𝕏

Task 55631465

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_28_1
Workunit 26416611
Created 1 Jul 2024, 15:45:35 UTC
Sent 2 Jul 2024, 5:22:45 UTC
Report deadline 5 Jul 2024, 5:22:45 UTC
Received 3 Jul 2024, 4:32:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 17 min 45 sec
CPU time 1 hours 3 min 33 sec
Validate state Valid
Credit 45.20
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.60 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_28.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_28_1_r822403337_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_5000-conf_28_1_r822403337_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.970814
     * GNaL_b in INaL: 0.005764
     * Gto_b in Ito: 0.083886
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032059
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.164094
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.797554
     * GKb_b in IKb: 0.003793
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11968528, states[0] = -94.211564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22621305, states[0] = 11.204508, states[40]= 0.000026
Saving checkpoint... 
Iteration: 34573805, states[0] = -94.201445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 46733690, states[0] = -94.214482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58449665, states[0] = -94.243349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70748606, states[0] = -94.249263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82818177, states[0] = -93.787343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94667735, states[0] = -94.233599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107618064, states[0] = 9.690020, states[40]= 0.000044
Saving checkpoint... 
Iteration: 120171829, states[0] = -14.207773, states[40]= 0.000758
Saving checkpoint... 
Iteration: 131442650, states[0] = -94.252889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142217615, states[0] = -94.241889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154452323, states[0] = -94.245638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168024575, states[0] = -94.216219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180055680, states[0] = 30.849667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192688757, states[0] = -21.890623, states[40]= 0.003724
Saving checkpoint... 
Iteration: 205371855, states[0] = -94.011734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217894065, states[0] = -94.064259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229360852, states[0] = -94.248729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241159467, states[0] = -94.264942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252566594, states[0] = 27.706988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264324959, states[0] = -94.249212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273945968, states[0] = -94.256636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285856761, states[0] = -94.272358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 296893363, states[0] = -94.248040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309075894, states[0] = -94.253433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320149885, states[0] = -3.152797, states[40]= 0.000407
Saving checkpoint... 
Iteration: 333386768, states[0] = -94.271770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344391126, states[0] = -94.247712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357656622, states[0] = -6.449354, states[40]= 0.000512
Saving checkpoint... 
Iteration: 370351286, states[0] = -93.951138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383088981, states[0] = -94.244817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394976261, states[0] = -94.241945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407933410, states[0] = -94.131303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420504387, states[0] = -94.203299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431836040, states[0] = -94.247765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444256438, states[0] = -94.248914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454896049, states[0] = -94.241894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467819269, states[0] = -93.826829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480142342, states[0] = 0.105421, states[40]= 0.000276
Saving checkpoint... 
Iteration: 491529951, states[0] = -94.252905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502907555, states[0] = -94.088958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514800993, states[0] = -94.242020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 527020168, states[0] = -94.244524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539317869, states[0] = -94.247110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550806964, states[0] = -94.269915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563020721, states[0] = -94.212783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574379482, states[0] = -94.245903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 585504445, states[0] = -94.201908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597367301, states[0] = -94.240844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609156682, states[0] = -94.249266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619755844, states[0] = -94.241457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631120025, states[0] = -94.263129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643753425, states[0] = -94.258864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654751745, states[0] = -94.241186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666922541, states[0] = -94.244515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679064576, states[0] = -94.250523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 690566010, states[0] = -94.234021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702674559, states[0] = -16.369040, states[40]= 0.000981
Saving checkpoint... 
Iteration: 714491874, states[0] = -94.243231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727335019, states[0] = -94.239935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739099877, states[0] = -94.249263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752361936, states[0] = -94.239536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764182791, states[0] = -94.247434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775420199, states[0] = -94.108220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787809570, states[0] = -93.778390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799593213, states[0] = -94.241370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810499630, states[0] = -94.196462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821165426, states[0] = -94.260045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832557903, states[0] = 30.243614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844035767, states[0] = -94.249722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856454443, states[0] = -94.251516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867320785, states[0] = -94.238821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879390661, states[0] = -94.243103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891875467, states[0] = -94.243208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905795900, states[0] = -94.266645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919046272, states[0] = -94.248841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931146249, states[0] = -94.259700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942479640, states[0] = -94.237184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954143776, states[0] = -94.246523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965871209, states[0] = -94.266485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976772220, states[0] = -94.244040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988371222, states[0] = -94.266290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000262925, states[0] = -67.822232, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1010903212, states[0] = -94.265709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022684961, states[0] = -20.738284, states[40]= 0.002843
Saving checkpoint... 
Iteration: 1035389931, states[0] = -94.049069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048036011, states[0] = -94.217210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059486764, states[0] = -94.240301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071269860, states[0] = -94.254670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082832497, states[0] = -93.877183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094437896, states[0] = -94.240606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106198909, states[0] = -94.256527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118109125, states[0] = -94.244243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1130682980, states[0] = -94.257623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142343625, states[0] = -94.236275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155874707, states[0] = -94.264810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167607004, states[0] = 13.395788, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1179805347, states[0] = -94.236221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1191262760, states[0] = -94.253842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203429873, states[0] = -94.263562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215250188, states[0] = -56.108171, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1227748817, states[0] = -55.011732, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1238612921, states[0] = -94.258096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1250262896, states[0] = -67.775590, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1260976118, states[0] = -94.261984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274132814, states[0] = -94.243965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286190925, states[0] = -94.255218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297854303, states[0] = -93.952616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310645211, states[0] = -94.250452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324160213, states[0] = -94.243002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336991058, states[0] = -94.237843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349335569, states[0] = -94.239821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360653465, states[0] = -94.251447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372505746, states[0] = 24.365066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384413476, states[0] = -94.238415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396631435, states[0] = -94.242931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407943148, states[0] = -94.135638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419326689, states[0] = -94.239349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432343797, states[0] = -94.233760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443796458, states[0] = -94.250664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455647312, states[0] = -94.249571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467374101, states[0] = -94.233254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479799673, states[0] = -94.233662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492619677, states[0] = 8.724285, states[40]= 0.000054
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.108216
 - CaMKt in component CaMK (millimolar): 0.001780
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.749762
 - nass in component intracellular_ions (millimolar): 7.749914
 - ki in component intracellular_ions (millimolar): 144.067388
 - kss in component intracellular_ions (millimolar): 144.067374
 - cansr in component intracellular_ions (millimolar): 1.794838
 - cajsr in component intracellular_ions (millimolar): 1.796288
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003920
 - hf in component INa (dimensionless): 0.865532
 - hs in component INa (dimensionless): 0.865532
 - j in component INa (dimensionless): 0.865533
 - hsp in component INa (dimensionless): 0.699158
 - jp in component INa (dimensionless): 0.865534
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707746
 - hLp in component INaL (dimensionless): 0.513994
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997223
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999042
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998051
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004375
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002411
 - xs1 in component IKs (dimensionless): 0.032439
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997538
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
20:56:15 (29708): called boinc_finish(0)

</stderr_txt>
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