𝕏

Task 55614590

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_412_0
Workunit 26408183
Created 1 Jul 2024, 15:38:02 UTC
Sent 2 Jul 2024, 3:16:05 UTC
Report deadline 5 Jul 2024, 3:16:05 UTC
Received 2 Jul 2024, 21:50:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 15 min 17 sec
CPU time 1 hours 2 min 3 sec
Validate state Valid
Credit 44.41
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.68 MB
Peak swap size 4.10 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_412.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_412_0_r954086366_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pieske_500-conf_412_0_r954086366_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.561886
     * GNaL_b in INaL: 0.005721
     * Gto_b in Ito: 0.086924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031735
     * GKs_b in IKs: 0.001928
     * GK1_b in IK1: 0.159517
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.317910
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033723
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11152358, states[0] = -87.309489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22673519, states[0] = -87.327403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35187260, states[0] = -87.342066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47489343, states[0] = -87.422176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59020334, states[0] = 20.595176, states[40]= 0.009716
Saving checkpoint... 
Iteration: 72097961, states[0] = -45.433826, states[40]= 0.000058
Saving checkpoint... 
Iteration: 85982032, states[0] = -87.400209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97853447, states[0] = -52.109466, states[40]= 0.000021
Saving checkpoint... 
Iteration: 110253392, states[0] = 31.674695, states[40]= 0.133983
Saving checkpoint... 
Iteration: 122472757, states[0] = -87.383511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135412331, states[0] = -87.251237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148870861, states[0] = -76.761921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161197051, states[0] = -87.336764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172090085, states[0] = -35.617698, states[40]= 0.000232
Saving checkpoint... 
Iteration: 185444373, states[0] = -87.330966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198205225, states[0] = -87.352487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211504441, states[0] = 28.371733, states[40]= 0.133946
Saving checkpoint... 
Iteration: 223038328, states[0] = 12.564379, states[40]= 0.006124
Saving checkpoint... 
Iteration: 235428785, states[0] = -87.294925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247526628, states[0] = 18.271488, states[40]= 0.007330
Saving checkpoint... 
Iteration: 259622448, states[0] = -79.043961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272019624, states[0] = 20.905469, states[40]= 0.010285
Saving checkpoint... 
Iteration: 283659807, states[0] = -87.242686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297054639, states[0] = 2.636605, states[40]= 0.005288
Saving checkpoint... 
Iteration: 309478841, states[0] = -87.391013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321242207, states[0] = -87.408720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335336519, states[0] = -31.339005, states[40]= 0.000385
Saving checkpoint... 
Iteration: 347963873, states[0] = -87.367640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359826333, states[0] = -19.009555, states[40]= 0.001169
Saving checkpoint... 
Iteration: 372371606, states[0] = -77.838879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385635938, states[0] = -86.896074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397351865, states[0] = -49.975026, states[40]= 0.000029
Saving checkpoint... 
Iteration: 410219688, states[0] = -87.377116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423398732, states[0] = -87.202069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434397586, states[0] = -87.195795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445990517, states[0] = -87.406496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456770902, states[0] = 20.482476, states[40]= 0.009371
Saving checkpoint... 
Iteration: 468441417, states[0] = -87.324170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481271603, states[0] = 20.238679, states[40]= 0.008974
Saving checkpoint... 
Iteration: 493711225, states[0] = -87.362931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506597919, states[0] = -45.073970, states[40]= 0.000061
Saving checkpoint... 
Iteration: 519494227, states[0] = -87.410966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532185367, states[0] = -87.310462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543746072, states[0] = -87.413132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556932666, states[0] = -87.304055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567857528, states[0] = -57.232039, states[40]= 0.000009
Saving checkpoint... 
Iteration: 580451252, states[0] = -87.344389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593584002, states[0] = -28.313922, states[40]= 0.000523
Saving checkpoint... 
Iteration: 606187480, states[0] = -87.315252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619076725, states[0] = -19.487144, states[40]= 0.001119
Saving checkpoint... 
Iteration: 631075566, states[0] = -18.074304, states[40]= 0.001276
Saving checkpoint... 
Iteration: 642154330, states[0] = -87.224694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654679395, states[0] = -87.295980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667247802, states[0] = -87.415018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679303921, states[0] = 3.137705, states[40]= 0.005342
Saving checkpoint... 
Iteration: 690210840, states[0] = -87.362055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703450080, states[0] = -87.341954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715492730, states[0] = -87.408954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727327465, states[0] = -20.389174, states[40]= 0.001032
Saving checkpoint... 
Iteration: 738934973, states[0] = -87.309329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751966140, states[0] = -87.371019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761663381, states[0] = -87.252814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774175870, states[0] = -87.286958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785643816, states[0] = -87.164938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798429709, states[0] = -87.296608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810263435, states[0] = 22.557915, states[40]= 0.022953
Saving checkpoint... 
Iteration: 822558059, states[0] = 0.115853, states[40]= 0.004957
Saving checkpoint... 
Iteration: 834896279, states[0] = -87.186929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846824448, states[0] = -16.713730, states[40]= 0.001454
Saving checkpoint... 
Iteration: 859660498, states[0] = -87.244177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872752277, states[0] = 37.128358, states[40]= 0.104128
Saving checkpoint... 
Iteration: 884640815, states[0] = -87.116666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895885606, states[0] = -86.867122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907131072, states[0] = -86.073727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920813359, states[0] = -4.397875, states[40]= 0.004096
Saving checkpoint... 
Iteration: 932953353, states[0] = -87.348088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943578651, states[0] = -21.833544, states[40]= 0.000911
Saving checkpoint... 
Iteration: 955746118, states[0] = -87.412764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969093241, states[0] = -39.390488, states[40]= 0.000140
Saving checkpoint... 
Iteration: 981818564, states[0] = -9.773910, states[40]= 0.002800
Saving checkpoint... 
Iteration: 993930315, states[0] = -87.297900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005805866, states[0] = 1.760165, states[40]= 0.005184
Saving checkpoint... 
Iteration: 1017794550, states[0] = 9.068026, states[40]= 0.005827
Saving checkpoint... 
Iteration: 1031072345, states[0] = -14.174687, states[40]= 0.001863
Saving checkpoint... 
Iteration: 1043603710, states[0] = -52.303891, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1056803059, states[0] = 3.728152, states[40]= 0.005402
Saving checkpoint... 
Iteration: 1069598617, states[0] = -45.932212, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1082467244, states[0] = -87.372493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094990544, states[0] = -87.405864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106189844, states[0] = -87.320051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119107208, states[0] = -56.810899, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1132306665, states[0] = 1.173408, states[40]= 0.005108
Saving checkpoint... 
Iteration: 1144641567, states[0] = -87.131792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156440101, states[0] = -87.320569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168854898, states[0] = -53.819422, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1180917216, states[0] = -87.263321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192852659, states[0] = -50.973002, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1206185262, states[0] = -87.309522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217892833, states[0] = -87.152164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231108455, states[0] = -58.456342, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1242768507, states[0] = 21.252258, states[40]= 0.011352
Saving checkpoint... 
Iteration: 1254526260, states[0] = 18.428029, states[40]= 0.007406
Saving checkpoint... 
Iteration: 1265976501, states[0] = -87.386639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277858614, states[0] = -58.667949, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1291560760, states[0] = -2.074801, states[40]= 0.004582
Saving checkpoint... 
Iteration: 1304665519, states[0] = -87.258405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317647320, states[0] = -87.193279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329956483, states[0] = -87.353556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343359183, states[0] = -59.429268, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1356955340, states[0] = -87.351407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370220642, states[0] = -87.377636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381818724, states[0] = -9.952998, states[40]= 0.002758
Saving checkpoint... 
Iteration: 1393841173, states[0] = -36.908268, states[40]= 0.000196
Saving checkpoint... 
Iteration: 1406376969, states[0] = -83.991521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418325191, states[0] = -17.616529, states[40]= 0.001333
Saving checkpoint... 
Iteration: 1430884481, states[0] = -86.748932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443760942, states[0] = 23.119894, states[40]= 0.037763
Saving checkpoint... 
Iteration: 1455155961, states[0] = -87.229345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468227849, states[0] = -87.388395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480104640, states[0] = -53.488480, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1492589489, states[0] = -34.892955, states[40]= 0.000254
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.292420
 - CaMKt in component CaMK (millimolar): 0.019360
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.714803
 - nass in component intracellular_ions (millimolar): 6.714903
 - ki in component intracellular_ions (millimolar): 145.243001
 - kss in component intracellular_ions (millimolar): 145.242974
 - cansr in component intracellular_ions (millimolar): 1.422772
 - cajsr in component intracellular_ions (millimolar): 1.205324
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007789
 - hf in component INa (dimensionless): 0.677462
 - hs in component INa (dimensionless): 0.677358
 - j in component INa (dimensionless): 0.676639
 - hsp in component INa (dimensionless): 0.430909
 - jp in component INa (dimensionless): 0.674633
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.385555
 - hLp in component INaL (dimensionless): 0.180229
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999506
 - iS in component Ito (dimensionless): 0.292296
 - ap in component Ito (dimensionless): 0.000531
 - iFp in component Ito (dimensionless): 0.999506
 - iSp in component Ito (dimensionless): 0.339647
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857536
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991047
 - jca in component ICaL (dimensionless): 0.991314
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004172
 - xrf in component IKr (dimensionless): 0.001787
 - xrs in component IKr (dimensionless): 0.671921
 - xs1 in component IKs (dimensionless): 0.384250
 - xs2 in component IKs (dimensionless): 0.000215
 - xk1 in component IK1 (dimensionless): 0.996912
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:20:37 (26166): called boinc_finish(0)

</stderr_txt>
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