𝕏

Task 55614675

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_612_1
Workunit 26408225
Created 1 Jul 2024, 15:38:07 UTC
Sent 2 Jul 2024, 3:16:05 UTC
Report deadline 5 Jul 2024, 3:16:05 UTC
Received 2 Jul 2024, 21:50:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 16 min 19 sec
CPU time 1 hours 2 min 38 sec
Validate state Valid
Credit 44.87
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.91 MB
Peak swap size 4.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_612.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_612_1_r618328777_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Schmidt_2000-conf_612_1_r618328777_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.347407
     * GNaL_b in INaL: 0.005636
     * Gto_b in Ito: 0.087769
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031668
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.161427
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.010970
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032143
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12222174, states[0] = -83.752256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23934572, states[0] = -84.253007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35815737, states[0] = -84.217252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48560674, states[0] = -84.177292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60486801, states[0] = -84.135631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71601964, states[0] = -84.160409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82601970, states[0] = -84.153345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93952027, states[0] = -84.148331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 105197196, states[0] = -82.869256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116374600, states[0] = -84.002647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128411998, states[0] = -84.048241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140766034, states[0] = -84.145409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151915175, states[0] = -84.138514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164893267, states[0] = -84.138698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176862814, states[0] = -84.139523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189645333, states[0] = -84.139174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 202743767, states[0] = -84.142031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214843504, states[0] = -84.139183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226372485, states[0] = -83.991338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239686209, states[0] = -84.140489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 250699773, states[0] = -84.140781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263329083, states[0] = -83.905771, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276272465, states[0] = -83.719730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288911107, states[0] = -84.135037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 300369157, states[0] = -83.985264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311528000, states[0] = -84.115239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322604048, states[0] = -84.132757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335291190, states[0] = -83.792956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346736072, states[0] = -84.140471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359290775, states[0] = -83.791313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370049330, states[0] = 22.517051, states[40]= 0.000043
Saving checkpoint... 
Iteration: 381465594, states[0] = -84.085445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394349917, states[0] = -83.950341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406090951, states[0] = 4.733049, states[40]= 0.000515
Saving checkpoint... 
Iteration: 419111470, states[0] = -8.113878, states[40]= 0.000762
Saving checkpoint... 
Iteration: 431273332, states[0] = -83.722397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444335510, states[0] = -83.919611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455725478, states[0] = -84.139771, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469450151, states[0] = -84.074426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479873389, states[0] = -84.135732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492310510, states[0] = -83.854645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505007108, states[0] = 28.787048, states[40]= 0.154855
Saving checkpoint... 
Iteration: 516392888, states[0] = -84.018096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529384443, states[0] = -84.006762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541638928, states[0] = -84.135483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554541610, states[0] = -84.118049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566374599, states[0] = -83.992175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577927925, states[0] = -84.132338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591132204, states[0] = -26.956779, states[40]= 0.000480
Saving checkpoint... 
Iteration: 603042135, states[0] = 25.126617, states[40]= 0.000027
Saving checkpoint... 
Iteration: 615445905, states[0] = -84.070381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627553792, states[0] = -84.120974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638909049, states[0] = -84.132988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650330222, states[0] = -83.906026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662912211, states[0] = -84.132677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676456290, states[0] = -84.077545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687866029, states[0] = -84.134838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701229685, states[0] = -83.492994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713943835, states[0] = -84.130647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725800022, states[0] = -84.137173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736844625, states[0] = -84.135494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 749306790, states[0] = -83.841957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761403234, states[0] = -84.029198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774102211, states[0] = -1.408962, states[40]= 0.000778
Saving checkpoint... 
Iteration: 785111442, states[0] = -8.087573, states[40]= 0.000763
Saving checkpoint... 
Iteration: 796733578, states[0] = -84.137772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807817605, states[0] = -84.136116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818435166, states[0] = -84.060538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831269728, states[0] = -83.704247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841659522, states[0] = -84.135284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852588587, states[0] = -84.127100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864173893, states[0] = -65.309973, states[40]= 0.000005
Saving checkpoint... 
Iteration: 876011150, states[0] = 30.157178, states[40]= 0.037443
Saving checkpoint... 
Iteration: 887996830, states[0] = -84.126568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900366126, states[0] = -83.976620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912785061, states[0] = -84.136459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924707015, states[0] = -84.136731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938644634, states[0] = -84.133610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950898031, states[0] = -84.131700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963515033, states[0] = -84.106615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976202536, states[0] = -83.175789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989649658, states[0] = -84.133706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003053235, states[0] = 21.027594, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1013442302, states[0] = -84.065203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027672010, states[0] = -84.134898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039127901, states[0] = -23.109143, states[40]= 0.000462
Saving checkpoint... 
Iteration: 1050588034, states[0] = -84.125822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062680373, states[0] = -84.135082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1074957275, states[0] = -84.127735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1086087249, states[0] = 6.519790, states[40]= 0.000430
Saving checkpoint... 
Iteration: 1099145745, states[0] = -38.957444, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1110964335, states[0] = -84.127118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123547114, states[0] = -84.116226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136092114, states[0] = 4.158583, states[40]= 0.000543
Saving checkpoint... 
Iteration: 1147493766, states[0] = -84.096360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160871039, states[0] = -84.131782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174303565, states[0] = -83.829372, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185712191, states[0] = -84.135268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199581986, states[0] = -84.123830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1211314769, states[0] = -83.862492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223550021, states[0] = -84.116424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1235380570, states[0] = -83.997027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247920687, states[0] = -84.128734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260925160, states[0] = -84.128414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273170497, states[0] = -61.759411, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1285260317, states[0] = -83.657829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296742713, states[0] = -84.134782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309868258, states[0] = -84.131024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322252850, states[0] = -83.620204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334597093, states[0] = -84.125641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346471566, states[0] = -84.083320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359103592, states[0] = -2.282030, states[40]= 0.000798
Saving checkpoint... 
Iteration: 1370297268, states[0] = -83.807680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381677169, states[0] = -84.133038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394541218, states[0] = -84.112921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407994531, states[0] = -84.123598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420921245, states[0] = -84.127671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433910076, states[0] = -84.128191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446472417, states[0] = -84.083225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459568215, states[0] = -84.119461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472194187, states[0] = -82.254452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484446193, states[0] = -84.065397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495412257, states[0] = -84.034765, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.998667
 - CaMKt in component CaMK (millimolar): 0.005217
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.315080
 - nass in component intracellular_ions (millimolar): 6.315187
 - ki in component intracellular_ions (millimolar): 145.545911
 - kss in component intracellular_ions (millimolar): 145.545895
 - cansr in component intracellular_ions (millimolar): 1.692179
 - cajsr in component intracellular_ions (millimolar): 1.691499
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.010841
 - hf in component INa (dimensionless): 0.550059
 - hs in component INa (dimensionless): 0.550065
 - j in component INa (dimensionless): 0.550092
 - hsp in component INa (dimensionless): 0.306242
 - jp in component INa (dimensionless): 0.550107
 - mL in component INaL (dimensionless): 0.000393
 - hL in component INaL (dimensionless): 0.385651
 - hLp in component INaL (dimensionless): 0.207941
 - a in component Ito (dimensionless): 0.001300
 - iF in component Ito (dimensionless): 0.999121
 - iS in component Ito (dimensionless): 0.845655
 - ap in component Ito (dimensionless): 0.000663
 - iFp in component Ito (dimensionless): 0.999121
 - iSp in component Ito (dimensionless): 0.874573
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973264
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003229
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.210804
 - xs1 in component IKs (dimensionless): 0.133437
 - xs2 in component IKs (dimensionless): 0.000298
 - xk1 in component IK1 (dimensionless): 0.996919
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
14:13:56 (25653): called boinc_finish(0)

</stderr_txt>
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