𝕏

Task 55614679

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_812_1
Workunit 26408227
Created 1 Jul 2024, 15:38:07 UTC
Sent 2 Jul 2024, 3:16:05 UTC
Report deadline 5 Jul 2024, 3:16:05 UTC
Received 2 Jul 2024, 21:50:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 16 min 30 sec
CPU time 1 hours 2 min 38 sec
Validate state Valid
Credit 45.85
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.90 MB
Peak swap size 4.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_812.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_812_1_r1894366354_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_812_1_r1894366354_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.170388
     * GNaL_b in INaL: 0.006108
     * Gto_b in Ito: 0.087843
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031930
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.162292
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.475896
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034713
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12469643, states[0] = -84.306230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25690665, states[0] = -84.261758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36722585, states[0] = -84.227537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49081211, states[0] = 8.526074, states[40]= 0.000327
Saving checkpoint... 
Iteration: 61134818, states[0] = -31.039660, states[40]= 0.000396
Saving checkpoint... 
Iteration: 73733326, states[0] = -84.178122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86430237, states[0] = -84.090396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98349065, states[0] = -83.977015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109542656, states[0] = -84.141541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123316007, states[0] = -83.893945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134820543, states[0] = -84.155616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147067416, states[0] = 15.234084, states[40]= 0.000156
Saving checkpoint... 
Iteration: 160854721, states[0] = -84.151730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172834264, states[0] = -84.151873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185522432, states[0] = -84.126583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197352000, states[0] = -83.970128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209461142, states[0] = -84.096078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220963274, states[0] = -84.143949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233199338, states[0] = -83.066295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245172314, states[0] = -64.132615, states[40]= 0.000006
Saving checkpoint... 
Iteration: 257451407, states[0] = -84.088750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269326609, states[0] = -83.914144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 280864506, states[0] = -84.148397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292797494, states[0] = -84.150850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302857632, states[0] = -84.148540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314395576, states[0] = -84.035498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327334791, states[0] = -83.932945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340239313, states[0] = -83.571482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351781973, states[0] = -84.150855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363861641, states[0] = -84.147967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376213448, states[0] = -83.406652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387934258, states[0] = -84.144151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399198442, states[0] = -82.995713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411746441, states[0] = -84.151022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424583017, states[0] = -84.139850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437520787, states[0] = -84.123382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450526389, states[0] = -84.125259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462462916, states[0] = -84.095142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474882450, states[0] = -84.146333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486216543, states[0] = -83.429824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497614004, states[0] = -84.144175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508042956, states[0] = 24.807701, states[40]= 0.000033
Saving checkpoint... 
Iteration: 520827444, states[0] = -84.148466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533351032, states[0] = -83.965459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544413280, states[0] = -84.054054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556680880, states[0] = -84.149158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568954770, states[0] = -84.141956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580672484, states[0] = -84.148636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592915956, states[0] = -84.143937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604610869, states[0] = -84.143150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615881664, states[0] = -84.145549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627415192, states[0] = -84.055522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639379360, states[0] = -84.011980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651798262, states[0] = -84.148675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664546197, states[0] = -84.130080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678287568, states[0] = -83.793870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690412669, states[0] = -84.052566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701973870, states[0] = -84.140100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715317708, states[0] = -83.888533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727797166, states[0] = -84.148264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739944416, states[0] = -84.141536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751410766, states[0] = -84.050215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764713598, states[0] = -84.148841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776736480, states[0] = -84.148927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789304755, states[0] = -83.850878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 801516871, states[0] = -84.119823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812201851, states[0] = -83.195062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824703986, states[0] = -84.148319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838140143, states[0] = -34.121603, states[40]= 0.000351
Saving checkpoint... 
Iteration: 849338489, states[0] = -83.938016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860907093, states[0] = -84.142840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872869845, states[0] = -84.144615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885199259, states[0] = -83.054260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896417003, states[0] = -84.055763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907822319, states[0] = -84.146400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920132187, states[0] = -27.033921, states[40]= 0.000503
Saving checkpoint... 
Iteration: 932207042, states[0] = -83.330441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944021491, states[0] = 30.594235, states[40]= 0.000993
Saving checkpoint... 
Iteration: 955231181, states[0] = -83.520322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967724945, states[0] = -84.147779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978432583, states[0] = -84.069665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991832138, states[0] = -84.145542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003990656, states[0] = -84.137376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015938369, states[0] = -84.140260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027606622, states[0] = -84.140115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039611746, states[0] = -84.140730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1052350730, states[0] = -83.961817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064814000, states[0] = -84.145776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077355875, states[0] = -83.971287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088209228, states[0] = -83.360227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099930469, states[0] = -84.140202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111991537, states[0] = -84.136695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124343294, states[0] = -83.946575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136629404, states[0] = -84.142201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147906522, states[0] = -84.141196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160159883, states[0] = -51.916537, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1173405968, states[0] = -84.042545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185396534, states[0] = -84.031520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198271446, states[0] = -83.726717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210039383, states[0] = 26.034362, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1222112108, states[0] = -8.663969, states[40]= 0.000802
Saving checkpoint... 
Iteration: 1234156028, states[0] = -48.374960, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1247869608, states[0] = -84.142440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258780338, states[0] = -84.145596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270388699, states[0] = -84.021118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283126603, states[0] = -22.009141, states[40]= 0.000478
Saving checkpoint... 
Iteration: 1295106791, states[0] = -4.468700, states[40]= 0.000887
Saving checkpoint... 
Iteration: 1307610890, states[0] = -84.139057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320015895, states[0] = 30.899525, states[40]= 0.007024
Saving checkpoint... 
Iteration: 1332385077, states[0] = -84.015910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345042798, states[0] = 24.864962, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1356867581, states[0] = -84.141899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369007569, states[0] = 28.967526, states[40]= 0.130794
Saving checkpoint... 
Iteration: 1380908830, states[0] = -84.139718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393557719, states[0] = -84.128820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405355105, states[0] = -83.967944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418348212, states[0] = -83.954762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430895201, states[0] = -84.140127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443469324, states[0] = -84.093363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455681061, states[0] = -84.143929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467940826, states[0] = -84.137490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479730787, states[0] = -84.144825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492310140, states[0] = -83.862772, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.009880
 - CaMKt in component CaMK (millimolar): 0.005183
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.307499
 - nass in component intracellular_ions (millimolar): 6.307607
 - ki in component intracellular_ions (millimolar): 145.555136
 - kss in component intracellular_ions (millimolar): 145.555120
 - cansr in component intracellular_ions (millimolar): 1.689118
 - cajsr in component intracellular_ions (millimolar): 1.688454
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.010829
 - hf in component INa (dimensionless): 0.550515
 - hs in component INa (dimensionless): 0.550521
 - j in component INa (dimensionless): 0.550548
 - hsp in component INa (dimensionless): 0.306634
 - jp in component INa (dimensionless): 0.550563
 - mL in component INaL (dimensionless): 0.000392
 - hL in component INaL (dimensionless): 0.386005
 - hLp in component INaL (dimensionless): 0.208219
 - a in component Ito (dimensionless): 0.001299
 - iF in component Ito (dimensionless): 0.999123
 - iS in component Ito (dimensionless): 0.845827
 - ap in component Ito (dimensionless): 0.000662
 - iFp in component Ito (dimensionless): 0.999123
 - iSp in component Ito (dimensionless): 0.874767
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973284
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003208
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.210546
 - xs1 in component IKs (dimensionless): 0.133401
 - xs2 in component IKs (dimensionless): 0.000297
 - xk1 in component IK1 (dimensionless): 0.996916
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
13:49:35 (25437): called boinc_finish(0)

</stderr_txt>
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