𝕏

Task 55621504

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719_0
Workunit 26411636
Created 1 Jul 2024, 15:41:12 UTC
Sent 2 Jul 2024, 4:20:41 UTC
Report deadline 5 Jul 2024, 4:20:41 UTC
Received 3 Jul 2024, 2:01:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 14 min 8 sec
CPU time 1 hours 2 min 19 sec
Validate state Valid
Credit 43.60
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 4.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719_0_r756703934_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719_0_r756703934_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.867548
     * GNaL_b in INaL: 0.005769
     * Gto_b in Ito: 0.082044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031298
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.166335
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.973407
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032214
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13046648, states[0] = 19.668956, states[40]= 0.003093
Saving checkpoint... 
Iteration: 26526581, states[0] = -94.736141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39519979, states[0] = -94.710350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52316622, states[0] = -94.558819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65434603, states[0] = -94.660215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77319691, states[0] = -94.550594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89292587, states[0] = -94.499914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102651752, states[0] = -94.696307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116272494, states[0] = -94.450907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128339630, states[0] = -94.569312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141076662, states[0] = 9.929320, states[40]= 0.004281
Saving checkpoint... 
Iteration: 154809545, states[0] = -94.694524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166693549, states[0] = -94.693221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179274087, states[0] = -94.451346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190915250, states[0] = -94.691826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202556197, states[0] = -94.681051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216201226, states[0] = -94.047140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227759063, states[0] = -94.693290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240121956, states[0] = -20.420174, states[40]= 0.001375
Saving checkpoint... 
Iteration: 251631172, states[0] = -94.689042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263534720, states[0] = -94.676769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276266567, states[0] = -94.431575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288999438, states[0] = -94.689081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300489581, states[0] = -94.665488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312434502, states[0] = -94.643649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324156942, states[0] = -50.759694, states[40]= 0.000088
Saving checkpoint... 
Iteration: 337055906, states[0] = 17.956020, states[40]= 0.003025
Saving checkpoint... 
Iteration: 349803179, states[0] = -94.692765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362099259, states[0] = -2.008309, states[40]= 0.004155
Saving checkpoint... 
Iteration: 375191783, states[0] = -91.673756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387604231, states[0] = -94.686406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399219753, states[0] = -94.279436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412221134, states[0] = -94.284818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425334876, states[0] = -94.559754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437146185, states[0] = -40.932893, states[40]= 0.000365
Saving checkpoint... 
Iteration: 449464569, states[0] = -94.656640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462868705, states[0] = -94.691692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476675364, states[0] = -94.690949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489704236, states[0] = -94.691853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502335098, states[0] = -94.559900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516273045, states[0] = -94.447408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528386906, states[0] = -94.612919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540955889, states[0] = -94.689668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553681893, states[0] = -94.691056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565530343, states[0] = -94.675241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579512925, states[0] = -94.671302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591885475, states[0] = -94.691140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603961783, states[0] = -94.689407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616416883, states[0] = -94.633382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629206480, states[0] = -94.195201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640877639, states[0] = -94.691199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653312303, states[0] = -94.526216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666453682, states[0] = -94.651854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679402116, states[0] = -94.623830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691659255, states[0] = -94.689822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704421871, states[0] = -94.636122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716914714, states[0] = -94.690300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727869046, states[0] = -94.691195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740290454, states[0] = -94.485961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753152413, states[0] = -46.549061, states[40]= 0.000166
Saving checkpoint... 
Iteration: 766491915, states[0] = -94.665294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779613752, states[0] = -94.686561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792835344, states[0] = -94.691600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805326763, states[0] = -94.547994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817544809, states[0] = -94.677564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830401757, states[0] = -94.623303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843679967, states[0] = -94.690448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856822936, states[0] = -94.691633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871239926, states[0] = -94.351352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883521287, states[0] = -94.672698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896021988, states[0] = 26.855605, states[40]= 0.002217
Saving checkpoint... 
Iteration: 906898697, states[0] = -94.690291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920591679, states[0] = -94.684102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933853219, states[0] = -94.691079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946990121, states[0] = -94.688059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959519349, states[0] = -94.672117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971544614, states[0] = -94.677244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983757561, states[0] = -94.691671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996768994, states[0] = -94.691676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009550639, states[0] = -94.678227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021784167, states[0] = -94.691613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034432353, states[0] = -94.641189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047193017, states[0] = -92.379239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058892803, states[0] = -94.690130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069770576, states[0] = -94.691542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082900617, states[0] = -94.689925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095549009, states[0] = -94.677788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109029031, states[0] = 25.662885, states[40]= 0.001684
Saving checkpoint... 
Iteration: 1121502798, states[0] = -94.667708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132947529, states[0] = -94.688774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144644923, states[0] = -94.688187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156153036, states[0] = -47.121666, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1167675415, states[0] = -94.689671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180217840, states[0] = -94.270238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193353770, states[0] = -94.580873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205600477, states[0] = -94.684514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218646998, states[0] = -94.688175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232140604, states[0] = -36.080265, states[40]= 0.000671
Saving checkpoint... 
Iteration: 1244456401, states[0] = -94.651918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257127692, states[0] = -25.227072, states[40]= 0.001414
Saving checkpoint... 
Iteration: 1269862464, states[0] = -94.690306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281960519, states[0] = -94.688182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293955811, states[0] = -94.688275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306342521, states[0] = -94.567744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318313264, states[0] = -94.526543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329106296, states[0] = -7.100679, states[40]= 0.003177
Saving checkpoint... 
Iteration: 1341912788, states[0] = -94.689185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354277078, states[0] = -94.455489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367764481, states[0] = -94.690982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380146150, states[0] = -40.899925, states[40]= 0.000366
Saving checkpoint... 
Iteration: 1392664403, states[0] = -94.688775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405067609, states[0] = 13.715658, states[40]= 0.003802
Saving checkpoint... 
Iteration: 1417864062, states[0] = -94.690004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430871145, states[0] = -94.689856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442834103, states[0] = -94.690413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456282652, states[0] = -94.468004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467731137, states[0] = -94.690548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479483620, states[0] = -94.661412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491588769, states[0] = -94.682714, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.562719
 - CaMKt in component CaMK (millimolar): 0.004221
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.484834
 - nass in component intracellular_ions (millimolar): 6.484920
 - ki in component intracellular_ions (millimolar): 145.426858
 - kss in component intracellular_ions (millimolar): 145.426843
 - cansr in component intracellular_ions (millimolar): 1.592115
 - cajsr in component intracellular_ions (millimolar): 1.591395
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003745
 - hf in component INa (dimensionless): 0.873990
 - hs in component INa (dimensionless): 0.873991
 - j in component INa (dimensionless): 0.873996
 - hsp in component INa (dimensionless): 0.714635
 - jp in component INa (dimensionless): 0.873999
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719983
 - hLp in component INaL (dimensionless): 0.511923
 - a in component Ito (dimensionless): 0.000638
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.891628
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.931469
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975186
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002724
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.098214
 - xs1 in component IKs (dimensionless): 0.126148
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997425
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:56:32 (28319): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719_0_r756703934_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Coppini_2000-conf_719_0_r756703934_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.867548
     * GNaL_b in INaL: 0.005769
     * Gto_b in Ito: 0.082044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031298
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.166335
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.973407
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032214
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1491588769
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.682714 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.562719
 - CaMKt in component CaMK (millimolar): 0.004221
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.484834
 - nass in component intracellular_ions (millimolar): 6.484920
 - ki in component intracellular_ions (millimolar): 145.426858
 - kss in component intracellular_ions (millimolar): 145.426843
 - cansr in component intracellular_ions (millimolar): 1.592115
 - cajsr in component intracellular_ions (millimolar): 1.591395
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003745
 - hf in component INa (dimensionless): 0.873990
 - hs in component INa (dimensionless): 0.873991
 - j in component INa (dimensionless): 0.873996
 - hsp in component INa (dimensionless): 0.714635
 - jp in component INa (dimensionless): 0.873999
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719983
 - hLp in component INaL (dimensionless): 0.511923
 - a in component Ito (dimensionless): 0.000638
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.891628
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.931469
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975186
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002724
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.098214
 - xs1 in component IKs (dimensionless): 0.126148
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997425
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:00:19 (29330): called boinc_finish(0)

</stderr_txt>
]]>