𝕏

Task 55614798

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_812_0
Workunit 26408287
Created 1 Jul 2024, 15:38:12 UTC
Sent 2 Jul 2024, 3:16:48 UTC
Report deadline 5 Jul 2024, 3:16:52 UTC
Received 3 Jul 2024, 15:49:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 39 sec
CPU time 1 hours 29 min 52 sec
Validate state Valid
Credit 46.46
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.84 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_812.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_812_0_r1934118421_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_812_0_r1934118421_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.170388
     * GNaL_b in INaL: 0.006108
     * Gto_b in Ito: 0.087843
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031930
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.162292
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.475896
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034713
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8152284, states[0] = -80.841256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16637928, states[0] = -84.686342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24741330, states[0] = 5.435964, states[40]= 0.000206
Saving checkpoint... 
Iteration: 33098781, states[0] = -15.701965, states[40]= 0.000252
Saving checkpoint... 
Iteration: 41647237, states[0] = -84.689173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50221512, states[0] = -84.363310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58263699, states[0] = -84.557835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66576855, states[0] = -84.475192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74377682, states[0] = 23.147494, states[40]= 0.000010
Saving checkpoint... 
Iteration: 82241739, states[0] = -84.463831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90487272, states[0] = -75.911547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99084498, states[0] = 1.202476, states[40]= 0.000256
Saving checkpoint... 
Iteration: 106354600, states[0] = 31.506200, states[40]= 0.007449
Saving checkpoint... 
Iteration: 114468764, states[0] = -51.868582, states[40]= 0.000024
Saving checkpoint... 
Iteration: 122842307, states[0] = -83.898677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130611108, states[0] = -84.592676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 139589379, states[0] = -84.513542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148307530, states[0] = -84.666826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158494741, states[0] = -79.976851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166601783, states[0] = -84.555177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175837686, states[0] = -83.408303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184551988, states[0] = -84.302319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192757338, states[0] = 0.084167, states[40]= 0.000279
Saving checkpoint... 
Iteration: 200791284, states[0] = -35.389233, states[40]= 0.000140
Saving checkpoint... 
Iteration: 208810512, states[0] = -56.041968, states[40]= 0.000014
Saving checkpoint... 
Iteration: 216562002, states[0] = -84.355174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224158470, states[0] = -73.280931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231790453, states[0] = -32.803822, states[40]= 0.000165
Saving checkpoint... 
Iteration: 240350887, states[0] = 29.749575, states[40]= 0.300651
Saving checkpoint... 
Iteration: 248782078, states[0] = -22.606575, states[40]= 0.000198
Saving checkpoint... 
Iteration: 257156236, states[0] = -68.198777, states[40]= 0.000003
Saving checkpoint... 
Iteration: 265988724, states[0] = -84.681950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275037207, states[0] = 30.087980, states[40]= 0.000521
Saving checkpoint... 
Iteration: 283287003, states[0] = -84.594423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292630355, states[0] = -84.621315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 300460182, states[0] = -32.399333, states[40]= 0.000169
Saving checkpoint... 
Iteration: 309318769, states[0] = -84.670138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317398567, states[0] = 18.882990, states[40]= 0.000022
Saving checkpoint... 
Iteration: 326190917, states[0] = -83.997610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335256840, states[0] = -84.470390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343557508, states[0] = -84.282248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350869785, states[0] = -84.114435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358782413, states[0] = -16.680039, states[40]= 0.000228
Saving checkpoint... 
Iteration: 366566958, states[0] = -84.336266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374527722, states[0] = -84.011266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383190014, states[0] = -83.927975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392310824, states[0] = -84.641344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400512501, states[0] = -82.795665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408875243, states[0] = -84.135439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418216123, states[0] = -84.193473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426479930, states[0] = -46.981918, states[40]= 0.000044
Saving checkpoint... 
Iteration: 435558898, states[0] = -84.257518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442884268, states[0] = -84.194470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450755022, states[0] = 9.985692, states[40]= 0.000096
Saving checkpoint... 
Iteration: 458796550, states[0] = -27.035567, states[40]= 0.000197
Saving checkpoint... 
Iteration: 467298629, states[0] = -84.597434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476155490, states[0] = -54.072837, states[40]= 0.000018
Saving checkpoint... 
Iteration: 484428360, states[0] = 7.005051, states[40]= 0.000141
Saving checkpoint... 
Iteration: 492180730, states[0] = -81.647347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499731034, states[0] = 23.722203, states[40]= 0.000010
Saving checkpoint... 
Iteration: 507443440, states[0] = -2.902131, states[40]= 0.000323
Saving checkpoint... 
Iteration: 516029948, states[0] = 30.879379, states[40]= 0.487681
Saving checkpoint... 
Iteration: 523919859, states[0] = -84.400952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533581546, states[0] = -84.370152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541783923, states[0] = -8.082586, states[40]= 0.000330
Saving checkpoint... 
Iteration: 549327148, states[0] = -84.657136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557066279, states[0] = 24.163894, states[40]= 0.000010
Saving checkpoint... 
Iteration: 565819562, states[0] = -46.248636, states[40]= 0.000048
Saving checkpoint... 
Iteration: 573835086, states[0] = -63.523256, states[40]= 0.000005
Saving checkpoint... 
Iteration: 582783443, states[0] = -5.542985, states[40]= 0.000338
Saving checkpoint... 
Iteration: 590869585, states[0] = -83.972805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599871738, states[0] = -83.998254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607983795, states[0] = -84.625602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615630289, states[0] = -84.565935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622980821, states[0] = -84.615613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632218887, states[0] = -84.122832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641423967, states[0] = 14.062424, states[40]= 0.000051
Saving checkpoint... 
Iteration: 649214167, states[0] = -84.071978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657053673, states[0] = 30.794878, states[40]= 0.001322
Saving checkpoint... 
Iteration: 665997727, states[0] = -84.650442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673268708, states[0] = -84.439096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680890734, states[0] = -84.145398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688838631, states[0] = -60.832263, states[40]= 0.000007
Saving checkpoint... 
Iteration: 696713334, states[0] = 31.199507, states[40]= 0.032258
Saving checkpoint... 
Iteration: 705006282, states[0] = -84.663445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713209256, states[0] = -83.973219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722046667, states[0] = 30.890809, states[40]= 0.050666
Saving checkpoint... 
Iteration: 730238449, states[0] = -84.237325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739067192, states[0] = 27.691911, states[40]= 0.000050
Saving checkpoint... 
Iteration: 746892379, states[0] = -84.129619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754604963, states[0] = -84.431475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 762849332, states[0] = -69.662820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 772543657, states[0] = -83.937296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780560759, states[0] = -84.128852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789288169, states[0] = -84.497762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798447161, states[0] = 5.052966, states[40]= 0.000179
Saving checkpoint... 
Iteration: 807378853, states[0] = 29.908275, states[40]= 0.343639
Saving checkpoint... 
Iteration: 815472807, states[0] = -17.698634, states[40]= 0.000217
Saving checkpoint... 
Iteration: 823506684, states[0] = -54.620113, states[40]= 0.000017
Saving checkpoint... 
Iteration: 831854757, states[0] = -72.249374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840468408, states[0] = -11.204543, states[40]= 0.000295
Saving checkpoint... 
Iteration: 848681899, states[0] = -84.663824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856625109, states[0] = -84.497201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864715453, states[0] = 29.744712, states[40]= 0.298866
Saving checkpoint... 
Iteration: 873405246, states[0] = 28.465319, states[40]= 0.000098
Saving checkpoint... 
Iteration: 881471916, states[0] = -12.855142, states[40]= 0.000275
Saving checkpoint... 
Iteration: 889641735, states[0] = -84.552278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897368866, states[0] = -84.694617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905448419, states[0] = 7.617154, states[40]= 0.000131
Saving checkpoint... 
Iteration: 913789425, states[0] = 2.951878, states[40]= 0.000220
Saving checkpoint... 
Iteration: 922464718, states[0] = -3.352016, states[40]= 0.000328
Saving checkpoint... 
Iteration: 931034829, states[0] = -84.690076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938799537, states[0] = -3.946223, states[40]= 0.000330
Saving checkpoint... 
Iteration: 947239471, states[0] = -84.156073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955077013, states[0] = 28.077981, states[40]= 0.000070
Saving checkpoint... 
Iteration: 964210828, states[0] = -83.435323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971871576, states[0] = -81.720112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980414734, states[0] = 26.821946, states[40]= 0.000026
Saving checkpoint... 
Iteration: 988295115, states[0] = -84.480677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 995825701, states[0] = -29.552928, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1003535207, states[0] = -78.355930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011664419, states[0] = -84.600131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018843978, states[0] = -48.156259, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1026984312, states[0] = -84.557123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035376332, states[0] = -84.692505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1043588985, states[0] = -84.241390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051633082, states[0] = -84.485338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1061323760, states[0] = -84.570476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070652227, states[0] = -84.553106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079060789, states[0] = 29.729862, states[40]= 0.190323
Saving checkpoint... 
Iteration: 1086700390, states[0] = -84.671140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094856133, states[0] = -57.514914, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1103367072, states[0] = -84.669267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111494892, states[0] = -25.951743, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1120123876, states[0] = 8.787070, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1128497302, states[0] = -27.678278, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1136185076, states[0] = -50.250220, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1145294622, states[0] = -84.439464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1153433124, states[0] = 22.445414, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1161704585, states[0] = -84.670357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170385684, states[0] = -84.693603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179966486, states[0] = -84.454927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188700341, states[0] = -84.659131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196499870, states[0] = -26.758781, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1203422279, states[0] = 28.268025, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1211596126, states[0] = -84.228500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219038300, states[0] = -84.664507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227712779, states[0] = -84.677512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236053334, states[0] = -84.688557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243971156, states[0] = -84.460170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1251522149, states[0] = -48.012881, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1259297821, states[0] = -84.424800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1267385785, states[0] = -84.684000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274855549, states[0] = -46.807520, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1282181577, states[0] = -38.485550, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1290532937, states[0] = -57.924100, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1299904798, states[0] = -83.951846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308781331, states[0] = 18.959992, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1317278153, states[0] = -84.295702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324914357, states[0] = -84.053710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332663805, states[0] = -84.542056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340169965, states[0] = -22.556037, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1348607566, states[0] = -84.257837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357451370, states[0] = 18.487695, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1365463193, states[0] = 12.401920, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1373939657, states[0] = -84.239745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382455415, states[0] = 17.049334, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1390422236, states[0] = 31.102690, states[40]= 0.002198
Saving checkpoint... 
Iteration: 1398479761, states[0] = 3.343040, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1406718513, states[0] = -84.667843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414989177, states[0] = -84.495946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422846131, states[0] = -28.526122, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1430422996, states[0] = 31.307691, states[40]= 0.003412
Saving checkpoint... 
Iteration: 1438144479, states[0] = 5.912630, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1447672322, states[0] = -84.548667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455699398, states[0] = -84.622537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463763381, states[0] = 30.076733, states[40]= 0.000508
Saving checkpoint... 
Iteration: 1472137565, states[0] = 11.066493, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1480835453, states[0] = -13.105796, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1489768153, states[0] = 28.927851, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1498623974, states[0] = -84.313119, states[40]= 0.000000
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.571168
 - CaMKt in component CaMK (millimolar): 0.038785
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.797198
 - nass in component intracellular_ions (millimolar): 6.797353
 - ki in component intracellular_ions (millimolar): 144.868241
 - kss in component intracellular_ions (millimolar): 144.868212
 - cansr in component intracellular_ions (millimolar): 2.050688
 - cajsr in component intracellular_ions (millimolar): 1.806223
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010237
 - hf in component INa (dimensionless): 0.573216
 - hs in component INa (dimensionless): 0.573062
 - j in component INa (dimensionless): 0.572225
 - hsp in component INa (dimensionless): 0.326117
 - jp in component INa (dimensionless): 0.571533
 - mL in component INaL (dimensionless): 0.000353
 - hL in component INaL (dimensionless): 0.346469
 - hLp in component INaL (dimensionless): 0.151011
 - a in component Ito (dimensionless): 0.001251
 - iF in component Ito (dimensionless): 0.999204
 - iS in component Ito (dimensionless): 0.365664
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999204
 - iSp in component Ito (dimensionless): 0.400044
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842897
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995752
 - jca in component ICaL (dimensionless): 0.998110
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005877
 - xrf in component IKr (dimensionless): 0.000407
 - xrs in component IKr (dimensionless): 0.673410
 - xs1 in component IKs (dimensionless): 0.386061
 - xs2 in component IKs (dimensionless): 0.000280
 - xk1 in component IK1 (dimensionless): 0.996784
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
16:07:29 (58432): called boinc_finish(0)

</stderr_txt>
]]>


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