𝕏

Task 55623807

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1
Workunit 26412784
Created 1 Jul 2024, 15:42:10 UTC
Sent 2 Jul 2024, 4:31:54 UTC
Report deadline 5 Jul 2024, 4:31:54 UTC
Received 5 Jul 2024, 0:22:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241509
Run time 3 hours 3 min 45 sec
CPU time 2 hours 34 min 52 sec
Validate state Valid
Credit 48.25
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.48 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1_r1628644069_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1_r1628644069_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 100.424480
     * GNaL_b in INaL: 0.005575
     * Gto_b in Ito: 0.080830
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032049
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.160699
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.423052
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029189
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18952082, states[0] = -94.549733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40223748, states[0] = -94.168788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61483972, states[0] = -94.604424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77099462, states[0] = -8.883631, states[40]= 0.001603
Saving checkpoint... 
Iteration: 91105476, states[0] = -16.808166, states[40]= 0.001423
Saving checkpoint... 
Iteration: 104507749, states[0] = 19.089015, states[40]= 0.000003
Saving checkpoint... 
Iteration: 115521461, states[0] = 23.380723, states[40]= -0.000000
Saving checkpoint... 
Iteration: 129796821, states[0] = -94.502985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142570374, states[0] = 12.374695, states[40]= 0.000114
Saving checkpoint... 
Iteration: 153854274, states[0] = -94.586412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165767778, states[0] = -94.428967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178768795, states[0] = -94.431643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192531660, states[0] = 23.680516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205288051, states[0] = -94.482231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218741740, states[0] = -94.327009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231774527, states[0] = -94.445184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243822845, states[0] = -94.544350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254690711, states[0] = -93.983251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271421916, states[0] = -94.619720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284848177, states[0] = -94.572124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298055496, states[0] = 18.744735, states[40]= 0.000009
Saving checkpoint... 
Iteration: 311651875, states[0] = -78.249387, states[40]= 0.000014
Saving checkpoint... 
Iteration: 325146802, states[0] = -69.962087, states[40]= 0.000045
Saving checkpoint... 
Iteration: 338919174, states[0] = -94.613316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352159325, states[0] = -89.992761, states[40]= 0.000002
Saving checkpoint... 
Iteration: 363835707, states[0] = -94.551817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377556553, states[0] = 18.370089, states[40]= 0.000012
Saving checkpoint... 
Iteration: 390925959, states[0] = -94.611443, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1_r1628644069_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1_r1628644069_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 100.424480
     * GNaL_b in INaL: 0.005575
     * Gto_b in Ito: 0.080830
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032049
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.160699
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.423052
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029189
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 390925959
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.611443 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 404394433, states[0] = -94.597162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417617634, states[0] = -32.641352, states[40]= 0.002219
Saving checkpoint... 
Iteration: 431510162, states[0] = 20.473466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445803765, states[0] = -94.496350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459241991, states[0] = -94.308670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472430128, states[0] = -94.606209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485955370, states[0] = -94.611242, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1_r1628644069_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_1000-conf_521_1_r1628644069_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 100.424480
     * GNaL_b in INaL: 0.005575
     * Gto_b in Ito: 0.080830
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032049
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.160699
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.423052
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029189
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 485955370
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.611242 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 499526971, states[0] = 23.738885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513602167, states[0] = -13.750299, states[40]= 0.001632
Saving checkpoint... 
Iteration: 526192834, states[0] = -93.980072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539874859, states[0] = -94.574282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553441014, states[0] = -94.602633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566998591, states[0] = -94.609893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577947114, states[0] = -94.602084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587548241, states[0] = 20.999790, states[40]= 0.000002
Saving checkpoint... 
Iteration: 598263934, states[0] = -94.382802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609868489, states[0] = -94.563918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621204036, states[0] = -94.066224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633874662, states[0] = -94.566522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647224208, states[0] = -94.201053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659089516, states[0] = -0.092908, states[40]= 0.001288
Saving checkpoint... 
Iteration: 671374349, states[0] = -94.563282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685286444, states[0] = -94.439689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699099883, states[0] = -10.929072, states[40]= 0.001759
Saving checkpoint... 
Iteration: 712503885, states[0] = 13.085879, states[40]= 1.525897
Saving checkpoint... 
Iteration: 725332389, states[0] = -94.518411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738709238, states[0] = -94.095545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752443227, states[0] = -94.587150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765102239, states[0] = -13.817188, states[40]= 0.001621
Saving checkpoint... 
Iteration: 778623215, states[0] = -39.451235, states[40]= 0.001588
Saving checkpoint... 
Iteration: 791741211, states[0] = -94.277811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805063748, states[0] = 15.490233, states[40]= 0.000040
Saving checkpoint... 
Iteration: 818558844, states[0] = 17.524835, states[40]= 0.000017
Saving checkpoint... 
Iteration: 831622951, states[0] = -39.117939, states[40]= 0.001623
Saving checkpoint... 
Iteration: 845176865, states[0] = -93.783330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855058884, states[0] = 17.510532, states[40]= 0.000017
Saving checkpoint... 
Iteration: 861367936, states[0] = -94.543178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866511274, states[0] = 20.950736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887948428, states[0] = -94.577380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909509987, states[0] = 20.398414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931180903, states[0] = -93.827481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954548583, states[0] = 20.917874, states[40]= 0.000002
Saving checkpoint... 
Iteration: 966370131, states[0] = -94.536354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976612620, states[0] = -26.536802, states[40]= 0.002078
Saving checkpoint... 
Iteration: 993460543, states[0] = -94.571217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007344112, states[0] = -94.509383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024913927, states[0] = -94.555999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041825571, states[0] = -94.483634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059028456, states[0] = 23.771071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076183150, states[0] = -93.839963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093208538, states[0] = -94.061082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113444483, states[0] = -94.558334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136274251, states[0] = -94.370804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159228431, states[0] = -94.182924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174429849, states[0] = -94.549478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182131587, states[0] = -49.965503, states[40]= 0.000601
Saving checkpoint... 
Iteration: 1193243662, states[0] = -94.255892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203677640, states[0] = -93.763952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212313438, states[0] = -94.451267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221359032, states[0] = -94.506688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232748308, states[0] = -94.272656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244273141, states[0] = -94.358755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255410191, states[0] = -94.535886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266827861, states[0] = -94.468571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273614625, states[0] = -28.927241, states[40]= 0.002209
Saving checkpoint... 
Iteration: 1279213810, states[0] = -94.082905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285715453, states[0] = -94.093473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296538368, states[0] = 23.057999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305396854, states[0] = -94.525674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313876469, states[0] = -94.512849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327351914, states[0] = -94.491507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337386533, states[0] = -94.517405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342726363, states[0] = -94.156140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350586312, states[0] = 2.532407, states[40]= 0.000932
Saving checkpoint... 
Iteration: 1362276100, states[0] = -94.357593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369910629, states[0] = -94.526869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381383412, states[0] = -94.512001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391053073, states[0] = 19.595080, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1407200614, states[0] = -93.973572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423110110, states[0] = -23.463019, states[40]= 0.001789
Saving checkpoint... 
Iteration: 1439446831, states[0] = -94.532585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457446467, states[0] = -94.531055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475546079, states[0] = 21.575350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490157765, states[0] = -87.872434, states[40]= 0.000003
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.410670
 - CaMKt in component CaMK (millimolar): 0.027998
 - cass in component intracellular_ions (millimolar): 0.000108
 - nai in component intracellular_ions (millimolar): 7.917208
 - nass in component intracellular_ions (millimolar): 7.917383
 - ki in component intracellular_ions (millimolar): 143.048281
 - kss in component intracellular_ions (millimolar): 143.048243
 - cansr in component intracellular_ions (millimolar): 3.271848
 - cajsr in component intracellular_ions (millimolar): 3.251285
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.003802
 - hf in component INa (dimensionless): 0.871213
 - hs in component INa (dimensionless): 0.871211
 - j in component INa (dimensionless): 0.871187
 - hsp in component INa (dimensionless): 0.709491
 - jp in component INa (dimensionless): 0.871165
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.696709
 - hLp in component INaL (dimensionless): 0.437258
 - a in component Ito (dimensionless): 0.000644
 - iF in component Ito (dimensionless): 0.999858
 - iS in component Ito (dimensionless): 0.999858
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999858
 - iSp in component Ito (dimensionless): 0.999858
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916517
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999864
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006801
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330640
 - xs1 in component IKs (dimensionless): 0.271690
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997463
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:21:53 (7874): called boinc_finish(0)

</stderr_txt>
]]>


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