𝕏

Task 55616742

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_814_1
Workunit 26409257
Created 1 Jul 2024, 15:39:00 UTC
Sent 2 Jul 2024, 3:30:35 UTC
Report deadline 5 Jul 2024, 13:06:35 UTC
Received 5 Jul 2024, 2:32:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219798
Run time 2 hours 53 min 8 sec
CPU time 2 hours 48 min 31 sec
Validate state Valid
Credit 62.59
Device peak FLOPS 2.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 6.39 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_814.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_814_1_r1989322557_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_814_1_r1989322557_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.738461
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.086126
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032174
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.162895
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.651265
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030025
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13207689, states[0] = -94.931844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26752853, states[0] = -94.963764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39426035, states[0] = -95.049821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52878970, states[0] = -95.024424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66443711, states[0] = -95.034836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79927561, states[0] = -95.026515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91784807, states[0] = -94.952888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105337040, states[0] = -94.988100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118926401, states[0] = -95.019603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132482919, states[0] = -95.028957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146066150, states[0] = 4.998377, states[40]= 0.004717
Saving checkpoint... 
Iteration: 159653031, states[0] = -77.212489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173013977, states[0] = 22.226061, states[40]= 0.022188
Saving checkpoint... 
Iteration: 186574835, states[0] = 0.655305, states[40]= 0.004335
Saving checkpoint... 
Iteration: 200165017, states[0] = -93.089062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213738696, states[0] = -94.891802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226572213, states[0] = 2.066361, states[40]= 0.004489
Saving checkpoint... 
Iteration: 240151028, states[0] = -73.893356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253726484, states[0] = -94.872486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266946434, states[0] = -95.020832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279576943, states[0] = -0.530914, states[40]= 0.004181
Saving checkpoint... 
Iteration: 293074554, states[0] = 0.821262, states[40]= 0.004355
Saving checkpoint... 
Iteration: 306605883, states[0] = -24.641121, states[40]= 0.000730
Saving checkpoint... 
Iteration: 319972465, states[0] = -95.025289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332950606, states[0] = -95.021556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346475094, states[0] = -95.025666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359781854, states[0] = -94.943102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373365041, states[0] = -94.996856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386942982, states[0] = -95.020028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400483373, states[0] = -95.026818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413365202, states[0] = -94.996896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426500198, states[0] = -70.700474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440039392, states[0] = 15.699336, states[40]= 0.005241
Saving checkpoint... 
Iteration: 452508470, states[0] = 23.694215, states[40]= 0.076279
Saving checkpoint... 
Iteration: 465882988, states[0] = -95.003718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479427528, states[0] = -95.016605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492998953, states[0] = -95.028758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506568973, states[0] = 3.693967, states[40]= 0.004629
Saving checkpoint... 
Iteration: 520120319, states[0] = -38.437530, states[40]= 0.000166
Saving checkpoint... 
Iteration: 533697849, states[0] = -94.818253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547088132, states[0] = -8.338849, states[40]= 0.002686
Saving checkpoint... 
Iteration: 560313921, states[0] = -94.969012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573860777, states[0] = -94.994895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587421905, states[0] = -95.015185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600262938, states[0] = -94.923097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613755057, states[0] = -94.913617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627301701, states[0] = -94.960017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639568089, states[0] = 4.119412, states[40]= 0.004660
Saving checkpoint... 
Iteration: 653071543, states[0] = 2.414796, states[40]= 0.004522
Saving checkpoint... 
Iteration: 666574058, states[0] = 1.092193, states[40]= 0.004386
Saving checkpoint... 
Iteration: 680104080, states[0] = -22.941685, states[40]= 0.000810
Saving checkpoint... 
Iteration: 693680833, states[0] = -94.769294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707231480, states[0] = -94.880239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720788278, states[0] = -94.948772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734115394, states[0] = -33.658618, states[40]= 0.000314
Saving checkpoint... 
Iteration: 747712199, states[0] = -94.846726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761291247, states[0] = -94.951351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774503080, states[0] = 36.565945, states[40]= 0.141705
Saving checkpoint... 
Iteration: 787638680, states[0] = -57.956417, states[40]= 0.000008
Saving checkpoint... 
Iteration: 801211590, states[0] = -94.845537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814777824, states[0] = -94.938885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827013054, states[0] = 22.377625, states[40]= 0.026695
Saving checkpoint... 
Iteration: 840568286, states[0] = 4.025263, states[40]= 0.004653
Saving checkpoint... 
Iteration: 854130649, states[0] = -49.089991, states[40]= 0.000033
Saving checkpoint... 
Iteration: 867708664, states[0] = -94.839876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881235558, states[0] = -94.886462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894802224, states[0] = -94.960245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908287312, states[0] = -94.947783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921828853, states[0] = -94.978336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935378579, states[0] = -95.001813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948936376, states[0] = -95.018277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961793272, states[0] = -94.952950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975292643, states[0] = -94.952407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988618722, states[0] = -36.872730, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1002085688, states[0] = -6.393282, states[40]= 0.003105
Saving checkpoint... 
Iteration: 1013922985, states[0] = -95.015166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027416029, states[0] = -95.013407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040865279, states[0] = -94.996511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054367984, states[0] = -94.997620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067478366, states[0] = -95.025666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081027101, states[0] = 19.578946, states[40]= 0.006494
Saving checkpoint... 
Iteration: 1094328559, states[0] = -94.978046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107877950, states[0] = -95.001465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121275838, states[0] = -94.936693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134399013, states[0] = -95.008543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147111965, states[0] = -30.388303, states[40]= 0.000457
Saving checkpoint... 
Iteration: 1160417427, states[0] = -95.013680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173975905, states[0] = -95.025234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187536754, states[0] = 16.611857, states[40]= 0.005382
Saving checkpoint... 
Iteration: 1199806425, states[0] = -94.963226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213367303, states[0] = -94.997236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226919722, states[0] = -95.014218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240524640, states[0] = 20.210709, states[40]= 0.007117
Saving checkpoint... 
Iteration: 1254118595, states[0] = -36.748864, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1267675466, states[0] = -94.702413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281086431, states[0] = -6.970078, states[40]= 0.002982
Saving checkpoint... 
Iteration: 1294360920, states[0] = -94.994479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307941894, states[0] = -95.019195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321519650, states[0] = 21.294384, states[40]= 0.009881
Saving checkpoint... 
Iteration: 1334383430, states[0] = -95.003298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347927808, states[0] = -95.016094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359314976, states[0] = -94.969204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369709905, states[0] = -94.841939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380871432, states[0] = -94.998788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390744921, states[0] = -94.899740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404310494, states[0] = -94.966049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417851641, states[0] = -94.990163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431400421, states[0] = -95.008772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444850284, states[0] = -94.989494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458339936, states[0] = -94.984227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471909564, states[0] = -95.011380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485484263, states[0] = -95.026221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499043186, states[0] = 14.334721, states[40]= 0.005100
Saving checkpoint... 
Iteration: 1512265847, states[0] = -95.235559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525169713, states[0] = -95.253150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538642168, states[0] = -95.235836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552129509, states[0] = -95.227221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564286730, states[0] = -22.726549, states[40]= 0.000850
Saving checkpoint... 
Iteration: 1577771399, states[0] = -6.822072, states[40]= 0.003403
Saving checkpoint... 
Iteration: 1591301179, states[0] = -38.820808, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1604371245, states[0] = -95.285210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617832806, states[0] = -95.244432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631268470, states[0] = -95.120583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644699713, states[0] = -37.371358, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1658166268, states[0] = -2.682412, states[40]= 0.004333
Saving checkpoint... 
Iteration: 1671655704, states[0] = 4.371501, states[40]= 0.005321
Saving checkpoint... 
Iteration: 1685111352, states[0] = 23.283220, states[40]= 0.039880
Saving checkpoint... 
Iteration: 1698245797, states[0] = -95.262043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711372793, states[0] = -95.132873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724778919, states[0] = -14.700073, states[40]= 0.001707
Saving checkpoint... 
Iteration: 1738270941, states[0] = -6.638281, states[40]= 0.003450
Saving checkpoint... 
Iteration: 1750395500, states[0] = -95.184426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763867212, states[0] = -95.118103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777162789, states[0] = -95.279946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790618149, states[0] = -95.224775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804074424, states[0] = -1.096514, states[40]= 0.004242
Saving checkpoint... 
Iteration: 1817324099, states[0] = -95.016434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830812546, states[0] = -94.995966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844290939, states[0] = -94.969796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857767331, states[0] = -94.940284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870861606, states[0] = -95.003118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883629657, states[0] = -48.453261, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1897111847, states[0] = -30.514550, states[40]= 0.000451
Saving checkpoint... 
Iteration: 1910550412, states[0] = 11.566436, states[40]= 0.004958
Saving checkpoint... 
Iteration: 1924035442, states[0] = 17.028581, states[40]= 0.005469
Saving checkpoint... 
Iteration: 1936275323, states[0] = -94.936848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949723142, states[0] = -94.866458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963187148, states[0] = -94.793413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976688862, states[0] = -94.797614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990147454, states[0] = -68.723502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2003452528, states[0] = -95.020917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016645903, states[0] = -66.649350, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2030108450, states[0] = -27.064881, states[40]= 0.000617
Saving checkpoint... 
Iteration: 2043578085, states[0] = -1.209578, states[40]= 0.004081
Saving checkpoint... 
Iteration: 2057077341, states[0] = -0.764491, states[40]= 0.004147
Saving checkpoint... 
Iteration: 2069904900, states[0] = -95.009633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083386104, states[0] = -95.003690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096887533, states[0] = -95.004164, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903644
 - CaMKt in component CaMK (millimolar): 0.007084
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.582282
 - nass in component intracellular_ions (millimolar): 6.582343
 - ki in component intracellular_ions (millimolar): 145.393487
 - kss in component intracellular_ions (millimolar): 145.393467
 - cansr in component intracellular_ions (millimolar): 1.319146
 - cajsr in component intracellular_ions (millimolar): 1.281004
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880032
 - hs in component INa (dimensionless): 0.880027
 - j in component INa (dimensionless): 0.879998
 - hsp in component INa (dimensionless): 0.725888
 - jp in component INa (dimensionless): 0.879978
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709873
 - hLp in component INaL (dimensionless): 0.451788
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620835
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695622
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934929
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001631
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331897
 - xs1 in component IKs (dimensionless): 0.242417
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:32:15 (11280): called boinc_finish(0)

</stderr_txt>
]]>


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