𝕏

Task 55622306

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_719_1
Workunit 26412036
Created 1 Jul 2024, 15:41:33 UTC
Sent 2 Jul 2024, 4:20:41 UTC
Report deadline 5 Jul 2024, 4:20:41 UTC
Received 2 Jul 2024, 23:39:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 15 min 7 sec
CPU time 1 hours 3 min
Validate state Valid
Credit 42.04
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.65 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_719.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_719_1_r1265733029_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-TESZT_Block_K1_75-conf_719_1_r1265733029_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 101.867548
     * GNaL_b in INaL: 0.005769
     * Gto_b in Ito: 0.082044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031298
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.041584
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.973407
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032214
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11483770, states[0] = -91.937269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23718633, states[0] = -86.361027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35561795, states[0] = 12.745067, states[40]= 0.003437
Saving checkpoint... 
Iteration: 47258779, states[0] = -89.828445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59468929, states[0] = -91.412227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70719189, states[0] = -85.247087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83670427, states[0] = -68.971515, states[40]= 0.000003
Saving checkpoint... 
Iteration: 96911660, states[0] = -91.254991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109857609, states[0] = -91.072126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122689058, states[0] = -76.536349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134464554, states[0] = -91.313681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145403986, states[0] = -91.209175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157941447, states[0] = -91.278096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171372604, states[0] = -91.110135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183708249, states[0] = -82.401075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195590393, states[0] = -2.579916, states[40]= 0.004041
Saving checkpoint... 
Iteration: 208325275, states[0] = -90.863091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222058337, states[0] = 14.637831, states[40]= 0.003170
Saving checkpoint... 
Iteration: 233789979, states[0] = -90.477834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247021794, states[0] = 27.365701, states[40]= 0.001947
Saving checkpoint... 
Iteration: 259871025, states[0] = -91.099412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272232874, states[0] = -87.270855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285292369, states[0] = -90.515005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297835044, states[0] = -90.926348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311510409, states[0] = 28.249253, states[40]= 0.040620
Saving checkpoint... 
Iteration: 324119007, states[0] = -29.322725, states[40]= 0.000966
Saving checkpoint... 
Iteration: 337335239, states[0] = -90.927250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349871367, states[0] = -91.099845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362717558, states[0] = -84.601016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375602561, states[0] = -13.405703, states[40]= 0.001914
Saving checkpoint... 
Iteration: 388529415, states[0] = 25.383290, states[40]= 0.001432
Saving checkpoint... 
Iteration: 399925658, states[0] = -91.243872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412055164, states[0] = 15.942900, states[40]= 0.002922
Saving checkpoint... 
Iteration: 424909546, states[0] = -91.210897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435182614, states[0] = -74.032684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 447761417, states[0] = -89.671162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461003594, states[0] = 34.402703, states[40]= 0.380430
Saving checkpoint... 
Iteration: 473615631, states[0] = -26.144608, states[40]= 0.001097
Saving checkpoint... 
Iteration: 486384132, states[0] = -91.142632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498941118, states[0] = -91.268931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512177876, states[0] = -72.092158, states[40]= 0.000002
Saving checkpoint... 
Iteration: 524653138, states[0] = -58.678231, states[40]= 0.000018
Saving checkpoint... 
Iteration: 538762811, states[0] = -89.732790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551297500, states[0] = -90.587128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562982481, states[0] = -91.314728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575447550, states[0] = -91.277694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588109581, states[0] = -20.340367, states[40]= 0.001221
Saving checkpoint... 
Iteration: 600581832, states[0] = 3.150673, states[40]= 0.004442
Saving checkpoint... 
Iteration: 611900393, states[0] = -91.188027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624529920, states[0] = 25.228383, states[40]= 0.001441
Saving checkpoint... 
Iteration: 636283434, states[0] = -90.354105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649539678, states[0] = 21.895211, states[40]= 0.001850
Saving checkpoint... 
Iteration: 662090707, states[0] = -2.806961, states[40]= 0.004009
Saving checkpoint... 
Iteration: 674385388, states[0] = -91.145628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686796486, states[0] = -90.572663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699842992, states[0] = -90.970346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712974455, states[0] = -91.307192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725384262, states[0] = -91.141884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738301298, states[0] = -90.634509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751356587, states[0] = -91.037520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764848140, states[0] = -90.997108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775242744, states[0] = -88.402201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787744995, states[0] = -88.608184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801007548, states[0] = 28.512854, states[40]= 0.105816
Saving checkpoint... 
Iteration: 812931294, states[0] = -91.251821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823905950, states[0] = -91.200653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835735081, states[0] = -87.555511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846756044, states[0] = -89.394150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858802230, states[0] = -90.645046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871103055, states[0] = -13.891792, states[40]= 0.001835
Saving checkpoint... 
Iteration: 883100429, states[0] = -11.316402, states[40]= 0.002297
Saving checkpoint... 
Iteration: 895517671, states[0] = 28.036371, states[40]= 0.004367
Saving checkpoint... 
Iteration: 908207889, states[0] = -82.286320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920806369, states[0] = -90.691301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934766103, states[0] = -89.864510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947788086, states[0] = -90.440602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959991438, states[0] = -91.319432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971693498, states[0] = -77.981698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984355620, states[0] = -91.032001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997183232, states[0] = -74.271952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1011282981, states[0] = -90.342743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023257083, states[0] = -89.450795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035503985, states[0] = 33.077147, states[40]= 0.339489
Saving checkpoint... 
Iteration: 1046638988, states[0] = -47.535230, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1059065946, states[0] = 11.340557, states[40]= 0.003743
Saving checkpoint... 
Iteration: 1072409038, states[0] = -91.206630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086331330, states[0] = -90.898669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098343556, states[0] = -90.971458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109834189, states[0] = -90.916868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121345889, states[0] = -90.983769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133677572, states[0] = -71.959234, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1145529716, states[0] = 25.292045, states[40]= 0.001437
Saving checkpoint... 
Iteration: 1157905472, states[0] = -91.197912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170130617, states[0] = -40.040340, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1181201908, states[0] = -80.618379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193252771, states[0] = -89.193543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206142642, states[0] = -50.654441, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1217928840, states[0] = -91.245646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230258176, states[0] = -89.507748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242847821, states[0] = -90.993148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253975806, states[0] = -91.305821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267259814, states[0] = -89.590228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279652594, states[0] = -58.297489, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1292693931, states[0] = -78.123976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304598243, states[0] = -9.230038, states[40]= 0.002734
Saving checkpoint... 
Iteration: 1315599461, states[0] = -10.382874, states[40]= 0.002488
Saving checkpoint... 
Iteration: 1327776238, states[0] = -90.183795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340561853, states[0] = 13.150989, states[40]= 0.003443
Saving checkpoint... 
Iteration: 1352311842, states[0] = -90.744180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364051802, states[0] = 17.287619, states[40]= 0.002662
Saving checkpoint... 
Iteration: 1376191841, states[0] = -77.418365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387997436, states[0] = -91.321256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400655372, states[0] = -60.180138, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1413010667, states[0] = 28.254398, states[40]= 0.037279
Saving checkpoint... 
Iteration: 1425891557, states[0] = -91.160298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437748555, states[0] = -88.895320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450243280, states[0] = -88.448184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461991195, states[0] = -91.316872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472237852, states[0] = -87.884467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484035966, states[0] = 23.223805, states[40]= 0.001659
Saving checkpoint... 
Iteration: 1496199847, states[0] = -80.001616, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.198123
 - CaMKt in component CaMK (millimolar): 0.012386
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.602997
 - nass in component intracellular_ions (millimolar): 6.603090
 - ki in component intracellular_ions (millimolar): 145.284063
 - kss in component intracellular_ions (millimolar): 145.284044
 - cansr in component intracellular_ions (millimolar): 1.638241
 - cajsr in component intracellular_ions (millimolar): 1.595673
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005257
 - hf in component INa (dimensionless): 0.799612
 - hs in component INa (dimensionless): 0.799574
 - j in component INa (dimensionless): 0.799308
 - hsp in component INa (dimensionless): 0.590093
 - jp in component INa (dimensionless): 0.799097
 - mL in component INaL (dimensionless): 0.000100
 - hL in component INaL (dimensionless): 0.586004
 - hLp in component INaL (dimensionless): 0.309080
 - a in component Ito (dimensionless): 0.000800
 - iF in component Ito (dimensionless): 0.999751
 - iS in component Ito (dimensionless): 0.572957
 - ap in component Ito (dimensionless): 0.000408
 - iFp in component Ito (dimensionless): 0.999751
 - iSp in component Ito (dimensionless): 0.627639
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914047
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999826
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002923
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.444575
 - xs1 in component IKs (dimensionless): 0.272616
 - xs2 in component IKs (dimensionless): 0.000133
 - xk1 in component IK1 (dimensionless): 0.998155
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:25:50 (27497): called boinc_finish(0)

</stderr_txt>
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