𝕏

Task 55623276

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_220_0
Workunit 26412521
Created 1 Jul 2024, 15:41:59 UTC
Sent 2 Jul 2024, 4:31:54 UTC
Report deadline 5 Jul 2024, 4:31:58 UTC
Received 5 Jul 2024, 6:03:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241509
Run time 3 hours 0 min 32 sec
CPU time 2 hours 13 min 46 sec
Validate state Valid
Credit 45.87
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.61 MB
Peak swap size 32.57 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_220.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_220_0_r1252290642_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_220_0_r1252290642_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.477380
     * GNaL_b in INaL: 0.006057
     * Gto_b in Ito: 0.080851
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032085
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.162640
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.303681
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030030
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13571698, states[0] = -84.513880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25596529, states[0] = -84.576882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33998676, states[0] = -84.732390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45438097, states[0] = -21.750993, states[40]= 0.000194
Saving checkpoint... 
Iteration: 56840690, states[0] = -83.951336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68228615, states[0] = -84.410575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79932853, states[0] = -84.574090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93566851, states[0] = -84.430264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106024518, states[0] = 31.466820, states[40]= 0.002324
Saving checkpoint... 
Iteration: 117545345, states[0] = -84.291134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131133835, states[0] = -48.987695, states[40]= 0.000034
Saving checkpoint... 
Iteration: 145197587, states[0] = -84.170073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158571660, states[0] = -84.437244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172102263, states[0] = -11.652635, states[40]= 0.000280
Saving checkpoint... 
Iteration: 184578392, states[0] = -84.463905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198573040, states[0] = -84.433236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211388702, states[0] = 21.320228, states[40]= 0.000013
Saving checkpoint... 
Iteration: 226051670, states[0] = 23.449177, states[40]= 0.000009
Saving checkpoint... 
Iteration: 239028007, states[0] = 31.887434, states[40]= 0.007147
Saving checkpoint... 
Iteration: 252068054, states[0] = 15.877788, states[40]= 0.000036
Saving checkpoint... 
Iteration: 265529268, states[0] = -84.099668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279015200, states[0] = 36.324761, states[40]= 0.822668
Saving checkpoint... 
Iteration: 292630867, states[0] = -84.632820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304078192, states[0] = 11.743309, states[40]= 0.000070
Saving checkpoint... 
Iteration: 308341560, states[0] = -84.721431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317641768, states[0] = -84.656436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326204678, states[0] = -84.149354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338605878, states[0] = -84.545026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349278500, states[0] = -84.564533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352155819, states[0] = -61.486076, states[40]= 0.000006
Saving checkpoint... 
Iteration: 360082030, states[0] = 11.154146, states[40]= 0.000077
Saving checkpoint... 
Iteration: 371731066, states[0] = 20.820546, states[40]= 0.000014
Saving checkpoint... 
Iteration: 379495509, states[0] = -67.773629, states[40]= 0.000003
Saving checkpoint... 
Iteration: 390980795, states[0] = -84.659425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400769284, states[0] = -0.943379, states[40]= 0.000283
Saving checkpoint... 
Iteration: 416892503, states[0] = -84.276626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432830556, states[0] = -66.526674, states[40]= 0.000003
Saving checkpoint... 
Iteration: 449334794, states[0] = -84.694750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467620221, states[0] = -84.570391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485897733, states[0] = -84.287508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500713028, states[0] = 30.989685, states[40]= 0.001100
Saving checkpoint... 
Iteration: 513542869, states[0] = -84.105367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530860794, states[0] = -83.829408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551447718, states[0] = -4.558534, states[40]= 0.000321
Saving checkpoint... 
Iteration: 571347464, states[0] = -84.703742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589761212, states[0] = 10.563413, states[40]= 0.000084
Saving checkpoint... 
Iteration: 601203088, states[0] = -83.976413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618025264, states[0] = -84.716913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634730538, states[0] = 27.147616, states[40]= 0.000027
Saving checkpoint... 
Iteration: 653933072, states[0] = -84.442875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674702193, states[0] = 36.414675, states[40]= 1.018987
Saving checkpoint... 
Iteration: 694316505, states[0] = -84.620780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710523891, states[0] = -80.973089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726789753, states[0] = -4.493115, states[40]= 0.000321
Saving checkpoint... 
Iteration: 743464904, states[0] = -12.472672, states[40]= 0.000269
Saving checkpoint... 
Iteration: 763535479, states[0] = -83.590067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784219282, states[0] = -84.062616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802298045, states[0] = -84.543075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809610730, states[0] = -84.454983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 821490159, states[0] = -36.424566, states[40]= 0.000124
Saving checkpoint... 
Iteration: 823186515, states[0] = -70.579890, states[40]= 0.000002
Saving checkpoint... 
Iteration: 838618903, states[0] = -84.485109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854089912, states[0] = 20.130797, states[40]= 0.000016
Saving checkpoint... 
Iteration: 871489850, states[0] = -33.371952, states[40]= 0.000154
Saving checkpoint... 
Iteration: 893623480, states[0] = -84.491785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915243484, states[0] = -84.211617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920730194, states[0] = 31.752713, states[40]= 0.004285
Saving checkpoint... 
Iteration: 937372046, states[0] = -84.705768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948338541, states[0] = -84.638861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963998155, states[0] = -84.618660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 979516749, states[0] = -57.000220, states[40]= 0.000012
Saving checkpoint... 
Iteration: 994920318, states[0] = -84.255662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010995145, states[0] = -84.603043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026575262, states[0] = -84.152195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044650473, states[0] = -84.562128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066309578, states[0] = -84.531188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084945702, states[0] = -84.385986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089250875, states[0] = -84.197314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098049778, states[0] = -84.707007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099343957, states[0] = -84.630268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099396779, states[0] = 30.764782, states[40]= 0.106284
Saving checkpoint... 
Iteration: 1099452107, states[0] = 11.288544, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1107598197, states[0] = -84.291633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117901353, states[0] = -84.041534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131561710, states[0] = -83.940429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139008545, states[0] = -84.619222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142252889, states[0] = -84.191492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147349579, states[0] = -84.637097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156824658, states[0] = -19.105109, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1164435886, states[0] = 21.553128, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1172941541, states[0] = -84.333953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182796880, states[0] = 6.983118, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1191167573, states[0] = -27.962492, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1204473212, states[0] = 1.283612, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1222113221, states[0] = 17.635865, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1237748105, states[0] = 31.407306, states[40]= 0.002061
Saving checkpoint... 
Iteration: 1240254608, states[0] = -84.163473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252647949, states[0] = -84.510418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261263259, states[0] = -84.222590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278546270, states[0] = -75.234907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296139307, states[0] = 4.814882, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1306569495, states[0] = -83.914744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317508251, states[0] = -29.088661, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1337848900, states[0] = -35.966478, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1352137896, states[0] = 7.466979, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1366487858, states[0] = -3.983515, states[40]= 0.000318
Saving checkpoint... 
Iteration: 1377840312, states[0] = -24.328848, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1392650449, states[0] = -84.489005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411112963, states[0] = 22.487911, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1428980805, states[0] = -84.467502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439675621, states[0] = -84.570618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453929771, states[0] = -84.140642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464519860, states[0] = -33.741809, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1480000239, states[0] = -84.533796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1491761434, states[0] = 31.275026, states[40]= 0.001649
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.581275
 - CaMKt in component CaMK (millimolar): 0.038787
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.779464
 - nass in component intracellular_ions (millimolar): 6.779619
 - ki in component intracellular_ions (millimolar): 144.885197
 - kss in component intracellular_ions (millimolar): 144.885169
 - cansr in component intracellular_ions (millimolar): 2.048205
 - cajsr in component intracellular_ions (millimolar): 1.802281
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010226
 - hf in component INa (dimensionless): 0.573622
 - hs in component INa (dimensionless): 0.573468
 - j in component INa (dimensionless): 0.572630
 - hsp in component INa (dimensionless): 0.326482
 - jp in component INa (dimensionless): 0.571937
 - mL in component INaL (dimensionless): 0.000352
 - hL in component INaL (dimensionless): 0.346672
 - hLp in component INaL (dimensionless): 0.151100
 - a in component Ito (dimensionless): 0.001250
 - iF in component Ito (dimensionless): 0.999206
 - iS in component Ito (dimensionless): 0.365455
 - ap in component Ito (dimensionless): 0.000637
 - iFp in component Ito (dimensionless): 0.999206
 - iSp in component Ito (dimensionless): 0.399679
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.841941
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995676
 - jca in component ICaL (dimensionless): 0.998098
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005891
 - xrf in component IKr (dimensionless): 0.000408
 - xrs in component IKr (dimensionless): 0.674889
 - xs1 in component IKs (dimensionless): 0.387021
 - xs2 in component IKs (dimensionless): 0.000280
 - xk1 in component IK1 (dimensionless): 0.996781
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:03:13 (8002): called boinc_finish(0)

</stderr_txt>
]]>


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