𝕏

Task 55614677

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_712_1
Workunit 26408226
Created 1 Jul 2024, 15:38:07 UTC
Sent 2 Jul 2024, 3:16:05 UTC
Report deadline 5 Jul 2024, 3:16:05 UTC
Received 2 Jul 2024, 19:42:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 15 min 45 sec
CPU time 1 hours 2 min 33 sec
Validate state Valid
Credit 43.69
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.91 MB
Peak swap size 4.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_712.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_712_1_r1764419590_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_712_1_r1764419590_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.475269
     * GNaL_b in INaL: 0.005707
     * Gto_b in Ito: 0.087972
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031608
     * GKs_b in IKs: 0.001949
     * GK1_b in IK1: 0.168127
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.200511
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035994
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11433038, states[0] = -84.327309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23562365, states[0] = -84.293233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36239043, states[0] = -83.721187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47202395, states[0] = -83.439964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59592280, states[0] = -84.226540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70452836, states[0] = -84.167004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82887147, states[0] = -84.216070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95375185, states[0] = -84.076913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108139742, states[0] = -34.288018, states[40]= 0.000342
Saving checkpoint... 
Iteration: 120621953, states[0] = -84.203180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131299177, states[0] = -83.905412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143706518, states[0] = -84.205305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155239551, states[0] = -83.651845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168466854, states[0] = -84.152535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180109035, states[0] = -6.309444, states[40]= 0.000875
Saving checkpoint... 
Iteration: 192101293, states[0] = -0.951231, states[40]= 0.000842
Saving checkpoint... 
Iteration: 205681634, states[0] = -84.201518, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217125747, states[0] = -21.346018, states[40]= 0.000479
Saving checkpoint... 
Iteration: 228789957, states[0] = -84.201584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241219595, states[0] = -83.533315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254278895, states[0] = -83.830332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264966166, states[0] = -84.193785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276808432, states[0] = -84.200594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289866286, states[0] = -84.198408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302380429, states[0] = -84.070740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315146335, states[0] = -39.725610, states[40]= 0.000201
Saving checkpoint... 
Iteration: 327888507, states[0] = -84.197171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340140294, states[0] = -34.334336, states[40]= 0.000349
Saving checkpoint... 
Iteration: 352675312, states[0] = -84.199794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364912407, states[0] = -84.195818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378325947, states[0] = -83.971703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390526767, states[0] = -84.176179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403565465, states[0] = -84.186447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415795647, states[0] = -84.200044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427844609, states[0] = -84.198418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 439772738, states[0] = -84.200372, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451349413, states[0] = -84.020390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 464574396, states[0] = -84.187930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476612496, states[0] = -84.193891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488989602, states[0] = -84.191123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502223080, states[0] = -83.552872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515490403, states[0] = -84.161209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528998055, states[0] = -84.190439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541953177, states[0] = -84.192735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554208059, states[0] = -83.442060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565747529, states[0] = -84.199903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579294005, states[0] = -83.881568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591707788, states[0] = -84.199467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603287698, states[0] = -83.860152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615327031, states[0] = -83.972840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627256128, states[0] = -83.730868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639931554, states[0] = -84.193271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652233326, states[0] = -83.611803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664414805, states[0] = -84.108276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677016968, states[0] = 30.825190, states[40]= 0.004824
Saving checkpoint... 
Iteration: 689504266, states[0] = -84.166244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701329970, states[0] = -83.979073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713062887, states[0] = 17.068340, states[40]= 0.000122
Saving checkpoint... 
Iteration: 725603688, states[0] = -84.191289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738336197, states[0] = -83.992484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750889908, states[0] = -84.194636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763949436, states[0] = -84.191642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776635608, states[0] = -84.194636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788466171, states[0] = -84.146872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 801306557, states[0] = -83.918720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813079775, states[0] = 9.869282, states[40]= 0.000329
Saving checkpoint... 
Iteration: 825694666, states[0] = -84.197785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837864303, states[0] = -84.195256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851288374, states[0] = -83.861026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863139353, states[0] = -33.490399, states[40]= 0.000375
Saving checkpoint... 
Iteration: 874616514, states[0] = -84.192075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887250437, states[0] = -83.701642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899998246, states[0] = -84.188279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912201762, states[0] = -83.320261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923298974, states[0] = -83.895353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936021396, states[0] = 30.512076, states[40]= 0.001028
Saving checkpoint... 
Iteration: 948472151, states[0] = -84.149375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961188872, states[0] = -81.117542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973501836, states[0] = -84.163596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986701850, states[0] = -84.197049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998982907, states[0] = -84.188525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009688024, states[0] = -84.196503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021346914, states[0] = -84.012353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035003959, states[0] = 29.952077, states[40]= 0.458662
Saving checkpoint... 
Iteration: 1047791832, states[0] = -84.196475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058838962, states[0] = -84.194974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070989341, states[0] = -84.187765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1083286965, states[0] = -83.854739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095548084, states[0] = -84.178304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1108205375, states[0] = -83.402039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121005468, states[0] = 28.687828, states[40]= 0.272222
Saving checkpoint... 
Iteration: 1133201268, states[0] = -83.302274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145890002, states[0] = -84.192343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158212922, states[0] = -83.482482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171673714, states[0] = -84.194967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183078863, states[0] = 10.275123, states[40]= 0.000312
Saving checkpoint... 
Iteration: 1194995527, states[0] = -84.186715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209244878, states[0] = -83.671350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220325520, states[0] = -83.965733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233340575, states[0] = -83.998656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244878007, states[0] = -84.192310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256027390, states[0] = 29.408614, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1268784388, states[0] = -84.195359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280675424, states[0] = -84.194417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292271118, states[0] = -83.793194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303671588, states[0] = -84.194097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316341586, states[0] = -84.000208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327727883, states[0] = -84.195472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340659438, states[0] = -84.193196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353071492, states[0] = 13.474928, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1365128323, states[0] = -23.649945, states[40]= 0.000498
Saving checkpoint... 
Iteration: 1376920461, states[0] = -84.189554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389099014, states[0] = 0.422225, states[40]= 0.000792
Saving checkpoint... 
Iteration: 1401429077, states[0] = -84.116937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1413170230, states[0] = -62.274690, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1424211299, states[0] = -83.467958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436192506, states[0] = -82.375944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447461828, states[0] = -84.140423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459346255, states[0] = -84.008525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471730223, states[0] = -84.194652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485332631, states[0] = -83.980393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496869672, states[0] = -84.191212, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.060645
 - CaMKt in component CaMK (millimolar): 0.005186
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.339740
 - nass in component intracellular_ions (millimolar): 6.339847
 - ki in component intracellular_ions (millimolar): 145.522734
 - kss in component intracellular_ions (millimolar): 145.522718
 - cansr in component intracellular_ions (millimolar): 1.690605
 - cajsr in component intracellular_ions (millimolar): 1.689985
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.010774
 - hf in component INa (dimensionless): 0.552578
 - hs in component INa (dimensionless): 0.552584
 - j in component INa (dimensionless): 0.552609
 - hsp in component INa (dimensionless): 0.308409
 - jp in component INa (dimensionless): 0.552622
 - mL in component INaL (dimensionless): 0.000389
 - hL in component INaL (dimensionless): 0.387603
 - hLp in component INaL (dimensionless): 0.209378
 - a in component Ito (dimensionless): 0.001295
 - iF in component Ito (dimensionless): 0.999131
 - iS in component Ito (dimensionless): 0.846192
 - ap in component Ito (dimensionless): 0.000660
 - iFp in component Ito (dimensionless): 0.999131
 - iSp in component Ito (dimensionless): 0.875249
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973357
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003214
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.209493
 - xs1 in component IKs (dimensionless): 0.133217
 - xs2 in component IKs (dimensionless): 0.000296
 - xk1 in component IK1 (dimensionless): 0.996904
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
11:48:16 (24379): called boinc_finish(0)

</stderr_txt>
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