𝕏

Task 55614793

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_512_1
Workunit 26408284
Created 1 Jul 2024, 15:38:12 UTC
Sent 2 Jul 2024, 3:16:05 UTC
Report deadline 5 Jul 2024, 3:16:09 UTC
Received 2 Jul 2024, 19:42:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 16 min 35 sec
CPU time 1 hours 3 min 16 sec
Validate state Valid
Credit 43.60
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.72 MB
Peak swap size 4.10 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_512.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_512_1_r1717092516_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_666-conf_512_1_r1717092516_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.664279
     * GNaL_b in INaL: 0.006225
     * Gto_b in Ito: 0.081410
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032009
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.162047
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.994830
     * GKb_b in IKb: 0.003793
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034043
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12193811, states[0] = -84.225508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24264106, states[0] = -84.534410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36956732, states[0] = -84.605166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49567446, states[0] = -84.400344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61022845, states[0] = 31.254647, states[40]= 0.001895
Saving checkpoint... 
Iteration: 72912853, states[0] = -84.453542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84860171, states[0] = -84.119825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97024474, states[0] = 31.282334, states[40]= 0.002014
Saving checkpoint... 
Iteration: 108941601, states[0] = -84.554928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122064153, states[0] = 14.349207, states[40]= 0.000050
Saving checkpoint... 
Iteration: 134605072, states[0] = -84.540038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146479672, states[0] = -62.436538, states[40]= 0.000006
Saving checkpoint... 
Iteration: 158047421, states[0] = 23.720867, states[40]= 0.000010
Saving checkpoint... 
Iteration: 169607359, states[0] = -84.541327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181598210, states[0] = -84.506655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193535853, states[0] = -84.147875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206129149, states[0] = -39.899760, states[40]= 0.000095
Saving checkpoint... 
Iteration: 217986155, states[0] = -84.650199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231520094, states[0] = -83.975543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242492318, states[0] = -72.479773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254064981, states[0] = 17.412320, states[40]= 0.000029
Saving checkpoint... 
Iteration: 266062424, states[0] = 19.034459, states[40]= 0.000022
Saving checkpoint... 
Iteration: 277706145, states[0] = 29.569257, states[40]= 0.000245
Saving checkpoint... 
Iteration: 289589406, states[0] = -84.445843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301283679, states[0] = -84.548326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313417423, states[0] = 8.453878, states[40]= 0.000119
Saving checkpoint... 
Iteration: 326062598, states[0] = 20.451909, states[40]= 0.000016
Saving checkpoint... 
Iteration: 339225633, states[0] = -84.261689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350992827, states[0] = -84.647322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363204864, states[0] = -84.092533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375962456, states[0] = -84.571966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387364998, states[0] = 31.659225, states[40]= 0.027226
Saving checkpoint... 
Iteration: 399061827, states[0] = 22.605579, states[40]= 0.000011
Saving checkpoint... 
Iteration: 413503407, states[0] = -75.633443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426485522, states[0] = -53.002489, states[40]= 0.000021
Saving checkpoint... 
Iteration: 437188519, states[0] = -83.738614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448743676, states[0] = 16.212056, states[40]= 0.000036
Saving checkpoint... 
Iteration: 460837230, states[0] = -73.313223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470630398, states[0] = -84.559783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482720890, states[0] = 27.871942, states[40]= 0.000053
Saving checkpoint... 
Iteration: 495674630, states[0] = -84.658661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507630133, states[0] = -84.552541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519585631, states[0] = -84.364825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531023969, states[0] = -84.680780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543485652, states[0] = -46.707311, states[40]= 0.000046
Saving checkpoint... 
Iteration: 554724745, states[0] = 27.766698, states[40]= 0.000049
Saving checkpoint... 
Iteration: 566229260, states[0] = -84.201974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578414587, states[0] = 17.388019, states[40]= 0.000029
Saving checkpoint... 
Iteration: 591244516, states[0] = -84.296914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604271486, states[0] = -84.437567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 617512328, states[0] = -74.062769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629526873, states[0] = -83.305844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642182678, states[0] = -76.952821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654544497, states[0] = -84.006500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666652120, states[0] = -84.588614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678905636, states[0] = -84.228676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691666393, states[0] = -84.618946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703053635, states[0] = 31.500589, states[40]= 0.003015
Saving checkpoint... 
Iteration: 716470354, states[0] = -20.517174, states[40]= 0.000204
Saving checkpoint... 
Iteration: 729185529, states[0] = -75.216356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740219833, states[0] = -84.048799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751965055, states[0] = -84.512064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764238653, states[0] = -84.193556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775688669, states[0] = -84.652452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786842209, states[0] = -59.058288, states[40]= 0.000009
Saving checkpoint... 
Iteration: 799645318, states[0] = -84.547825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810636701, states[0] = -84.517806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822162949, states[0] = -43.109792, states[40]= 0.000068
Saving checkpoint... 
Iteration: 834634787, states[0] = -84.506493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847523925, states[0] = -74.163517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 859677320, states[0] = -84.620666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872866253, states[0] = -81.381070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885056497, states[0] = 31.654747, states[40]= 0.027718
Saving checkpoint... 
Iteration: 897622650, states[0] = -84.444921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909027602, states[0] = -84.647660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920520150, states[0] = -64.592174, states[40]= 0.000004
Saving checkpoint... 
Iteration: 932404192, states[0] = 30.027638, states[40]= 0.000394
Saving checkpoint... 
Iteration: 944856742, states[0] = -67.190846, states[40]= 0.000003
Saving checkpoint... 
Iteration: 957408943, states[0] = 28.792569, states[40]= 0.000117
Saving checkpoint... 
Iteration: 970290285, states[0] = -84.431471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982364398, states[0] = -84.645678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994850316, states[0] = -56.403736, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1007423540, states[0] = 23.575594, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1019906229, states[0] = -84.093603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032287663, states[0] = -84.403288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1043440430, states[0] = 16.030335, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1056407181, states[0] = 30.962405, states[40]= 0.001224
Saving checkpoint... 
Iteration: 1067791456, states[0] = 6.644487, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1080825877, states[0] = -24.981527, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1093295297, states[0] = -84.423487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1105666454, states[0] = -84.558268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116462701, states[0] = 5.293102, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1129083279, states[0] = 29.136134, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1140249581, states[0] = -84.123837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152454678, states[0] = 11.202333, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1164350104, states[0] = -84.593428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176542457, states[0] = -76.617969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188369623, states[0] = -84.631922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200961015, states[0] = -84.391037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213304178, states[0] = -84.433836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1225926142, states[0] = -84.165942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237739069, states[0] = 31.303669, states[40]= 0.051281
Saving checkpoint... 
Iteration: 1249628502, states[0] = -84.382138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261709920, states[0] = -84.636422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273400152, states[0] = 33.346409, states[40]= 0.683167
Saving checkpoint... 
Iteration: 1285861174, states[0] = -52.241555, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1298716469, states[0] = -84.643865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310544091, states[0] = -70.289785, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1322198635, states[0] = -54.828696, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1334831405, states[0] = -16.817887, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1347007255, states[0] = -84.539388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358898910, states[0] = -83.547452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370129170, states[0] = 12.921628, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1382836991, states[0] = -20.481336, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1394957370, states[0] = -84.314970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408948754, states[0] = -84.257058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420934655, states[0] = -84.152126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432696919, states[0] = -84.587579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445662836, states[0] = -84.483725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456980758, states[0] = -84.418118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468246762, states[0] = -83.918290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479383830, states[0] = -84.624706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490797636, states[0] = 15.232514, states[40]= 0.000043
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.538899
 - CaMKt in component CaMK (millimolar): 0.038585
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.803366
 - nass in component intracellular_ions (millimolar): 6.803521
 - ki in component intracellular_ions (millimolar): 144.863984
 - kss in component intracellular_ions (millimolar): 144.863956
 - cansr in component intracellular_ions (millimolar): 2.046094
 - cajsr in component intracellular_ions (millimolar): 1.801900
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010270
 - hf in component INa (dimensionless): 0.571918
 - hs in component INa (dimensionless): 0.571764
 - j in component INa (dimensionless): 0.570926
 - hsp in component INa (dimensionless): 0.324953
 - jp in component INa (dimensionless): 0.570234
 - mL in component INaL (dimensionless): 0.000355
 - hL in component INaL (dimensionless): 0.345439
 - hLp in component INaL (dimensionless): 0.150388
 - a in component Ito (dimensionless): 0.001254
 - iF in component Ito (dimensionless): 0.999200
 - iS in component Ito (dimensionless): 0.365316
 - ap in component Ito (dimensionless): 0.000639
 - iFp in component Ito (dimensionless): 0.999200
 - iSp in component Ito (dimensionless): 0.399479
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842555
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995708
 - jca in component ICaL (dimensionless): 0.998107
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005873
 - xrf in component IKr (dimensionless): 0.000413
 - xrs in component IKr (dimensionless): 0.674957
 - xs1 in component IKs (dimensionless): 0.386299
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996792
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:06:42 (24643): called boinc_finish(0)

</stderr_txt>
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