𝕏

Task 55623274

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_20_0
Workunit 26412520
Created 1 Jul 2024, 15:41:59 UTC
Sent 2 Jul 2024, 4:31:54 UTC
Report deadline 5 Jul 2024, 4:31:58 UTC
Received 3 Jul 2024, 14:55:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241509
Run time 3 hours 34 min 27 sec
CPU time 3 hours 5 min 15 sec
Validate state Valid
Credit 46.17
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.60 MB
Peak swap size 32.57 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_20.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_20_0_r517791979_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_20_0_r517791979_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.193896
     * GNaL_b in INaL: 0.005625
     * Gto_b in Ito: 0.084138
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031828
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.159297
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.513559
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033742
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6759459, states[0] = -9.447851, states[40]= 0.001664
Saving checkpoint... 
Iteration: 13206683, states[0] = -84.299797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19668159, states[0] = 16.030951, states[40]= 0.011463
Saving checkpoint... 
Iteration: 26065302, states[0] = 11.150598, states[40]= 0.000092
Saving checkpoint... 
Iteration: 35783688, states[0] = -35.784069, states[40]= 0.000137
Saving checkpoint... 
Iteration: 48906403, states[0] = -84.437076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62774959, states[0] = -24.954236, states[40]= 0.000193
Saving checkpoint... 
Iteration: 73793403, states[0] = -44.460846, states[40]= 0.000058
Saving checkpoint... 
Iteration: 83681684, states[0] = 31.187104, states[40]= 0.046179
Saving checkpoint... 
Iteration: 95050430, states[0] = 20.764515, states[40]= 0.000014
Saving checkpoint... 
Iteration: 106993656, states[0] = -84.692278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117889938, states[0] = -84.331431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130864606, states[0] = -84.141913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143127001, states[0] = -41.102623, states[40]= 0.000081
Saving checkpoint... 
Iteration: 154128141, states[0] = -41.745978, states[40]= 0.000076
Saving checkpoint... 
Iteration: 167843744, states[0] = -83.822396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182218509, states[0] = -84.278269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196791620, states[0] = -36.012912, states[40]= 0.000129
Saving checkpoint... 
Iteration: 210525934, states[0] = -84.056620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224480575, states[0] = -58.909670, states[40]= 0.000009
Saving checkpoint... 
Iteration: 233120219, states[0] = -28.872994, states[40]= 0.000183
Saving checkpoint... 
Iteration: 242657539, states[0] = -84.673113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251170380, states[0] = -82.163536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258985465, states[0] = -84.660538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266545797, states[0] = -84.201900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274077374, states[0] = 11.227505, states[40]= 0.000075
Saving checkpoint... 
Iteration: 281996187, states[0] = -84.678422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289648418, states[0] = -84.648787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 296712762, states[0] = 27.350691, states[40]= 0.000036
Saving checkpoint... 
Iteration: 304599389, states[0] = -84.497859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312342677, states[0] = -84.697491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319844896, states[0] = -83.292615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326653869, states[0] = -84.655724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333211394, states[0] = -84.165640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340256186, states[0] = -84.445732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351320235, states[0] = -84.651855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365381555, states[0] = 27.878899, states[40]= 0.000055
Saving checkpoint... 
Iteration: 379334238, states[0] = -84.675933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393933385, states[0] = -84.479960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407617388, states[0] = -84.543937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421974808, states[0] = -84.613673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435466102, states[0] = -31.534617, states[40]= 0.000169
Saving checkpoint... 
Iteration: 449257052, states[0] = -84.420950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463100957, states[0] = 2.423668, states[40]= 0.000219
Saving checkpoint... 
Iteration: 477514449, states[0] = -81.911416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491227389, states[0] = -84.224180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505325518, states[0] = -84.643184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519336403, states[0] = -84.663778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533230037, states[0] = -84.227546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545140435, states[0] = -33.907752, states[40]= 0.000149
Saving checkpoint... 
Iteration: 558195727, states[0] = -83.776064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572551228, states[0] = -84.114432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586940471, states[0] = -84.464333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601096798, states[0] = 9.450460, states[40]= 0.000097
Saving checkpoint... 
Iteration: 615115430, states[0] = -2.876405, states[40]= 0.000303
Saving checkpoint... 
Iteration: 629077611, states[0] = 20.519899, states[40]= 0.000015
Saving checkpoint... 
Iteration: 642696741, states[0] = -84.696542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654367481, states[0] = 36.759705, states[40]= 0.951203
Saving checkpoint... 
Iteration: 668254158, states[0] = -84.340019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685402427, states[0] = 25.834504, states[40]= 0.000014
Saving checkpoint... 
Iteration: 702612953, states[0] = -84.461888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722734366, states[0] = 27.227497, states[40]= 0.000033
Saving checkpoint... 
Iteration: 743365535, states[0] = -84.689719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764460501, states[0] = -6.857624, states[40]= 0.000319
Saving checkpoint... 
Iteration: 776483998, states[0] = -32.443965, states[40]= 0.000162
Saving checkpoint... 
Iteration: 792890258, states[0] = -84.061167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809484312, states[0] = -30.986182, states[40]= 0.000173
Saving checkpoint... 
Iteration: 826656719, states[0] = -84.591268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843727433, states[0] = 31.375732, states[40]= 0.002924
Saving checkpoint... 
Iteration: 863737204, states[0] = 28.884316, states[40]= 0.000133
Saving checkpoint... 
Iteration: 885191791, states[0] = -73.148288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906330467, states[0] = -84.597814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921634282, states[0] = -84.499989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 935714546, states[0] = 36.017281, states[40]= 0.659729
Saving checkpoint... 
Iteration: 949401512, states[0] = 30.944393, states[40]= 0.001374
Saving checkpoint... 
Iteration: 960199124, states[0] = -77.338652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975052255, states[0] = 32.316290, states[40]= 0.610776
Saving checkpoint... 
Iteration: 987763020, states[0] = 20.123186, states[40]= 0.000016
Saving checkpoint... 
Iteration: 998901141, states[0] = -84.061541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010664750, states[0] = -84.583792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1023481389, states[0] = -15.630866, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1036877305, states[0] = -82.476842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050164174, states[0] = -32.246904, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1063486303, states[0] = -19.002997, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1076728714, states[0] = 30.382272, states[40]= 0.117338
Saving checkpoint... 
Iteration: 1088449111, states[0] = 12.541331, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1099660118, states[0] = -84.555148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116585723, states[0] = -84.161761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129539561, states[0] = -75.827546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143339350, states[0] = -84.584546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157388356, states[0] = -84.683813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170361039, states[0] = -84.633109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184187540, states[0] = -50.270355, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1197500793, states[0] = -27.767421, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1209207428, states[0] = -72.406188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222988222, states[0] = -84.514025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236119767, states[0] = 14.411232, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1249056247, states[0] = -84.676579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262192470, states[0] = -51.402070, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1276111974, states[0] = 19.523105, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1289876838, states[0] = -70.756189, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1303561251, states[0] = -83.332058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317245360, states[0] = -84.004058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331276791, states[0] = -84.257723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344564183, states[0] = -83.443212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357944392, states[0] = -84.254390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371628131, states[0] = -84.355456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385741463, states[0] = 30.059366, states[40]= 0.304220
Saving checkpoint... 
Iteration: 1399132114, states[0] = 12.095785, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1412325979, states[0] = -84.490701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1425716134, states[0] = -84.645411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439656653, states[0] = -84.474128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452831527, states[0] = -10.302640, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1466715737, states[0] = -84.639749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478480201, states[0] = 5.672629, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1492164571, states[0] = -7.880988, states[40]= 0.000314
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.556002
 - CaMKt in component CaMK (millimolar): 0.039013
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.834916
 - nass in component intracellular_ions (millimolar): 6.835071
 - ki in component intracellular_ions (millimolar): 144.827452
 - kss in component intracellular_ions (millimolar): 144.827424
 - cansr in component intracellular_ions (millimolar): 2.055082
 - cajsr in component intracellular_ions (millimolar): 1.809375
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010252
 - hf in component INa (dimensionless): 0.572606
 - hs in component INa (dimensionless): 0.572449
 - j in component INa (dimensionless): 0.571593
 - hsp in component INa (dimensionless): 0.325560
 - jp in component INa (dimensionless): 0.570887
 - mL in component INaL (dimensionless): 0.000354
 - hL in component INaL (dimensionless): 0.345691
 - hLp in component INaL (dimensionless): 0.150463
 - a in component Ito (dimensionless): 0.001252
 - iF in component Ito (dimensionless): 0.999202
 - iS in component Ito (dimensionless): 0.365391
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999202
 - iSp in component Ito (dimensionless): 0.399594
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842749
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995735
 - jca in component ICaL (dimensionless): 0.998112
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005907
 - xrf in component IKr (dimensionless): 0.000413
 - xrs in component IKr (dimensionless): 0.674465
 - xs1 in component IKs (dimensionless): 0.386059
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996788
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:38:58 (5158): called boinc_finish(0)

</stderr_txt>
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