𝕏

Task 55616481

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0
Workunit 26409127
Created 1 Jul 2024, 15:38:54 UTC
Sent 2 Jul 2024, 3:28:31 UTC
Report deadline 5 Jul 2024, 3:28:31 UTC
Received 5 Jul 2024, 7:34:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228256
Run time 1 hours 9 min 56 sec
CPU time 40 min 11 sec
Validate state Valid
Credit 45.89
Device peak FLOPS 5.64 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.75 MB
Peak swap size 5.39 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0_r1040586937_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0_r1040586937_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.738461
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.086126
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032174
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.162895
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.651265
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030025
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5736375, states[0] = -94.383431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17705983, states[0] = -93.645151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29400384, states[0] = -94.222091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42409080, states[0] = -94.198039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56003576, states[0] = -94.223505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64916121, states[0] = -94.194298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79478218, states[0] = -94.202136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95607047, states[0] = -94.240460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110292576, states[0] = -93.984661, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0_r1040586937_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0_r1040586937_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.738461
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.086126
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032174
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.162895
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.651265
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030025
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 110292576
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.984661 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 117963756, states[0] = -94.214832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132197074, states[0] = -94.208038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146179809, states[0] = -94.230400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158953441, states[0] = -94.222555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167844413, states[0] = -94.108735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184391256, states[0] = -94.214298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199398169, states[0] = -94.214342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214195764, states[0] = -94.217913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227241418, states[0] = -94.209985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241448145, states[0] = -94.223468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253358804, states[0] = -94.244908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268144045, states[0] = -94.249257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282542443, states[0] = 26.180252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294152638, states[0] = -94.218336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307870177, states[0] = -94.146057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315815225, states[0] = -94.246152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324039729, states[0] = -94.220547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337635113, states[0] = -27.202944, states[40]= 0.000457
Saving checkpoint... 
Iteration: 352653609, states[0] = -48.059292, states[40]= 0.000132
Saving checkpoint... 
Iteration: 367610415, states[0] = -2.607367, states[40]= 0.000246
Saving checkpoint... 
Iteration: 383779994, states[0] = -94.227136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397434647, states[0] = -94.206742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413750313, states[0] = -94.227813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426445458, states[0] = -94.221898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437709729, states[0] = -93.559978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448764330, states[0] = -94.227005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459531112, states[0] = -94.210454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472352922, states[0] = -94.206730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486007198, states[0] = -94.236356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501664222, states[0] = -94.216091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512519696, states[0] = 24.438620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528141710, states[0] = -94.246720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542326911, states[0] = -94.206284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554825352, states[0] = -94.206175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566062198, states[0] = -94.233276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577245468, states[0] = -94.206755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592194802, states[0] = -94.207154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602552158, states[0] = 24.670118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618170883, states[0] = -94.246314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628726169, states[0] = -94.226507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642079369, states[0] = -94.208026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657262290, states[0] = -94.205791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672351341, states[0] = -94.204769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682522415, states[0] = 25.080576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698708624, states[0] = -94.226422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710077347, states[0] = 16.253406, states[40]= 0.000008
Saving checkpoint... 
Iteration: 721295507, states[0] = -94.223310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734475530, states[0] = -94.208497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747850341, states[0] = -94.113971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765290865, states[0] = -93.979356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780180242, states[0] = -83.017997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 792857951, states[0] = -94.124922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801860889, states[0] = -94.209563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813823738, states[0] = -94.221521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829878876, states[0] = -94.202956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844014459, states[0] = -94.216030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856675621, states[0] = -94.212355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868171429, states[0] = -94.243854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879513772, states[0] = -94.206536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889501128, states[0] = -94.206610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903935898, states[0] = -94.217435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916318463, states[0] = -94.220673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929419662, states[0] = -94.207388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944719945, states[0] = -94.203394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961427599, states[0] = -94.217088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977549142, states[0] = 25.264397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988507084, states[0] = -94.231405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998925009, states[0] = -94.216788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008957003, states[0] = -94.215842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023838544, states[0] = -94.219002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037824295, states[0] = -94.063524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047316154, states[0] = -94.201397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058361585, states[0] = -94.236993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069367281, states[0] = -94.206821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082487711, states[0] = -94.199531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087626126, states[0] = -17.720844, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1104267644, states[0] = -94.208166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118547540, states[0] = -94.228431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133090440, states[0] = -94.238072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147620684, states[0] = -12.003094, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1156690249, states[0] = -94.209101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164178560, states[0] = -94.209258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178194509, states[0] = -94.240792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193056307, states[0] = -94.233767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208790306, states[0] = -94.218664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214466343, states[0] = -94.203885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226197670, states[0] = -94.221601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238675522, states[0] = -94.222272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252708083, states[0] = -93.538499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265290918, states[0] = -93.974516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280545666, states[0] = -94.231321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291707772, states[0] = -94.207426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306496893, states[0] = -94.211893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313122963, states[0] = -94.238324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328632240, states[0] = -94.222996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338543387, states[0] = -94.226432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354237971, states[0] = -94.206238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363305275, states[0] = -94.236226, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0_r1040586937_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_5000-conf_814_0_r1040586937_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.738461
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.086126
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032174
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.162895
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.651265
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030025
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1363305275
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.236226 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1381367792, states[0] = -94.214611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394001441, states[0] = -94.210916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405947209, states[0] = -94.229868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422595000, states[0] = 7.468968, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1436842404, states[0] = -94.203590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452054167, states[0] = -94.200339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467121627, states[0] = -94.199348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484633071, states[0] = -94.199037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499829101, states[0] = -94.196794, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.071275
 - CaMKt in component CaMK (millimolar): 0.001720
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.096132
 - nass in component intracellular_ions (millimolar): 7.096269
 - ki in component intracellular_ions (millimolar): 144.596951
 - kss in component intracellular_ions (millimolar): 144.596938
 - cansr in component intracellular_ions (millimolar): 2.412248
 - cajsr in component intracellular_ions (millimolar): 2.412609
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003935
 - hf in component INa (dimensionless): 0.864824
 - hs in component INa (dimensionless): 0.864824
 - j in component INa (dimensionless): 0.864826
 - hsp in component INa (dimensionless): 0.697881
 - jp in component INa (dimensionless): 0.864827
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706732
 - hLp in component INaL (dimensionless): 0.512870
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998806
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005450
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001782
 - xs1 in component IKs (dimensionless): 0.023458
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997547
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:34:01 (19276): called boinc_finish(0)

</stderr_txt>
]]>


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