.738741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761771625, states[0] = -94.231215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773411866, states[0] = -94.252764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786305195, states[0] = -94.241288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798754774, states[0] = -94.242649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811090607, states[0] = -94.247639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 823596075, states[0] = -94.247357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835968939, states[0] = -94.250971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848100106, states[0] = -94.229609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860660997, states[0] = -94.242296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873462781, states[0] = -94.250794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 886581514, states[0] = -94.233597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897893971, states[0] = -94.046468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911504401, states[0] = -94.235056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924583665, states[0] = -94.225739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937264438, states[0] = -94.224035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948799802, states[0] = -94.240006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961307233, states[0] = -94.239683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973331931, states[0] = -94.251630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986068100, states[0] = -94.246795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998235291, states[0] = -94.248619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009179606, states[0] = -94.230603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020715000, states[0] = -94.246987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032704020, states[0] = -27.695485, states[40]= 0.005333
Saving checkpoint... 
Iteration: 1045167149, states[0] = -12.868611, states[40]= 0.000642
Saving checkpoint... 
Iteration: 1057684921, states[0] = -21.154270, states[40]= 0.003045
Saving checkpoint... 
Iteration: 1069362572, states[0] = -94.227123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081386716, states[0] = -94.236444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094185313, states[0] = -94.229747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1105774664, states[0] = -94.249481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117526954, states[0] = 33.630560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130347606, states[0] = -93.921155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141841928, states[0] = -94.226778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154906656, states[0] = -94.221160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168186017, states[0] = -94.242880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181293638, states[0] = -94.238128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1194304253, states[0] = -94.226876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207625331, states[0] = 6.424915, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1220979343, states[0] = -94.247302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234077204, states[0] = -94.230612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246129485, states[0] = -94.242570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260165367, states[0] = -11.839129, states[40]= 0.000609
Saving checkpoint... 
Iteration: 1272100401, states[0] = -94.222497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285851703, states[0] = -94.248884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299156367, states[0] = -94.228467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311596601, states[0] = -94.229527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1325243113, states[0] = -52.299805, states[40]= 0.000377
Saving checkpoint... 
Iteration: 1336900367, states[0] = -94.224236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349228416, states[0] = -94.226733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360152829, states[0] = -4.973608, states[40]= 0.000466
Saving checkpoint... 
Iteration: 1372862826, states[0] = -93.966121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385171466, states[0] = -15.285519, states[40]= 0.000810
Saving checkpoint... 
Iteration: 1397860868, states[0] = -93.960241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410262010, states[0] = -69.468001, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1422668276, states[0] = -13.507834, states[40]= 0.000671
Saving checkpoint... 
Iteration: 1433846574, states[0] = -94.234407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445359565, states[0] = -93.955985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458792291, states[0] = -94.235716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471552198, states[0] = -94.229044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483964881, states[0] = -94.230922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495075458, states[0] = 24.684122, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.093581
 - CaMKt in component CaMK (millimolar): 0.001790
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.769783
 - nass in component intracellular_ions (millimolar): 7.769936
 - ki in component intracellular_ions (millimolar): 144.044620
 - kss in component intracellular_ions (millimolar): 144.044605
 - cansr in component intracellular_ions (millimolar): 1.802005
 - cajsr in component intracellular_ions (millimolar): 1.803549
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003926
 - hf in component INa (dimensionless): 0.865252
 - hs in component INa (dimensionless): 0.865252
 - j in component INa (dimensionless): 0.865253
 - hsp in component INa (dimensionless): 0.698652
 - jp in component INa (dimensionless): 0.865254
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707341
 - hLp in component INaL (dimensionless): 0.513506
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997234
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999046
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998070
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004424
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002405
 - xs1 in component IKs (dimensionless): 0.032241
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997541
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:13:01 (30548): called boinc_finish(0)

</stderr_txt>
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